메뉴 건너뛰기




Volumn 17, Issue 23, 2011, Pages 2801-2811

Adiponectin, a key adipokine in obesity related liver diseases

Author keywords

Adiponectin; Adipose tissue; Hepatic steatosis; Non alcoholic steatohepa titis; Obesity

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; ALANINE AMINOTRANSFERASE; ALDEHYDE OXIDASE; ALPHA TOCOPHEROL; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; CLOFIBRATE; CYTOCHROME P450 2E1; FENOFIBRATE; GAMMA GLUTAMYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; PENTOXIFYLLINE; PIOGLITAZONE; REACTIVE OXYGEN METABOLITE; SQUALENE SYNTHASE; STAT3 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSFERRIN; TRANSFORMING GROWTH FACTOR BETA; VERY LOW DENSITY LIPOPROTEIN;

EID: 79959672175     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v17.i23.2801     Document Type: Review
Times cited : (231)

References (154)
  • 1
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004; 114: 147-152
    • (2004) J Clin Invest , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 2
    • 4544241860 scopus 로고    scopus 로고
    • Adiponectin, the missing link in insulin resistance and obesity
    • Gil-Campos M, Cañete RR, Gil A. Adiponectin, the missing link in insulin resistance and obesity. Clin Nutr 2004; 23: 963-974
    • (2004) Clin Nutr , vol.23 , pp. 963-974
    • Gil-Campos, M.1    Cañete, R.R.2    Gil, A.3
  • 3
    • 42949088997 scopus 로고    scopus 로고
    • The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance
    • Goossens GH. The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance. Physiol Behav 2008; 94: 206-218
    • (2008) Physiol Behav , vol.94 , pp. 206-218
    • Goossens, G.H.1
  • 4
    • 34548819916 scopus 로고    scopus 로고
    • Present and future therapeutic strategies in non-alcoholic fatty liver disease
    • Calamita G, Portincasa P. Present and future therapeutic strategies in non-alcoholic fatty liver disease. Expert Opin Ther Targets 2007; 11: 1231-1249
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 1231-1249
    • Calamita, G.1    Portincasa, P.2
  • 5
    • 55849106577 scopus 로고    scopus 로고
    • Role of body fat distribution and the metabolic complications of obesity
    • Jensen MD. Role of body fat distribution and the metabolic complications of obesity. J Clin Endocrinol Metab 2008; 93: S57-S63
    • (2008) J Clin Endocrinol Metab , vol.93
    • Jensen, M.D.1
  • 6
    • 21244450310 scopus 로고    scopus 로고
    • Mechanisms of disease: Adipocytokines and visceral adipose tissue--emerging role in nonalcoholic fatty liver disease
    • Schäffer A, Schölmerich J, Büchler C. Mechanisms of disease: adipocytokines and visceral adipose tissue--emerging role in nonalcoholic fatty liver disease. Nat Clin Pract Gastro-enterol Hepatol 2005; 2: 273-280
    • (2005) Nat Clin Pract Gastro-enterol Hepatol , vol.2 , pp. 273-280
    • Schäffer, A.1    Schölmerich, J.2    Büchler, C.3
  • 9
    • 0035052940 scopus 로고    scopus 로고
    • What are the physical characteristics associated with a normal metabolic profle despite a high level of obesity in postmenopausal women?
    • Brochu M, Tchernof A, Dionne IJ, Sites CK, Eltabbakh GH, Sims EA, Poehlman ET. What are the physical characteristics associated with a normal metabolic profle despite a high level of obesity in postmenopausal women? J Clin En-docrinol Metab 2001; 86: 1020-1025
    • (2001) J Clin En-docrinol Metab , vol.86 , pp. 1020-1025
    • Brochu, M.1    Tchernof, A.2    Dionne, I.J.3    Sites, C.K.4    Eltabbakh, G.H.5    Sims, E.A.6    Poehlman, E.T.7
  • 13
    • 34548477639 scopus 로고    scopus 로고
    • Adipose tissue macrophages
    • Zeyda M, Stulnig TM. Adipose tissue macrophages. Immunol Lett 2007; 112: 61-67
    • (2007) Immunol Lett , vol.112 , pp. 61-67
    • Zeyda, M.1    Stulnig, T.M.2
  • 15
    • 4243150843 scopus 로고    scopus 로고
    • The role of TNF-alpha in insulin resistance
    • Borst SE. The role of TNF-alpha in insulin resistance. Endocrine 2004; 23: 177-182
    • (2004) Endocrine , vol.23 , pp. 177-182
    • Borst, S.E.1
  • 16
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic infammation in obese humans
    • Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic infammation in obese humans. Diabetes 2007; 56: 1010-1013
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3    Scherer, P.E.4    Klein, S.5
  • 19
    • 0025190892 scopus 로고
    • Interleukin-6 and the acute phase response
    • Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 1990; 265: 621-636
