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Volumn 50, Issue 1, 2014, Pages 10-18

Oxidative and antioxidative mechanisms in oral cancer and precancer: A review

Author keywords

Antioxidants; Cancer biomarkers; Enzymatic antioxidants; Free radicals; Head and neck cancer; Non enzymatic antioxidants; Oral cancer; Oral carcinogenesis; Oral precancer; Oxidants; Oxidative damage; Oxidative stress; Potentially malignant disorders; Reactive nitrogen species; Reactive oxygen species

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; CATALASE; DNA; FREE RADICAL; GLUTATHIONE; OXIDIZING AGENT; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

EID: 84890550024     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2013.09.011     Document Type: Review
Times cited : (146)

References (134)
  • 1
    • 0029439509 scopus 로고
    • Oxidative stress: The paradox of aerobic life
    • K.J. Davies Oxidative stress: the paradox of aerobic life Biochem Soc Symp 61 1995 1 31
    • (1995) Biochem Soc Symp , vol.61 , pp. 1-31
    • Davies, K.J.1
  • 2
  • 4
    • 0029824431 scopus 로고    scopus 로고
    • Antioxidants in human health and disease
    • B. Halliwell Antioxidants in human health and disease Ann Rev Nutr 16 1996 33 50 (Pubitemid 26286845)
    • (1996) Annual Review of Nutrition , vol.16 , pp. 33-50
    • Halliwell, B.1
  • 5
    • 73649149133 scopus 로고    scopus 로고
    • Status of lipid peroxidation & antioxidant enzymes in patients with carcinoma of breast
    • K.M. Surapaneni, and V.S. Chandra Sada Gopan Status of lipid peroxidation & antioxidant enzymes in patients with carcinoma of breast J Med Sci Res 1 2007 21 24
    • (2007) J Med Sci Res , vol.1 , pp. 21-24
    • Surapaneni, K.M.1    Chandra Sada Gopan, V.S.2
  • 6
    • 33947148750 scopus 로고    scopus 로고
    • Enhanced lipid peroxidation and nitric oxide products with deranged antioxidant status in patients with head and neck squamous cell carcinoma
    • DOI 10.1016/j.oraloncology.2006.02.013, PII S136883750600073X
    • M.H. Rasheed, S.S. Beevi, and G. Arumugam Enhanced lipid peroxidation and nitric oxide products with deranged antioxidant status in patients with head and neck squamous cell carcinoma Oral Oncol 43 2007 333 338 (Pubitemid 46413981)
    • (2007) Oral Oncology , vol.43 , Issue.4 , pp. 333-338
    • Rasheed, M.H.1    Beevi, S.S.2    Geetha, A.3
  • 7
    • 79961125772 scopus 로고    scopus 로고
    • Enhanced nitrosative and oxidative stress with decreased total antioxidant capacity in patients with oral precancer and oral squamous cell carcinoma
    • S.D. Korde, A. Basak, M. Chaudhary, M. Goyal, and A. Vagga Enhanced nitrosative and oxidative stress with decreased total antioxidant capacity in patients with oral precancer and oral squamous cell carcinoma Oncology 80 2011 382 389
    • (2011) Oncology , vol.80 , pp. 382-389
    • Korde, S.D.1    Basak, A.2    Chaudhary, M.3    Goyal, M.4    Vagga, A.5
  • 8
    • 0035316561 scopus 로고    scopus 로고
    • Tobacco use and oral cancer: A global perspective
    • N. Johnson Tobacco use and oral cancer: a global perspective J Dent Educ 65 4 2001 328 339
    • (2001) J Dent Educ , vol.65 , Issue.4 , pp. 328-339
    • Johnson, N.1
  • 9
    • 31844454246 scopus 로고    scopus 로고
    • Glutathione, ascorbic acid and antioxidant enzymes in the tumor tissue and blood of patients with oral squamous cell carcinoma
    • A.I. Fiaschi, A. Cozzolino, G. Ruggiero, and G. Giorgi Glutathione, ascorbic acid and antioxidant enzymes in the tumor tissue and blood of patients with oral squamous cell carcinoma Eur Rev Med Pharmacol Sci 9 2005 361 367 (Pubitemid 43180326)
    • (2005) European Review for Medical and Pharmacological Sciences , vol.9 , Issue.6 , pp. 361-367
    • Fiaschi, A.I.1    Cozzolino, A.2    Ruggiero, G.3    Giorgi, G.4
  • 10
    • 84862645136 scopus 로고    scopus 로고
    • Plasma non-enzymatic antioxidants-vitamin C, E, β-carotenes, reduced glutathione levels and total antioxidant activity in oral sub mucous fibrosis
    • K.S.C. Bose, P. Vyas, and M. Singh Plasma non-enzymatic antioxidants-vitamin C, E, β-carotenes, reduced glutathione levels and total antioxidant activity in oral sub mucous fibrosis Eur Rev Med Pharmacol Sci 16 2012 530 532
    • (2012) Eur Rev Med Pharmacol Sci , vol.16 , pp. 530-532
    • Bose, K.S.C.1    Vyas, P.2    Singh, M.3
  • 11
    • 33645999557 scopus 로고
    • Oxygen poisoning and X-ray radiation: A mechanism in common
    • R. Gerschman, D.L. Gilbert, S.W. Nye, P. Dwyer, and W.O. Fenn Oxygen poisoning and X-ray radiation: a mechanism in common Science 119 1954 623 626
    • (1954) Science , vol.119 , pp. 623-626
    • Gerschman, R.1    Gilbert, D.L.2    Nye, S.W.3    Dwyer, P.4    Fenn, W.O.5
  • 14
    • 84985570313 scopus 로고
    • Biochemistry of oxidative stress
    • H. Sies Biochemistry of oxidative stress Angew Chem Int Ed Ingl 25 12 1986 1058 1071
    • (1986) Angew Chem Int Ed Ingl , vol.25 , Issue.12 , pp. 1058-1071
    • Sies, H.1
  • 15
    • 0025987977 scopus 로고
    • Oxidative stress: From basic research to clinical application
    • H. Sies Oxidative stress: from basic research to clinical application Am J of Med 91 1991 31S 38S
    • (1991) Am J of Med , vol.91
    • Sies, H.1
  • 16
    • 0002549698 scopus 로고
    • Oxidative stress: Introductory remarks
    • H. Sies, Academic Press London
    • H. Sies Oxidative stress: introductory remarks H. Sies, Oxidative stress 1985 Academic Press London 1 8
    • (1985) Oxidative Stress , pp. 1-8
    • Sies, H.1
  • 17
    • 84890067437 scopus 로고    scopus 로고
    • Oxidative and nitrosative stresses: Their role in health and disease in man and birds
    • Volodymyr Lushchak, InTech Europe, China
    • H. Klandorf, and K.V. Dyke Oxidative and nitrosative stresses: their role in health and disease in man and birds Volodymyr Lushchak, Oxidative stress - molecular mechanisms and biological effects 2012 InTech Europe, China 47
    • (2012) Oxidative Stress - Molecular Mechanisms and Biological Effects , pp. 47
    • Klandorf, H.1    Dyke, K.V.2
  • 19
    • 32444433202 scopus 로고    scopus 로고
    • Free radicals, metals and antioxidants in oxidative stress-induced cancer
    • DOI 10.1016/j.cbi.2005.12.009, PII S0009279705004333
    • M. Valko, C.J. Rhodes, J. Moncol, M. Izakovik, and M. Mazure Free radicals, metals and antioxidants in oxidative stress-induced cancer Chemico Biol Inter 160 2006 1 40 (Pubitemid 43227479)
