메뉴 건너뛰기




Volumn 5, Issue 18, 2014, Pages 8107-8122

TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; TRANSCRIPTION FACTOR E2F1; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; E2F1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEASOME; TP53 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

EID: 84908012088     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2440     Document Type: Article
Times cited : (27)

References (62)
  • 1
    • 0032483562 scopus 로고    scopus 로고
    • DNA damage and checkpoint pathways: molecular anatomy and interactions with repair
    • Weinert T. DNA damage and checkpoint pathways: molecular anatomy and interactions with repair. Cell. 1998; 94(5):555-558.
    • (1998) Cell , vol.94 , Issue.5 , pp. 555-558
    • Weinert, T.1
  • 2
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan G and Littlewood T. A matter of life and cell death. Science. 1998; 281(5381):1317-1322.
    • (1998) Science , vol.281 , Issue.5381 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 3
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • Vogelstein B, Lane D and Levine AJ. Surfing the p53 network. Nature. 2000; 408(6810):307-310.
    • (2000) Nature , vol.408 , Issue.6810 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 4
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson SP and Bartek J. The DNA-damage response in human biology and disease. Nature. 2009; 461(7267): 1071-1078.
    • (2009) Nature , vol.461 , Issue.7267 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 5
    • 84856019858 scopus 로고    scopus 로고
    • The DNA damage response and cancer therapy
    • Lord CJ and Ashworth A. The DNA damage response and cancer therapy. Nature. 2012; 481(7381):287-294.
    • (2012) Nature , vol.481 , Issue.7381 , pp. 287-294
    • Lord, C.J.1    Ashworth, A.2
  • 8
    • 0031564954 scopus 로고    scopus 로고
    • p73 is a human p53-related protein that can induce apoptosis
    • Jost CA, Marin MC and Kaelin WG Jr. p73 is a human p53-related protein that can induce apoptosis. Nature. 1997; 389(6647):191-194.
    • (1997) Nature , vol.389 , Issue.6647 , pp. 191-194
    • Jost, C.A.1    Marin, M.C.2    Kaelin Jr., W.G.3
  • 10
    • 17444390129 scopus 로고    scopus 로고
    • Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family
    • Flores ER, Sengupta S, Miller JB, Newman JJ, Bronson R, Crowley D, Yang A, McKeon F and Jacks T. Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell. 2005; 7(4):363-373.
    • (2005) Cancer Cell , vol.7 , Issue.4 , pp. 363-373
    • Flores, E.R.1    Sengupta, S.2    Miller, J.B.3    Newman, J.J.4    Bronson, R.5    Crowley, D.6    Yang, A.7    McKeon, F.8    Jacks, T.9
  • 13
    • 0034647718 scopus 로고    scopus 로고
    • An anti-apoptotic role for the p53 family member, p73, during developmental neuron death
    • Pozniak CD, Radinovic S, Yang A, McKeon F, Kaplan DR and Miller FD. An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science. 2000; 289(5477):304-306.
    • (2000) Science , vol.289 , Issue.5477 , pp. 304-306
    • Pozniak, C.D.1    Radinovic, S.2    Yang, A.3    McKeon, F.4    Kaplan, D.R.5    Miller, F.D.6
  • 14
    • 0037041392 scopus 로고    scopus 로고
    • p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
    • Flores ER, Tsai KY, Crowley D, Sengupta S, Yang A, McKeon F and Jacks T. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature. 2002; 416(6880):560-564.
    • (2002) Nature , vol.416 , Issue.6880 , pp. 560-564
    • Flores, E.R.1    Tsai, K.Y.2    Crowley, D.3    Sengupta, S.4    Yang, A.5    McKeon, F.6    Jacks, T.7
  • 16
    • 79953282304 scopus 로고    scopus 로고
    • NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling
    • Biton S and Ashkenazi A. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling. Cell. 2011; 145(1):92-103.
    • (2011) Cell , vol.145 , Issue.1 , pp. 92-103
    • Biton, S.1    Ashkenazi, A.2
  • 17
    • 34247211554 scopus 로고    scopus 로고
