메뉴 건너뛰기




Volumn 57, Issue 6, 2009, Pages 2576-2582

Modulation of Akt, JNK, and p38 activation is involved in citrus flavonoid-mediated cytoprotection of PC12 cells challenged by hydrogen peroxide

Author keywords

Akt; Antioxidant; Hesperetin; Isorhamnetin; Isosakuranetin; Neuroprotection; Signaling molecules

Indexed keywords

FLAVONOID; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

EID: 64549139702     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf8033607     Document Type: Article
Times cited : (70)

References (38)
  • 1
    • 0030007912 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease and other neurodegenerative disorders
    • Jenner, P. Oxidative stress in Parkinson's disease and other neurodegenerative disorders. Pathol. Biol. 1996, 44, 57-64.
    • (1996) Pathol. Biol , vol.44 , pp. 57-64
    • Jenner, P.1
  • 2
    • 0344824654 scopus 로고    scopus 로고
    • Amyloid β-peptide [1-42]-associated free radical-induced oxidative stress and neurodegeneration in Alzheimer's disease brain: Mechanisms and consequences
    • Butterfield, D. A. Amyloid β-peptide [1-42]-associated free radical-induced oxidative stress and neurodegeneration in Alzheimer's disease brain: mechanisms and consequences. Curr. Med. Chem. 2003, 10, 2651-2659.
    • (2003) Curr. Med. Chem , vol.10 , pp. 2651-2659
    • Butterfield, D.A.1
  • 3
    • 4644360633 scopus 로고    scopus 로고
    • Warner, D. S.; Sheng, H.; Batinic-Haberle, I. Oxidants, antioxidants and the ischemic brain. J. Exp. Biol. 2004207, 3221-3231.
    • Warner, D. S.; Sheng, H.; Batinic-Haberle, I. Oxidants, antioxidants and the ischemic brain. J. Exp. Biol. 2004207, 3221-3231.
  • 5
    • 0035895957 scopus 로고    scopus 로고
    • The neuroprotective effects of phytoestrogens on amyloid β protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons
    • Wang. C.-N.: Chi, C.-W.; Lin, Y.-L.; Chen, C.-R: Shiao. Y.-J. The neuroprotective effects of phytoestrogens on amyloid β protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons. J. Biol. Chem. 2001, 276, 5287-5295.
    • (2001) J. Biol. Chem , vol.276 , pp. 5287-5295
    • Wang, C.-N.1    Chi, C.-W.2    Lin, Y.-L.3    Chen, C.-R.4    Shiao, Y.-J.5
  • 6
    • 40849085134 scopus 로고    scopus 로고
    • Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells
    • Crespo, I.; García-Mediavilla, M. V.; Almar, M.; González, P.; Tuñón, M. J.; Sánchez-Campos, S.: González- Gallego, J. Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells. Food Chem. Toxicol. 2008, 46, 1555-1536.
    • (2008) Food Chem. Toxicol , vol.46 , pp. 1555-1536
    • Crespo, I.1    García-Mediavilla, M.V.2    Almar, M.3    González, P.4    Tuñón, M.J.5    Sánchez-Campos, S.6    González- Gallego, J.7
  • 9
    • 0036830947 scopus 로고    scopus 로고
    • Calcium dyshomeostasis and intracellular signaling in Alzheimer's disease
    • LaFerla, F. M. Calcium dyshomeostasis and intracellular signaling in Alzheimer's disease. Nat. Rev. Neurosci. 2002, 3, 862-872.
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 862-872
    • LaFerla, F.M.1
  • 10
    • 33751079341 scopus 로고    scopus 로고
    • Phospholipases A2 mediate amyloid-beat peptide-induced mitochondrial dysfunction
    • Zhu, D.; Lai, Y.; Shelat, P. B.; Hu, C.; Sun, G. Y.; Lee, J. C. Phospholipases A2 mediate amyloid-beat peptide-induced mitochondrial dysfunction. J. Neurosci. 2006, 26, 11111-11119.
    • (2006) J. Neurosci , vol.26 , pp. 11111-11119
    • Zhu, D.1    Lai, Y.2    Shelat, P.B.3    Hu, C.4    Sun, G.Y.5    Lee, J.C.6
  • 12
    • 0035150315 scopus 로고    scopus 로고
    • Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
    • Erlund, I.; Meririnne, E.; Alfthan, G.; Aro, A. Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice. J. Nutr. 2001, 131, 235-241.
    • (2001) J. Nutr , vol.131 , pp. 235-241
    • Erlund, I.1    Meririnne, E.2    Alfthan, G.3    Aro, A.4
  • 13
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson, M. P. Pathways towards and away from Alzheimer's disease, Nature 2004, 430, 631-107.
    • (2004) Nature , vol.430 , pp. 631-107
    • Mattson, M.P.1
  • 14
    • 0034137655 scopus 로고    scopus 로고