    • (2006) Chemico-Biological Interactions , vol.160 , Issue.1 , pp. 1-40
    • Valko, M.1    Rhodes, C.J.2    Moncol, J.3    Izakovic, M.4    Mazur, M.5
  • 20
    • 0030894162 scopus 로고    scopus 로고
    • Oxidative stress: Oxidants and antioxidants
    • H. Sies Oxidative stress: oxidants and antioxidants Exp Physiol 82 1997 291 295 (Pubitemid 27182306)
    • (1997) Experimental Physiology , vol.82 , Issue.2 , pp. 291-295
    • Sies, H.1
  • 21
    • 0027104253 scopus 로고
    • Biochemistry of nitric oxide and its redox-activated forms
    • J.S. Stamler, D. Single, and J. Loscalzo Biochemistry of nitric oxide and its redox-activated forms Science 258 1992 1898 1902 (Pubitemid 23026727)
    • (1992) Science , vol.258 , Issue.5090 , pp. 1898-1902
    • Stamler, J.S.1    Singel, D.J.2    Loscalzo, J.3
  • 23
    • 13444295358 scopus 로고    scopus 로고
    • Oxygen free radical and antioxidant defence mechanism in cancer
    • G.P. Trueba, G.M. Sánchez, and A. Giuliani Oxygen free radical and antioxidant defence mechanism in cancer Front Biosci 9 2004 2029 2044
    • (2004) Front Biosci , vol.9 , pp. 2029-2044
    • Trueba, G.P.1    Sánchez, G.M.2    Giuliani, A.3
  • 25
    • 0034719680 scopus 로고    scopus 로고
    • The transcription factor NF-κB: Control of oncogenesis and cancer therapy resistance
    • W.M. Marty, and A.S. Baldwin The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance BBA 1470 2000 M55 M62
    • (2000) BBA , vol.1470
    • Marty, W.M.1    Baldwin, A.S.2
  • 26
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death
    • M. Karin, and A. Lin NF-kappaB at the crossroads of life and death Nat Immunol 3 2002 221 227
    • (2002) Nat Immunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 28
    • 0029918901 scopus 로고    scopus 로고
    • Role of oxygen free radicals in cancer development
    • D. Dreher, and A.F. Junod Role of oxygen free radicals in cancer development Eur J Cancer 32A 1996 30 38
    • (1996) Eur J Cancer , vol.32 A , pp. 30-38
    • Dreher, D.1    Junod, A.F.2
  • 29
    • 5644272705 scopus 로고    scopus 로고
    • Invasive potential induced under long-term oxidative stress in mammary epithelial cells
    • DOI 10.1158/0008-5472.CAN-04-1725
    • K. Mori, M. Shibanuma, and K. Nose Invasive potential induced under long-term oxidative stress in mammary epithelial cells Cancer Res 64 2004 7464 7472 (Pubitemid 39372089)
    • (2004) Cancer Research , vol.64 , Issue.20 , pp. 7464-7472
    • Mori, K.1    Shibanuma, M.2    Nose, K.3
  • 30
    • 77951191817 scopus 로고    scopus 로고
    • Reactive oxygen generated by NADPH oxidase 1 (nox1) contributes to cell invasion by regulating matrix metalloprotease-9 production and cell migration
    • M. Shinohara, Y. Adachi, J. Mitsushita, M. Kuwabara, A. Nagasawa, and S. Harada Reactive oxygen generated by NADPH oxidase 1 (nox1) contributes to cell invasion by regulating matrix metalloprotease-9 production and cell migration J Biol Chem 285 2009 4481 4488
    • (2009) J Biol Chem , vol.285 , pp. 4481-4488
    • Shinohara, M.1    Adachi, Y.2    Mitsushita, J.3    Kuwabara, M.4    Nagasawa, A.5    Harada, S.6
  • 32
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients
    • J. Schmielau, and O.J. Finn Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients Cancer Res 61 2001 4756 4760 (Pubitemid 32691887)
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 33
    • 0036775442 scopus 로고    scopus 로고
    • Redox signaling of angiogenesis
    • N. Maulik Redox signaling of angiogenesis Antioxid Redox Signal 4 2002 805 815 (Pubitemid 35246944)
    • (2002) Antioxidants and Redox Signaling , vol.4 , Issue.5 , pp. 805-815
    • Maulik, N.1
  • 35
    • 61349091797 scopus 로고    scopus 로고
    • Oxidative stress in developmental origins of disease: Teratogenesis, neurodevelopmental deficits and cancer
    • P.G. Wells, G.P. McCallum, C.S. Chen, J.T. Henderson, C.J. Lee, and J. Perstin Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits and cancer Toxicol Sci 108 2009 4 18
    • (2009) Toxicol Sci , vol.108 , pp. 4-18
    • Wells, P.G.1    McCallum, G.P.2    Chen, C.S.3    Henderson, J.T.4    Lee, C.J.5    Perstin, J.6
  • 36
    • 0028927261 scopus 로고
    • Reactions of oxyl radicals with DNA
    • A.P. Breen, and J.A. Murphy Reactions of oxyl radicals with DNA Free Rad Biol Med 18 1995 1033 1077
    • (1995) Free Rad Biol Med , vol.18 , pp. 1033-1077
    • Breen, A.P.1    Murphy, J.A.2
  • 38
    • 0038799736 scopus 로고    scopus 로고
    • Oxidative DNA damage: Mechanisms, mutation, and disease
    • DOI 10.1096/fj.02-0752rev
    • M.S. Cooke, M.D. Evans, M. Dizdaroglu, and J. Lunec Oxidative DNA damage: mechanisms, mutation, and disease FASEB J 17 2003 1195 1214 (Pubitemid 36775767)
    • (2003) FASEB Journal , vol.17 , Issue.10 , pp. 1195-1214
    • Cooke, M.S.1    Evans, M.D.2    Dizdaroglu, M.3    Lunec, J.4
  • 39
    • 0030049032 scopus 로고    scopus 로고
    • Damage to DNA by reactive oxygen and nitrogen species: Role in inflammatory disease and progression to cancer
    • H. Wiseman, and B. Halliwell Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer Biochem J 313 1996 17 29 (Pubitemid 26013419)
    • (1996) Biochemical Journal , vol.313 , Issue.1 , pp. 17-29
    • Wiseman, H.1    Halliwell, B.2
  • 40
    • 0028218474 scopus 로고
    • Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis
    • DOI 10.1016/0027-5107(94)90245-3
    • H. Ohshima, and H. Bartsch Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis Mutat Res 305 1994 253 264 (Pubitemid 24082901)
    • (1994) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.305 , Issue.2 , pp. 253-264
    • Ohshima, H.1    Bartsch, H.2
  • 41
    • 0028104049 scopus 로고
    • DNA sequence changes induced by two nitric oxide donor drugs in the supF assay
    • DOI 10.1021/tx00041a007
    • M.N. Routledge, D.A. Wink, L.K. Keefer, and A. Dipple Mutations induced the by the nitric oxide generators SPER/NO and DEA/NO in the SUPF assay Chem Res Toxicol 7 1994 628 632 (Pubitemid 24302158)
    • (1994) Chemical Research in Toxicology , vol.7 , Issue.5 , pp. 628-632
    • Routledge, M.N.1    Wink, D.A.2    Keefer, L.K.3    Dipple, A.4
  • 42
    • 33847349283 scopus 로고    scopus 로고
    • Reactive oxygen species: A breath of life of death?