    • (1990) Biochem J , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 20
    • 33747034520 scopus 로고    scopus 로고
    • Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c
    • Biddinger SB, Miyazaki M, Boucher J, Ntambi JM, Kahn CR. Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c. Diabetes 2006; 55: 2032-2041
    • (2006) Diabetes , vol.55 , pp. 2032-2041
    • Biddinger, S.B.1    Miyazaki, M.2    Boucher, J.3    Ntambi, J.M.4    Kahn, C.R.5
  • 22
    • 68049110522 scopus 로고    scopus 로고
    • The metabolic syndrome: How it may influence hepatic stellate cell activation and hepatic fbrosis
    • Lanthier N, Horsmans Y, Leclercq IA. The metabolic syndrome: how it may influence hepatic stellate cell activation and hepatic fbrosis. Curr Opin Clin Nutr Metab Care 2009; 12: 404-411
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , pp. 404-411
    • Lanthier, N.1    Horsmans, Y.2    Leclercq, I.A.3
  • 24
    • 38949125405 scopus 로고    scopus 로고
    • Post-translational modifications of adiponectin: Mechanisms and functional implications
    • Wang Y, Lam KS, Yau MH, Xu A. Post-translational modifications of adiponectin: mechanisms and functional implications. Biochem J 2008; 409: 623-633
    • (2008) Biochem J , vol.409 , pp. 623-633
    • Wang, Y.1    Lam, K.S.2    Yau, M.H.3    Xu, A.4
  • 27
    • 58249117645 scopus 로고    scopus 로고
    • Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin
    • Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Ge G, Spooner E, Hug C, Gimeno R, Lodish HF. Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. FASEB J 2009; 23: 241-258
    • (2009) FASEB J , vol.23 , pp. 241-258
    • Wong, G.W.1    Krawczyk, S.A.2    Kitidis-Mitrokostas, C.3    Ge, G.4    Spooner, E.5    Hug, C.6    Gimeno, R.7    Lodish, H.F.8
  • 28
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 2001; 98: 2005-2010
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2005-2010
    • Fruebis, J.1    Tsao, T.S.2    Javorschi, S.3    Ebbets-Reed, D.4    Erickson, M.R.5    Yen, F.T.6    Bihain, B.E.7    Lodish, H.F.8
  • 32
    • 10844246291 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely associated with nonalcoholic hepatic steatosis in obese individuals
    • Targher G, Bertolini L, Scala L, Poli F, Zenari L, Falezza G. Decreased plasma adiponectin concentrations are closely associated with nonalcoholic hepatic steatosis in obese individuals. Clin Endocrinol (Oxf) 2004; 61: 700-703
    • (2004) Clin Endocrinol (Oxf) , vol.61 , pp. 700-703
    • Targher, G.1    Bertolini, L.2    Scala, L.3    Poli, F.4    Zenari, L.5    Falezza, G.6
  • 34
    • 56649107955 scopus 로고    scopus 로고
    • Hepatic, cardiovascular, and endocrine outcomes of the histological sub-phenotypes of nonalcoholic fatty liver disease
    • Rubinstein E, Lavine JE, Schwimmer JB. Hepatic, cardiovascular, and endocrine outcomes of the histological sub-phenotypes of nonalcoholic fatty liver disease. Semin Liver Dis 2008; 28: 380-385
    • (2008) Semin Liver Dis , vol.28 , pp. 380-385
    • Rubinstein, E.1    Lavine, J.E.2    Schwimmer, J.B.3
  • 37
    • 34249715820 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis in children
    • Roberts EA. Non-alcoholic steatohepatitis in children. Clin Liver Dis 2007; 11: 155-172, x
    • (2007) Clin Liver Dis , vol.11 , Issue.x , pp. 155-172
    • Roberts, E.A.1
  • 38
    • 67649411827 scopus 로고    scopus 로고
    • Protective roles of adipo-nectin in obesity-related fatty liver diseases: Mechanisms and therapeutic implications
    • Wang Y, Zhou M, Lam KS, Xu A. Protective roles of adipo-nectin in obesity-related fatty liver diseases: mechanisms and therapeutic implications. Arq Bras Endocrinol Metabol 2009; 53: 201-212
    • (2009) Arq Bras Endocrinol Metabol , vol.53 , pp. 201-212
    • Wang, Y.1    Zhou, M.2    Lam, K.S.3    Xu, A.4
  • 39
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic ste-atohepatitis: Summary of an AASLD Single Topic Conference
    • Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic ste-atohepatitis: summary of an AASLD Single Topic Conference. Hepatology 2003; 37: 1202-1219
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 40
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003; 98: 960-967
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 41
    • 33747517955 scopus 로고    scopus 로고
    • The epidemiology of nonalcoholic fatty liver disease in adults
