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Volumn 210, Issue 8, 2013, Pages 1603-1619

CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DEC1; TRANSCRIPTOME; UNCLASSIFIED DRUG;

EID: 84884230330     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122387     Document Type: Article
Times cited : (81)

References (70)
  • 1
    • 0347505003 scopus 로고    scopus 로고
    • CD28-mediated co-stimulation: a quantitative support for TCR signalling
    • Acuto, O., and F. Michel. 2003. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat. Rev. Immunol. 3:939-951. http:// dx.doi.org/10.1038/nri1248
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 939-951
    • Acuto, O.1    Michel, F.2
  • 2
    • 0037564560 scopus 로고    scopus 로고
    • Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor
    • Acuto, O., S. Mise-Omata, G. Mangino, and F. Michel. 2003. Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor. Immunol. Rev. 192:21-31. http://dx.doi .org/10.1034/j.1600-065X.2003.00034.x
    • (2003) Immunol. Rev. , vol.192 , pp. 21-31
    • Acuto, O.1    Mise-Omata, S.2    Mangino, G.3    Michel, F.4
  • 3
    • 27144461645 scopus 로고    scopus 로고
    • Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets
    • Amyes, E., A.J. McMichael, and M.F. Callan. 2005. Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets. J. Immunol. 175:5765-5773.
    • (2005) J. Immunol. , vol.175 , pp. 5765-5773
    • Amyes, E.1    McMichael, A.J.2    Callan, M.F.3
  • 4
    • 34248569824 scopus 로고    scopus 로고
    • Identification of their epitope reveals the structural basis for the mechanism of action of the immunosuppressive antibodies basiliximab and daclizumab
    • Binder, M., F.N. Vögtle, S. Michelfelder, F. Müller, G. Illerhaus, S. Sundararajan, R. Mertelsmann, and M. Trepel. 2007. Identification of their epitope reveals the structural basis for the mechanism of action of the immunosuppressive antibodies basiliximab and daclizumab. Cancer Res. 67:3518- 3523. http://dx.doi.org/10.1158/0008-5472.CAN-06-3919
    • (2007) Cancer Res. , vol.67
    • Binder, M.1    Vögtle, F.N.2    Michelfelder, S.3    Müller, F.4    Illerhaus, G.5    Sundararajan, S.6    Mertelsmann, R.7    Trepel, M.8
  • 5
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • Boise, L.H., A.J. Minn, P.J. Noel, C.H. June, M.A. Accavitti, T. Lindsten, and C.B. Thompson. 1995. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity. 3:87-98. http:// dx.doi.org/10.1016/1074-7613(95)90161-2
    • (1995) Immunity. , vol.3 , pp. 87-98
    • Boise, L.H.1    Minn, A.J.2    Noel, P.J.3    June, C.H.4    Accavitti, M.A.5    Lindsten, T.6    Thompson, C.B.7
  • 6
    • 0030766777 scopus 로고    scopus 로고
    • Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells
    • Boudjelal, M., R. Taneja, S. Matsubara, P. Bouillet, P. Dolle, and P. Chambon. 1997. Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells. Genes Dev. 11:2052-2065. http://dx.doi.org/10.1101/gad.11.16.2052
    • (1997) Genes Dev. , vol.11 , pp. 2052-2065
    • Boudjelal, M.1    Taneja, R.2    Matsubara, S.3    Bouillet, P.4    Dolle, P.5    Chambon, P.6
  • 8
    • 79954459308 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family
