-
1
-
-
0347504835
-
TRP channels as cellular sensors
-
Clapham, D. E. (2003) TRP channels as cellular sensors. Nature 426, 517-524
-
(2003)
Nature
, vol.426
, pp. 517-524
-
-
Clapham, D.E.1
-
2
-
-
59649113294
-
Physiology and pathophysiology of canonical transient receptor potential channels
-
Abramowitz, J., and Birnbaumer, L. (2009) Physiology and pathophysiology of canonical transient receptor potential channels. FASEB J. 23, 297-328
-
(2009)
FASEB J.
, vol.23
, pp. 297-328
-
-
Abramowitz, J.1
Birnbaumer, L.2
-
3
-
-
80052410575
-
Reactive oxygen species-mediated TRPC6 activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone
-
Ding, Y., Winters, A., Ding, M., Graham, S., Akopova, I., Muallem, S., Wang, Y., Hong, J. H., Gryczynski, Z., Yang, S. H., Birnbaumer, L., and Ma, R. (2011) Reactive oxygen species-mediated TRPC6 activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone. J. Biol. Chem. 286, 31799-31809
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 31799-31809
-
-
Ding, Y.1
Winters, A.2
Ding, M.3
Graham, S.4
Akopova, I.5
Muallem, S.6
Wang, Y.7
Hong, J.H.8
Gryczynski, Z.9
Yang, S.H.10
Birnbaumer, L.11
Ma, R.12
-
5
-
-
79960991150
-
Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes
-
Graham, S., Gorin, Y., Abboud, H. E., Ding, M., Lee, D. Y., Shi, H., Ding, Y., and Ma, R. (2011) Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes. Am. J. Physiol. Cell Physiol. 301, C304-C315
-
(2011)
Am. J. Physiol. Cell Physiol.
, vol.301
-
-
Graham, S.1
Gorin, Y.2
Abboud, H.E.3
Ding, M.4
Lee, D.Y.5
Shi, H.6
Ding, Y.7
Ma, R.8
-
6
-
-
66349095797
-
A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension
-
Yu, Y., Keller, S. H., Remillard, C. V., Safrina, O., Nicholson, A., Zhang, S. L., Jiang, W., Vangala, N., Landsberg, J. W., Wang, J. Y., Thistlethwaite, P. A., Channick, R. N., Robbins, I. M., Loyd, J. E., Ghofrani, H. A., Grimminger, F., Schermuly, R. T., Cahalan, M. D., Rubin, L. J., and Yuan, J. X. (2009) A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension. Circulation 119, 2313-2322
-
(2009)
Circulation
, vol.119
, pp. 2313-2322
-
-
Yu, Y.1
Keller, S.H.2
Remillard, C.V.3
Safrina, O.4
Nicholson, A.5
Zhang, S.L.6
Jiang, W.7
Vangala, N.8
Landsberg, J.W.9
Wang, J.Y.10
Thistlethwaite, P.A.11
Channick, R.N.12
Robbins, I.M.13
Loyd, J.E.14
Ghofrani, H.A.15
Grimminger, F.16
Schermuly, R.T.17
Cahalan, M.D.18
Rubin, L.J.19
Yuan, J.X.20
more..
-
7
-
-
4644290321
-
Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension
-
DOI 10.1073/pnas.0405908101
-
Yu, Y., Fantozzi, I., Remillard, C. V., Landsberg, J. W., Kunichika, N., Platoshyn, O., Tigno, D. D., Thistlethwaite, P. A., Rubin, L. J., and Yuan, J. X. (2004) Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Proc. Natl. Acad. Sci. U.S.A. 101, 13861-13866 (Pubitemid 39298498)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.38
, pp. 13861-13866
-
-
Yu, Y.1
Fantozzi, I.2
Remillard, C.V.3
Landsberg, J.W.4
Kunichika, N.5
Platoshyn, O.6
Tigno, D.D.7
Thistlethwaite, P.A.8
Rubin, L.J.9
Yuan, J.X.-J.10
-
8
-
-
20844461826
-
Medicine: A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis
-
DOI 10.1126/science.1106215
-
Winn, M. P., Conlon, P. J., Lynn, K. L., Farrington, M. K., Creazzo, T., Hawkins, A. F., Daskalakis, N., Kwan, S. Y., Ebersviller, S., Burchette, J. L., Pericak-Vance, M. A., Howell, D. N., Vance, J. M., and Rosenberg, P. B. (2005) A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science 308, 1801-1804 (Pubitemid 40848011)
-
(2005)
Science
, vol.308
, Issue.5729
, pp. 1801-1804
-
-
Winn, M.P.1
Conlon, P.J.2
Lynn, K.L.3
Farrington, M.K.4
Creazzo, T.5
Hawkins, A.F.6
Daskalakis, N.7
Kwan, S.Y.8
Ebersviller, S.9
Burchette, J.L.10
Pericak-Vance, M.A.11
Howell, D.N.12
Vance, J.M.13
Rosenberg, P.B.14
-
9
-
-
33645461305
-
Unexpected role of TRPC6 channel in familial nephrotic syndrome. Does it have clinical implications?