    • Clark JM. The epidemiology of nonalcoholic fatty liver disease in adults. J Clin Gastroenterol 2006; 40 Suppl 1: S5-S10
    • (2006) J Clin Gastroenterol , vol.40 , Issue.SUPPL. 1
    • Clark, J.M.1
  • 42
    • 16044363694 scopus 로고    scopus 로고
    • Clinical hepatology: Profile of an urban, hospital-based practice
    • Byron D, Minuk GY. Clinical hepatology: profile of an urban, hospital-based practice. Hepatology 1996; 24: 813-815
    • (1996) Hepatology , vol.24 , pp. 813-815
    • Byron, D.1    Minuk, G.Y.2
  • 43
    • 0021272756 scopus 로고
    • The liver in consecutive patients with morbid obesity: A clinical, morphological, and biochemical study
    • Andersen T, Christoffersen P, Gluud C. The liver in consecutive patients with morbid obesity: a clinical, morphological, and biochemical study. Int J Obes 1984; 8: 107-115
    • (1984) Int J Obes , vol.8 , pp. 107-115
    • Andersen, T.1    Christoffersen, P.2    Gluud, C.3
  • 44
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-1231
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 45
    • 49649091383 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: An overview of prevalence, diagnosis, pathogenesis and treatment considerations
    • Preiss D, Sattar N. Non-alcoholic fatty liver disease: an overview of prevalence, diagnosis, pathogenesis and treatment considerations. Clin Sci (Lond) 2008; 115: 141-150
    • (2008) Clin Sci (Lond) , vol.115 , pp. 141-150
    • Preiss, D.1    Sattar, N.2
  • 46
    • 66349125337 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Erickson SK. Nonalcoholic fatty liver disease. J Lipid Res 2009; 50 Suppl: S412-S416
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Erickson, S.K.1
  • 48
    • 62349142248 scopus 로고    scopus 로고
    • RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: A comparative magnetic resonance imaging study
    • Müssig K, Staiger H, Machicao F, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU. RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study. Metabolism 2009; 58: 519-524
    • (2009) Metabolism , vol.58 , pp. 519-524
    • Müssig, K.1    Staiger, H.2    Machicao, F.3    Thamer, C.4    Machann, J.5    Schick, F.6    Claussen, C.D.7    Stefan, N.8    Fritsche, A.9    Häring, H.U.10
  • 49
    • 33846098849 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study
    • Loos RJ, Ruchat S, Rankinen T, Tremblay A, Pérusse L, Bouchard C. Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study. Am J Clin Nutr 2007; 85: 26-34
    • (2007) Am J Clin Nutr , vol.85 , pp. 26-34
    • Loos, R.J.1    Ruchat, S.2    Rankinen, T.3    Tremblay, A.4    Pérusse, L.5    Bouchard, C.6
  • 50
    • 63049122519 scopus 로고    scopus 로고
    • Correlation between adiponectin polymorphisms and non-alcoholic fatty liver disease with or without metabolic syndrome in Chinese population
    • Wang ZL, Xia B, Shrestha U, Jiang L, Ma CW, Chen Q, Chen H, Hu ZG. Correlation between adiponectin polymorphisms and non-alcoholic fatty liver disease with or without metabolic syndrome in Chinese population. J Endocrinol Invest 2008; 31: 1086-1091
    • (2008) J Endocrinol Invest , vol.31 , pp. 1086-1091
    • Wang, Z.L.1    Xia, B.2    Shrestha, U.3    Jiang, L.4    Ma, C.W.5    Chen, Q.6    Chen, H.7    Hu, Z.G.8
  • 51
    • 12844280471 scopus 로고    scopus 로고
    • Racial and ethnic distribution of nonalcoholic fatty liver in persons with newly diagnosed chronic liver disease
    • Weston SR, Leyden W, Murphy R, Bass NM, Bell BP, Ma-nos MM, Terrault NA. Racial and ethnic distribution of nonalcoholic fatty liver in persons with newly diagnosed chronic liver disease. Hepatology 2005; 41: 372-379
    • (2005) Hepatology , vol.41 , pp. 372-379
    • Weston, S.R.1    Leyden, W.2    Murphy, R.3    Bass, N.M.4    Bell, B.P.5    Ma-Nos, M.M.6    Terrault, N.A.7
  • 52
    • 61749092425 scopus 로고    scopus 로고
    • Influence of ethnicity on histological differences in non-alcoholic fatty liver disease
    • Mohanty SR, Troy TN, Huo D, ÓBrien BL, Jensen DM, Hart J. Influence of ethnicity on histological differences in non-alcoholic fatty liver disease. J Hepatol 2009; 50: 797-804
    • (2009) J Hepatol , vol.50 , pp. 797-804
    • Mohanty, S.R.1    Troy, T.N.2    Huo, D.3    Óbrien, B.L.4    Jensen, D.M.5    Hart, J.6
  • 54
    • 44849125451 scopus 로고    scopus 로고
    • Genes and nonalcoholic fatty liver disease
    • Wilfred de Alwis NM, Day CP. Genes and nonalcoholic fatty liver disease. Curr Diab Rep 2008; 8: 156-163
