-
1
-
-
0347505003
-
CD28-mediated co-stimulation: a quantitative support for TCR signalling
-
Acuto, O., and F. Michel. 2003. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat. Rev. Immunol. 3:939-951. http:// dx.doi.org/10.1038/nri1248
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
2
-
-
0037564560
-
Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor
-
Acuto, O., S. Mise-Omata, G. Mangino, and F. Michel. 2003. Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor. Immunol. Rev. 192:21-31. http://dx.doi .org/10.1034/j.1600-065X.2003.00034.x
-
(2003)
Immunol. Rev.
, vol.192
, pp. 21-31
-
-
Acuto, O.1
Mise-Omata, S.2
Mangino, G.3
Michel, F.4
-
3
-
-
27144461645
-
Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets
-
Amyes, E., A.J. McMichael, and M.F. Callan. 2005. Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets. J. Immunol. 175:5765-5773.
-
(2005)
J. Immunol.
, vol.175
, pp. 5765-5773
-
-
Amyes, E.1
McMichael, A.J.2
Callan, M.F.3
-
4
-
-
34248569824
-
Identification of their epitope reveals the structural basis for the mechanism of action of the immunosuppressive antibodies basiliximab and daclizumab
-
Binder, M., F.N. Vögtle, S. Michelfelder, F. Müller, G. Illerhaus, S. Sundararajan, R. Mertelsmann, and M. Trepel. 2007. Identification of their epitope reveals the structural basis for the mechanism of action of the immunosuppressive antibodies basiliximab and daclizumab. Cancer Res. 67:3518- 3523. http://dx.doi.org/10.1158/0008-5472.CAN-06-3919
-
(2007)
Cancer Res.
, vol.67
-
-
Binder, M.1
Vögtle, F.N.2
Michelfelder, S.3
Müller, F.4
Illerhaus, G.5
Sundararajan, S.6
Mertelsmann, R.7
Trepel, M.8
-
5
-
-
0029163387
-
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
-
Boise, L.H., A.J. Minn, P.J. Noel, C.H. June, M.A. Accavitti, T. Lindsten, and C.B. Thompson. 1995. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity. 3:87-98. http:// dx.doi.org/10.1016/1074-7613(95)90161-2
-
(1995)
Immunity.
, vol.3
, pp. 87-98
-
-
Boise, L.H.1
Minn, A.J.2
Noel, P.J.3
June, C.H.4
Accavitti, M.A.5
Lindsten, T.6
Thompson, C.B.7
-
6
-
-
0030766777
-
Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells
-
Boudjelal, M., R. Taneja, S. Matsubara, P. Bouillet, P. Dolle, and P. Chambon. 1997. Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells. Genes Dev. 11:2052-2065. http://dx.doi.org/10.1101/gad.11.16.2052
-
(1997)
Genes Dev.
, vol.11
, pp. 2052-2065
-
-
Boudjelal, M.1
Taneja, R.2
Matsubara, S.3
Bouillet, P.4
Dolle, P.5
Chambon, P.6
-
7
-
-
9644270396
-
Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells
-
Bour-Jordan, H., B.L. Salomon, H.L. Thompson, G.L. Szot, M.R. Bernhard, and J.A. Bluestone. 2004. Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. J. Clin. Invest. 114:979-987.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 979-987
-
-
Bour-Jordan, H.1
Salomon, B.L.2
Thompson, H.L.3
Szot, G.L.4
Bernhard, M.R.5
Bluestone, J.A.6
-
8
-
-
79954459308
-
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family
-
Bour-Jordan, H., J.H. Esensten, M. Martinez-Llordella, C. Penaranda, M. Stumpf, and J.A. Bluestone. 2011. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family. Immunol. Rev. 241:180-205. http://dx.doi.org/10.1111/j.1600- 065X.2011.01011.x
-
(2011)
Immunol. Rev.
, vol.241
, pp. 180-205
-
-
Bour-Jordan, H.1
Esensten, J.H.2
Martinez-Llordella, M.3
Penaranda, C.4
Stumpf, M.5
Bluestone, J.A.6
-
9
-
-
33645465526
-
Selective stimulation of T cell subsets with antibody-cytokine immune complexes
-
Boyman, O., M. Kovar, M.P. Rubinstein, C.D. Surh, and J. Sprent. 2006. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science. 311:1924-1927. http://dx.doi.org/10.1126/science.1122927
-
(2006)
Science.
, vol.311
, pp. 1924-1927
-
-
Boyman, O.1
Kovar, M.2
Rubinstein, M.P.3
Surh, C.D.4
Sprent, J.5
-
10
-
-
84863114170
-
CD28 costimulation regulates genome-wide effects on alternative splicing
-
Butte, M.J., S.J. Lee, J. Jesneck, M.E. Keir, W.N. Haining, and A.H. Sharpe. 2012. CD28 costimulation regulates genome-wide effects on alternative splicing. PLoS ONE. 7:e40032. http://dx.doi.org/10.1371/journal .pone.0040032
-
(2012)
PLoS ONE.