-
Winn, M. P., Daskalakis, N., Spurney, R. F., and Middleton, J. P. (2006) Unexpected role of TRPC6 channel in familial nephrotic syndrome. Does it have clinical implications? J. Am. Soc. Nephrol. 17, 378-387
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 378-387
-
-
Winn, M.P.1
Daskalakis, N.2
Spurney, R.F.3
Middleton, J.P.4
-
10
-
-
33751104984
-
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy
-
DOI 10.1038/sj.emboj.7601417, PII 7601417
-
Onohara, N., Nishida, M., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., and Kurose, H. (2006) TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. EMBO J. 25, 5305-5316 (Pubitemid 44764140)
-
(2006)
EMBO Journal
, vol.25
, Issue.22
, pp. 5305-5316
-
-
Onohara, N.1
Nishida, M.2
Inoue, R.3
Kobayashi, H.4
Sumimoto, H.5
Sato, Y.6
Mori, Y.7
Nagao, T.8
Kurose, H.9
-
11
-
-
2542484361
-
Activation of human TRPC6 channels by receptor stimulation
-
DOI 10.1074/jbc.M402320200
-
Estacion, M., Li, S., Sinkins, W. G., Gosling, M., Bahra, P., Poll, C., Westwick, J., and Schilling, W. P. (2004) Activation of human TRPC6 channels by receptor stimulation. J. Biol. Chem. 279, 22047-22056 (Pubitemid 38679396)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.21
, pp. 22047-22056
-
-
Estacion, M.1
Li, S.2
Sinkins, W.G.3
Gosling, M.4
Bahra, P.5
Poll, C.6
Westwick, J.7
Schilling, W.P.8
-
12
-
-
0033593577
-
Molecular cloning and characterization of rat trp homologues from brain
-
Mizuno, N. (1999) Molecular cloning and characterization of rat trp homologues from brain. Brain Res. Mol. Brain Res. 64, 41-51
-
(1999)
Brain Res. Mol. Brain Res.
, vol.64
, pp. 41-51
-
-
Mizuno, N.1
-
13
-
-
0033590450
-
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
-
Hofmann, T., Obukhov, A. G., Schaefer, M., Harteneck, C., Gudermann, T., and Schultz, G. (1999) Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397, 259-263
-
(1999)
Nature
, vol.397
, pp. 259-263
-
-
Hofmann, T.1
Obukhov, A.G.2
Schaefer, M.3
Harteneck, C.4
Gudermann, T.5
Schultz, G.6
-
14
-
-
77954914431
-
Canonical transient receptor potential 6 (TRPC6), a redox-regulated cation channel
-
Graham, S., Ding, M., Ding, Y., Sours-Brothers, S., Luchowski, R., Gryczynski, Z., Yorio, T., Ma, H., and Ma, R. (2010) Canonical transient receptor potential 6 (TRPC6), a redox-regulated cation channel. J. Biol. Chem. 285, 23466-23476
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 23466-23476
-
-
Graham, S.1
Ding, M.2
Ding, Y.3
Sours-Brothers, S.4
Luchowski, R.5
Gryczynski, Z.6
Yorio, T.7
Ma, H.8
Ma, R.9
-
15
-
-
84856692677
-
Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice
-
Weissmann, N., Sydykov, A., Kalwa, H., Storch, U., Fuchs, B., Mederos y Schnitzler, M., Brandes, R. P., Grimminger, F., Meissner, M., Freichel, M., Offermanns, S., Veit, F., Pak, O., Krause, K. H., Schermuly, R. T., Brewer, A. C., Schmidt, H. H., Seeger, W., Shah, A. M., Gudermann, T., Ghofrani, H. A., and Dietrich, A. (2012) Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice. Nat. Commun. 3, 649
-
(2012)
Nat. Commun.
, vol.3
, pp. 649
-
-
Weissmann, N.1
Sydykov, A.2
Kalwa, H.3
Storch, U.4
Fuchs, B.5
Mederos Schnitzler, M.6
Brandes, R.P.7
Grimminger, F.8
Meissner, M.9
Freichel, M.10
Offermanns, S.11
Veit, F.12
Pak, O.13
Krause, K.H.14
Schermuly, R.T.15
Brewer, A.C.16
Schmidt, H.H.17
Seeger, W.18
Shah, A.M.19
Gudermann, T.20
Ghofrani, H.A.21
Dietrich, A.22
more..