    • (2008) Curr Diab Rep , vol.8 , pp. 156-163
    • Wilfred de Alwis, N.M.1    Day, C.P.2
  • 55
    • 33847008303 scopus 로고    scopus 로고
    • Genetics of alcoholic liver disease and nonalcoholic fatty liver disease
    • Wilfred de Alwis NM, Day CP. Genetics of alcoholic liver disease and nonalcoholic fatty liver disease. Semin Liver Dis 2007; 27: 44-54
    • (2007) Semin Liver Dis , vol.27 , pp. 44-54
    • Wilfred de Alwis, N.M.1    Day, C.P.2
  • 57
    • 77956636268 scopus 로고    scopus 로고
    • The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
    • Rotman Y, Koh C, Zmuda JM, Kleiner DE, Liang TJ. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology 2010; 52: 894-903
    • (2010) Hepatology , vol.52 , pp. 894-903
    • Rotman, Y.1    Koh, C.2    Zmuda, J.M.3    Kleiner, D.E.4    Liang, T.J.5
  • 63
    • 52049097577 scopus 로고    scopus 로고
    • The link between abdominal obesity and the metabolic syndrome
    • Phillips LK, Prins JB. The link between abdominal obesity and the metabolic syndrome. Curr Hypertens Rep 2008; 10: 156-164
    • (2008) Curr Hypertens Rep , vol.10 , pp. 156-164
    • Phillips, L.K.1    Prins, J.B.2
  • 64
    • 42449119389 scopus 로고    scopus 로고
    • Adi-ponectin and adiponectin receptors in obesity-linked insulin resistance
    • discussion 176-182, 200-203
    • Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K. Adi-ponectin and adiponectin receptors in obesity-linked insulin resistance. Novartis Found Symp 2007; 286: 164-176; discussion 176-182, 200-203
    • (2007) Novartis Found Symp , vol.286 , pp. 164-176
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3    Hara, K.4    Ueki, K.5
  • 66
    • 58149506718 scopus 로고    scopus 로고
    • The role of fat topology in the risk of disease
    • Matsuzawa Y. The role of fat topology in the risk of disease. Int J Obes (Lond) 2008; 32 Suppl 7: S83-S92
    • (2008) Int J Obes (Lond) , vol.32 , Issue.SUPPL. 7
    • Matsuzawa, Y.1
  • 70
    • 34547539428 scopus 로고    scopus 로고
    • Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis
    • Shimada M, Kawahara H, Ozaki K, Fukura M, Yano H, Tsuchishima M, Tsutsumi M, Takase S. Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis. Am J Gastroenterol 2007; 102: 1931-1938
    • (2007) Am J Gastroenterol , vol.102 , pp. 1931-1938
    • Shimada, M.1    Kawahara, H.2    Ozaki, K.3    Fukura, M.4    Yano, H.5    Tsuchishima, M.6    Tsutsumi, M.7    Takase, S.8
  • 71
    • 24044538551 scopus 로고    scopus 로고
    • Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner
    • Wang Y, Lam KS, Xu JY, Lu G, Xu LY, Cooper GJ, Xu A. Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem 2005; 280: 18341-18347
    • (2005) J Biol Chem , vol.280 , pp. 18341-18347
    • Wang, Y.1    Lam, K.S.2    Xu, J.Y.3    Lu, G.4    Xu, L.Y.5    Cooper, G.J.6    Xu, A.7
  • 73
    • 25144525699 scopus 로고    scopus 로고
    • Adiponectin inhibits the binding of low-density lipopro-tein to biglycan, a vascular proteoglycan
    • Kobayashi K, Inoguchi T, Sonoda N, Sekiguchi N, Nawata H. Adiponectin inhibits the binding of low-density lipopro-tein to biglycan, a vascular proteoglycan. Biochem Biophys Res Commun 2005; 335: 66-70
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 66-70
    • Kobayashi, K.1    Inoguchi, T.2    Sonoda, N.3    Sekiguchi, N.4    Nawata, H.5
  • 74
  • 77
    • 14144249423 scopus 로고    scopus 로고
    • Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study
    • Vuppalanchi R, Marri S, Kolwankar D, Considine RV, Chalasani N. Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study. J Clin Gastroenterol 2005; 39: 237-242
    • (2005) J Clin Gastroenterol , vol.39 , pp. 237-242
    • Vuppalanchi, R.1    Marri, S.2    Kolwankar, D.3    Considine, R.V.4    Chalasani, N.5
  • 85
    • 58849119649 scopus 로고    scopus 로고
    • Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease
    • Ma H, Gomez V, Lu L, Yang X, Wu X, Xiao SY. Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2009; 24: 233-237
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 233-237
    • Ma, H.1    Gomez, V.2    Lu, L.3    Yang, X.4    Wu, X.5    Xiao, S.Y.6
  • 89
    • 70350399324 scopus 로고    scopus 로고
    • Fenofbrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis
    • Rahman SM, Qadri I, Janssen RC, Friedman JE. Fenofbrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis. J Lipid Res 2009; 50: 2193-2202
    • (2009) J Lipid Res , vol.50 , pp. 2193-2202
