3-Thiomethyl-5,6-(dimethoxyphenyl)-1,2,4-triazine improves neurite outgrowth and modulates MAPK phosphorylation and HSPs expression in H2O2-exposed PC12 cells

Toxicology in Vitro

Volumn 26, Issue 6, 2012, Pages 907-914

  Khodagholi, Fariba ^a   Tusi, Solaleh Khoramian ^a   Alamdary, Shabnam Zeighamy ^a   Amini, Mohsen ^b   Ansari, Niloufar ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

HSPs; MAPKs; Neurite outgrowth; PC12 cells; Triazine derivatives

Indexed keywords

3 THIOMETHYL 5,6 (DIMETHOXYPHENYL) 1,2,4 TRIAZINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; NERVE FIBER GROWTH; NERVE GROWTH; NEURITOGENESIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL SURVIVAL; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTOR; NEURITES; NEUROPROTECTIVE AGENTS; PC12 CELLS; PHOSPHORYLATION; RATS; TRIAZINES;

EID: 84863832586     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.04.015     Document Type: Article

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