-
16
-
-
79957581524
-
cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase (MEK)-ERK1/2 signaling pathway
-
Shen, B., Kwan, H. Y., Ma, X., Wong, C. O., Du, J., Huang, Y., and Yao, X. (2011) cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase (MEK)-ERK1/2 signaling pathway. J. Biol. Chem. 286, 19439-19445
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 19439-19445
-
-
Shen, B.1
Kwan, H.Y.2
Ma, X.3
Wong, C.O.4
Du, J.5
Huang, Y.6
Yao, X.7
-
17
-
-
84861219840
-
Involvement of phosphoinositide 3-kinase andPTENin the mechanism of activation of TRPC6 in vascular smooth muscle cells
-
Monet, M., Francoeur, N., and Boulay, G. (2012) Involvement of phosphoinositide 3-kinase andPTENin the mechanism of activation of TRPC6 in vascular smooth muscle cells. J. Biol. Chem. 287, 17672-17681
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 17672-17681
-
-
Monet, M.1
Francoeur, N.2
Boulay, G.3
-
18
-
-
78650355289
-
Protein kinase C-dependent phosphorylation of transient receptor potential canonical 6 (TRPC6) on serine 448 causes channel inhibition
-
Bousquet, S. M., Monet, M., and Boulay, G. (2010) Protein kinase C-dependent phosphorylation of transient receptor potential canonical 6 (TRPC6) on serine 448 causes channel inhibition. J. Biol. Chem. 285, 40534-40543
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40534-40543
-
-
Bousquet, S.M.1
Monet, M.2
Boulay, G.3
-
20
-
-
33845991537
-
Oxidants in chronic kidney disease
-
DOI 10.1681/ASN.2006050500
-
Shah, S. V., Baliga, R., Rajapurkar, M., and Fonseca, V. A. (2007) Oxidants in chronic kidney disease. J. Am. Soc. Nephrol. 18, 16-28 (Pubitemid 46053418)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.1
, pp. 16-28
-
-
Shah, S.V.1
Baliga, R.2
Rajapurkar, M.3
Fonseca, V.A.4
-
21
-
-
34250338918
-
Redox imbalance in diabetes
-
DOI 10.1089/ars.2007.1640
-
Hayden, M. R., and Sowers, J. R. (2007) Redox imbalance in diabetes. Antioxid. Redox. Signal. 9, 865-867 (Pubitemid 46919589)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.7
, pp. 865-867
-
-
Hayden, M.R.1
Sowers, J.R.2
-
22
-
-
34248209629
-
Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-κB and protein kinase C
-
DOI 10.1681/ASN.2006121373
-
Banday, A. A., Fazili, F. R., and Lokhandwala, M. F. (2007) Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-kB and protein kinase C. J. Am. Soc. Nephrol. 18, 1446-1457 (Pubitemid 46717511)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.5
, pp. 1446-1457
-
-
Banday, A.A.1
Fazili, F.R.2
Lokhandwala, M.F.3
-
23
-
-
34250346114
-
Oxidant stress, immune dysregulation, and vascular function in type I diabetes
-
DOI 10.1089/ars.2007.1631
-
Nicolls, M. R., Haskins, K., and Flores, S. C. (2007) Oxidant stress, immune dysregulation, and vascular function in type 1 diabetes. Antioxid. Redox. Signal. 9, 879-889 (Pubitemid 46919591)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.7
, pp. 879-889
-
-
Nicolls, M.R.1
Haskins, K.2
Flores, S.C.3
-
24
-
-
84859844692
-
Mesangial cell biology
-
Abboud, H. E. (2012) Mesangial cell biology. Exp. Cell Res. 318, 979-985
-
(2012)
Exp. Cell Res.
, vol.318
, pp. 979-985
-
-
Abboud, H.E.1
-
25
-
-
0342466799
-
Glomerular mesangial cells: Electrophysiology and regulation of contraction
-
Stockand, J. D., and Sansom, S. C. (1998) Glomerular mesangial cells. Electrophysiology and regulation of contraction. Physiol. Rev. 78, 723-744 (Pubitemid 28340601)
-
(1998)
Physiological Reviews
, vol.78
, Issue.3
, pp. 723-744
-
-
Stockand, J.D.1
Sansom, S.C.2
-
26
-
-
67449083682
-
The mesangial cell revisited. No cell is an island
-
Schlöndorff, D., and Banas, B. (2009) The mesangial cell revisited. No cell is an island. J. Am. Soc. Nephrol. 20, 1179-1187
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 1179-1187
-
-
Schlöndorff, D.1
Banas, B.2
-
27
-
-
0026587840
-
The pathobiology of the mesangium
-
Kashgarian, M., and Sterzel, R. B. (1992) The pathobiology of the mesangium. Kidney Int. 41, 524-529
-
(1992)
Kidney Int.