    • J.P. Fruehaug, and F.L. Meyskens Reactive oxygen species: a breath of life of death? Clin Cancer Res 13 2007 789 794
    • (2007) Clin Cancer Res , vol.13 , pp. 789-794
    • Fruehaug, J.P.1    Meyskens, F.L.2
  • 45
    • 31544452756 scopus 로고    scopus 로고
    • 8-Nitroguanine formation in oral leukoplakia, a premalignant lesion
    • DOI 10.1016/j.niox.2005.09.012, PII S1089860305001424
    • N. Ma, T. Tagawa, Y. Hiraku, M. Murata, X. Ding, and S. Kawanishi 8-Nitroguanine formation in oral leukoplakia, a premalignant lesion Nitric Oxide 2006 14 2006 137 143 (Pubitemid 43165879)
    • (2006) Nitric Oxide - Biology and Chemistry , vol.14 , Issue.2 SPEC. ISS. , pp. 137-143
    • Ma, N.1    Tagawa, T.2    Hiraku, Y.3    Murata, M.4    Ding, X.5    Kawanishi, S.6
  • 46
    • 33745489431 scopus 로고    scopus 로고
    • Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation related carcinogenesis
    • S. Kawanishi, Y. Hiraku, S. Pinlaor, and N. Ma Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation related carcinogenesis Biol Chem 387 2006 365 372
    • (2006) Biol Chem , vol.387 , pp. 365-372
    • Kawanishi, S.1    Hiraku, Y.2    Pinlaor, S.3    Ma, N.4
  • 47
    • 0026782895 scopus 로고
    • Deleterious mitochondrial DNA mutations accumulate in aging human tissues
    • N. Arnheim, and G. Cortopassi Deleterious mitochondrial DNA mutations accumulate in aging human tissues Mutat Res 275 1992 157 167
    • (1992) Mutat Res , vol.275 , pp. 157-167
    • Arnheim, N.1    Cortopassi, G.2
  • 48
    • 0034663470 scopus 로고    scopus 로고
    • Peroxidation of proteins before lipids in U937 cells exposed to peroxyl radicals
    • S. Gieseg, S. Duggan, and J.M. Gebicki Peroxidation of proteins before lipids in U937 cells exposed to peroxyl radicals Biochem J 350 2000 215 218
    • (2000) Biochem J , vol.350 , pp. 215-218
    • Gieseg, S.1    Duggan, S.2    Gebicki, J.M.3
  • 49
    • 4143092694 scopus 로고    scopus 로고
    • Proteins are major initial cell targets of hydroxyl free radicals
    • DOI 10.1016/j.biocel.2004.05.012, PII S135727250400202X
    • J. Du, and J.M. Gebicki Proteins are major initial cell targets of hydroxyl free radicals Int J Biochem Cell Biol 36 2004 2334 2343 (Pubitemid 39094453)
    • (2004) International Journal of Biochemistry and Cell Biology , vol.36 , Issue.11 , pp. 2334-2343
    • Du, J.1    Gebicki, J.M.2
  • 50
    • 0025674536 scopus 로고
    • Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences
    • E.R. Stadtman Metal ion-catalyzed oxidation of proteins - biochemical-mechanism and biological consequences Free Rad Biol Med 9 1990 315 325 (Pubitemid 120036900)
    • (1990) Free Radical Biology and Medicine , vol.9 , Issue.4 , pp. 315-325
    • Stadtman, E.R.1
  • 51
    • 2342518271 scopus 로고    scopus 로고
    • Role of oxidant species in aging
    • E.R. Stadtman Role of oxidant species in aging Curr Med Chem 11 2004 1105 1112 (Pubitemid 38585056)
    • (2004) Current Medicinal Chemistry , vol.11 , Issue.9 , pp. 1105-1112
    • Stadtman, E.R.1
  • 53
    • 0034545719 scopus 로고    scopus 로고
    • Quantification and significance of protein oxidation in biological samples
    • DOI 10.1081/DMR-100102336
    • E. Shacter Quantification and significance of protein oxidation in biological samples Drug Metab Rev 32 2000 307 326 (Pubitemid 32001909)
    • (2000) Drug Metabolism Reviews , vol.32 , Issue.3-4 , pp. 307-326
    • Shacter, E.1
  • 54
    • 84863316604 scopus 로고    scopus 로고
    • Serum total protein, albumin and advanced oxidation protein products (AOPP) - Implications in oral squamous cell carcinoma. Malaysian
    • A.S. Nayyar, M. Mubeen Khan, K.R. Vijayalakshmi, B. Suman, H.C. Gayitri, and M. Anitha Serum total protein, albumin and advanced oxidation protein products (AOPP) - implications in oral squamous cell carcinoma. Malaysian J Pathol 34 2012 47 52
    • (2012) J Pathol , vol.34 , pp. 47-52
    • Nayyar, A.S.1    Mubeen Khan, M.2    Vijayalakshmi, K.R.3    Suman, B.4    Gayitri, H.C.5    Anitha, M.6
  • 55
    • 84889860541 scopus 로고    scopus 로고
    • Reactive oxygen species and their relation to carcinogenesis
    • B. Grogorov Reactive oxygen species and their relation to carcinogenesis Trakia J Sci 10 2012 83 92
    • (2012) Trakia J Sci , vol.10 , pp. 83-92
    • Grogorov, B.1
  • 56
    • 0033061683 scopus 로고    scopus 로고
    • Free radicals, oxidative stress and DNA metabolism in human cancer
    • R.A. Gonzalez Free radicals, oxidative stress and DNA metabolism in human cancer Cancer Invest 17 1999 376 377
    • (1999) Cancer Invest , vol.17 , pp. 376-377
    • Gonzalez, R.A.1
  • 57
    • 0037411282 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal: A product and mediator of oxidative stress
    • DOI 10.1016/S0163-7827(03)00014-6
    • K. Uchida 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress Prog Lipid Res 42 4 2003 318 343 (Pubitemid 36411689)
    • (2003) Progress in Lipid Research , vol.42 , Issue.4 , pp. 318-343
    • Uchida, K.1
  • 58
    • 2942523593 scopus 로고    scopus 로고
    • Endogenous DNA damage in humans: A review of quantitative data
    • R.D. Bont, and N.V. Larebeke Endogenous DNA damage in humans: a review of quantitative data Mutagenesis 19 3 2004 169 185
    • (2004) Mutagenesis , vol.19 , Issue.3 , pp. 169-185
    • Bont, R.D.1    Larebeke, N.V.2
  • 59
    • 0028821342 scopus 로고
    • Induction of mutations by replication of malondialdehyde-modified M13 DNA in Escherichia coli: Determination of the extent of DNA modification, genetic requirements for mutagenesis, and types of mutations induced
    • M. Benamira, K. Johnson, A. Chaudhary, K. Bruner, C. Tibbetts, and L.J. Marnett Induction of mutations by replication of malondialdehyde-modified M13 DNA in Escherichia coli: determination of the extent of DNA modification, genetic requirements for mutagenesis, and types of mutations induced Carcinogen 16 1 1995 93 99