    • Rahman, S.M.1    Qadri, I.2    Janssen, R.C.3    Friedman, J.E.4
  • 90
    • 77951757036 scopus 로고    scopus 로고
    • AdipoR2 is transcriptionally regulated by ER stress-inducible ATF3 in HepG2 human hepatocyte cells
    • Koh IU, Lim JH, Joe MK, Kim WH, Jung MH, Yoon JB, Song J. AdipoR2 is transcriptionally regulated by ER stress-inducible ATF3 in HepG2 human hepatocyte cells. FEBS J 2010; 277: 2304-2317
    • (2010) FEBS J , vol.277 , pp. 2304-2317
    • Koh, I.U.1    Lim, J.H.2    Joe, M.K.3    Kim, W.H.4    Jung, M.H.5    Yoon, J.B.6    Song, J.7
  • 91
    • 3042744039 scopus 로고    scopus 로고
    • Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemody-namics
    • Tietge UJ, Böker KH, Manns MP, Bahr MJ. Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemody-namics. Am J Physiol Endocrinol Metab 2004; 287: E82-E89
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Tietge, U.J.1    Böker, K.H.2    Manns, M.P.3    Bahr, M.J.4
  • 92
    • 34547460043 scopus 로고    scopus 로고
    • Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease
    • Qureshi K, Abrams GA. Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease. World J Gastroenterol 2007; 13: 3540-3553
    • (2007) World J Gastroenterol , vol.13 , pp. 3540-3553
    • Qureshi, K.1    Abrams, G.A.2
  • 93
    • 0036678916 scopus 로고    scopus 로고
    • Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women
    • Matsubara M, Maruoka S, Katayose S. Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women. Eur J Endocrinol 2002; 147: 173-180
    • (2002) Eur J Endocrinol , vol.147 , pp. 173-180
    • Matsubara, M.1    Maruoka, S.2    Katayose, S.3
  • 94
    • 0038541576 scopus 로고    scopus 로고
    • Adiponectin represents an independent cardiovascular risk factor predicting serum HDL-cholesterol levels in type 2 diabetes
    • Zietz B, Herfarth H, Paul G, Ehling A, Müller-Ladner U, Schölmerich J, Schäffer A. Adiponectin represents an independent cardiovascular risk factor predicting serum HDL-cholesterol levels in type 2 diabetes. FEBS Lett 2003; 545: 103-104
    • (2003) FEBS Lett , vol.545 , pp. 103-104
    • Zietz, B.1    Herfarth, H.2    Paul, G.3    Ehling, A.4    Müller-Ladner, U.5    Schölmerich, J.6    Schäffer, A.7
  • 96
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003; 112: 91-100
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 97
    • 48249117609 scopus 로고    scopus 로고
    • Adiponec-tin reduces plasma triglyceride by increasing VLDL triglyc-eride catabolism
    • Qiao L, Zou C, van der Westhuyzen DR, Shao J. Adiponec-tin reduces plasma triglyceride by increasing VLDL triglyc-eride catabolism. Diabetes 2008; 57: 1824-1833
    • (2008) Diabetes , vol.57 , pp. 1824-1833
    • Qiao, L.1    Zou, C.2    van der Westhuyzen, D.R.3    Shao, J.4
  • 98
    • 0036864358 scopus 로고    scopus 로고
    • Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
    • Hardie DG, Pan DA. Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase. Biochem Soc Trans 2002; 30: 1064-1070
    • (2002) Biochem Soc Trans , vol.30 , pp. 1064-1070
    • Hardie, D.G.1    Pan, D.A.2
  • 99
    • 58149499174 scopus 로고    scopus 로고
    • Physiological and pathophysi-ological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases
    • Yamauchi T, Kadowaki T. Physiological and pathophysi-ological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases. Int J Obes (Lond) 2008; 32 Suppl 7: S13-S18
    • (2008) Int J Obes (Lond) , vol.32 , Issue.SUPPL. 7
    • Yamauchi, T.1    Kadowaki, T.2
  • 100
    • 0032816777 scopus 로고    scopus 로고
    • Peroxisome proliferator-ac-tivated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular infammation and atherosclerosis
    • Fruchart JC, Duriez P, Staels B. Peroxisome proliferator-ac-tivated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular infammation and atherosclerosis. Curr Opin Lipidol 1999; 10: 245-257
    • (1999) Curr Opin Lipidol , vol.10 , pp. 245-257
    • Fruchart, J.C.1    Duriez, P.2    Staels, B.3
  • 102
    • 0001513966 scopus 로고    scopus 로고
    • Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
    • Yang SQ, Lin HZ, Lane MD, Clemens M, Diehl AM. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci USA 1997; 94: 2557-2562
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2557-2562
    • Yang, S.Q.1    Lin, H.Z.2    Lane, M.D.3    Clemens, M.4    Diehl, A.M.5
  • 104
    • 67649306197 scopus 로고    scopus 로고