, vol.41
, pp. 524-529
-
-
Kashgarian, M.1
Sterzel, R.B.2
-
28
-
-
27544483644
-
Cell biology of diabetic kidney disease
-
DOI 10.1159/000087339
-
Kanwar, Y. S., Akagi, S., Sun, L., Nayak, B., Xie, P., Wada, J., Chugh, S. S., and Danesh, F. R. (2005) Cell biology of diabetic kidney disease. Nephron. Exp. Nephrol. 101, e100-e110 (Pubitemid 41540698)
-
(2005)
Nephron - Experimental Nephrology
, vol.101
, Issue.3
-
-
Kanwar, Y.S.1
Akagi, S.2
Sun, L.3
Nayak, B.4
Xie, P.5
Wada, J.6
Chugh, S.S.7
Danesh, F.R.8
-
29
-
-
78649447461
-
Mesangial pathology in glomerular disease. Targets for therapeutic intervention
-
Scindia, Y. M., Deshmukh, U. S., and Bagavant, H. (2010) Mesangial pathology in glomerular disease. Targets for therapeutic intervention. Adv. Drug Deliv. Rev. 62, 1337-1343
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 1337-1343
-
-
Scindia, Y.M.1
Deshmukh, U.S.2
Bagavant, H.3
-
30
-
-
33744789380
-
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells
-
DOI 10.1152/ajprenal.00268.2005
-
Sours, S., Du, J., Chu, S., Ding, M., Zhou, X. J., and Ma, R. (2006) Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. Am. J. Physiol. Renal Physiol. 290, F1507-F1515 (Pubitemid 43830778)
-
(2006)
American Journal of Physiology - Renal Physiology
, vol.290
, Issue.6
-
-
Sours, S.1
Du, J.2
Chu, S.3
Ding, M.4
Zhou, X.J.5
Ma, R.6
-
32
-
-
0345149546
-
Oxidative stress induces NF-κB nuclear translocation without degradation of IκBα
-
Suppl. II
-
Canty, T. G., Boyle, E. M., Farr, A., Morgan, E. N., Verrier, E. D., and Pohlman, T. H. (1999) Oxidative stress induces NF-κB nuclear translocation without degradation of IκBα. Circulation 100, Suppl. II, 361-364
-
(1999)
Circulation
, vol.100
, pp. 361-364
-
-
Canty, T.G.1
Boyle, E.M.2
Farr, A.3
Morgan, E.N.4
Verrier, E.D.5
Pohlman, T.H.6
-
33
-
-
0037621970
-
NF-κB activation by oxidative stress and inflammation suppresses contractility in colonic circular smooth muscle cells
-
DOI 10.1016/S0016-5085(03)00263-4
-
Shi, X. Z., Lindholm, P. F., and Sarna, S. K. (2003) NF-κB activation by oxidative stress and inflammation suppresses contractility in colonic circular smooth muscle cells. Gastroenterology 124, 1369-1380 (Pubitemid 36531811)
-
(2003)
Gastroenterology
, vol.124
, Issue.5
, pp. 1369-1380
-
-
Shi, X.-Z.1
Lindholm, P.F.2
Sarna, S.K.3
-
34
-
-
84858704647
-
Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways
-
Tsai, K. L., Chiu, T. H., Tsai, M. H., Chen, H. Y., and Ou, H. C. (2012) Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways. Cell Biochem. Biophys. 62, 467-479
-
(2012)
Cell Biochem. Biophys.
, vol.62
, pp. 467-479
-
-
Tsai, K.L.1
Chiu, T.H.2
Tsai, M.H.3
Chen, H.Y.4
Ou, H.C.5
-
35
-
-
80054953932
-
The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
-
Chuang, H. C., Lan, J. L., Chen, D. Y., Yang, C. Y., Chen, Y. M., Li, J. P., Huang, C. Y., Liu, P. E., Wang, X., and Tan, T. H. (2011) The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells. Nat. Immunol. 12, 1113-1118
-
(2011)
Nat. Immunol.
, vol.12
, pp. 1113-1118
-
-
Chuang, H.C.1
Lan, J.L.2
Chen, D.Y.3
Yang, C.Y.4
Chen, Y.M.5
Li, J.P.6
Huang, C.Y.7
Liu, P.E.8
Wang, X.9
Tan, T.H.10
-
36
-
-
33646581238
-
Classical and alternative NF-κB activation pathways and their roles in lymphoid malignancies
-
Nishikori, M. (2005) Classical and alternative NF-κB activation pathways and their roles in lymphoid malignancies. J. Clin. Exp. Hematopathol. 45, 15-24
-
(2005)