, vol.7
-
-
Butte, M.J.1
Lee, S.J.2
Jesneck, J.3
Keir, M.E.4
Haining, W.N.5
Sharpe, A.H.6
-
11
-
-
4644312033
-
The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers
-
Chakrabarti, J., H. Turley, L. Campo, C. Han, A.L. Harris, K.C. Gatter, and S.B. Fox. 2004. The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. Br. J. Cancer. 91:954-958. http://dx.doi.org/10.1038/sj.bjc.6602059
-
(2004)
Br. J. Cancer.
, vol.91
, pp. 954-958
-
-
Chakrabarti, J.1
Turley, H.2
Campo, L.3
Han, C.4
Harris, A.L.5
Gatter, K.C.6
Fox, S.B.7
-
12
-
-
0034601012
-
Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
-
Chu, C.Q., S. Wittmer, and D.K. Dalton. 2000. Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J. Exp. Med. 192:123-128. http://dx.doi.org/10.1084/jem.192.1.123
-
(2000)
J. Exp. Med.
, vol.192
, pp. 123-128
-
-
Chu, C.Q.1
Wittmer, S.2
Dalton, D.K.3
-
13
-
-
79956116032
-
RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
-
Codarri, L., G. Gyülvészi, V. Tosevski, L. Hesske, A. Fontana, L. Magnenat, T. Suter, and B. Becher. 2011. RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat. Immunol. 12:560-567. http:// dx.doi.org/10.1038/ni.2027
-
(2011)
Nat. Immunol.
, vol.12
, pp. 560-567
-
-
Codarri, L.1
Gyülvészi, G.2
Tosevski, V.3
Hesske, L.4
Fontana, A.5
Magnenat, L.6
Suter, T.7
Becher, B.8
-
14
-
-
0037015038
-
Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation
-
Diehn, M., A.A. Alizadeh, O.J. Rando, C.L. Liu, K. Stankunas, D. Botstein, G.R. Crabtree, and P.O. Brown. 2002. Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proc. Natl. Acad. Sci. USA. 99:11796-11801. http://dx.doi.org/ 10.1073/pnas.092284399
-
(2002)
Proc. Natl. Acad. Sci. USA.
, vol.99
, pp. 11796-11801
-
-
Diehn, M.1
Alizadeh, A.A.2
Rando, O.J.3
Liu, C.L.4
Stankunas, K.5
Botstein, D.6
Crabtree, G.R.7
Brown, P.O.8
-
15
-
-
33745062839
-
Control of CD4+ T-cell memory by cytokines and costimulators
-
Dooms, H., and A.K. Abbas. 2006. Control of CD4+ T-cell memory by cytokines and costimulators. Immunol. Rev. 211:23-38. http://dx.doi .org/10.1111/j.0105-2896.2006.00387.x
-
(2006)
Immunol. Rev.
, vol.211
, pp. 23-38
-
-
Dooms, H.1
Abbas, A.K.2
-
16
-
-
0034989361
-
Cascades of transcriptional induction during human lymphocyte activation
-
Ellisen, L.W., R.E. Palmer, R.G. Maki, V.B. Truong, P. Tamayo, J.D. Oliner, and D.A. Haber. 2001. Cascades of transcriptional induction during human lymphocyte activation. Eur. J. Cell Biol. 80:321-328. http://dx.doi .org/10.1078/0171-9335-00162
-
(2001)
Eur. J. Cell Biol.
, vol.80
, pp. 321-328
-
-
Ellisen, L.W.1
Palmer, R.E.2
Maki, R.G.3
Truong, V.B.4
Tamayo, P.5
Oliner, J.D.6
Haber, D.A.7
-
17
-
-
68949102074
-
T-betdeficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function
-
Esensten, J.H., M.R. Lee, L.H. Glimcher, and J.A. Bluestone. 2009. T-betdeficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function. J. Immunol. 183:75-82. http:// dx.doi.org/10.4049/jimmunol.0804154
-
(2009)
J. Immunol.
, vol.183
, pp. 75-82
-
-
Esensten, J.H.1
Lee, M.R.2
Glimcher, L.H.3
Bluestone, J.A.4
-
18
-
-
61749093508
-
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice
-
Haak, S., A.L. Croxford, K. Kreymborg, F.L. Heppner, S. Pouly, B. Becher, and A. Waisman. 2009. IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. J. Clin. Invest. 119:61-69.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 61-69
-
-
Haak, S.1
Croxford, A.L.2
Kreymborg, K.3
Heppner, F.L.4
Pouly, S.5
Becher, B.6
Waisman, A.7
-
19
-
-
0037167847
-
Dec1 and Dec2 are regulators of the mammalian molecular clock
-
Honma, S., T. Kawamoto, Y. Takagi, K. Fujimoto, F. Sato, M. Noshiro, Y. Kato, and K. Honma. 2002. Dec1 and Dec2 are regulators of the mammalian molecular clock. Nature. 419:841-844. http://dx.doi.org/ 10.1038/nature01123
-
(2002)
Nature.