    • (1995) Carcinogen , vol.16 , Issue.1 , pp. 93-99
    • Benamira, M.1    Johnson, K.2    Chaudhary, A.3    Bruner, K.4    Tibbetts, C.5    Marnett, L.J.6
  • 60
    • 6044271247 scopus 로고    scopus 로고
    • Evaluation of oxidative stress and nitric oxide levels in patients with oral cavity cancer
    • DOI 10.1093/jjco/hyh058
    • S.S.S. Beevi, A.M.H. Rasheed, and A. Geetha Evaluation of oxidative stress and nitric oxide levels in patients with oral cavity cancer Jpn J Clin Oncol 34 2004 379 385 (Pubitemid 43115300)
    • (2004) Japanese Journal of Clinical Oncology , vol.34 , Issue.7 , pp. 379-385
    • Beevi, S.S.S.1    Rasheed, A.M.H.2    Geetha, A.3
  • 62
    • 0027938689 scopus 로고
    • Oxy-radicals and cancer
    • DOI 10.1016/S0140-6736(94)92832-0
    • P.A. Cerutti Oxy-radicals and cancer Lancet 344 1994 862 863 (Pubitemid 24290388)
    • (1994) Lancet , vol.344 , Issue.8926 , pp. 862-863
    • Cerutti, P.A.1
  • 64
    • 0006812769 scopus 로고
    • Potential genotoxicity of chronically elevated nitric oxide: A review
    • R.H. Li, and J.H. Hotchkiss Potential genotoxicity of chronically elevated nitric oxide: a review Mutat Res 339 1995 73 89
    • (1995) Mutat Res , vol.339 , pp. 73-89
    • Li, R.H.1    Hotchkiss, J.H.2
  • 66
    • 55249109795 scopus 로고    scopus 로고
    • Tobacco, antioxidant enzymes, oxidative stress, and genetic susceptibility in oral cancer
    • B.P. Patel, U.M. Rawal, R.M. Rawal, S.N. Shukla, and P.S. Patel Tobacco, antioxidant enzymes, oxidative stress, and genetic susceptibility in oral cancer Am J Clin Oncol 31 5 2008 454 459
    • (2008) Am J Clin Oncol , vol.31 , Issue.5 , pp. 454-459
    • Patel, B.P.1    Rawal, U.M.2    Rawal, R.M.3    Shukla, S.N.4    Patel, P.S.5
  • 67
    • 3543128313 scopus 로고    scopus 로고
    • Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: A review of agents and causative mechanisms
    • DOI 10.1093/mutage/geh036
    • U. Nair, H. Bartsch, and J. Nair Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: a review of agents and causative mechanisms Mutagen 19 4 2004 251 262 (Pubitemid 39028948)
    • (2004) Mutagenesis , vol.19 , Issue.4 , pp. 251-262
    • Nair, U.1    Bartsch, H.2    Nair, J.3
  • 68
    • 16544381591 scopus 로고    scopus 로고
    • Tobacco-related-compound-induced nitrosative stress injury in the hamster cheek pouch
    • R.D.C. Barley, S. Pollock, M.C. Shallow, E. Peters, and E.W.N. Lam Tobacco-related compound-induced nitrosative stress injury in the hamster cheek pouch J Dent Res 83 2004 903 908 (Pubitemid 41713825)
    • (2004) Journal of Dental Research , vol.83 , Issue.12 , pp. 903-908
    • Barley, R.D.C.1    Pollock, S.2    Shallow, M.C.3    Peters, E.4    Lam, E.W.N.5
  • 69
    • 0036785260 scopus 로고    scopus 로고
    • Increased expression of inducible nitric oxide synthase for human buccal squamous-cell carcinomas: Immunohistochemical, reverse transcription-polymerase chain reaction (RT-PCR) and in situ RT-PCR studies
    • Y.K. Chen, S.S. Hsue, and L.M. Lin Increased expression of inducible nitric oxide synthase for human buccal squamous-cell carcinomas: immunohistochemical, reverse transcription-polymerase chain reaction (RT-PCR) and in situ RT-PCR studies Head Neck 24 10 2002 925 932
    • (2002) Head Neck , vol.24 , Issue.10 , pp. 925-932
    • Chen, Y.K.1    Hsue, S.S.2    Lin, L.M.3
  • 70
    • 77749246399 scopus 로고    scopus 로고
    • Role of nitric oxide and antioxidant enzymes in the pathogenesis of oral cancer
    • J.B. Patel, F.D. Shah, S.N. Shukla, P.M. Shah, and P.S. Patel Role of nitric oxide and antioxidant enzymes in the pathogenesis of oral cancer JCRT 5 2009 247 253
    • (2009) JCRT , vol.5 , pp. 247-253
    • Patel, J.B.1    Shah, F.D.2    Shukla, S.N.3    Shah, P.M.4    Patel, P.S.5
  • 72
    • 10644295565 scopus 로고    scopus 로고
    • Smokeless tobacco and tobacco-related nitrosamines
    • DOI 10.1016/S1470-2045(04)01633-X, PII S147020450401633X
    • V. Cogliano, K. Straif, R. Baan, Y. Grosse, B. Secretan, and F.E.I. Ghissassi Smokeless tobacco and tobacco-related nitrosamines Lancet Oncol 5 2004 708 (Pubitemid 39646776)
    • (2004) Lancet Oncology , vol.5 , Issue.12 , pp. 708
    • Cogliano, V.1    Straif, K.2    Baan, R.3    Grosse, Y.4    Secretan, B.5    El Ghissassi, F.6
  • 74
    • 0024415449 scopus 로고
    • The involvement of reactive oxygen species in oral cancers of betel quid/tobacco chewers
    • H.F. Stitch, and F. Anders The involvement of reactive oxygen species in oral cancer of betel quid-tobacco chewers Mutat Res 214 1989 47 61 (Pubitemid 19220286)
    • (1989) Mutation Research , vol.214 , Issue.1 , pp. 47-61
    • Stich, H.F.1    Anders, F.2
  • 75
    • 1542375115 scopus 로고    scopus 로고
    • Synergistic effect of cigarette smoke and saliva on lymphocytes - The mediatory role of volatile aldehydes and redox active iron and the possible implications for oral cancer
    • DOI 10.1016/j.biocel.2003.09.003, PII S1357272503003133
    • E. Hasnis, A.Z. Reznick, S. Pollack, Y. Klein, and R.M. Nagler Synergistic effect of cigarette smoke and saliva on lymphocytes- the mediatory role of volatile aldehydes and redox active iron and the possible implications for oral cancer Int J Biochem Cell Biol 36 2004 826 839 (Pubitemid 38299398)
    • (2004) International Journal of Biochemistry and Cell Biology , vol.36 , Issue.5 , pp. 826-839
    • Hasnis, E.1    Reznick, A.Z.2    Pollack, S.3    Klein, Y.4    Nagler, R.M.5
  • 78
    • 0034955131 scopus 로고    scopus 로고
    • Role of areca nut in betel quid-associated chemical carcinogenesis: Current awareness and future perspectives
    • DOI 10.1016/S1368-8375(01)00003-3, PII S1368837501000033
    • J.H. Jeng, M.C. Chang, and L.J. Hahn Role of areca nut in betel quid associated chemical carcinogenesis: current awareness and future perspectives Oral Oncol 37 2001 477 492 (Pubitemid 32588773)