J. Clin. Exp. Hematopathol.
, vol.45
, pp. 15-24
-
-
Nishikori, M.1
-
37
-
-
57749084622
-
Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation
-
Müller, M., Essin, K., Hill, K., Beschmann, H., Rubant, S., Schempp, C. M., Gollasch, M., Boehncke, W. H., Harteneck, C., Müller, W. E., and Leuner, K. (2008) Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation. J. Biol. Chem. 283, 33942-33954
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 33942-33954
-
-
Müller, M.1
Essin, K.2
Hill, K.3
Beschmann, H.4
Rubant, S.5
Schempp, C.M.6
Gollasch, M.7
Boehncke, W.H.8
Harteneck, C.9
Müller, W.E.10
Leuner, K.11
-
38
-
-
36849071263
-
Hyperforin - A key constituent of St. John's wort specifically activates TRPC6 channels
-
DOI 10.1096/fj.07-8110com
-
Leuner, K., Kazanski, V., Müller, M., Essin, K., Henke, B., Gollasch, M., Harteneck, C., and Müller, W. E. (2007) Hyperforin. A key constituent of St. John's wort specifically activates TRPC6 channels. FASEB J. 21, 4101-4111 (Pubitemid 350232367)
-
(2007)
FASEB Journal
, vol.21
, Issue.14
, pp. 4101-4111
-
-
Leuner, K.1
Kazanski, V.2
Muller, M.3
Essin, K.4
Henke, B.5
Gollasch, M.6
Harteneck, C.7
Muller, W.E.8
-
39
-
-
0029999693
-
Inhibition of IκB-α phosphorylation and degradation and subsequent NF-κB activation by glutathione peroxidase overexpression
-
Kretz-Remy, C., Mehlen, P., Mirault, M. E., and Arrigo, A. P. (1996) Inhibition of IκB-α phosphorylation and degradation and subsequent NF-κB activation by glutathione peroxidase overexpression. J. Cell Biol. 133, 1083-1093
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1083-1093
-
-
Kretz-Remy, C.1
Mehlen, P.2
Mirault, M.E.3
Arrigo, A.P.4
-
40
-
-
0027207242
-
Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: A mechanism for NF-κB activation
-
Beg, A. A., Finco, T. S., Nantermet, P. V., and Baldwin, A. (1993) Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα. A mechanism for NF-κB activation. Mol. Cell. Biol. 13, 3301-3310 (Pubitemid 23157268)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.6
, pp. 3301-3310
-
-
Beg, A.A.1
Finco, T.S.2
Nantermet, P.V.3
Baldwin Jr., A.S.4
-
41
-
-
0025266685
-
Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB
-
Ghosh, S., and Baltimore, D. (1990) Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB. Nature 344, 678-682
-
(1990)
Nature
, vol.344
, pp. 678-682
-
-
Ghosh, S.1
Baltimore, D.2
-
42
-
-
0042971850
-
Expression of MIS in the testis is downregulated by tumor necrosis factor alpha through the negative regulation of SF-1 transactivation by NF-κB
-
DOI 10.1128/MCB.23.17.6000-6012.2003
-
Hong, C. Y., Park, J. H., Seo, K. H., Kim, J. M., Im, S. Y., Lee, J. W., Choi, H. S., and Lee, K. (2003) Expression of MIS in the testis is down-regulated by tumor necrosis factor α through the negative regulation of SF-1 transactivation by NF-κB. Mol. Cell. Biol. 23, 6000-6012 (Pubitemid 37013081)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.17
, pp. 6000-6012
-
-
Hong, C.Y.1
Park, J.H.2
Seo, K.H.3
Kim, J.-M.4
Im, S.Y.5
Lee, J.W.6
Choi, H.-S.7
Lee, K.8
-
43
-
-
79960144041
-
The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB
-
Moreno, J. A., Izquierdo, M. C., Sanchez-Niño, M. D., Suárez-Alvarez, B., Lopez-Larrea, C., Jakubowski, A., Blanco, J., Ramirez, R., Selgas, R., Ruiz-Ortega, M., Egido, J., Ortiz, A., and Sanz, A. B. (2011) The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB. J. Am. Soc. Nephrol. 22, 1315-1325