, vol.419
, pp. 841-844
-
-
Honma, S.1
Kawamoto, T.2
Takagi, Y.3
Fujimoto, K.4
Sato, F.5
Noshiro, M.6
Kato, Y.7
Honma, K.8
-
20
-
-
47749120570
-
Regulation of lipogenesis via BHLHB2/ DEC1 and ChREBP feedback looping
-
Iizuka, K., and Y. Horikawa. 2008. Regulation of lipogenesis via BHLHB2/ DEC1 and ChREBP feedback looping. Biochem. Biophys. Res. Commun. 374:95-100. http://dx.doi.org/10.1016/j.bbrc.2008.06.101
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.374
, pp. 95-100
-
-
Iizuka, K.1
Horikawa, Y.2
-
21
-
-
22244434514
-
STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker
-
Ivanova, A., S.Y. Liao, M.I. Lerman, S. Ivanov, and E.J. Stanbridge. 2005. STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker. J. Med. Genet. 42:565-576. http://dx.doi.org/10.1136/jmg.2004.029835
-
(2005)
J. Med. Genet.
, vol.42
, pp. 565-576
-
-
Ivanova, A.1
Liao, S.Y.2
Lerman, M.I.3
Ivanov, S.4
Stanbridge, E.J.5
-
22
-
-
0027491776
-
The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
-
Jain, J., P.G. McCaffrey, Z. Miner, T.K. Kerppola, J.N. Lambert, G.L. Verdine, T. Curran, and A. Rao. 1993. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature. 365:352- 355. http://dx.doi.org/10.1038/365352a0
-
(1993)
Nature.
, vol.365
, pp. 352-355
-
-
Jain, J.1
McCaffrey, P.G.2
Miner, Z.3
Kerppola, T.K.4
Lambert, J.N.5
Verdine, G.L.6
Curran, T.7
Rao, A.8
-
23
-
-
38749154696
-
BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability
-
Jiang, X., F. Tian, Y. Du, N.G. Copeland, N.A. Jenkins, L. Tessarollo, X. Wu, H. Pan, X.Z. Hu, K. Xu, et al. 2008. BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. J. Neurosci. 28:1118-1130. http://dx.doi.org/10.1523/JNEUROSCI.2262-07.2008
-
(2008)
J. Neurosci.
, vol.28
, pp. 1118-1130
-
-
Jiang, X.1
Tian, F.2
Du, Y.3
Copeland, N.G.4
Jenkins, N.A.5
Tessarollo, L.6
Wu, X.7
Pan, H.8
Hu, X.Z.9
Xu, K.10
-
24
-
-
33748135662
-
Molecular signatures induced by interleukin-2 on peripheral blood mononuclear cells and T cell subsets
-
Jin, P., E. Wang, M. Provenzano, S. Deola, S. Selleri, J. Ren, S. Voiculescu, D. Stroncek, M.C. Panelli, and F.M. Marincola. 2006. Molecular signatures induced by interleukin-2 on peripheral blood mononuclear cells and T cell subsets. J. Transl. Med. 4:26. http://dx.doi.org/10.1186/1479-5876-4-26
-
(2006)
J. Transl. Med.
, vol.4
, pp. 26
-
-
Jin, P.1
Wang, E.2
Provenzano, M.3
Deola, S.4
Selleri, S.5
Ren, J.6
Voiculescu, S.7
Stroncek, D.8
Panelli, M.C.9
Marincola, F.M.10
-
25
-
-
0033559545
-
The Jun kinase cascade is responsible for activating the CD28 response element of the IL-2 promoter: proof of cross-talk with the I kappa B kinase cascade
-
Kempiak, S.J., T.S. Hiura, and A.E. Nel. 1999. The Jun kinase cascade is responsible for activating the CD28 response element of the IL-2 promoter: proof of cross-talk with the I kappa B kinase cascade. J. Immunol. 162:3176-3187.
-
(1999)
J.Immunol.
, vol.162
, pp. 3176-3187
-
-
Kempiak, S.J.1
Hiura, T.S.2
Nel, A.E.3
-
26
-
-
57149098568
-
Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts
-
Kon, N., T. Hirota, T. Kawamoto, Y. Kato, T. Tsubota, and Y. Fukada. 2008. Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts. Nat. Cell Biol. 10:1463- 1469. http://dx.doi.org/10.1038/ncb1806
-
(2008)
Nat. Cell Biol.
, vol.10
-
-
Kon, N.1
Hirota, T.2
Kawamoto, T.3
Kato, Y.4
Tsubota, T.5
Fukada, Y.6
-
27
-
-
0029150389
-
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin- 2 expression
-
Köntgen, F., R.J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlinton, and S. Gerondakis. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin- 2 expression. Genes Dev. 9:1965-1977. http://dx.doi.org/10.1101/ gad.9.16.1965
-
(1995)
Genes Dev.