    • Systematic review of risk factors for fbrosis progression in nonalcoholic steatohepatitis
    • Argo CK, Northup PG, Al-Osaimi AM, Caldwell SH. Systematic review of risk factors for fbrosis progression in nonalcoholic steatohepatitis. J Hepatol 2009; 51: 371-379
    • (2009) J Hepatol , vol.51 , pp. 371-379
    • Argo, C.K.1    Northup, P.G.2    Al-Osaimi, A.M.3    Caldwell, S.H.4
  • 106
    • 33947627537 scopus 로고    scopus 로고
    • Adiponectin as an anti-inflammatory factor
    • Ouchi N, Walsh K. Adiponectin as an anti-inflammatory factor. Clin Chim Acta 2007; 380: 24-30
    • (2007) Clin Chim Acta , vol.380 , pp. 24-30
    • Ouchi, N.1    Walsh, K.2
  • 107
    • 46249092855 scopus 로고    scopus 로고
    • Adipo-nectin decreases C-reactive protein synthesis and secretion from endothelial cells: Evidence for an adipose tissue-vascular loop
    • Devaraj S, Torok N, Dasu MR, Samols D, Jialal I. Adipo-nectin decreases C-reactive protein synthesis and secretion from endothelial cells: evidence for an adipose tissue-vascular loop. Arterioscler Thromb Vasc Biol 2008; 28: 1368-1374
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1368-1374
    • Devaraj, S.1    Torok, N.2    Dasu, M.R.3    Samols, D.4    Jialal, I.5
  • 108
    • 0037119375 scopus 로고    scopus 로고
    • Oligo-merization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30)
    • Tsao TS, Murrey HE, Hug C, Lee DH, Lodish HF. Oligo-merization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem 2002; 277: 29359-29362
    • (2002) J Biol Chem , vol.277 , pp. 29359-29362
    • Tsao, T.S.1    Murrey, H.E.2    Hug, C.3    Lee, D.H.4    Lodish, H.F.5
  • 109
    • 34547556455 scopus 로고    scopus 로고
    • Short-term treatment of RAW264.7 macrophages with adi-ponectin increases tumor necrosis factor-alpha (TNF-alpha) expression via ERK1/2 activation and Egr-1 expression: Role of TNF-alpha in adiponectin-stimulated interleukin-10 production
    • Park PH, McMullen MR, Huang H, Thakur V, Nagy LE. Short-term treatment of RAW264.7 macrophages with adi-ponectin increases tumor necrosis factor-alpha (TNF-alpha) expression via ERK1/2 activation and Egr-1 expression: role of TNF-alpha in adiponectin-stimulated interleukin-10 production. J Biol Chem 2007; 282: 21695-21703
    • (2007) J Biol Chem , vol.282 , pp. 21695-21703
    • Park, P.H.1    McMullen, M.R.2    Huang, H.3    Thakur, V.4    Nagy, L.E.5
  • 110
    • 23044454354 scopus 로고    scopus 로고
    • Inhibition by adiponectin of IL-8 production by human macro-phages upon coculturing with late apoptotic cells
    • Saijo S, Nagata K, Nakano Y, Tobe T, Kobayashi Y. Inhibition by adiponectin of IL-8 production by human macro-phages upon coculturing with late apoptotic cells. Biochem Biophys Res Commun 2005; 334: 1180-1183
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 1180-1183
    • Saijo, S.1    Nagata, K.2    Nakano, Y.3    Tobe, T.4    Kobayashi, Y.5
  • 113
    • 33748976391 scopus 로고    scopus 로고
    • Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and inter-leukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes
    • Abke S, Neumeier M, Weigert J, Wehrwein G, Eggenhofer E, Schäffer A, Maier K, Aslanidis C, Schölmerich J, Buechler C. Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and inter-leukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes. Cardiovasc Diabetol 2006; 5: 17
    • (2006) Cardiovasc Diabetol , vol.5 , pp. 17
    • Abke, S.1    Neumeier, M.2    Weigert, J.3    Wehrwein, G.4    Eggenhofer, E.5    Schäffer, A.6    Maier, K.7    Aslanidis, C.8    Schölmerich, J.9    Buechler, C.10
  • 115
    • 33745142600 scopus 로고    scopus 로고
    • Chemokine induction by the adipocyte-derived cytokine adiponectin
    • Rovin BH, Song H. Chemokine induction by the adipocyte-derived cytokine adiponectin. Clin Immunol 2006; 120: 99-105
    • (2006) Clin Immunol , vol.120 , pp. 99-105
    • Rovin, B.H.1    Song, H.2
  • 116
    • 39149088929 scopus 로고    scopus 로고
    • Adiponectin and infammation: Consensus and controversy
    • Fantuzzi G. Adiponectin and infammation: consensus and controversy. J Allergy Clin Immunol 2008; 121: 326-330
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 326-330
    • Fantuzzi, G.1
  • 120
    • 30344438527 scopus 로고    scopus 로고
    • Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin tox-icity
    • Hanson JC, Bostick MK, Campe CB, Kodali P, Lee G, Yan J, Maher JJ. Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin tox-icity. J Hepatol 2006; 44: 359-367