    • (2001) Oral Oncology , vol.37 , Issue.6 , pp. 477-492
    • Jeng, J.H.1    Chang, M.C.2    Hahn, L.J.3
  • 79
    • 0029394950 scopus 로고
    • Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan
    • Y.C. Ko, Y.L. Huang, C.H. Lee, M.J. Chen, L.M. Lin, and C.C. Tsai Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan J Oral Pathol Med 24 1995 450 453
    • (1995) J Oral Pathol Med , vol.24 , pp. 450-453
    • Ko, Y.C.1    Huang, Y.L.2    Lee, C.H.3    Chen, M.J.4    Lin, L.M.5    Tsai, C.C.6
  • 80
    • 16844376012 scopus 로고    scopus 로고
    • Betel-quid, and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines World Health Organization International Agency for Research on cancer. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 85, 5.5
    • Betel-quid, and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines. Summary of Data Reported and Evaluation. World Health Organization International Agency for Research on cancer. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 85, 5.5.
    • Summary of Data Reported and Evaluation
  • 82
    • 0030046535 scopus 로고    scopus 로고
    • Oxidative damage to DNA induced by areca nut extract
    • T.Y. Liu, C.L. Chen, and C.W. Chi Oxidative damage to DNA induced by areca nut extract Mutat Res 367 1996 25 31
    • (1996) Mutat Res , vol.367 , pp. 25-31
    • Liu, T.Y.1    Chen, C.L.2    Chi, C.W.3
  • 83
    • 0023271241 scopus 로고
    • Formation of reactive oxygen species and of 8-hydroxydeoxyguanosine in DNA in vitro with betal quid ingredients
    • DOI 10.1016/0009-2797(87)90095-0
    • U.J. Nair, R.A. Floyd, J. Nair, V. Bussachini, M. Friesen, and H. Bartsch Formation of reactive oxygen species and of 8-hydroxydeoxyguanosine in DNA in vitro with betel quid ingredients Chem Biol Interact 63 1987 157 169 (Pubitemid 17147600)
    • (1987) Chemico-Biological Interactions , vol.63 , Issue.2 , pp. 157-169
    • Nair, U.J.1    Floyd, R.A.2    Nair, J.3    Bussachini, V.4    Friesen, M.5    Bartsch, H.6
  • 84
    • 77955863457 scopus 로고    scopus 로고
    • Areca nut extract induced oxidative stress and upregulated hypoxia inducing factor leading to autophagy in oral cancer cells
    • H.H. Lu, S.Y. Kao, T.Y. Liu, S.T. Liu, W.P. Huang, and K.W. Chang Areca nut extract induced oxidative stress and upregulated hypoxia inducing factor leading to autophagy in oral cancer cells Autophagy 6 6 2010 725 737
    • (2010) Autophagy , vol.6 , Issue.6 , pp. 725-737
    • Lu, H.H.1    Kao, S.Y.2    Liu, T.Y.3    Liu, S.T.4    Huang, W.P.5    Chang, K.W.6
  • 85
    • 23744505520 scopus 로고    scopus 로고
    • Oral cancer: The association between nation-based alcohol-drinking profiles and oral cancer mortality
    • DOI 10.1016/j.oraloncology.2005.04.004, PII S136883750500120X
    • S. Petti, and C. Scully Oral cancer: the association between nation-based alcohol-drinking profiles and oral cancer mortality Oral Oncol 41 8 2005 828 834 (Pubitemid 41140025)
    • (2005) Oral Oncology , vol.41 , Issue.8 , pp. 828-834
    • Petti, S.1    Scully, C.2
  • 86
    • 34547118090 scopus 로고    scopus 로고
    • Molecular mechanisms of alcohol-mediated carcinogenesis
    • DOI 10.1038/nrc2191, PII NRC2191
    • H.K. Seitz, and F. Stickel Molecular mechanisms of alcohol mediated carcinogenesis Nat Rev 7 2007 599 612 (Pubitemid 47106631)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.8 , pp. 599-612
    • Seitz, H.K.1    Stickel, F.2
  • 88
    • 0027991050 scopus 로고
    • Free radicals and antioxidants: A personal view
    • B. Halliwell Free radical and antioxidants: a personal view Nutr Rev 52 1994 253 265 (Pubitemid 24308025)
    • (1994) Nutrition Reviews , vol.52 , Issue.8 , pp. 253-265
    • Halliwell, B.1
  • 89
    • 85166522701 scopus 로고
    • Vitamin e disturbances during alcohol intoxication
    • L. Packer, Fuchs Marcel Dekker New York
    • R. Nordmann, and H. Rouach Vitamin E disturbances during alcohol intoxication L. Packer, Fuchs Vitamin E in health and disease 1993 Marcel Dekker New York 935 945
    • (1993) Vitamin e in Health and Disease , pp. 935-945
    • Nordmann, R.1    Rouach, H.2
  • 90
    • 0029193185 scopus 로고
    • Antioxidants and physical performance
    • P.M. Clarkson Antioxidants and physical performance Crit Rev Food Sci Nutr 35 1995 131 141
    • (1995) Crit Rev Food Sci Nutr , vol.35 , pp. 131-141
    • Clarkson, P.M.1
  • 92
    • 0037983267 scopus 로고    scopus 로고
    • Antioxidant enzymes and human diseases
    • DOI 10.1016/S0009-9120(99)00075-2, PII S0009912099000752
    • J.M. Mates, C. Perez-Gomez, and I.N. De Castro Antioxidant enzymes and human diseases Clin Biochem 32 1999 595 603 (Pubitemid 30039087)
    • (1999) Clinical Biochemistry , vol.32 , Issue.8 , pp. 595-603
    • Mates, J.M.1    Perez-Gomez, C.2    De Castro, I.N.3
  • 93
    • 0043197852 scopus 로고    scopus 로고
    • Intracellular antioxidants: From chemical to biochemical mechanisms
    • DOI 10.1016/S0278-6915(99)00090-3, PII S0278691599000903
    • J. Chaudière, and R. Ferrari-Iliou Intracellular Antioxidants: from chemical to biochemical mechanisms Food Chem Toxicol 37 1999 949 962 (Pubitemid 29481797)
    • (1999) Food and Chemical Toxicology , vol.37 , Issue.9-10 , pp. 949-962
    • Chaudiere, J.1    Ferrari-Iliou, R.2
  • 94
    • 0004863828 scopus 로고    scopus 로고
    • Inhibition of copper-induced LDL oxidation by vitamin C is associated with decreased copper-binding to LDL and 2-oxo-histidine formation
    • DOI 10.1016/S0891-5849(98)00151-8, PII S0891584998001518
    • K.L. Retsky, K. Chen, J. Zeind, and B. Frei Inhibition of copper induced LDL oxidation by Vitamin C is associated with decreased copper-binding to LDL and 2-oxo-histidine formation Free Rad Biol Med 26 1999 90 98 (Pubitemid 29001496)
    • (1998) Free Radical Biology and Medicine , vol.26 , Issue.1-2 , pp. 90-98