    • Bour-Jordan, H., J.H. Esensten, M. Martinez-Llordella, C. Penaranda, M. Stumpf, and J.A. Bluestone. 2011. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family. Immunol. Rev. 241:180-205. http://dx.doi.org/10.1111/j.1600- 065X.2011.01011.x
    • (2011) Immunol. Rev. , vol.241 , pp. 180-205
    • Bour-Jordan, H.1    Esensten, J.H.2    Martinez-Llordella, M.3    Penaranda, C.4    Stumpf, M.5    Bluestone, J.A.6
  • 9
    • 33645465526 scopus 로고    scopus 로고
    • Selective stimulation of T cell subsets with antibody-cytokine immune complexes
    • Boyman, O., M. Kovar, M.P. Rubinstein, C.D. Surh, and J. Sprent. 2006. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science. 311:1924-1927. http://dx.doi.org/10.1126/science.1122927
    • (2006) Science. , vol.311 , pp. 1924-1927
    • Boyman, O.1    Kovar, M.2    Rubinstein, M.P.3    Surh, C.D.4    Sprent, J.5
  • 10
    • 84863114170 scopus 로고    scopus 로고
    • CD28 costimulation regulates genome-wide effects on alternative splicing
    • Butte, M.J., S.J. Lee, J. Jesneck, M.E. Keir, W.N. Haining, and A.H. Sharpe. 2012. CD28 costimulation regulates genome-wide effects on alternative splicing. PLoS ONE. 7:e40032. http://dx.doi.org/10.1371/journal .pone.0040032
    • (2012) PLoS ONE. , vol.7
    • Butte, M.J.1    Lee, S.J.2    Jesneck, J.3    Keir, M.E.4    Haining, W.N.5    Sharpe, A.H.6
  • 11
    • 4644312033 scopus 로고    scopus 로고
    • The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers
    • Chakrabarti, J., H. Turley, L. Campo, C. Han, A.L. Harris, K.C. Gatter, and S.B. Fox. 2004. The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. Br. J. Cancer. 91:954-958. http://dx.doi.org/10.1038/sj.bjc.6602059
    • (2004) Br. J. Cancer. , vol.91 , pp. 954-958
    • Chakrabarti, J.1    Turley, H.2    Campo, L.3    Han, C.4    Harris, A.L.5    Gatter, K.C.6    Fox, S.B.7
  • 12
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
    • Chu, C.Q., S. Wittmer, and D.K. Dalton. 2000. Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J. Exp. Med. 192:123-128. http://dx.doi.org/10.1084/jem.192.1.123
    • (2000) J. Exp. Med. , vol.192 , pp. 123-128
    • Chu, C.Q.1    Wittmer, S.2    Dalton, D.K.3
  • 13
    • 79956116032 scopus 로고    scopus 로고
    • RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
    • Codarri, L., G. Gyülvészi, V. Tosevski, L. Hesske, A. Fontana, L. Magnenat, T. Suter, and B. Becher. 2011. RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat. Immunol. 12:560-567. http:// dx.doi.org/10.1038/ni.2027
    • (2011) Nat. Immunol. , vol.12 , pp. 560-567
    • Codarri, L.1    Gyülvészi, G.2    Tosevski, V.3    Hesske, L.4    Fontana, A.5    Magnenat, L.6    Suter, T.7    Becher, B.8
  • 15
    • 33745062839 scopus 로고    scopus 로고
    • Control of CD4+ T-cell memory by cytokines and costimulators
    • Dooms, H., and A.K. Abbas. 2006. Control of CD4+ T-cell memory by cytokines and costimulators. Immunol. Rev. 211:23-38. http://dx.doi .org/10.1111/j.0105-2896.2006.00387.x
    • (2006) Immunol. Rev. , vol.211 , pp. 23-38
    • Dooms, H.1    Abbas, A.K.2
  • 17
    • 68949102074 scopus 로고    scopus 로고
    • T-betdeficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function
    • Esensten, J.H., M.R. Lee, L.H. Glimcher, and J.A. Bluestone. 2009. T-betdeficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function. J. Immunol. 183:75-82. http:// dx.doi.org/10.4049/jimmunol.0804154
