Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division

Journal of Biological Chemistry

Volumn 289, Issue 11, 2014, Pages 7730-7737

  D'Annibale, Sara ^a   Kim, Jihoon ^a   Magliozzi, Roberto ^a   Low, Teck Yew ^b,c   Mohammed, Shabaz ^b,c   Heck, Albert J R ^b,c   Guardavaccaro, Daniele ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c NETHERLANDS PROTEOMICS CENTRE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; CHEMICAL ACTIVATION; TRANSCRIPTION FACTORS;

BASIC HELIX LOOP HELIXES; CELL DIVISION CYCLE; CELLULAR PROLIFERATIONS; DNA DAMAGE RESPONSE; ENHANCER-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; HUMAN MALIGNANCIES; MULTIPOLAR SPINDLES;

GENE EXPRESSION REGULATION;

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BINDING PROTEIN; PROTEASOME; TRANSCRIPTION FACTOR ACTIVATING ENHANCER BINDING PROTEIN 4; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DIVISION; CELL PROLIFERATION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA DAMAGE; EPITHELIAL MESENCHYMAL TRANSITION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MITOSIS; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RNA INTERFERENCE; UBIQUITINATION; UPREGULATION;

BETATRCP; CELL CYCLE; E3 UBIQUITIN LIGASE; MITOSIS; PROTEIN DEGRADATION; TFAP4; UBIQUITIN;

CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; DNA-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; G2 PHASE; GENE EXPRESSION REGULATION; HEK293 CELLS; HELA CELLS; HUMANS; MASS SPECTROMETRY; MICROSCOPY, FLUORESCENCE; MITOSIS; MUTATION; PHOSPHORYLATION; PLASMIDS; PROTEASOME ENDOPEPTIDASE COMPLEX; SKP CULLIN F-BOX PROTEIN LIGASES; TRANSCRIPTION FACTORS;

EID: 84896292915     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.549535     Document Type: Article

References (27)