, vol.9
, pp. 1965-1977
-
-
Köntgen, F.1
Grumont, R.J.2
Strasser, A.3
Metcalf, D.4
Li, R.5
Tarlinton, D.6
Gerondakis, S.7
-
28
-
-
0025234426
-
CD28 ligation in T-cell activation: evidence for two signal transduction pathways
-
Ledbetter, J.A., J.B. Imboden, G.L. Schieven, L.S. Grosmaire, P.S. Rabinovitch, T. Lindsten, C.B. Thompson, and C.H. June. 1990. CD28 ligation in T-cell activation: evidence for two signal transduction pathways. Blood. 75:1531-1539.
-
(1990)
Blood.
, vol.75
, pp. 1531-1539
-
-
Ledbetter, J.A.1
Imboden, J.B.2
Schieven, G.L.3
Grosmaire, L.S.4
Rabinovitch, P.S.5
Lindsten, T.6
Thompson, C.B.7
June, C.H.8
-
29
-
-
0029944533
-
CD28/B7 system of T cell costimulation
-
Lenschow, D.J., T.L. Walunas, and J.A. Bluestone. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:233-258. http://dx.doi .org/10.1146/annurev.immunol.14.1.233
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 233-258
-
-
Lenschow, D.J.1
Walunas, T.L.2
Bluestone, J.A.3
-
30
-
-
0037108919
-
Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation
-
Li, Y., H. Zhang, M. Xie, M. Hu, S. Ge, D. Yang, Y. Wan, and B. Yan. 2002. Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation. Biochem. J. 367:413-422. http://dx.doi .org/10.1042/BJ20020514
-
(2002)
Biochem. J.
, vol.367
, pp. 413-422
-
-
Li, Y.1
Zhang, H.2
Xie, M.3
Hu, M.4
Ge, S.5
Yang, D.6
Wan, Y.7
Yan, B.8
-
31
-
-
0037930808
-
DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter
-
Li, Y., M. Xie, X. Song, S. Gragen, K. Sachdeva, Y. Wan, and B. Yan. 2003. DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter. J. Biol. Chem. 278:16899-16907. http://dx.doi.org/10.1074/jbc.M300596200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16899-16907
-
-
Li, Y.1
Xie, M.2
Song, X.3
Gragen, S.4
Sachdeva, K.5
Wan, Y.6
Yan, B.7
-
32
-
-
33744925726
-
The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter
-
Li, Y., M. Xie, J. Yang, D. Yang, R. Deng, Y. Wan, and B. Yan. 2006. The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter. Oncogene. 25:3296-3306. http://dx.doi.org/10.1038/sj.onc .1209363
-
(2006)
Oncogene.
, vol.25
, pp. 3296-3306
-
-
Li, Y.1
Xie, M.2
Yang, J.3
Yang, D.4
Deng, R.5
Wan, Y.6
Yan, B.7
-
33
-
-
65349185047
-
The clinical utility of inhibiting CD28- mediated costimulation
-
Linsley, P.S., and S.G. Nadler. 2009. The clinical utility of inhibiting CD28- mediated costimulation. Immunol. Rev. 229:307-321. http://dx.doi .org/10.1111/j.1600-065X.2009.00780.x
-
(2009)
Immunol. Rev.
, vol.229
, pp. 307-321
-
-
Linsley, P.S.1
Nadler, S.G.2
-
34
-
-
77952937323
-
Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling
-
Liu, Z., Z. Li, K. Mao, J. Zou, Y. Wang, Z. Tao, G. Lin, L. Tian, Y. Ji, X. Wu, et al. 2009. Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling. J. Immunol. 183:6320-6329. http://dx.doi .org/10.4049/jimmunol.0900975
-
(2009)
J. Immunol.
, vol.183
, pp. 6320-6329
-
-
Liu, Z.1
Li, Z.2
Mao, K.3
Zou, J.4
Wang, Y.5
Tao, Z.6
Lin, G.7
Tian, L.8
Ji, Y.9
Wu, X.10
-
35
-
-
33746357544
-
Regulatory T cells in the periphery
-
Lohr, J., B. Knoechel, and A.K. Abbas. 2006. Regulatory T cells in the periphery. Immunol. Rev. 212:149-162. http://dx.doi.org/10.1111/ j.0105-2896.2006.00414.x
-
(2006)
Immunol. Rev.
, vol.212
, pp. 149-162
-
-
Lohr, J.1
Knoechel, B.2
Abbas, A.K.3
-
36
-
-
0037077135
-
Transcriptional mechanisms underlying lymphocyte tolerance
-
Macián, F., F. García-Cózar, S.H. Im, H.F. Horton, M.C. Byrne, and A. Rao. 2002. Transcriptional mechanisms underlying lymphocyte tolerance. Cell. 109:719-731. http://dx.doi.org/10.1016/S0092-8674(02)00767-5
-
(2002)
Cell.