    • (2009) J. Immunol. , vol.183 , pp. 75-82
    • Esensten, J.H.1    Lee, M.R.2    Glimcher, L.H.3    Bluestone, J.A.4
  • 20
    • 47749120570 scopus 로고    scopus 로고
    • Regulation of lipogenesis via BHLHB2/ DEC1 and ChREBP feedback looping
    • Iizuka, K., and Y. Horikawa. 2008. Regulation of lipogenesis via BHLHB2/ DEC1 and ChREBP feedback looping. Biochem. Biophys. Res. Commun. 374:95-100. http://dx.doi.org/10.1016/j.bbrc.2008.06.101
    • (2008) Biochem. Biophys. Res. Commun. , vol.374 , pp. 95-100
    • Iizuka, K.1    Horikawa, Y.2
  • 21
    • 22244434514 scopus 로고    scopus 로고
    • STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker
    • Ivanova, A., S.Y. Liao, M.I. Lerman, S. Ivanov, and E.J. Stanbridge. 2005. STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker. J. Med. Genet. 42:565-576. http://dx.doi.org/10.1136/jmg.2004.029835
    • (2005) J. Med. Genet. , vol.42 , pp. 565-576
    • Ivanova, A.1    Liao, S.Y.2    Lerman, M.I.3    Ivanov, S.4    Stanbridge, E.J.5
  • 22
    • 0027491776 scopus 로고
    • The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
    • Jain, J., P.G. McCaffrey, Z. Miner, T.K. Kerppola, J.N. Lambert, G.L. Verdine, T. Curran, and A. Rao. 1993. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature. 365:352- 355. http://dx.doi.org/10.1038/365352a0
    • (1993) Nature. , vol.365 , pp. 352-355
    • Jain, J.1    McCaffrey, P.G.2    Miner, Z.3    Kerppola, T.K.4    Lambert, J.N.5    Verdine, G.L.6    Curran, T.7    Rao, A.8
  • 25
    • 0033559545 scopus 로고    scopus 로고
    • The Jun kinase cascade is responsible for activating the CD28 response element of the IL-2 promoter: proof of cross-talk with the I kappa B kinase cascade
    • Kempiak, S.J., T.S. Hiura, and A.E. Nel. 1999. The Jun kinase cascade is responsible for activating the CD28 response element of the IL-2 promoter: proof of cross-talk with the I kappa B kinase cascade. J. Immunol. 162:3176-3187.
    • (1999) J.Immunol. , vol.162 , pp. 3176-3187
    • Kempiak, S.J.1    Hiura, T.S.2    Nel, A.E.3
  • 26
    • 57149098568 scopus 로고    scopus 로고
    • Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts
    • Kon, N., T. Hirota, T. Kawamoto, Y. Kato, T. Tsubota, and Y. Fukada. 2008. Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts. Nat. Cell Biol. 10:1463- 1469. http://dx.doi.org/10.1038/ncb1806
    • (2008) Nat. Cell Biol. , vol.10
    • Kon, N.1    Hirota, T.2    Kawamoto, T.3    Kato, Y.4    Tsubota, T.5    Fukada, Y.6
  • 27
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin- 2 expression
    • Köntgen, F., R.J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlinton, and S. Gerondakis. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin- 2 expression. Genes Dev. 9:1965-1977. http://dx.doi.org/10.1101/ gad.9.16.1965
    • (1995) Genes Dev. , vol.9 , pp. 1965-1977
    • Köntgen, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlinton, D.6    Gerondakis, S.7
  • 29
    • 0029944533 scopus 로고    scopus 로고
    • CD28/B7 system of T cell costimulation
    • Lenschow, D.J., T.L. Walunas, and J.A. Bluestone. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:233-258. http://dx.doi .org/10.1146/annurev.immunol.14.1.233
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 233-258
