Clinically relevant infusion rates of μ-opioid agonist remifentanil cause bradypnea in decerebrate dogs but not via direct effects in the pre-Bötzinger complex region

Journal of Neurophysiology

Volumn 103, Issue 1, 2010, Pages 409-418

  Mustapic, Sanda ^a,b   Radocaj, Tomislav ^a,b   Sanchez, Antonio ^a,b   Dogas, Zoran ^d   Stucke, Astrid G ^a,c   Hopp, Francis A ^a,b   Stuth, Eckehard A E ^a,c   Zuperku, Edward J ^a,b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Children's Hospital of Wisconsin   (United States)

^d UNIVERSITY OF SPLIT   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GLUTAMATE RECEPTOR AGONIST; HOMOCYSTEIC ACID; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXONE; OPIATE ANTAGONIST; REMIFENTANIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYPNEA; BRAIN REGION; BREATHING PATTERN; BREATHING RATE; DECEREBRATION; DOG; DRUG SAFETY; INFUSION RATE; MEDULLA OBLONGATA; MICROPIPETTE; NERVE CONDUCTION; NONHUMAN; PHRENIC NERVE; PREBOTZINGER COMPLEX; PRIORITY JOURNAL; TACHYPNEA;

ACTION POTENTIALS; ANALGESICS, OPIOID; ANIMALS; BRAIN STEM; DECEREBRATE STATE; DOGS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; EXCITATORY AMINO ACID AGONISTS; FEMALE; FUNCTIONAL LATERALITY; HOMOCYSTEINE; MALE; MICROINJECTIONS; NALOXONE; NARCOTIC ANTAGONISTS; NEURONS; PHRENIC NERVE; PIPERIDINES; RESPIRATORY RATE; TIME FACTORS;

EID: 74049097521     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00188.2009     Document Type: Article

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