, vol.109
, pp. 719-731
-
-
Macián, F.1
García-Cózar, F.2
Im, S.H.3
Horton, H.F.4
Byrne, M.C.5
Rao, A.6
-
37
-
-
1942437466
-
CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters
-
Marinari, B., A. Costanzo, V. Marzano, E. Piccolella, and L. Tuosto. 2004. CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters. Proc. Natl. Acad. Sci. USA. 101:6098-6103. http://dx.doi.org/ 10.1073/pnas.0308688101
-
(2004)
Proc. Natl. Acad. Sci. USA.
, vol.101
, pp. 6098-6103
-
-
Marinari, B.1
Costanzo, A.2
Marzano, V.3
Piccolella, E.4
Tuosto, L.5
-
38
-
-
0035476518
-
Granulocyte macrophage colonystimulating factor: A new putative therapeutic target in multiple sclerosis
-
McQualter, J.L., R. Darwiche, C. Ewing, M. Onuki, T.W. Kay, J.A. Hamilton, H.H. Reid, and C.C. Bernard. 2001. Granulocyte macrophage colonystimulating factor: A new putative therapeutic target in multiple sclerosis. J. Exp. Med. 194:873-882. http://dx.doi.org/10.1084/jem.194.7.873
-
(2001)
J. Exp. Med.
, vol.194
, pp. 873-882
-
-
McQualter, J.L.1
Darwiche, R.2
Ewing, C.3
Onuki, M.4
Kay, T.W.5
Hamilton, J.A.6
Reid, H.H.7
Bernard, C.C.8
-
39
-
-
0037033095
-
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
-
Miyazaki, K., T. Kawamoto, K. Tanimoto, M. Nishiyama, H. Honda, and Y. Kato. 2002. Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J. Biol. Chem. 277:47014-47021. http://dx.doi.org/10.1074/jbc.M204938200
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47014-47021
-
-
Miyazaki, K.1
Kawamoto, T.2
Tanimoto, K.3
Nishiyama, M.4
Honda, H.5
Kato, Y.6
-
40
-
-
78650670349
-
The role of the basic helixloop- helix transcription factor Dec1 in the regulatory T cells
-
Miyazaki, K., M. Miyazaki, Y. Guo, N. Yamasaki, M. Kanno, Z. Honda, H. Oda, H. Kawamoto, and H. Honda. 2010. The role of the basic helixloop- helix transcription factor Dec1 in the regulatory T cells. J. Immunol. 185:7330-7339. http://dx.doi.org/10.4049/jimmunol.1001381
-
(2010)
J. Immunol.
, vol.185
, pp. 7330-7339
-
-
Miyazaki, K.1
Miyazaki, M.2
Guo, Y.3
Yamasaki, N.4
Kanno, M.5
Honda, Z.6
Oda, H.7
Kawamoto, H.8
Honda, H.9
-
41
-
-
64749110932
-
Tracking epitope-specific T cells
-
Moon, J.J., H.H. Chu, J. Hataye, A.J. Pagán, M. Pepper, J.B. McLachlan, T. Zell, and M.K. Jenkins. 2009. Tracking epitope-specific T cells. Nat. Protoc. 4:565-581. http://dx.doi.org/10.1038/nprot.2009.9
-
(2009)
Nat. Protoc.
, vol.4
, pp. 565-581
-
-
Moon, J.J.1
Chu, H.H.2
Hataye, J.3
Pagán, A.J.4
Pepper, M.5
McLachlan, J.B.6
Zell, T.7
Jenkins, M.K.8
-
42
-
-
0030006733
-
CD28 costimulation prevents cell death during primary T cell activation
-
Noel, P.J., L.H. Boise, J.M. Green, and C.B. Thompson. 1996. CD28 costimulation prevents cell death during primary T cell activation. J. Immunol. 157:636-642.
-
(1996)
J. Immunol.
, vol.157
, pp. 636-642
-
-
Noel, P.J.1
Boise, L.H.2
Green, J.M.3
Thompson, C.B.4
-
43
-
-
0033561661
-
CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis
-
Oliveira-dos-Santos, A.J., A. Ho, Y. Tada, J.J. Lafaille, S. Tonegawa, T.W. Mak, and J.M. Penninger. 1999. CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis. J. Immunol. 162:4490-4495.
-
(1999)
J. Immunol.
, vol.162
, pp. 4490-4495
-
-
Oliveira-dos-Santos, A.J.1
Ho, A.2
Tada, Y.3
Lafaille, J.J.4
Tonegawa, S.5
Mak, T.W.6
Penninger, J.M.7
-
44
-
-
58549094896
-
The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells
-
Park, S.G., J. Schulze-Luehrman, M.S. Hayden, N. Hashimoto, W. Ogawa, M. Kasuga, and S. Ghosh. 2009. The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells. Nat. Immunol. 10:158-166. http://dx.doi.org/10.1038/ ni.1687
-
(2009)
Nat. Immunol.