1. Jung, P., and Hermeking, H. (2009) The c-MYC-AP4-p21 cascade. Cell Cycle 8, 982-989
2. Jackstadt R., Röh, S., Neumann, J., Jung, P., Hoffmann, R., Horst, D., Berens, C., Bornkamm, G. W., Kirchner, T., Menssen, A., and Hermeking, H. (2013) AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer. J. Exp. Med. 210, 1331-1350
3. Jung, P., Menssen, A., Mayr, D., and Hermeking, H (2008) AP4 encodes a c-MYC-inducible repressor of p21. Proc. Natl. Acad. Sci. U.S.A. 105, 15046-15051
4. Hu, B. S., Zhao, G., Yu, H. F., Chen, K., Dong, J. H., and Tan, J. W. (2013) High expression of AP-4 predicts poor prognosis for hepatocellular carcinoma after curative hepatectomy. Tumour Biol. 34, 271-276
5. Xinghua, L., Bo, Z., Yan, G., Lei, W., Changyao, W., Qi, L., Lin, Y., Kaixiong, T., Guobin, W., and Jianying, C. (2012) The overexpression of AP-4 as a prognostic indicator for gastric carcinoma. Med. Oncol. 29, 871-877
6. Frescas, D., and Pagano, M. (2008) Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer. Nat. Rev. Cancer 8, 438-449 (Pubitemid 351744963)
7. Cardozo, T., and Pagano, M. (2004) The SCF ubiquitin ligase: insights into a molecular machine. Nat. Rev. Mol. Cell Biol. 5, 739-751 (Pubitemid 39208183)
8. Nakayama, K. I., and Nakayama, K. (2006) Ubiquitin ligases: cell-cycle control and cancer. Nat. Rev. Cancer 6, 369-381
9. Guardavaccaro, D., Kudo, Y., Boulaire, J., Barchi, M., Busino, L., Donzelli, M., Margottin-Goguet, F., Jackson, P. K., Yamasaki, L., and Pagano, M. (2003) Control of meiotic and mitotic progression by the F box protein β-Trcp1 in vivo. Dev. Cell 4, 799-812 (Pubitemid 36676033)
10. Ping, Z., Lim, R., Bashir, T., Pagano, M., and Guardavaccaro, D. (2012) APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit. Cell Cycle 11, 1999-2005
11. Guardavaccaro, D., Frescas, D., Dorrello, N. V., Peschiaroli, A., Multani, A. S., Cardozo, T., Lasorella, A., Iavarone, A., Chang, S., Hernando, E., and Pagano, M. (2008) Control of chromosome stability by the β-TrCP-REST-Mad2 axis. Nature 452, 365-369 (Pubitemid 351430786)
12. Dorrello, N. V., Peschiaroli, A., Guardavaccaro, D., Colburn, N. H., Sherman, N. E., and Pagano, M. (2006) S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 314, 467-471 (Pubitemid 44628968)
13. Shevchenko, A., Wilm, M., Vorm, O., and Mann, M. (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68, 850-858
14. Raijmakers, R., Berkers, C. R., de Jong, A., Ovaa, H., Heck, A. J., and Mohammed, S. (2008) Automated online sequential isotope labeling for protein quantitation applied to proteasome tissue-specific diversity. Mol. Cell Proteomics 7, 1755-1762
15. Cox, J., and Mann, M. (2008) MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat. Biotechnol. 26, 1367-1372
16. Peschiaroli, A., Dorrello, N. V., Guardavaccaro, D., Venere, M., Halazonetis, T., Sherman, N. E., and Pagano, M. (2006) SCFßTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol. Cell 23, 319-329 (Pubitemid 44128849)
17. Magliozzi, R., Low, T. Y., Weijts, B. G., Cheng, T., Spanjaard, E., Mohammed, S., van Veen, A., Ovaa, H., de Rooij, J., Zwartkruis, F. J., Bos, J. L., de Bruin, A., Heck, A. J., and Guardavaccaro, D. (2013) Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2. Dev. Cell 27, 574-585
18. Kruiswijk, F., Yuniati, L., Magliozzi, R., Low, T. Y., Lim, R., Bolder, R., Mohammed, S., Proud, C. G., Heck, A. J., Pagano, M., and Guardavaccaro, D. (2012) Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress. Sci. Signal. 5: ra40
19. Frese, C. K., Altelaar, A. F., Hennrich, M. L., Nolting, D., Zeller, M., Griep-Raming, J., Heck, A. J., and Mohammed, S. (2011) Improved peptide identification by targeted fragmentation using CID, HCD and ETD on an LTQ-Orbitrap Velos. J. Proteome Res. 10, 2377-2388
20. Swaney, D. L., McAlister, G. C., and Coon, J. J. (2008) Decision tree-driven tandem mass spectrometry for shotgun proteomics. Nat. Methods 5, 959-964
21. Taus, T., Köcher, T., Pichler, P., Paschke, C., Schmidt, A., Henrich, C., and Mechtler, K. (2011) Universal and confident phosphorylation site localization using phosphoRS. J. Proteome Res. 10, 5354-5362
22. Wu, G., Xu, G., Schulman, B. A., Jeffrey, P. D., Harper, J. W., and Pavletich, N. P. (2003) Structure of a β-TrCP1-Skp1-β-catenin complex: destruction motif binding and lysine specificity of the SCF(β-TrCP1) ubiquitin ligase. Mol. Cell 11, 1445-1456 (Pubitemid 36776532)
23. Watanabe, N., Arai, H., Nishihara, Y., Taniguchi, M., Watanabe, N., Hunter, T., and Osada, H. (2004) M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFβ-TrCP. Proc. Natl. Acad. Sci. U.S.A. 101, 4419-4424 (Pubitemid 38437427)
24. Kanemori, Y., Uto, K., and Sagata, N. (2005) β-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases. Proc. Natl. Acad. Sci. U.S.A. 102, 6279-6284 (Pubitemid 40617434)
25. Busino, L., Donzelli, M., Chiesa, M., Guardavaccaro, D., Ganoth, D., Dorrello, N. V., Hershko, A., Pagano, M., and Draetta, G. F. (2003) Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage. Nature 426, 87-91 (Pubitemid 37432546)
26. Sakaue-Sawano, A., Kurokawa, H., Morimura, T., Hanyu, A., Hama, H., Osawa, H., Kashiwagi, S., Fukami, K., Miyata, T., Miyoshi, H., Imamura, T., Ogawa, M., Masai, H., and Miyawaki, A. (2008) Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell 132, 487-498 (Pubitemid 351191996)
27. Janssen, A., van der Burg, M., Szuhai, K., Kops, G. J., and Medema, R. H. (2011) Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science 333, 1895-1898