    • Retsky, K.L.1    Chen, K.2    Zeind, J.3    Frei, B.4
  • 96
    • 0033983165 scopus 로고    scopus 로고
    • Vitamin E and heart disease: Basic science to clinical intervention trials
    • DOI 10.1016/S0891-5849(99)00224-5, PII S0891584999002245
    • W.A. Pryor VitaminE and heart disease: basic science to clinical intervention trials Free Rad Biol Med 28 2000 141 164 (Pubitemid 30045582)
    • (2000) Free Radical Biology and Medicine , vol.28 , Issue.1 , pp. 141-164
    • Pryor, W.A.1
  • 98
    • 84866179913 scopus 로고    scopus 로고
    • Does Vitamin e prevent or promote cancer?
    • C.S. Yang, N. Suh, and A.N. Kong Does Vitamin E prevent or promote cancer? Cancer Prev Res 5 5 2012 701 705
    • (2012) Cancer Prev Res , vol.5 , Issue.5 , pp. 701-705
    • Yang, C.S.1    Suh, N.2    Kong, A.N.3
  • 100
    • 67449158983 scopus 로고    scopus 로고
    • Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-g
    • H.J. Lee, J. Ju, S. Paul, J.Y. So, A. DeCastro, and A.K. Smolarek Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-g Clin Cancer Res 15 2009 4242 4249
    • (2009) Clin Cancer Res , vol.15 , pp. 4242-4249
    • Lee, H.J.1    Ju, J.2    Paul, S.3    So, J.Y.4    Decastro, A.5    Smolarek, A.K.6
  • 101
    • 25144482448 scopus 로고    scopus 로고
    • Novel mechanisms of natural antioxidant compounds in biological systems: Involvement of glutathione and glutathione-related enzymes
    • DOI 10.1016/j.jnutbio.2005.05.013, PII S095528630500152X
    • R. Masella, R. Di Benedetto, R. Vari, C. Filesi, and C. Giovannini Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes J Nutr Biochem 16 2005 577 586 (Pubitemid 41338369)
    • (2005) Journal of Nutritional Biochemistry , vol.16 , Issue.10 , pp. 577-586
    • Masella, R.1    Di Benedetto, R.2    Vari, R.3    Filesi, C.4    Giovannini, C.5
  • 102
    • 0026043122 scopus 로고
    • Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer
    • S. De Flora, A. Izzotti, F. D'Agostini, and C.F. Cesarone Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer Am J Med 91 3C 1991 122S 130S
    • (1991) Am J Med , vol.91 , Issue.3 C
    • De Flora, S.1    Izzotti, A.2    D'Agostini, F.3    Cesarone, C.F.4
  • 103
    • 34548066349 scopus 로고    scopus 로고
    • Thiols and the chemoprevention of cancer
    • DOI 10.1016/j.coph.2007.05.005, PII S1471489207000987, Cancer/Immunomodulation
    • W.W. Huber, and W. Parzefall Thiols and the chemoprevention of cancer Curr Opin Pharmacol 7 4 2007 404 409 (Pubitemid 47289264)
    • (2007) Current Opinion in Pharmacology , vol.7 , Issue.4 , pp. 404-409
    • Huber, W.W.1    Parzefall, W.2
  • 104
    • 36248980349 scopus 로고    scopus 로고
    • Lipid peroxidation, total antioxidant status, and total thiol levels predict overall survival in patients with oral squamous cell carcinoma
    • DOI 10.1177/1534735407309760
    • B.P. Patel, U.M. Rawal, T.K. Dave, R.M. Rawal, S.N. Shukla, and P.M. Shah Lipid peroxidation, total antioxidant status, and total thiol levels predict overall survival in patients with oral squamous cell carcinoma Integr Cancer Ther 6 4 2007 365 372 (Pubitemid 350136020)
    • (2007) Integrative Cancer Therapies , vol.6 , Issue.4 , pp. 365-372
    • Patel, B.P.1    Rawal, U.M.2    Dave, T.K.3    Rawal, R.M.4    Shukla, S.N.5    Shah, P.M.6    Patel, P.S.7
  • 105
    • 0142216401 scopus 로고    scopus 로고
    • Antioxidant activity of carotenoids
    • DOI 10.1016/S0098-2997(03)00030-X
    • W. Stahl, and H. Sies Antioxidant activity of carotenoids Mol Aspects Med 24 6 2003 345 351 (Pubitemid 37324647)
    • (2003) Molecular Aspects of Medicine , vol.24 , Issue.6 , pp. 345-351
    • Stahl, W.1    Sies, H.2
  • 107
    • 38449121513 scopus 로고    scopus 로고
    • Studies on free radicals, antioxidants, and co-factors
    • K. Rahman Studies on free radicals, antioxidants, and co-factors Clin Interv Aging 2 2 2007 219 236
    • (2007) Clin Interv Aging , vol.2 , Issue.2 , pp. 219-236
    • Rahman, K.1
  • 108
    • 77953408636 scopus 로고    scopus 로고
    • The antioxidant phytochemicals of nutraceutical importance
    • D. Prakash, and K.R. Gupta The antioxidant phytochemicals of nutraceutical importance Open Nutraceuticals J 2 2009 20 35
    • (2009) Open Nutraceuticals J , vol.2 , pp. 20-35
    • Prakash, D.1    Gupta, K.R.2
  • 109
    • 0344943236 scopus 로고    scopus 로고
    • Garlic and aging: New insights into an old remedy
    • DOI 10.1016/S1568-1637(02)00049-1, PII S1568163702000491
    • K. Rahman Garlic and aging: new insights into an old remedy Ageing Res Rev 2 2003 39 56 (Pubitemid 37443917)
    • (2003) Ageing Research Reviews , vol.2 , Issue.1 , pp. 39-56
    • Rahman, K.1
  • 110
    • 33747866718 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-κB signaling in human epidermal keratinocytes
    • DOI 10.1016/j.freeradbiomed.2005.12.032, PII S0891584906000050
    • S.K. Mantena, and S.K. Katiyar Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-kB signalling in human epidermal keratinocytes Free Radic Biol Med 40 2006 1603 1614 (Pubitemid 44316663)
    • (2006) Free Radical Biology and Medicine , vol.40 , Issue.9 , pp. 1603-1614
    • Mantena, S.K.1    Katiyar, S.K.2
  • 111
    • 0002326107 scopus 로고
    • Non enzymatic antioxidant defense systems
    • B. Frie, Academic press Inc. San Diego (CA)
    • K. Briviba, and H. Sies Non enzymatic antioxidant defense systems B. Frie, Natural antioxidants in human health and diseases 1994 Academic press Inc. San Diego (CA) 119 121
    • (1994) Natural Antioxidants in Human Health and Diseases , pp. 119-121
    • Briviba, K.1    Sies, H.2
  • 112
    • 0028864835 scopus 로고
    • Vitamins e and C, beta-carotene, and other carotenoids as antioxidants
    • H. Sies, and W. Stahl Vitamins E and C, beta-carotene, and other carotenoids as antioxidants Am J Clin Nutr 62 6 Suppl 1995 1315S 1321S
    • (1995) Am J Clin Nutr , vol.62 , Issue.6 SUPPL.