    • Lenschow, D.J.1    Walunas, T.L.2    Bluestone, J.A.3
  • 30
    • 0037108919 scopus 로고    scopus 로고
    • Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation
    • Li, Y., H. Zhang, M. Xie, M. Hu, S. Ge, D. Yang, Y. Wan, and B. Yan. 2002. Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation. Biochem. J. 367:413-422. http://dx.doi .org/10.1042/BJ20020514
    • (2002) Biochem. J. , vol.367 , pp. 413-422
    • Li, Y.1    Zhang, H.2    Xie, M.3    Hu, M.4    Ge, S.5    Yang, D.6    Wan, Y.7    Yan, B.8
  • 31
    • 0037930808 scopus 로고    scopus 로고
    • DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter
    • Li, Y., M. Xie, X. Song, S. Gragen, K. Sachdeva, Y. Wan, and B. Yan. 2003. DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter. J. Biol. Chem. 278:16899-16907. http://dx.doi.org/10.1074/jbc.M300596200
    • (2003) J. Biol. Chem. , vol.278 , pp. 16899-16907
    • Li, Y.1    Xie, M.2    Song, X.3    Gragen, S.4    Sachdeva, K.5    Wan, Y.6    Yan, B.7
  • 32
    • 33744925726 scopus 로고    scopus 로고
    • The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter
    • Li, Y., M. Xie, J. Yang, D. Yang, R. Deng, Y. Wan, and B. Yan. 2006. The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter. Oncogene. 25:3296-3306. http://dx.doi.org/10.1038/sj.onc .1209363
    • (2006) Oncogene. , vol.25 , pp. 3296-3306
    • Li, Y.1    Xie, M.2    Yang, J.3    Yang, D.4    Deng, R.5    Wan, Y.6    Yan, B.7
  • 33
    • 65349185047 scopus 로고    scopus 로고
    • The clinical utility of inhibiting CD28- mediated costimulation
    • Linsley, P.S., and S.G. Nadler. 2009. The clinical utility of inhibiting CD28- mediated costimulation. Immunol. Rev. 229:307-321. http://dx.doi .org/10.1111/j.1600-065X.2009.00780.x
    • (2009) Immunol. Rev. , vol.229 , pp. 307-321
    • Linsley, P.S.1    Nadler, S.G.2
  • 34
    • 77952937323 scopus 로고    scopus 로고
    • Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling
    • Liu, Z., Z. Li, K. Mao, J. Zou, Y. Wang, Z. Tao, G. Lin, L. Tian, Y. Ji, X. Wu, et al. 2009. Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling. J. Immunol. 183:6320-6329. http://dx.doi .org/10.4049/jimmunol.0900975
    • (2009) J. Immunol. , vol.183 , pp. 6320-6329
    • Liu, Z.1    Li, Z.2    Mao, K.3    Zou, J.4    Wang, Y.5    Tao, Z.6    Lin, G.7    Tian, L.8    Ji, Y.9    Wu, X.10
  • 35
    • 33746357544 scopus 로고    scopus 로고
    • Regulatory T cells in the periphery
    • Lohr, J., B. Knoechel, and A.K. Abbas. 2006. Regulatory T cells in the periphery. Immunol. Rev. 212:149-162. http://dx.doi.org/10.1111/ j.0105-2896.2006.00414.x
    • (2006) Immunol. Rev. , vol.212 , pp. 149-162
    • Lohr, J.1    Knoechel, B.2    Abbas, A.K.3
  • 36
    • 0037077135 scopus 로고    scopus 로고
    • Transcriptional mechanisms underlying lymphocyte tolerance
    • Macián, F., F. García-Cózar, S.H. Im, H.F. Horton, M.C. Byrne, and A. Rao. 2002. Transcriptional mechanisms underlying lymphocyte tolerance. Cell. 109:719-731. http://dx.doi.org/10.1016/S0092-8674(02)00767-5
    • (2002) Cell. , vol.109 , pp. 719-731
    • Macián, F.1    García-Cózar, F.2    Im, S.H.3    Horton, H.F.4    Byrne, M.C.5    Rao, A.6
  • 37
    • 1942437466 scopus 로고    scopus 로고
    • CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters
    • Marinari, B., A. Costanzo, V. Marzano, E. Piccolella, and L. Tuosto. 2004. CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters. Proc. Natl. Acad. Sci. USA. 101:6098-6103. http://dx.doi.org/ 10.1073/pnas.0308688101
    • (2004) Proc. Natl. Acad. Sci. USA. , vol.101 , pp. 6098-6103
    • Marinari, B.1    Costanzo, A.2    Marzano, V.3    Piccolella, E.4    Tuosto, L.5
  • 38
    • 0035476518 scopus 로고    scopus 로고
    • Granulocyte macrophage colonystimulating factor: A new putative therapeutic target in multiple sclerosis
    • McQualter, J.L., R. Darwiche, C. Ewing, M. Onuki, T.W. Kay, J.A. Hamilton, H.H. Reid, and C.C. Bernard. 2001. Granulocyte macrophage colonystimulating factor: A new putative therapeutic target in multiple sclerosis. J. Exp. Med. 194:873-882. http://dx.doi.org/10.1084/jem.194.7.873
    • (2001) J. Exp. Med. , vol.194 , pp. 873-882
    • McQualter, J.L.1    Darwiche, R.2    Ewing, C.3    Onuki, M.4    Kay, T.W.5    Hamilton, J.A.6    Reid, H.H.7    Bernard, C.C.8
  • 39
    • 0037033095 scopus 로고    scopus 로고
    • Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
    • Miyazaki, K., T. Kawamoto, K. Tanimoto, M. Nishiyama, H. Honda, and Y. Kato. 2002. Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J. Biol. Chem. 277:47014-47021. http://dx.doi.org/10.1074/jbc.M204938200
    • (2002) J. Biol. Chem. , vol.277 , pp. 47014-47021
    • Miyazaki, K.1    Kawamoto, T.2    Tanimoto, K.3    Nishiyama, M.4    Honda, H.5    Kato, Y.6
  • 40
    • 78650670349 scopus 로고    scopus 로고
    • The role of the basic helixloop- helix transcription factor Dec1 in the regulatory T cells
    • Miyazaki, K., M. Miyazaki, Y. Guo, N. Yamasaki, M. Kanno, Z. Honda, H. Oda, H. Kawamoto, and H. Honda. 2010. The role of the basic helixloop- helix transcription factor Dec1 in the regulatory T cells. J. Immunol. 185:7330-7339. http://dx.doi.org/10.4049/jimmunol.1001381
    • (2010) J. Immunol. , vol.185 , pp. 7330-7339
    • Miyazaki, K.1    Miyazaki, M.2    Guo, Y.3    Yamasaki, N.4    Kanno, M.5    Honda, Z.6    Oda, H.7    Kawamoto, H.8    Honda, H.9
  • 42
    • 0030006733 scopus 로고    scopus 로고
    • CD28 costimulation prevents cell death during primary T cell activation
    • Noel, P.J., L.H. Boise, J.M. Green, and C.B. Thompson. 1996. CD28 costimulation prevents cell death during primary T cell activation. J. Immunol. 157:636-642.
    • (1996) J. Immunol. , vol.157 , pp. 636-642
    • Noel, P.J.1    Boise, L.H.2    Green, J.M.3    Thompson, C.B.4
  • 44
    • 58549094896 scopus 로고    scopus 로고
    • The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells
    • Park, S.G., J. Schulze-Luehrman, M.S. Hayden, N. Hashimoto, W. Ogawa, M. Kasuga, and S. Ghosh. 2009. The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells. Nat. Immunol. 10:158-166. http://dx.doi.org/10.1038/ ni.1687
    • (2009) Nat. Immunol. , vol.10 , pp. 158-166
    • Park, S.G.1    Schulze-Luehrman, J.2    Hayden, M.S.3    Hashimoto, N.4    Ogawa, W.5    Kasuga, M.6    Ghosh, S.7
  • 46
    • 0033179230 scopus 로고    scopus 로고
    • Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis
    • Perrin, P.J., C.H. June, J.H. Maldonado, R.B. Ratts, and M.K. Racke. 1999. Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis. J. Immunol. 163:1704-1710.