    • (2006) J Hepatol , vol.44 , pp. 359-367
    • Hanson, J.C.1    Bostick, M.K.2    Campe, C.B.3    Kodali, P.4    Lee, G.5    Yan, J.6    Maher, J.J.7
  • 121
    • 63049111215 scopus 로고    scopus 로고
    • Full-length adiponectin protects hepatocytes from palmitate-induced apoptosis via inhibition of c-Jun NH2 terminal kinase
    • Jung TW, Lee YJ, Lee MW, Kim SM, Jung TW. Full-length adiponectin protects hepatocytes from palmitate-induced apoptosis via inhibition of c-Jun NH2 terminal kinase. FEBS J 2009; 276: 2278-2284
    • (2009) FEBS J , vol.276 , pp. 2278-2284
    • Jung, T.W.1    Lee, Y.J.2    Lee, M.W.3    Kim, S.M.4    Jung, T.W.5
  • 123
    • 33750562169 scopus 로고    scopus 로고
    • Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome
    • Fujita K, Nishizawa H, Funahashi T, Shimomura I, Shima-bukuro M. Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome. Circ J 2006; 70: 1437-1442
    • (2006) Circ J , vol.70 , pp. 1437-1442
    • Fujita, K.1    Nishizawa, H.2    Funahashi, T.3    Shimomura, I.4    Shima-Bukuro, M.5
  • 125
    • 0034092716 scopus 로고    scopus 로고
    • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
    • Leclercq IA, Farrell GC, Field J, Bell DR, Gonzalez FJ, Robertson GR. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest 2000; 105: 1067-1075
    • (2000) J Clin Invest , vol.105 , pp. 1067-1075
    • Leclercq, I.A.1    Farrell, G.C.2    Field, J.3    Bell, D.R.4    Gonzalez, F.J.5    Robertson, G.R.6
  • 126
    • 0029829455 scopus 로고    scopus 로고
    • Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
    • Weltman MD, Farrell GC, Liddle C. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology 1996; 111: 1645-1653
    • (1996) Gastroenterology , vol.111 , pp. 1645-1653
    • Weltman, M.D.1    Farrell, G.C.2    Liddle, C.3
  • 127
    • 42449117257 scopus 로고    scopus 로고
    • Mammalian aldehyde oxi-dases: Genetics, evolution and biochemistry
    • Garattini E, Fratelli M, Terao M. Mammalian aldehyde oxi-dases: genetics, evolution and biochemistry. Cell Mol Life Sci 2008; 65: 1019-1048
    • (2008) Cell Mol Life Sci , vol.65 , pp. 1019-1048
    • Garattini, E.1    Fratelli, M.2    Terao, M.3
  • 128
    • 33947723940 scopus 로고    scopus 로고
    • Characterization of superoxide production from aldehyde oxidase: An important source of oxidants in biological tissues
    • Kundu TK, Hille R, Velayutham M, Zweier JL. Characterization of superoxide production from aldehyde oxidase: an important source of oxidants in biological tissues. Arch Biochem Biophys 2007; 460: 113-121
    • (2007) Arch Biochem Biophys , vol.460 , pp. 113-121
    • Kundu, T.K.1    Hille, R.2    Velayutham, M.3    Zweier, J.L.4
  • 130
    • 33744538682 scopus 로고    scopus 로고
    • Modern pathogenetic concepts of liver fbrosis suggest stellate cells and TGF-beta as major players and therapeutic targets
    • Gressner AM, Weiskirchen R. Modern pathogenetic concepts of liver fbrosis suggest stellate cells and TGF-beta as major players and therapeutic targets. J Cell Mol Med 2006; 10: 76-99
    • (2006) J Cell Mol Med , vol.10 , pp. 76-99
    • Gressner, A.M.1    Weiskirchen, R.2
  • 132
    • 19544378172 scopus 로고    scopus 로고
    • The roles of leptin and adiponectin: A novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology
    • Ding X, Saxena NK, Lin S, Xu A, Srinivasan S, Anania FA. The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology. Am J Pathol 2005; 166: 1655-1669
    • (2005) Am J Pathol , vol.166 , pp. 1655-1669
    • Ding, X.1    Saxena, N.K.2    Lin, S.3    Xu, A.4    Srinivasan, S.5    Anania, F.A.6
  • 133
    • 39549093795 scopus 로고    scopus 로고
    • High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase
    • Adachi M, Brenner DA. High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase. Hepa-tology 2008; 47: 677-685
    • (2008) Hepa-tology , vol.47 , pp. 677-685
    • Adachi, M.1    Brenner, D.A.2
  • 134
    • 77954908071 scopus 로고    scopus 로고
    • Adiponectin activation of AMPK disrupts leptin-mediated hepatic fbrosis via suppressors of cytokine signaling (SOCS-3)
    • Handy JA, Saxena NK, Fu P, Lin S, Mells JE, Gupta NA, Anania FA. Adiponectin activation of AMPK disrupts leptin-mediated hepatic fbrosis via suppressors of cytokine signaling (SOCS-3). J Cell Biochem 2010; 110: 1195-1207
    • (2010) J Cell Biochem , vol.110 , pp. 1195-1207
    • Handy, J.A.1    Saxena, N.K.2    Fu, P.3    Lin, S.4    Mells, J.E.5    Gupta, N.A.6    Anania, F.A.7
