Translocation of long chain fatty acids across the plasma membrane - Lipid rafts and fatty acid transport proteins

Molecular and Cellular Biochemistry

Volumn 284, Issue 1-2, 2006, Pages 135-140

  Ehehalt, Robert ^a   Füllekrug, Joachim ^a   Pohl, Jürgen ^a   Ring, Axel ^a   Herrmann, Thomas ^a   Stremmel, Wolfgang ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Caveolae; Cholesterol; FAT CD36; FATP; Lipid rafts; Long chain fatty acid uptake

Indexed keywords

BINDING PROTEIN; CAVEOLIN 1; CD36 ANTIGEN; FATTY ACID SYNTHASE; LONG CHAIN FATTY ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; SPHINGOLIPID; FATTY ACID; FATTY ACID TRANSPORTER; MEMBRANE LIPID;

ADIPOCYTE; CATALYSIS; CELL MEMBRANE; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; EUKARYOTIC CELL; FATTY ACID METABOLISM; HUMAN; LIGAND BINDING; LIPID ANALYSIS; LIPID RAFT; LIPID TRANSPORT; MAMMAL CELL; MEMBRANE TRANSPORT; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REVIEW; SMOOTH MUSCLE FIBER; TRANSPORT KINETICS; ANIMAL; DIFFUSION; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ANTIGENS, CD36; BIOLOGICAL TRANSPORT; CELL MEMBRANE; DIFFUSION; FATTY ACID SYNTHETASE COMPLEX; FATTY ACID TRANSPORT PROTEINS; FATTY ACIDS; HUMANS; MEMBRANE LIPIDS; MEMBRANE MICRODOMAINS;

EID: 33745897922     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-005-9034-1     Document Type: Review

References (47)