    • Sies, H.1    Stahl, W.2
  • 113
    • 0346366555 scopus 로고    scopus 로고
    • Evidence of oxidative stress in the circulation of ovarian cancer patients
    • DOI 10.1016/j.cccn.2003.08.017
    • K. Senthil, S. Aranganathan, and N. Nalini Evidence of oxidative stress in the circulation of ovarian cancer patients Clin Chim Acta 339 1-2 2004 27 32 (Pubitemid 37542454)
    • (2004) Clinica Chimica Acta , vol.339 , Issue.1-2 , pp. 27-32
    • Senthil, K.1    Aranganathan, S.2    Nalini, N.3
  • 114
    • 65649100524 scopus 로고    scopus 로고
    • Elevated levels of oxidative stress markers in exhaled breath condensate
    • H.P. Chan, V. Tran, C. Lewis, and P.S. Thomas Elevated levels of oxidative stress markers in exhaled breath condensate J Thorac Oncol 4 2 2009 172 178
    • (2009) J Thorac Oncol , vol.4 , Issue.2 , pp. 172-178
    • Chan, H.P.1    Tran, V.2    Lewis, C.3    Thomas, P.S.4
  • 115
    • 0033841567 scopus 로고    scopus 로고
    • Serum antioxidant micronutrients and the risk of oral leukoplakia among Japanese
    • DOI 10.1016/S1368-8375(00)00037-3, PII S1368837500000373
    • T. Nagao, N. Ikeda, S. Warnakulasuriya, H. Fukano, H. Yuasa, and M. Yano Serum antioxidant micronutrients and the risk of oral leukoplakia among Japanese Oral Oncol 36 2000 466 470 (Pubitemid 30645983)
    • (2000) Oral Oncology , vol.36 , Issue.5 , pp. 466-470
    • Nagao, T.1    Ikeda, N.2    Warnakulasuriya, S.3    Fukano, H.4    Yuasa, H.5    Yano, M.6    Miyazaki, H.7    Ito, Y.8
  • 116
    • 84857221141 scopus 로고    scopus 로고
    • Antitumor activity of antioxidants - An overview
    • M.K. Jawanda Antitumor activity of antioxidants - an overview Int J Dental Clin 1 1 2009 3 7
    • (2009) Int J Dental Clin , vol.1 , Issue.1 , pp. 3-7
    • Jawanda, M.K.1
  • 117
    • 0031945243 scopus 로고    scopus 로고
    • Mechanisms of cancer inhibition by anti-oxidant nutrients
    • DOI 10.1016/S1368-8375(97)00060-2, PII S1368837597000602
    • G. Shklar Mechanisms of cancer inhibition by anti-oxidant nutrients Oral Oncol 34 1 1998 24 29 (Pubitemid 28210527)
    • (1998) Oral Oncology , vol.34 , Issue.1 , pp. 24-29
    • Shklar, G.1
  • 119
    • 0025971220 scopus 로고
    • Sequential mast cell infiltration and degranulation during experimental carcinogenesis
    • E. Flynn, J. Schwartz, and G. Shklar Sequential mast cell infiltration and degranulation during experimental carcinogenesis J Cancer Res Clin Oncol 117 2 1991 115 122
    • (1991) J Cancer Res Clin Oncol , vol.117 , Issue.2 , pp. 115-122
    • Flynn, E.1    Schwartz, J.2    Shklar, G.3
  • 120
    • 0021928445 scopus 로고
    • Alpha tocopherol alters the distribution of Langerhans cells in DMBA-treated hamster cheek pouch epithelium
    • J. Schwartz, O. Odukoya, E. Stoufi, and G. Shklar Alpha ocopherol alters the distribution of Langerhans cells in DMBA-treated hamster cheek pouch epithelium J Dent Res 64 2 1985 117 121 (Pubitemid 15102865)
    • (1985) Journal of Dental Research , vol.64 , Issue.2 , pp. 117-121
    • Schwartz, J.1    Odukoya, O.2    Stoufi, E.3    Shklar, G.4
  • 121
    • 0020957654 scopus 로고
    • Role of retinoids in differentiation and carcinogenesis
    • M.B. Sporn, and A.B. Roberts Role of retinoids in differentiation and carcinogenesis Cancer Res 43 7 1983 3034 3040 (Pubitemid 13061542)
    • (1983) Cancer Research , vol.43 , Issue.7 , pp. 3034-3040
    • Sporn, M.B.1    Roberts, A.B.2
  • 122
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: Preclinical and clinical studies
    • B.B. Aggarwal, A. Kumar, and A.C. Bharti Anticancer potential of curcumin: preclinical and clinical studies Anticancer Res 2003 23 2003 363 398 (Pubitemid 36361976)
    • (2003) Anticancer Research , vol.23 , Issue.1 A , pp. 363-398
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 123
    • 33749633974 scopus 로고    scopus 로고
    • Curcumin down regulates smokeless tobacco-induced NF-κB activation and COX-2 expression in human oral premalignant and cancer cells
    • DOI 10.1016/j.tox.2006.07.027, PII S0300483X06004938
    • C. Sharma, J. Kaur, S. Shishodia, B.B. Aggarwal, and R. Ralhan Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells Toxicol 228 2006 1 15 (Pubitemid 44548099)
    • (2006) Toxicology , vol.228 , Issue.1 , pp. 1-15
    • Sharma, C.1    Kaur, J.2    Shishodia, S.3    Aggarwal, B.B.4    Ralhan, R.5
  • 124
    • 79952496272 scopus 로고    scopus 로고
    • Possible action mechanism for curcumin in pre cancerous lesions based on serum and salivary markers of oxidative stress
    • B. Rai, J. Kaur, R. Jacobs, and J. Singh Possible action mechanism for curcumin in pre cancerous lesions based on serum and salivary markers of oxidative stress J Oral Sci 52 2 2010 251 256
    • (2010) J Oral Sci , vol.52 , Issue.2 , pp. 251-256