, vol.10
, pp. 158-166
-
-
Park, S.G.1
Schulze-Luehrman, J.2
Hayden, M.S.3
Hashimoto, N.4
Ogawa, W.5
Kasuga, M.6
Ghosh, S.7
-
45
-
-
0028814279
-
Role of B7:CD28/CTLA-4 in the induction of chronic relapsing experimental allergic encephalomyelitis
-
Perrin, P.J., D. Scott, L. Quigley, P.S. Albert, O. Feder, G.S. Gray, R. Abe, C.H. June, and M.K. Racke. 1995. Role of B7:CD28/CTLA-4 in the induction of chronic relapsing experimental allergic encephalomyelitis. J. Immunol. 154:1481-1490.
-
(1995)
J. Immunol.
, vol.154
, pp. 1481-1490
-
-
Perrin, P.J.1
Scott, D.2
Quigley, L.3
Albert, P.S.4
Feder, O.5
Gray, G.S.6
Abe, R.7
June, C.H.8
Racke, M.K.9
-
46
-
-
0033179230
-
Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis
-
Perrin, P.J., C.H. June, J.H. Maldonado, R.B. Ratts, and M.K. Racke. 1999. Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis. J. Immunol. 163:1704-1710.
-
(1999)
J. Immunol.
, vol.163
, pp. 1704-1710
-
-
Perrin, P.J.1
June, C.H.2
Maldonado, J.H.3
Ratts, R.B.4
Racke, M.K.5
-
47
-
-
81755184012
-
Cytokines and effector T cell subsets causing autoimmune CNS disease
-
Petermann, F., and T. Korn. 2011. Cytokines and effector T cell subsets causing autoimmune CNS disease. FEBS Lett. 585:3747-3757. http:// dx.doi.org/10.1016/j.febslet.2011.03.064
-
(2011)
FEBS Lett.
, vol.585
, pp. 3747-3757
-
-
Petermann, F.1
Korn, T.2
-
48
-
-
33846018916
-
GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis
-
Ponomarev, E.D., L.P. Shriver, K. Maresz, J. Pedras-Vasconcelos, D. Verthelyi, and B.N. Dittel. 2007. GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis. J. Immunol. 178:39-48.
-
(2007)
J. Immunol.
, vol.178
, pp. 39-48
-
-
Ponomarev, E.D.1
Shriver, L.P.2
Maresz, K.3
Pedras-Vasconcelos, J.4
Verthelyi, D.5
Dittel, B.N.6
-
49
-
-
62749201002
-
Expansion of human regulatory T-cells from patients with type 1 diabetes
-
Putnam, A.L., T.M. Brusko, M.R. Lee, W. Liu, G.L. Szot, T. Ghosh, M.A. Atkinson, and J.A. Bluestone. 2009. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes. 58:652-662. http://dx.doi .org/10.2337/db08-1168
-
(2009)
Diabetes.
, vol.58
, pp. 652-662
-
-
Putnam, A.L.1
Brusko, T.M.2
Lee, M.R.3
Liu, W.4
Szot, G.L.5
Ghosh, T.6
Atkinson, M.A.7
Bluestone, J.A.8
-
50
-
-
2642513869
-
Individual-specific variation of gene expression in peripheral blood leukocytes
-
Radich, J.P., M. Mao, S. Stepaniants, M. Biery, J. Castle, T. Ward, G. Schimmack, S. Kobayashi, M. Carleton, J. Lampe, and P.S. Linsley. 2004. Individual-specific variation of gene expression in peripheral blood leukocytes. Genomics. 83:980-988. http://dx.doi.org/10.1016/ j.ygeno.2003.12.013
-
(2004)
Genomics.
, vol.83
, pp. 980-988
-
-
Radich, J.P.1
Mao, M.2
Stepaniants, S.3
Biery, M.4
Castle, J.5
Ward, T.6
Schimmack, G.7
Kobayashi, S.8
Carleton, M.9
Lampe, J.10
Linsley, P.S.11
-
51
-
-
0346195644
-
c-Rel is required for chromatin remodeling across the IL-2 gene promoter
-
Rao, S., S. Gerondakis, D. Woltring, and M.F. Shannon. 2003. c-Rel is required for chromatin remodeling across the IL-2 gene promoter. J. Immunol. 170:3724-3731.
-
(2003)
J. Immunol.
, vol.170
, pp. 3724-3731
-
-
Rao, S.1
Gerondakis, S.2
Woltring, D.3
Shannon, M.F.4
-
52
-
-
0037015055
-
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
-
Riley, J.L., M. Mao, S. Kobayashi, M. Biery, J. Burchard, G. Cavet, B.P. Gregson, C.H. June, and P.S. Linsley. 2002. Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors. Proc. Natl. Acad. Sci. USA. 99:11790-11795. http://dx.doi.org/10.1073/ pnas.162359999
-
(2002)
Proc. Natl. Acad. Sci. USA.
, vol.99
, pp. 11790-11795
-
-
Riley, J.L.1
Mao, M.2
Kobayashi, S.3
Biery, M.4
Burchard, J.5
Cavet, G.6
Gregson, B.P.7
June, C.H.8
Linsley, P.S.9
-
53
-
-
0029986943
-
Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia
-
Robertson, M.J., K.J. Cochran, C. Cameron, J.M. Le, R. Tantravahi, and J. Ritz. 1996. Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia. Exp. Hematol. 24:406-415.