  • 136
    • 0036829092 scopus 로고    scopus 로고
    • AGA technical review on nonalcoholic fatty liver disease
    • Sanyal AJ. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 2002; 123: 1705-1725
    • (2002) Gastroenterology , vol.123 , pp. 1705-1725
    • Sanyal, A.J.1
  • 137
    • 72449161164 scopus 로고    scopus 로고
    • Diet and exercise interventions reduce intra-hepatic fat content and improve insulin sensitivity in obese older adults
    • Shah K, Stufflebam A, Hilton TN, Sinacore DR, Klein S, Villareal DT. Diet and exercise interventions reduce intra-hepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring) 2009; 17: 2162-2168
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 2162-2168
    • Shah, K.1    Stufflebam, A.2    Hilton, T.N.3    Sinacore, D.R.4    Klein, S.5    Villareal, D.T.6
  • 140
    • 0025186310 scopus 로고
    • Effect of weight reduction on hepatic abnormalities in overweight patients
    • Palmer M, Schaffner F. Effect of weight reduction on hepatic abnormalities in overweight patients. Gastroenterology 1990; 99: 1408-1413
    • (1990) Gastroenterology , vol.99 , pp. 1408-1413
    • Palmer, M.1    Schaffner, F.2
  • 144
    • 0141532275 scopus 로고    scopus 로고
    • Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosigli-tazone
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosigli-tazone. Hepatology 2003; 38: 1008-1017
    • (2003) Hepatology , vol.38 , pp. 1008-1017
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3    Oliver, D.4    Bacon, B.R.5
  • 145
    • 0037385387 scopus 로고    scopus 로고
    • Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferas-es, hepatic steatosis and body weight in patients with nonalcoholic steatohepatitis
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Spon-seller CA, Hampton K, Bacon BR. Interim results of a pilot study demonstrating the early effects of the PPAR-gamma ligand rosiglitazone on insulin sensitivity, aminotransferas-es, hepatic steatosis and body weight in patients with nonalcoholic steatohepatitis. J Hepatol 2003; 38: 434-440
    • (2003) J Hepatol , vol.38 , pp. 434-440
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3    Spon-Seller, C.A.4    Hampton, K.5    Bacon, B.R.6
  • 146
    • 33745345858 scopus 로고    scopus 로고
    • PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression
    • Sun K, Wang Q, Huang XH. PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression. Acta Pharmacol Sin 2006; 27: 715-723
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 715-723
    • Sun, K.1    Wang, Q.2    Huang, X.H.3
  • 149
    • 70350064027 scopus 로고    scopus 로고
    • Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis
    • Gastaldelli A, Harrison SA, Belfort-Aguilar R, Hardies LJ, Balas B, Schenker S, Cusi K. Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis. Hepatology 2009; 50: 1087-1093
    • (2009) Hepatology , vol.50 , pp. 1087-1093
    • Gastaldelli, A.1    Harrison, S.A.2    Belfort-Aguilar, R.3    Hardies, L.J.4    Balas, B.5    Schenker, S.6    Cusi, K.7
  • 151
    • 34247210640 scopus 로고    scopus 로고
    • Benefcial effects of pentoxifylline on hepatic steatosis, fbro-sis and necroinflammation in patients with non-alcoholic steatohepatitis
    • Satapathy SK, Sakhuja P, Malhotra V, Sharma BC, Sarin SK. Benefcial effects of pentoxifylline on hepatic steatosis, fbro-sis and necroinflammation in patients with non-alcoholic steatohepatitis. J Gastroenterol Hepatol 2007; 22: 634-638
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 634-638
    • Satapathy, S.K.1    Sakhuja, P.2    Malhotra, V.3    Sharma, B.C.4    Sarin, S.K.5
  • 153
    • 33947400987 scopus 로고    scopus 로고
    • Effects of vitamin E treatment on peroxisome proliferator-activated receptor-alpha expression and insulin resistance in patients with non-alcoholic steatohepatitis: Results of a pilot study
    • Yakaryilmaz F, Guliter S, Savas B, Erdem O, Ersoy R, Erden E, Akyol G, Bozkaya H, Ozenirler S. Effects of vitamin E treatment on peroxisome proliferator-activated receptor-alpha expression and insulin resistance in patients with non-alcoholic steatohepatitis: results of a pilot study. Intern Med J 2007; 37: 229-235
    • (2007) Intern Med J , vol.37 , pp. 229-235
    • Yakaryilmaz, F.1    Guliter, S.2    Savas, B.3    Erdem, O.4    Ersoy, R.5    Erden, E.6    Akyol, G.7    Bozkaya, H.8    Ozenirler, S.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.