    • Signal transduction events elicited by natural products: Role of MAPK and caspase pathways in homeostatic response and induction of apoptosis
    • Kong, A-N. T.; Yu, R.; Chen, C.; Mandlekar, S.; Primiano, T. Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis. Arch. Pharm. Res. 2000, 23, 1-16.
    • (2000) Arch. Pharm. Res , vol.23 , pp. 1-16
    • Kong, A.-N.T.1    Yu, R.2    Chen, C.3    Mandlekar, S.4    Primiano, T.5
  • 15
    • 0034494884 scopus 로고    scopus 로고
    • Respective bioavailability of quercetin aglycone and its glycosides in a rat model
    • Morand, C.; Manach, C.; Crespy, V.; Remesy, C. Respective bioavailability of quercetin aglycone and its glycosides in a rat model. Biofactors 2000, 12, 169-74.
    • (2000) Biofactors , vol.12 , pp. 169-174
    • Morand, C.1    Manach, C.2    Crespy, V.3    Remesy, C.4
  • 17
    • 0035879699 scopus 로고    scopus 로고
    • Estimation of lipid peroxidation of live cells using a fluorescent probe, Diphenyl-1-pyrenylphosphine
    • Takahashi, M.; Shibata, M.; Niki, E. Estimation of lipid peroxidation of live cells using a fluorescent probe, Diphenyl-1-pyrenylphosphine. Free Radical Biol. Med. 2001, 31, 164-174.
    • (2001) Free Radical Biol. Med , vol.31 , pp. 164-174
    • Takahashi, M.1    Shibata, M.2    Niki, E.3
  • 18
    • 31344481924 scopus 로고    scopus 로고
    • Involvement of apoptosis in malathion-induced cytotoxicity in a grass carp (Ctenopharyngodon idellus) cell line
    • Chen, X.; Shao, J.; Xiang, L.; Liu, X. Involvement of apoptosis in malathion-induced cytotoxicity in a grass carp (Ctenopharyngodon idellus) cell line. Comp. Biochem. Physiol., Part C 2006, 142, 36-45.
    • (2006) Comp. Biochem. Physiol., Part C , vol.142 , pp. 36-45
    • Chen, X.1    Shao, J.2    Xiang, L.3    Liu, X.4
  • 19
    • 0014756187 scopus 로고
    • Measurement of catalase in tissue extracts
    • Cohen, P. D.; Marcus, J. Measurement of catalase in tissue extracts. Anal. Biochem. 1970, 34, 30-38.
    • (1970) Anal. Biochem , vol.34 , pp. 30-38
    • Cohen, P.D.1    Marcus, J.2
  • 20
    • 0037403445 scopus 로고    scopus 로고
    • Tamoxifen in induction of aryl sulfotransferase and hydroxysteroid sulfotransferase in male and female rat liver and intestine
    • Maiti, S.; Chen, G. Tamoxifen in induction of aryl sulfotransferase and hydroxysteroid sulfotransferase in male and female rat liver and intestine. Drug Metab. Dispos. 2003, 31, 637-644.
    • (2003) Drug Metab. Dispos , vol.31 , pp. 637-644
    • Maiti, S.1    Chen, G.2
  • 21
    • 0037044838 scopus 로고    scopus 로고
    • 2 induce caspase-3- independent degradation of Akt/Protein Kinase B. J. Biol. Chem. 2002, 277, 42943-42952.
    • 2 induce caspase-3- independent degradation of Akt/Protein Kinase B. J. Biol. Chem. 2002, 277, 42943-42952.
  • 22
    • 35448949428 scopus 로고    scopus 로고
    • Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavonones in cortical neurons
    • Vauzour, D.; Vafeiadou, K.; Rice-Evans, C.: Williams, R. J.; Spencer, J. P. E. Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavonones in cortical neurons. J. Neurochem. 2007, 103, 1355-1367.
    • (2007) J. Neurochem , vol.103 , pp. 1355-1367
    • Vauzour, D.1    Vafeiadou, K.2    Rice-Evans, C.3    Williams, R.J.4    Spencer, J.P.E.5
  • 23
    • 15544368216 scopus 로고    scopus 로고
    • Store-operated calcium channels
    • Parekh, A. B.; Putney, J. W., Jr. Store-operated calcium channels. Physiol. Rev. 2005, 85, 757-810.
    • (2005) Physiol. Rev , vol.85 , pp. 757-810
    • Parekh, A.B.1    Putney Jr., J.W.2
  • 24
    • 1642464725 scopus 로고    scopus 로고
    • Genistein ameliorates β-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis
    • Zeng, H.; Chen, Q.; Zhao, B. Genistein ameliorates β-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis. Free Radical Biol. Med. 2004, 36, 180-188.
    • (2004) Free Radical Biol. Med , vol.36 , pp. 180-188
    • Zeng, H.1    Chen, Q.2    Zhao, B.3
  • 25
    • 23444445727 scopus 로고    scopus 로고
    • Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway
    • Guo, S.; Bezard, E.; Zhao, B. Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway. Free Radical Biol. Med. 2005, 39, 682-695.
    • (2005) Free Radical Biol. Med , vol.39 , pp. 682-695