1. Simopoulos AP: Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr 21: 495-505, 2002
2. Yamashita A, Sugiura T, Waku K: Acyltransferases and transacylases involved in fatty acid remodeling of phospholipids and metabolism of bioactive lipids in mammalian cells. J Biochem (Tokyo) 122: 1-16, 1997
3. Resh MD: Fatty acylatioN of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim Biophys Acta 1451: 1-16, 1999
4. Pegorier JP, Le May C, Girard J: Control of gene expression by fatty acids. J Nutr 134: 2444S-2449S, 2004
5. Grimaldi PA, Knobel SM, Whitesell RR, Abumrad NA: Induction of aP2 gene expression by nonmetabolized long-chain fatty acids. Proc Natl Acad Sci USA 89: 10930-10934, 1992
6. Abumrad NA, Sfeir Z, Connelly MA, Coburn C: Lipid transporters: Membrane transport systems for cholesterol and fatty acids. Curr Opin Clin Nutr Metab Care 3: 255-262, 2000
7. Stahl A: A current review of fatty acid transport proteins (SLC27). Pflugers Arch 447: 722-727, 2004
8. Stremmel W, Pohl L, Ring A, Herrmann T: A new concept of cellular uptake and intracellular trafficking of long-chain fatty acids. Lipids 36: 981-989, 2001
9. Hamilton JA, Guo W, Kamp F: Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins? Mol Cell Biochem 239: 17-23, 2002
10. Hajri T, Abumrad NA: Fatty acid tRansport across membranes: relevance to nutrition and metabolic pathology. Annu Rev Nutr 22: 383-415, 2002
11. Rietveld A, Simons K: The differential miscibility of lipids as the basis for the formation of functional membrane rafts. Biochim Biophys Acta 1376: 467-479, 1998
12. Simons K, Ehehalt R: Cholesterol, lipid rafts, and disease. J Clin Invest 110: 597-603, 2002
13. London E, Brown DA: Insolubility oP lipids in triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts). Biochim Biophys Acta 1508: 182-195, 2000
14. Brown DA, London E: Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 14: 111-136, 1998
15. Harder T, Scheiffele P, Verkade P, Simons K: Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol 141: 929-942, 1998
16. Schuck S, Honsho M, Ekroos K, Shevchenko A, Simons K: Resistance of cell membranes to different detergents. Proc Natl Acad Sci USA 100: 5795-5800, 2003
17. Ehehalt R, Keller P, Haass C, Thiele C, Simons K: Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol 160: 113-123, 2003
18. Pfeiffer A, Bottcher A, Orso E, Kapinsky M, Nagy P, Bodnar A, Spreitzer I, Liebisch G, Drobnik W, Gempel K, Horn M, Holmer S, Hartung T, Multhoff G, Schutz G, Schindler H, Ulmer AJ, Heine H, Stelter F, Schutt C, Rothe G, Szollosi J, Damjanovich S, Schmitz G: Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts. Eur J Immunol 31: 3153-3164, 2001
19. Zeng Y, Tao N, Chung KN, Heuser JE, Lublin DM: Endocytosis of oxidized low density lipoprotein through scavenger receptor CD36 utilizes a lipid raft pathway that does not require caveolin-1. J Biol Chem 278: 45931-45936, 2003
20. Mairhofer M, Steiner M, Mosgoeller W, Prohaska R, Salzer U: Stomatin is a major lipid-raft component of platelet alpha granules. Blood 100: 897-904, 2002
21. Pohl J, Ring A, Korkmaz U, Ehehalt R, Stremmel W: FAT/CD36 Mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts. Mol Biol Cell 16: 24-31, 2005
22. Pohl J, Ring A, Ehehalt R, Schulze-Bergkamen H, Schad A, Verkade P, Stremmel W: Long-chain fatty acid uptake into adipocytes depends on lipid raft function. Biochemistry 43: 4179-4187, 2004
23. Daviet L, Malvoisin E, Wild TF, McGregor JL: Thrombospondin induces dimerization of membrane-bound, but not soluble CD36. Thromb Haemost 78: 897-901, 1997
24. Trigatti BL, Anderson RG, Gerber GE: Identification of caveolin-1 as a fatty acid binding protein. Biochem Biophys Res Commun 255: 34-39, 1999
25. Kurzchalia TV, Parton RG: Membrane microdomains and caveolae. Curr Opin Cell Biol 11: 424-431, 1999
26. Razani B, Combs TP, Wang XB, Frank PG, Park DS, Russell RG, Li M, Tang B, Jelicks LA, Scherer PE, Lisanti MP: Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities. J Biol Chem 277: 8635-8647, 2002
27. Roy S, Luetterforst R, Harding A, Apolloni A, Etheridge M, Stang E, Rolls B, Hancock JF, Parton RG: Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains. Nat Cell Biol 1: 98-105, 1999
28. Pol A, Luetterforst R, Lindsay M, Heino S, Ikonen E, Parton RG: A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance. J Cell Biol 152: 1057-1070, 2001
29. Pol A, Martin S, Fernandez MA, Ferguson C, Carozzi A, Luetterforst R, Enrich C, Parton RG: Dynamic and regulated association of caveolin with lipid bodies: Modulation of lipid body motility and function by a dominant negative mutant. Mol Biol Cell 15: 99-110, 2004
30. Ibrahimi A, Abumrad NA: Role of CD36 in membrane transport of long-chain fatty acids. Curr Opin Clin Nutr Metab Care 5: 139-145, 2002
31. Abumrad N, Coburn C, Ibrahimi A: Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. Biochim Biophys Acta 1441: 4-13, 1999
32. Schaffer JE, Lodish HF: Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell 79: 427-436, 1994
33. Stahl A, Gimeno RE, Tartaglia LA, Lodish HF: Fatty acid transport proteins: A current view of a growing family. Trends Endocrinol Metab 12: 266-273, 2001
34. Hirsch D, Stahl A, Lodish HF: A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci USA 95: 8625-8629, 1998
35. Stahl A, Hirsch DJ, Gimeno RE, Punreddy S, Ge P, Watson N, Patel S, Kotler M, Raimondi A, Tartaglia LA, Lodish HF: Identification of the major intestinal fatty acid transport protein. Mol Cell 4: 299-308, 1999
36. Lewis SE, Listenberger LL, Ory DS, Schaffer JE: Membrane topology of the murine fatty acid transport protein 1. J Biol Chem 276: 37042-37050, 2001
37. Watkins PA, Pevsner J, Steinberg SJ: Human very long-chain acyl-CoA synthetase and two human homologs: Initial characterization and relationship to fatty acid transport protein. Prostaglandins Leukot Essent Fatty Acids 60: 323-328, 1999
38. Pei Z, Fraisl P, Berger J, Jia Z, Forss-Petter S, Watkins PA: Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells. J Biol Chem 279: 54454-54462, 2004
39. Coe NR, Smith AJ, Frohnert BI, Watkins PA, Bernlohr DA: The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase. J Biol Chem 274: 36300-36304, 1999
40. Black PN, Dirusso CC: Transmembrane movement of exogeneous long-chain fatty acids: Proteins, encymes, and vectorial esterification. Microbiol Mol Biol Rev 67: 454-472, 2003
41. Gargiulo CE, Stuhlsatz-Krouper SM, Schaffer JE: Localization of adipocyte long-chain fatty acyl-CoA synthetase at the plasma membrane. J Lipid Res 40: 881-892, 1999
42. Hall AM, Smith AJ, Bernlohr DA: Characterization of the Acyl-CoA synthetase activity of purified murine fatty acid transport protein 1. J Biol Chem 278: 43008-43013, 2003
43. Stuhlsatz-Krouper SM, Bennett NE, Schaffer JE: Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport. J Biol Chem 273: 28642-28650, 1998
44. Steinberg SJ, Mihalik SJ, Kim DG, Cuebas DA, Watkins PA: The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:COA ligase. J Biol Chem 275: 15605-15608, 2000
45. Herrmann T, Buchkremer F, Gosch I, Hall AM, Bernlohr DA, Stremmel W: Mouse fatty acid transport protein 4 (FATP4): Characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase. Gene 270: 31-40, 2001
46. Gimeno RE, Hirsch DJ, Punreddy S, Sun Y, Ortegon AM, Wu H, Daniels T, Stricker-Krongrad A, Lodish HF, Stahl A: Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. J Biol Chem 278: 49512-49516, 2003
47. Herrmann T, van der Hoeven F, Grone HJ, Stewart AF, Langbein L, Kaiser I, Liebisch G, Gosch I, Buchkremer F, Drobnik W, Schmitz G, Stremmel W: Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy. J Cell Biol 161: 1105-1115, 2003