-
(1996)
Exp. Hematol.
, vol.24
, pp. 406-415
-
-
Robertson, M.J.1
Cochran, K.J.2
Cameron, C.3
Le, J.M.4
Tantravahi, R.5
Ritz, J.6
-
54
-
-
50649102521
-
Disturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant mice
-
Rossner, M.J., H. Oster, S.P. Wichert, L. Reinecke, M.C. Wehr, J. Reinecke, G. Eichele, R. Taneja, and K.A. Nave. 2008. Disturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant mice. PLoS ONE. 3:e2762. http://dx.doi.org/10.1371/journal.pone.0002762
-
(2008)
PLoS ONE.
, vol.3
-
-
Rossner, M.J.1
Oster, H.2
Wichert, S.P.3
Reinecke, L.4
Wehr, M.C.5
Reinecke, J.6
Eichele, G.7
Taneja, R.8
Nave, K.A.9
-
55
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon, B., D.J. Lenschow, L. Rhee, N. Ashourian, B. Singh, A. Sharpe, and J.A. Bluestone. 2000. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 12:431-440. http://dx.doi.org/ 10.1016/S1074-7613(00)80195-8
-
(2000)
Immunity.
, vol.12
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
Ashourian, N.4
Singh, B.5
Sharpe, A.6
Bluestone, J.A.7
-
56
-
-
10344237020
-
Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways
-
Sanchez-Lockhart, M., E. Marin, B. Graf, R. Abe, Y. Harada, C.E. Sedwick, and J. Miller. 2004. Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways. J. Immunol. 173:7120-7124.
-
(2004)
J. Immunol.
, vol.173
, pp. 7120-7124
-
-
Sanchez-Lockhart, M.1
Marin, E.2
Graf, B.3
Abe, R.4
Harada, Y.5
Sedwick, C.E.6
Miller, J.7
-
57
-
-
33645785083
-
NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity
-
Sánchez-Valdepeñas, C., A.G. Martín, P. Ramakrishnan, D. Wallach, and M. Fresno. 2006. NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. J. Immunol. 176:4666-4674.
-
(2006)
J. Immunol.
, vol.176
, pp. 4666-4674
-
-
Sánchez-Valdepeñas, C.1
Martín, A.G.2
Ramakrishnan, P.3
Wallach, D.4
Fresno, M.5
-
58
-
-
0042389785
-
T cell anergy
-
Schwartz, R.H. 2003. T cell anergy. Annu. Rev. Immunol. 21:305-334. http:// dx.doi.org/10.1146/annurev.immunol.21.120601.141110
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 305-334
-
-
Schwartz, R.H.1
-
59
-
-
0036484220
-
The B7-CD28 superfamily
-
Sharpe, A.H., and G.J. Freeman. 2002. The B7-CD28 superfamily. Nat. Rev. Immunol. 2:116-126. http://dx.doi.org/10.1038/nri727
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 116-126
-
-
Sharpe, A.H.1
Freeman, G.J.2
-
60
-
-
0035175548
-
Defective T cell activation and autoimmune disorder in Stra13-deficient mice
-
Sun, H., B. Lu, R.Q. Li, R.A. Flavell, and R. Taneja. 2001. Defective T cell activation and autoimmune disorder in Stra13-deficient mice. Nat. Immunol. 2:1040-1047. http://dx.doi.org/10.1038/ni721
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1040-1047
-
-
Sun, H.1
Lu, B.2
Li, R.Q.3
Flavell, R.A.4
Taneja, R.5
-
61
-
-
57049125546
-
CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/ Gads axis
-
Takeda, K., Y. Harada, R. Watanabe, Y. Inutake, S. Ogawa, K. Onuki, S. Kagaya, K. Tanabe, H. Kishimoto, and R. Abe. 2008. CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/ Gads axis. Int. Immunol. 20:1507-1515. http://dx.doi.org/10.1093/ intimm/dxn108
-
(2008)
Int. Immunol.
, vol.20
, pp. 1507-1515
-
-
Takeda, K.1
Harada, Y.2
Watanabe, R.3
Inutake, Y.4
Ogawa, S.5
Onuki, K.6
Kagaya, S.7
Tanabe, K.8
Kishimoto, H.9
Abe, R.10
-
62
-
-
2442546516
-
Identification of transcription factor binding sites upstream of human genes regulated by the phosphatidylinositol 3-kinase and MEK/ERK signaling pathways
-
Tullai, J.W., M.E. Schaffer, S. Mullenbrock, S. Kasif, and G.M. Cooper. 2004. Identification of transcription factor binding sites upstream of human genes regulated by the phosphatidylinositol 3-kinase and MEK/ERK signaling pathways. J. Biol. Chem. 279:20167-20177. http://dx.doi.org/ 10.1074/jbc.M309260200
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20167-20177
-
-
Tullai, J.W.1
Schaffer, M.E.2
Mullenbrock, S.3
Kasif, S.4
Cooper, G.M.5
-
63
-
-
84872551703
-
Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells
-
Wakamatsu, E., D. Mathis, and C. Benoist. 2013. Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells. Proc. Natl. Acad. Sci. USA. 110:1023-1028. http://dx.doi.org/ 10.1073/pnas.1220688110
-
(2013)
Proc. Natl. Acad. Sci. USA.