    • (1999) J. Immunol. , vol.163 , pp. 1704-1710
    • Perrin, P.J.1    June, C.H.2    Maldonado, J.H.3    Ratts, R.B.4    Racke, M.K.5
  • 47
    • 81755184012 scopus 로고    scopus 로고
    • Cytokines and effector T cell subsets causing autoimmune CNS disease
    • Petermann, F., and T. Korn. 2011. Cytokines and effector T cell subsets causing autoimmune CNS disease. FEBS Lett. 585:3747-3757. http:// dx.doi.org/10.1016/j.febslet.2011.03.064
    • (2011) FEBS Lett. , vol.585 , pp. 3747-3757
    • Petermann, F.1    Korn, T.2
  • 48
    • 33846018916 scopus 로고    scopus 로고
    • GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis
    • Ponomarev, E.D., L.P. Shriver, K. Maresz, J. Pedras-Vasconcelos, D. Verthelyi, and B.N. Dittel. 2007. GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis. J. Immunol. 178:39-48.
    • (2007) J. Immunol. , vol.178 , pp. 39-48
    • Ponomarev, E.D.1    Shriver, L.P.2    Maresz, K.3    Pedras-Vasconcelos, J.4    Verthelyi, D.5    Dittel, B.N.6
  • 51
    • 0346195644 scopus 로고    scopus 로고
    • c-Rel is required for chromatin remodeling across the IL-2 gene promoter
    • Rao, S., S. Gerondakis, D. Woltring, and M.F. Shannon. 2003. c-Rel is required for chromatin remodeling across the IL-2 gene promoter. J. Immunol. 170:3724-3731.
    • (2003) J. Immunol. , vol.170 , pp. 3724-3731
    • Rao, S.1    Gerondakis, S.2    Woltring, D.3    Shannon, M.F.4
  • 53
    • 0029986943 scopus 로고    scopus 로고
    • Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia
    • Robertson, M.J., K.J. Cochran, C. Cameron, J.M. Le, R. Tantravahi, and J. Ritz. 1996. Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia. Exp. Hematol. 24:406-415.
    • (1996) Exp. Hematol. , vol.24 , pp. 406-415
    • Robertson, M.J.1    Cochran, K.J.2    Cameron, C.3    Le, J.M.4    Tantravahi, R.5    Ritz, J.6
  • 55
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • Salomon, B., D.J. Lenschow, L. Rhee, N. Ashourian, B. Singh, A. Sharpe, and J.A. Bluestone. 2000. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 12:431-440. http://dx.doi.org/ 10.1016/S1074-7613(00)80195-8
    • (2000) Immunity. , vol.12 , pp. 431-440
    • Salomon, B.1    Lenschow, D.J.2    Rhee, L.3    Ashourian, N.4    Singh, B.5    Sharpe, A.6    Bluestone, J.A.7
  • 56
    • 10344237020 scopus 로고    scopus 로고
    • Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways
    • Sanchez-Lockhart, M., E. Marin, B. Graf, R. Abe, Y. Harada, C.E. Sedwick, and J. Miller. 2004. Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways. J. Immunol. 173:7120-7124.
    • (2004) J. Immunol. , vol.173 , pp. 7120-7124
    • Sanchez-Lockhart, M.1    Marin, E.2    Graf, B.3    Abe, R.4    Harada, Y.5    Sedwick, C.E.6    Miller, J.7
  • 57
    • 33645785083 scopus 로고    scopus 로고
    • NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity
    • Sánchez-Valdepeñas, C., A.G. Martín, P. Ramakrishnan, D. Wallach, and M. Fresno. 2006. NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. J. Immunol. 176:4666-4674.
