USP17- and SCFβTrCP-regulated degradation of DEC1 controls the DNA damage response

Molecular and Cellular Biology

Volumn 34, Issue 22, 2014, Pages 4177-4185

  Kim, Jihoon ^a   D'Annibale, Sara ^a   Magliozzi, Roberto ^a   Low, Teck Yew ^b,c   Jansen, Petra ^a   Shaltiel, Indra A ^d   Mohammed, Shabaz ^b,c   Heck, Albert J R ^b,c   Medema, Rene H ^d   Guardavaccaro, Daniele ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c NETHERLANDS PROTEOMICS CENTRE   (Netherlands)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; PROTEASOME; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DEC1; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE SCF BETA TRCP; UNCLASSIFIED DRUG; ATM PROTEIN; ATR PROTEIN, HUMAN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; DEC1 PROTEIN, HUMAN; PROTEINASE; TUMOR SUPPRESSOR PROTEIN; USP17L2 PROTEIN, HUMAN;

ARTICLE; CELL FATE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DNA DAMAGE; DNA DAMAGE CHECKPOINT; EMBRYO; GENE SILENCING; HALF LIFE TIME; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; UBIQUITINATION; CELL CYCLE; CELL LINE; DOWN REGULATION; GENETICS; METABOLISM; MUTATION;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CELL CYCLE; CELL LINE; DNA DAMAGE; DOWN-REGULATION; ENDOPEPTIDASES; HUMANS; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION;

EID: 84908868445     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00530-14     Document Type: Article

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