, vol.110
, pp. 1023-1028
-
-
Wakamatsu, E.1
Mathis, D.2
Benoist, C.3
-
64
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang, R., C.P. Dillon, L.Z. Shi, S. Milasta, R. Carter, D. Finkelstein, L.L. McCormick, P. Fitzgerald, H. Chi, J. Munger, and D.R. Green. 2011. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity. 35:871-882. http://dx.doi .org/10.1016/j.immuni.2011.09.021
-
(2011)
Immunity.
, vol.35
, pp. 871-882
-
-
Wang, R.1
Dillon, C.P.2
Shi, L.Z.3
Milasta, S.4
Carter, R.5
Finkelstein, D.6
McCormick, L.L.7
Fitzgerald, P.8
Chi, H.9
Munger, J.10
Green, D.R.11
-
65
-
-
84855588476
-
Developing and activated T cell survival depends on differential signaling pathways to regulate anti-apoptotic Bcl-x(L)
-
Wang, R., H. Xie, Z. Huang, W. Shang, and Z. Sun. 2012. Developing and activated T cell survival depends on differential signaling pathways to regulate anti-apoptotic Bcl-x(L). Clin. Dev. Immunol. 2012:632837.
-
(2012)
Clin. Dev. Immunol.
, vol.2012
, pp. 632837
-
-
Wang, R.1
Xie, H.2
Huang, Z.3
Shang, W.4
Sun, Z.5
-
66
-
-
77958153013
-
Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma
-
Wang, W., C. Reiser-Erkan, C.W. Michalski, M.C. Raggi, L. Quan, Z. Yupei, H. Friess, M. Erkan, and J. Kleeff. 2010. Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Biochem. Biophys. Res. Commun. 401:422-428. http://dx.doi.org/10.1016/j.bbrc.2010.09.070
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.401
, pp. 422-428
-
-
Wang, W.1
Reiser-Erkan, C.2
Michalski, C.W.3
Raggi, M.C.4
Quan, L.5
Yupei, Z.6
Friess, H.7
Erkan, M.8
Kleeff, J.9
-
67
-
-
65549091509
-
In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
-
Webster, K.E., S. Walters, R.E. Kohler, T. Mrkvan, O. Boyman, C.D. Surh, S.T. Grey, and J. Sprent. 2009. In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J. Exp. Med. 206:751-760. http://dx.doi.org/10.1084/jem.20082824
-
(2009)
J. Exp. Med.
, vol.206
, pp. 751-760
-
-
Webster, K.E.1
Walters, S.2
Kohler, R.E.3
Mrkvan, T.4
Boyman, O.5
Surh, C.D.6
Grey, S.T.7
Sprent, J.8
-
68
-
-
0037452790
-
Individuality and variation in gene expression patterns in human blood
-
Whitney, A.R., M. Diehn, S.J. Popper, A.A. Alizadeh, J.C. Boldrick, D.A. Relman, and P.O. Brown. 2003. Individuality and variation in gene expression patterns in human blood. Proc. Natl. Acad. Sci. USA. 100:1896- 1901. http://dx.doi.org/10.1073/pnas.252784499
-
(2003)
Proc. Natl. Acad. Sci. USA.
, vol.100
-
-
Whitney, A.R.1
Diehn, M.2
Popper, S.J.3
Alizadeh, A.A.4
Boldrick, J.C.5
Relman, D.A.6
Brown, P.O.7
-
69
-
-
70449707113
-
Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment
-
Yang, X.O., P. Angkasekwinai, J. Zhu, J. Peng, Z. Liu, R. Nurieva, X. Liu, Y. Chung, S.H. Chang, B. Sun, and C. Dong. 2009. Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment. Nat. Immunol. 10:1260-1266. http://dx.doi.org/10.1038/ni.1821
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1260-1266
-
-
Yang, X.O.1
Angkasekwinai, P.2
Zhu, J.3
Peng, J.4
Liu, Z.5
Nurieva, R.6
Liu, X.7
Chung, Y.8
Chang, S.H.9
Sun, B.10
Dong, C.11
-
70
-
-
69249120887
-
The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer
-
Zheng, Y., Y. Jia, Y. Wang, M. Wang, B. Li, X. Shi, X. Ma, D. Xiao, and Y. Sun. 2009. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer. OMICS. 13:301-306. http://dx.doi.org/10.1089/omi.2009.0014
-
(2009)
OMICS.
, vol.13
, pp. 301-306
-
-
Zheng, Y.1
Jia, Y.2
Wang, Y.3
Wang, M.4
Li, B.5
Shi, X.6
Ma, X.7
Xiao, D.8
Sun, Y.9
|