    • Rai, B.1    Kaur, J.2    Jacobs, R.3    Singh, J.4
  • 125
    • 0031753927 scopus 로고    scopus 로고
    • Dietary factors in oral leukoplakia and submucous fibrosis in a population-based case control study in Gujarat, India
    • P.C. Gupta, J.R. Hebert, R.B. Bhonsle, P.N. Sinor, H. Mehta, and F.S. Mehta Dietary factors in oral leukoplakia and submucous fibrosis in a population-based case control study in Gujarat, India Oral Dis 4 1998 200 206 (Pubitemid 28427804)
    • (1998) Oral Diseases , vol.4 , Issue.3 , pp. 200-206
    • Gupta, P.C.1    Hebert, J.R.2    Bhonsle, R.B.3    Sinor, P.N.4    Mehta, H.5    Mehta, F.S.6
  • 126
    • 0031022376 scopus 로고    scopus 로고
    • Evaluation of multiple micronutrient supplementation in the management of oral submucous fibrosis in Karachi, Pakistan
    • R. Maher, P. Aga, N.W. Johnson, R. Sankaranarayanan, and S. Warnakulasuriya Evaluation of multiple micronutrient supplementation in the management of oral submucous fibrosis in Karachi, Pakistan Nutr Cancer 27 1997 41 47 (Pubitemid 26424314)
    • (1997) Nutrition and Cancer , vol.27 , Issue.1 , pp. 41-47
    • Maher, R.1    Aga, P.2    Johnson, N.W.3    Sankaranarayanan, R.4    Warnakulasuriya, S.5
  • 127
    • 79953701022 scopus 로고    scopus 로고
    • Modulatory action of α-tocopherol on erythrocyte membrane adenosine triphosphatase against radiation damage in oral cancer
    • S. Chitra, and C.S. Shyamaladevi Modulatory action of α-tocopherol on erythrocyte membrane adenosine triphosphatase against radiation damage in oral cancer J Membr Biol 240 2 2011 83 88
    • (2011) J Membr Biol , vol.240 , Issue.2 , pp. 83-88
    • Chitra, S.1    Shyamaladevi, C.S.2
  • 129
    • 80051771739 scopus 로고    scopus 로고
    • The response of oral submucous fibrosis to lycopene - A carotenoid antioxidant: A clinicopathological study
    • B.B.K. Gowda, T.R. Yathish, S. Sankappa, H. Kumar Naik, P. Somayaji, and D. Anand The response of oral submucous fibrosis to lycopene - a carotenoid antioxidant: a clinicopathological study JCDR 5 2011 882 888
    • (2011) JCDR , vol.5 , pp. 882-888
    • Gowda, B.B.K.1    Yathish, T.R.2    Sankappa, S.3    Kumar Naik, H.4    Somayaji, P.5    Anand, D.6
  • 130
    • 1842424987 scopus 로고    scopus 로고
    • Efficacy of oral lycopene in the treatment of oral leukoplakia
    • DOI 10.1016/j.oraloncology.2003.12.011, PII S1368837503002811
    • M. Singh, R. Krishanappa, A. Bagewadi, and V. Keluskar Efficacy of oral lycopene in the treatment of oral leukoplakia Oral Oncol 40 2004 591 596 (Pubitemid 38452678)
    • (2004) Oral Oncology , vol.40 , Issue.6 , pp. 591-596
    • Singh, M.1    Krishanappa, R.2    Bagewadi, A.3    Keluskar, V.4
  • 131
    • 0036846616 scopus 로고    scopus 로고
    • Overview of mechanisms of action of lycopene
    • D. Heber, and Q.Y. Lu Overview of mechanisms of action of lycopene Exp Biol Med (Maywood) 227 2002 920 923 (Pubitemid 35340348)
    • (2002) Experimental Biology and Medicine , vol.227 , Issue.10 , pp. 920-923
    • Heber, D.1    Lu, Q.-Y.2
  • 132
    • 0027399363 scopus 로고
    • Oral cancer inhibition by micronutrients. The experimental basis for clinical trials
    • DOI 10.1016/0964-1955(93)90004-X
    • G. Shklar, and J. Schwartz Oral cancer inhibition by micronutrients. The experimental basis for clinical trials Eur J Cancer B Oral Oncol 29 B 1 1993 9 16 (Pubitemid 23068390)
    • (1993) European Journal of Cancer Part B: Oral Oncology , vol.29 , Issue.1 , pp. 9-16
    • Shklar, G.1    Schwartz, J.2
  • 133
    • 33747880513 scopus 로고    scopus 로고
    • Enzymatic and non-enzymatic antioxidant status in stage (III) human oral squamous cell carcinoma and treated with radical radio therapy: Influence of selenium supplementation
    • DOI 10.1016/j.cca.2006.05.021, PII S0009898106002658
    • N. Elango, S. Samuel, and P. Chinnakkannu Enzymatic and non-enzymatic antioxidant status in stage (III) human oral squamous cell carcinoma and treated with radical radio therapy: Influence of selenium supplementation Clin Chim Acta 373 1-2 2006 92 98 (Pubitemid 44292181)
    • (2006) Clinica Chimica Acta , vol.373 , Issue.1-2 , pp. 92-98
    • Elango, N.1    Samuel, S.2    Chinnakkannu, P.3
  • 134
    • 70349280735 scopus 로고    scopus 로고
    • Effect of oral antioxidant supplementation on lipid peroxidation during radiotherapy in head and neck malignancies
    • A.K. Shariff, S.R. Patil, P.S. Shukla, A.V. Sontakke, A.S. Hendre, and A.K. Gudur Effect of oral antioxidant supplementation on lipid peroxidation during radiotherapy in head and neck malignancies Indian J Clin Biochem 24 2009 307 331
    • (2009) Indian J Clin Biochem , vol.24 , pp. 307-331
    • Shariff, A.K.1    Patil, S.R.2    Shukla, P.S.3    Sontakke, A.V.4    Hendre, A.S.5    Gudur, A.K.6


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