    • (2006) J. Immunol. , vol.176 , pp. 4666-4674
    • Sánchez-Valdepeñas, C.1    Martín, A.G.2    Ramakrishnan, P.3    Wallach, D.4    Fresno, M.5
  • 58
    • 0042389785 scopus 로고    scopus 로고
    • T cell anergy
    • Schwartz, R.H. 2003. T cell anergy. Annu. Rev. Immunol. 21:305-334. http:// dx.doi.org/10.1146/annurev.immunol.21.120601.141110
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 305-334
    • Schwartz, R.H.1
  • 59
    • 0036484220 scopus 로고    scopus 로고
    • The B7-CD28 superfamily
    • Sharpe, A.H., and G.J. Freeman. 2002. The B7-CD28 superfamily. Nat. Rev. Immunol. 2:116-126. http://dx.doi.org/10.1038/nri727
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 116-126
    • Sharpe, A.H.1    Freeman, G.J.2
  • 60
    • 0035175548 scopus 로고    scopus 로고
    • Defective T cell activation and autoimmune disorder in Stra13-deficient mice
    • Sun, H., B. Lu, R.Q. Li, R.A. Flavell, and R. Taneja. 2001. Defective T cell activation and autoimmune disorder in Stra13-deficient mice. Nat. Immunol. 2:1040-1047. http://dx.doi.org/10.1038/ni721
    • (2001) Nat. Immunol. , vol.2 , pp. 1040-1047
    • Sun, H.1    Lu, B.2    Li, R.Q.3    Flavell, R.A.4    Taneja, R.5
  • 62
    • 2442546516 scopus 로고    scopus 로고
    • Identification of transcription factor binding sites upstream of human genes regulated by the phosphatidylinositol 3-kinase and MEK/ERK signaling pathways
    • Tullai, J.W., M.E. Schaffer, S. Mullenbrock, S. Kasif, and G.M. Cooper. 2004. Identification of transcription factor binding sites upstream of human genes regulated by the phosphatidylinositol 3-kinase and MEK/ERK signaling pathways. J. Biol. Chem. 279:20167-20177. http://dx.doi.org/ 10.1074/jbc.M309260200
    • (2004) J. Biol. Chem. , vol.279 , pp. 20167-20177
    • Tullai, J.W.1    Schaffer, M.E.2    Mullenbrock, S.3    Kasif, S.4    Cooper, G.M.5
  • 63
    • 84872551703 scopus 로고    scopus 로고
    • Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells
    • Wakamatsu, E., D. Mathis, and C. Benoist. 2013. Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells. Proc. Natl. Acad. Sci. USA. 110:1023-1028. http://dx.doi.org/ 10.1073/pnas.1220688110
    • (2013) Proc. Natl. Acad. Sci. USA. , vol.110 , pp. 1023-1028
    • Wakamatsu, E.1    Mathis, D.2    Benoist, C.3
  • 65
    • 84855588476 scopus 로고    scopus 로고
    • Developing and activated T cell survival depends on differential signaling pathways to regulate anti-apoptotic Bcl-x(L)
    • Wang, R., H. Xie, Z. Huang, W. Shang, and Z. Sun. 2012. Developing and activated T cell survival depends on differential signaling pathways to regulate anti-apoptotic Bcl-x(L). Clin. Dev. Immunol. 2012:632837.
    • (2012) Clin. Dev. Immunol. , vol.2012 , pp. 632837
    • Wang, R.1    Xie, H.2    Huang, Z.3    Shang, W.4    Sun, Z.5
  • 67
    • 65549091509 scopus 로고    scopus 로고
    • In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
    • Webster, K.E., S. Walters, R.E. Kohler, T. Mrkvan, O. Boyman, C.D. Surh, S.T. Grey, and J. Sprent. 2009. In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J. Exp. Med. 206:751-760. http://dx.doi.org/10.1084/jem.20082824
    • (2009) J. Exp. Med. , vol.206 , pp. 751-760
    • Webster, K.E.1    Walters, S.2    Kohler, R.E.3    Mrkvan, T.4    Boyman, O.5    Surh, C.D.6    Grey, S.T.7    Sprent, J.8
  • 70
    • 69249120887 scopus 로고    scopus 로고
    • The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer
    • Zheng, Y., Y. Jia, Y. Wang, M. Wang, B. Li, X. Shi, X. Ma, D. Xiao, and Y. Sun. 2009. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer. OMICS. 13:301-306. http://dx.doi.org/10.1089/omi.2009.0014
    • (2009) OMICS. , vol.13 , pp. 301-306
    • Zheng, Y.1    Jia, Y.2    Wang, Y.3    Wang, M.4    Li, B.5    Shi, X.6    Ma, X.7    Xiao, D.8    Sun, Y.9


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