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 1315-1325
-
-
Moreno, J.A.1
Izquierdo, M.C.2
Sanchez-Niño, M.D.3
Suárez-Alvarez, B.4
Lopez-Larrea, C.5
Jakubowski, A.6
Blanco, J.7
Ramirez, R.8
Selgas, R.9
Ruiz-Ortega, M.10
Egido, J.11
Ortiz, A.12
Sanz, A.B.13
-
44
-
-
0036067845
-
Histone deacetylases augment cytokine induction of the iNOS gene
-
DOI 10.1097/01.ASN.0000024253.59665.F1
-
Yu, Z., Zhang, W., and Kone, B. C. (2002) Histone Deacetylases augment cytokine induction of the iNOS gene. J. Am. Soc. Nephrol. 13, 2009-2017 (Pubitemid 34790776)
-
(2002)
Journal of the American Society of Nephrology
, vol.13
, Issue.8
, pp. 2009-2017
-
-
Yu, Z.1
Zhang, W.2
Kone, B.C.3
-
45
-
-
69449107940
-
Histone deacetylase-2 is a key regulator of diabetes and transforming growth factor-β1-induced renal injury
-
Noh, H., Oh, E. Y., Seo, J. Y., Yu, M. R., Kim, Y. O., Ha, H., and Lee, H. B. (2009) Histone deacetylase-2 is a key regulator of diabetes and transforming growth factor-β1-induced renal injury. Am. J. Physiol. Renal Physiol. 297, F729-F739
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.297
-
-
Noh, H.1
Oh, E.Y.2
Seo, J.Y.3
Yu, M.R.4
Kim, Y.O.5
Ha, H.6
Lee, H.B.7
-
46
-
-
22844436647
-
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
-
DOI 10.1038/ng1592
-
Reiser, J., Polu, K. R., Möller, C. C., Kenlan, P., Altintas, M. M., Wei, C., Faul, C., Herbert, S., Villegas, I., Avila-Casado, C., McGee, M., Sugimoto, H., Brown, D., Kalluri, R., Mundel, P., Smith, P. L., Clapham, D. E., and Pollak, M. R. (2005) TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat. Genet. 37, 739-744 (Pubitemid 41754891)
-
(2005)
Nature Genetics
, vol.37
, Issue.7
, pp. 739-744
-
-
Reiser, J.1
Polu, K.R.2
Moller, C.C.3
Kenlan, P.4
Altintas, M.M.5
Wei, C.6
Faul, C.7
Herbert, S.8
Villegas, I.9
Avila-Casado, C.10
McGee, M.11
Sugimoto, H.12
Brown, D.13
Kalluri, R.14
Mundel, P.15
Smith, P.L.16
Clapham, D.E.17
Pollak, M.R.18
-
47
-
-
67650257887
-
2/ω-hydroxylase/20-HETE pathways
-
2/ω-hydroxylase/20-HETE pathways. Circ. Res. 104, 1399-1409
-
(2009)
Circ. Res.
, vol.104
, pp. 1399-1409
-
-
Inoue, R.1
Jensen, L.J.2
Jian, Z.3
Shi, J.4
Hai, L.5
Lurie, A.I.6
Henriksen, F.H.7
Salomonsson, M.8
Morita, H.9
Kawarabayashi, Y.10
Mori, M.11
Mori, Y.12
Ito, Y.13
-
48
-
-
84863449854
-
Role of IRAK1 on TNF-induced proliferation and NF-κB activation in human bone marrow mesenchymal stem cells
-
Kim, J. M., Cho, H. H., Lee, S. Y., Hong, C. P., Yang, J. w., Kim, Y. S., Suh, K. T., and Jung, J. S. (2012) Role of IRAK1 on TNF-induced proliferation and NF-κB activation in human bone marrow mesenchymal stem cells. Cell Physiol. Biochem. 30, 49-60
-
(2012)
Cell Physiol. Biochem.
, vol.30
, pp. 49-60
-
-
Kim, J.M.1
Cho, H.H.2
Lee, S.Y.3
Hong, C.P.4
Yang, J.W.5
Kim, Y.S.6
Suh, K.T.7
Jung, J.S.8
-
49
-
-
84862155618
-
The role of Rac1 in the regulation of NF-κB activity, cell proliferation, and cell migration in non-small cell lung carcinoma
-
Gastonguay, A., Berg, T., Hauser, A. D., Schuld, N., Lorimer, E., and Williams, C. L. (2012) The role of Rac1 in the regulation of NF-κB activity, cell proliferation, and cell migration in non-small cell lung carcinoma. Cancer Biol. Ther. 13, 647-656
-
(2012)
Cancer Biol. Ther.