    • Guo, S.1    Bezard, E.2    Zhao, B.3
  • 26
    • 0033032444 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation
    • Matsura, T.; Kai, M.; Fuji, Y.; Ito, H.; Yamada, K. Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation. Free Radical Res. 1999, 30, 73-83.
    • (1999) Free Radical Res , vol.30 , pp. 73-83
    • Matsura, T.1    Kai, M.2    Fuji, Y.3    Ito, H.4    Yamada, K.5
  • 27
    • 0032970897 scopus 로고    scopus 로고
    • Alternation of extracellular calcium elicits selective modes of cell death and protease activation in SH-SY5Y human neuroblastoma cells
    • McGinnis, K. M.; Wang, K. W. Alternation of extracellular calcium elicits selective modes of cell death and protease activation in SH-SY5Y human neuroblastoma cells. J. Neurochem. 1999, 72, 1853-1863.
    • (1999) J. Neurochem , vol.72 , pp. 1853-1863
    • McGinnis, K.M.1    Wang, K.W.2
  • 28
    • 0035104587 scopus 로고    scopus 로고
    • Caspase 3 inhibition attenuates hydrogen peroxide-induced DNA fragmentation but not cell death in neuronal PC12 cells
    • Jiang, D.; Jha, N.; Boonplueang, R.; Andersen, J. K. Caspase 3 inhibition attenuates hydrogen peroxide-induced DNA fragmentation but not cell death in neuronal PC12 cells. J. Neurochem. 2001, 76, 1745-1755.
    • (2001) J. Neurochem , vol.76 , pp. 1745-1755
    • Jiang, D.1    Jha, N.2    Boonplueang, R.3    Andersen, J.K.4
  • 30
    • 0036270446 scopus 로고    scopus 로고
    • 2+ and PI3-kinase. J. Neurochem. 2002, 80, 23-35.
    • 2+ and PI3-kinase. J. Neurochem. 2002, 80, 23-35.
  • 31
    • 0036803602 scopus 로고    scopus 로고
    • In the cellular garden of forking paths: How p38 MAPKs signal for downstream assistance
    • Shi, Y.; Gaestel, M. In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance. Biol. Chem. 2002, 383, 1519-1536.
    • (2002) Biol. Chem , vol.383 , pp. 1519-1536
    • Shi, Y.1    Gaestel, M.2
  • 35
    • 0034839145 scopus 로고    scopus 로고
    • Effect of the Alzheimer amyloid fragment Aβ(25-35) on Akt/PKB kinase and survival of PC12 cells
    • Martín, D.; Salinas, M.; López-Valdaliso, R.; Serrano, E.; Recuero, M.; Cuadrado, A. Effect of the Alzheimer amyloid fragment Aβ(25-35) on Akt/PKB kinase and survival of PC12 cells. J. Neurochem. 2001, 78, 1000-1008.
    • (2001) J. Neurochem , vol.78 , pp. 1000-1008
    • Martín, D.1    Salinas, M.2    López-Valdaliso, R.3    Serrano, E.4    Recuero, M.5    Cuadrado, A.6
  • 36
    • 33845334877 scopus 로고    scopus 로고
    • Norepinephrine induces BDNF and activates the P1-3K and MAPK cascades in embryonic hippocampal neurons
    • Chen, M. J.; Nguyen, T. V.; Pike, C. J.; Russo-Neustadt, A. A. Norepinephrine induces BDNF and activates the P1-3K and MAPK cascades in embryonic hippocampal neurons. Cell. Signalling 2007, 19, 114-128.
    • (2007) Cell. Signalling , vol.19 , pp. 114-128
    • Chen, M.J.1    Nguyen, T.V.2    Pike, C.J.3    Russo-Neustadt, A.A.4
  • 37
    • 0030842112 scopus 로고    scopus 로고
    • Relationship between flavonoid structure and inhibition of phosphatidylinosotol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition
    • Agullo, G.; Gamet-Payrastre, L.; Manenti, S.; Viala, C.; Remesy, C.; Chap, H.; Payrastre, B. Relationship between flavonoid structure and inhibition of phosphatidylinosotol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition. Biochem. Pharmacol. 1997, 53, 1649-1657.
    • (1997) Biochem. Pharmacol , vol.53 , pp. 1649-1657
    • Agullo, G.1    Gamet-Payrastre, L.2    Manenti, S.3    Viala, C.4    Remesy, C.5    Chap, H.6    Payrastre, B.7
  • 38
    • 0033634827 scopus 로고    scopus 로고
    • Structural determinants of phosphoinositide 3-kinase inhibition by wortmanin, LY294002, quercetin, myricetin, and saturosporine
    • Walker, E.: Pacold, M. E.; Perisic, O.; Stephens, L.: Hawkins, P. T.: Wymann, M. P.; Williams, R. L. Structural determinants of phosphoinositide 3-kinase inhibition by wortmanin, LY294002, quercetin, myricetin, and saturosporine. Mol. Cell 2000, 6, 909-919.
    • (2000) Mol. Cell , vol.6 , pp. 909-919
    • Walker, E.1    Pacold, M.E.2    Perisic, O.3    Stephens, L.4    Hawkins, P.T.5    Wymann, M.P.6    Williams, R.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.