Glial TLR4 signaling does not contribute to opioid-induced depression of respiration

Journal of Applied Physiology

Volumn 117, Issue 8, 2014, Pages 857-868

  Zwicker, Jennifer D ^a   Zhang, Yong ^a   Ren, Jun ^a   Hutchinson, Mark R ^b   Rice, Kenner C ^c   Watkins, Linda R ^d   Greer, John J ^a   Funk, Gregory D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Opioid; Pre B tzinger complex; Rat; Respiratory depression; Toll like receptor

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FENTANYL; MINOCYCLINE; MU OPIATE RECEPTOR; NALOXONE; NARCOTIC ANALGESIC AGENT; TLR4 PROTEIN, RAT; TOLL LIKE RECEPTOR 4;

AGONISTS; ANIMAL; BREATHING; CHEMICALLY INDUCED; DRUG EFFECTS; FEMALE; GLIA; MALE; MEDULLA OBLONGATA; METABOLISM; PATHOLOGY; PHYSIOLOGY; RAT; RESPIRATORY FAILURE; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANALGESICS, OPIOID; ANIMALS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; FEMALE; FENTANYL; MALE; MEDULLA OBLONGATA; MINOCYCLINE; NALOXONE; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; RESPIRATION; RESPIRATORY INSUFFICIENCY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84908566867     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00534.2014     Document Type: Article

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