, vol.13
, pp. 647-656
-
-
Gastonguay, A.1
Berg, T.2
Hauser, A.D.3
Schuld, N.4
Lorimer, E.5
Williams, C.L.6
-
50
-
-
66349110029
-
Evidence for inflammatory signaling in idiopathic pulmonary artery hypertension. TRPC6 and nuclear factor-κB
-
Hamid, R., and Newman, J. H. (2009) Evidence for inflammatory signaling in idiopathic pulmonary artery hypertension. TRPC6 and nuclear factor-κB. Circulation 119, 2297-2298
-
(2009)
Circulation
, vol.119
, pp. 2297-2298
-
-
Hamid, R.1
Newman, J.H.2
-
51
-
-
50249160065
-
Loss of classical transient receptor potential 6 channel reduces allergic airway response
-
Sel, S., Rost, B. R., Yildirim, A. O., Sel, B., Kalwa, H., Fehrenbach, H., Renz, H., Gudermann, T., and Dietrich, A. (2008) Loss of classical transient receptor potential 6 channel reduces allergic airway response. Clin. Exp. Allergy 38, 1548-1558
-
(2008)
Clin. Exp. Allergy
, vol.38
, pp. 1548-1558
-
-
Sel, S.1
Rost, B.R.2
Yildirim, A.O.3
Sel, B.4
Kalwa, H.5
Fehrenbach, H.6
Renz, H.7
Gudermann, T.8
Dietrich, A.9
-
52
-
-
0037303378
-
PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression
-
Yu, Y., Sweeney, M., Zhang, S., Platoshyn, O., Landsberg, J., Rothman, A., and Yuan, J. X. (2003) PDGF stimulates pulmonary vascular smooth muscle cell proliferation by up-regulating TRPC6 expression. Am. J. Physiol. Cell Physiol. 284, C316-C330 (Pubitemid 36120070)
-
(2003)
American Journal of Physiology - Cell Physiology
, vol.284
, Issue.2
-
-
Yu, Y.1
Sweeney, M.2
Zhang, S.3
Platoshyn, O.4
Landsberg, J.5
Rothman, A.6
Yuan, J.X.-J.7
-
53
-
-
67650409775
-
Role of TRPC6 channels in VEGF-mediated angiogenesis
-
Ge, R., Tai, Y., Sun, Y., Zhou, K., Yang, S., Cheng, T., Zou, Q., Shen, F., and Wang, Y. (2009) role of TRPC6 channels in VEGF-mediated angiogenesis. Cancer Lett. 283, 43-51
-
(2009)
Cancer Lett.
, vol.283
, pp. 43-51
-
-
Ge, R.1
Tai, Y.2
Sun, Y.3
Zhou, K.4
Yang, S.5
Cheng, T.6
Zou, Q.7
Shen, F.8
Wang, Y.9
-
54
-
-
33845317604
-
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
-
DOI 10.1172/JCI27702
-
Kuwahara, K., Wang, Y., McAnally, J., Richardson, J. A., Bassel-Duby, R., Hill, J. A., and Olson, E. N. (2006) TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J. Clin. Invest. 116, 3114-3126 (Pubitemid 44878626)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.12
, pp. 3114-3126
-
-
Kuwahara, K.1
Wang, Y.2
McAnally, J.3
Richardson, J.A.4
Bassel-Duby, R.5
Hill, J.A.6
Olson, E.N.7
-
55
-
-
1842526076
-
Active repression of antiapoptotic gene expression by RelA(p65) NF-κB
-
DOI 10.1016/S1097-2765(04)00131-5, PII S1097276504001315
-
Campbell, K. J., Rocha, S., and Perkins, N. D. (2004) Active repression of antiapoptotic gene expression by RelA(p65) NF-κB. Mol. Cell 13, 853-865 (Pubitemid 38438480)
-
(2004)
Molecular Cell
, vol.13
, Issue.6
, pp. 853-865
-
-
Campbell, K.J.1
Rocha, S.2
Perkins, N.D.3
-
56
-
-
0035502956
-
Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: A brake to apoptosis in HeLa human carcinoma cells
-
Bottero, V., Busuttil, V., Loubat, A., Magné, N., Fischel, J. L., Milano, G., and Peyron, J. F. (2001) Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin. A brake to apoptosis in HeLa human carcinoma cells. Cancer Res. 61, 7785-7791 (Pubitemid 33049365)
-
(2001)
Cancer Research
, vol.61
, Issue.21
, pp. 7785-7791
-
-
Bottero, V.1
Busuttil, V.2
Loubat, A.3
Magne, N.4
Fischel, J.-L.5
Milano, G.6
Peyron, J.-F.7
-
57
-
-
77957682461
-
Tumor necrosis factor-α suppresses angiotensinogen expression through formation of a p50/p50 homodimer in human renal proximal tubular cells
-
Satou, R., Miyata, K., Katsurada, A., Navar, L. G., and Kobori, H. (2010) Tumor necrosis factor-α suppresses angiotensinogen expression through formation of a p50/p50 homodimer in human renal proximal tubular cells. Am. J. Physiol. Cell Physiol. 299, C750-C759
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.299
-
-
Satou, R.1
Miyata, K.2
Katsurada, A.3
Navar, L.G.4
Kobori, H.5
-
58
-
-
0031935038
