Neuroprotective effects of macranthoin G from Eucommia ulmoides against hydrogen peroxide-induced apoptosis in PC12 cells via inhibiting NF-κB activation

Chemico-Biological Interactions

Volumn 224, Issue , 2014, Pages 108-116

  Hu, Weicheng ^a   Wang, Gongcheng ^b   Li, Pengxia ^c   Wang, Yuning ^c   Si, Chuan Ling ^d   He, Jing ^a,e   Long, Wei ^f   Bai, Yujia ^e   Feng, Zuoshan ^e   Wang, Xinfeng ^a  

^a HUAIYIN NORMAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^e XINJIANG AGRICULTURAL UNIVERSITY   (China)

^f INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

Antioxidant enzyme; Macranthoin G; Malondialdehyde; Mitochondria membrane potential; Reactive oxygen species

Indexed keywords

CASPASE 3; CATALASE; EUCOMMIA ULMOIDES EXTRACT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACRANTHOIN G; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; ANTIOXIDANT; CHLOROGENIC ACID; I KAPPA B KINASE ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RELA PROTEIN, RAT; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOCHEMICAL COMPOSITION; CELL LEVEL; CELL STRESS; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PC12 CELL LINE; PILOT STUDY; PROTEIN PHOSPHORYLATION; RAT; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; EUCOMMIACEAE; LIPID PEROXIDATION; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CATALASE; CHLOROGENIC ACID; EUCOMMIACEAE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MALONDIALDEHYDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROPROTECTIVE AGENTS; NF-KAPPAB INHIBITOR ALPHA; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PC12 CELLS; PHOSPHORYLATION; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA;

EID: 84910042580     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.10.011     Document Type: Article

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