-
Functional interference of SP1 and NF-κB through the same DNA binding site
-
Hirano, F., Tanaka, H., Hirano, Y., Hiramoto, M., Handa, H., Makino, I., and Scheidereit, C. (1998) Functional interference of Sp1 and NF-κB through the same DNA binding site. Mol. Cell. Biol. 18, 1266-1274 (Pubitemid 28100890)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.3
, pp. 1266-1274
-
-
Hirano, F.1
Tanaka, H.2
Hirano, Y.3
Hiramoto, M.4
Handa, H.5
Makino, I.6
Scheidereit, C.7
-
60
-
-
15444367188
-
Integration of the NfκB p65 subunit into the vitamin D receptor transcriptional complex: Identification of p65 domains that inhibit 1,25-dihydroxyvitamin D3-stimulated transcription
-
DOI 10.1002/jcb.20143
-
Lu, X., Farmer, P., Rubin, J., and Nanes, M. S. (2004) Integration of the NFκB p65 subunit into the vitamine D receptor transcriptional complex. Identification of p65 domains that inhibit 1,25-dihydroxyvitamine D3-stimulated transcription. J. Cell Biochem. 92, 833-848 (Pubitemid 44264272)
-
(2004)
Journal of Cellular Biochemistry
, vol.92
, Issue.4
, pp. 833-848
-
-
Lu, X.1
Farmer, P.2
Rubin, J.3
Nanes, M.S.4
-
61
-
-
42149102003
-
HDAC activity is required for p65/RelA-dependent repression of PPARδ-mediated transactivation in human keratinocytes
-
DOI 10.1038/sj.jid.5701146, PII 5701146
-
Aarenstrup, L., Flindt, E. N., Otkjaer, K., Kirkegaard, M., Andersen, J. S., and Kristiansen, K. (2008) HDAC activity is required for p65/Rel-dependent repression of PPARγ-mediated transactivation in human keratinocytes. J. Invest. Dermatol. 128, 1095-1106 (Pubitemid 351543195)
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.5
, pp. 1095-1106
-
-
Aarenstrup, L.1
Flindt, E.N.2
Otkjaer, K.3
Kirkegaard, M.4
Andersen, J.S.5
Kristiansen, K.6
-
62
-
-
75149128159
-
Effects of histone deacetylase inhibitors on rat mesangial cells
-
Freidkin, I., Herman, M., Tobar, A., Chagnac, A., Ori, Y., Korzets, A., and Gafter, U. (2010) Effects of histone deacetylase inhibitors on rat mesangial cells. Am. J. Physiol. Renal Physiol. 298, F426-F434
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.298
-
-
Freidkin, I.1
Herman, M.2
Tobar, A.3
Chagnac, A.4
Ori, Y.5
Korzets, A.6
Gafter, U.7
-
63
-
-
33846976509
-
SIRT1 inhibits transforming growth factor β-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation
-
DOI 10.1074/jbc.M605904200
-
Kume, S., Haneda, M., Kanasaki, K., Sugimoto, T., Araki, S., Isshiki, K., Isono, M., Uzu, T., Guarente, L., Kashiwagi, A., and Koya, D. (2007) SIRT1 inhibits transforming growth factor β-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation. J. Biol. Chem. 282, 151-158 (Pubitemid 47076643)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.1
, pp. 151-158
-
-
Kume, S.1
Haneda, M.2
Kanasaki, K.3
Sugimoto, T.4
Araki, S.-I.5
Isshiki, K.6
Isono, M.7
Uzu, T.8
Guarente, L.9
Kashiwagi, A.10
Koya, D.11
-
64
-
-
33644862022
-
Targeted histone H4 acetylation via phosphoinositide 3-kinase- and p70s6-kinase-dependent pathways inhibits iNOS induction in mesangial cells
-
DOI 10.1152/ajprenal.00316.2005
-
Yu, Z., and Kone, B. C. (2006) Targeted histone H4 acetylation via phosphoinositide 3-kinase- and p70s6-kinase-dependent pathways inhibits iNOS induction in mesangial cells. Am. J. Physiol. Renal Physiol. 290, F496-F502 (Pubitemid 43725003)
-
(2006)
American Journal of Physiology - Renal Physiology
, vol.290
, Issue.2
-
-
Yu, Z.1
Kone, B.C.2
-
65
-
-
34047272823
-
TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells
-
DOI 10.1016/j.gene.2007.01.016, PII S0378111907000376
-
Zhu, N. L., Li, C., Huang, H. H., Sebald, M., Londhe, V. A., Heisterkamp, N., Warburton, D., Bellusci, S., and Minoo, P. (2007) TNF-α represses transcription of human bone morphogenetic protein-4 in lung epithelial cells. Gene 393, 70-80 (Pubitemid 46551526)
-
(2007)
Gene
, vol.393
, Issue.1-2
, pp. 70-80
-
-
Zhu, N.-L.1
Li, C.2
Huang, H.H.3
Sebald, M.4
Londhe, V.A.5
Heisterkamp, N.6
Warburton, D.7
Bellusci, S.8
Minoo, P.9
|