    • The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage
    • Wang P, Yu J and Zhang L. The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage. Proc Natl Acad Sci U S A. 2007; 104(10):4054-4059.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.10 , pp. 4054-4059
    • Wang, P.1    Yu, J.2    Zhang, L.3
  • 18
    • 0037452759 scopus 로고    scopus 로고
    • PUMA mediates the apoptotic response to p53 in colorectal cancer cells
    • Yu J, Wang Z, Kinzler KW, Vogelstein B and Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci U S A. 2003; 100(4): 1931-1936.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.4 , pp. 1931-1936
    • Yu, J.1    Wang, Z.2    Kinzler, K.W.3    Vogelstein, B.4    Zhang, L.5
  • 19
    • 0035265823 scopus 로고    scopus 로고
    • PUMA induces the rapid apoptosis of colorectal cancer cells
    • Yu J, Zhang L, Hwang PM, Kinzler KW and Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell. 2001; 7(3):673-682.
    • (2001) Mol Cell , vol.7 , Issue.3 , pp. 673-682
    • Yu, J.1    Zhang, L.2    Hwang, P.M.3    Kinzler, K.W.4    Vogelstein, B.5
  • 22
    • 0033666776 scopus 로고    scopus 로고
    • Role of the p53-homologue p73 in E2F1-induced apoptosis
    • Stiewe T and Putzer BM. Role of the p53-homologue p73 in E2F1-induced apoptosis. Nat Genet. 2000; 26(4):464-469.
    • (2000) Nat Genet , vol.26 , Issue.4 , pp. 464-469
    • Stiewe, T.1    Putzer, B.M.2
  • 24
    • 79956144655 scopus 로고    scopus 로고
    • Following cytochrome c release, autophagy is inhibited during chemotherapyinduced apoptosis by caspase 8-mediated cleavage of Beclin 1
    • Li H, Wang P, Sun Q, Ding WX, Yin XM, Sobol RW, Stolz DB, Yu J and Zhang L. Following cytochrome c release, autophagy is inhibited during chemotherapyinduced apoptosis by caspase 8-mediated cleavage of Beclin 1. Cancer Res. 2011; 71(10):3625-3634.
    • (2011) Cancer Res , vol.71 , Issue.10 , pp. 3625-3634
    • Li, H.1    Wang, P.2    Sun, Q.3    Ding, W.X.4    Yin, X.M.5    Sobol, R.W.6    Stolz, D.B.7    Yu, J.8    Zhang, L.9
  • 27
    • 30344450404 scopus 로고    scopus 로고
    • p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
    • Rocco JW, Leong CO, Kuperwasser N, DeYoung MP and Ellisen LW. p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis. Cancer Cell. 2006; 9(1):45-56.
    • (2006) Cancer Cell , vol.9 , Issue.1 , pp. 45-56
    • Rocco, J.W.1    Leong, C.O.2    Kuperwasser, N.3    DeYoung, M.P.4    Ellisen, L.W.5
  • 28
    • 77954274181 scopus 로고    scopus 로고
    • Lysine methylation regulates E2F1-induced cell death
    • Kontaki H and Talianidis I. Lysine methylation regulates E2F1-induced cell death. Mol Cell. 2010; 39(1):152-160.
    • (2010) Mol Cell , vol.39 , Issue.1 , pp. 152-160
    • Kontaki, H.1    Talianidis, I.2
  • 30
    • 78649684224 scopus 로고    scopus 로고
    • PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01
    • Dudgeon C, Wang P, Sun X, Peng R, Sun Q, Yu J and Zhang L. PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01. Mol Cancer Ther. 2010; 9(11):2893-2902.
    • (2010) Mol Cancer Ther , vol.9 , Issue.11 , pp. 2893-2902
    • Dudgeon, C.1    Wang, P.2    Sun, X.3    Peng, R.4    Sun, Q.5    Yu, J.6    Zhang, L.7
  • 31
    • 33744942924 scopus 로고    scopus 로고
    • PUMA dissociates Bax and BCL-XL to induce apoptosis in colon cancer cells
    • Ming L, Wang P, Bank A, Yu J and Zhang L. PUMA dissociates Bax and BCL-XL to induce apoptosis in colon cancer cells. J Biol Chem. 2006; 281(23):16034-16042.
    • (2006) J Biol Chem , vol.281 , Issue.23 , pp. 16034-16042
    • Ming, L.1    Wang, P.2    Bank, A.3    Yu, J.4    Zhang, L.5
  • 32
    • 4143154293 scopus 로고    scopus 로고
    • Cooperative binding of tetrameric p53 to DNA
    • Weinberg RL, Veprintsev DB and Fersht AR. Cooperative binding of tetrameric p53 to DNA. J Mol Biol. 2004; 341(5):1145-1159.
    • (2004) J Mol Biol , vol.341 , Issue.5 , pp. 1145-1159
    • Weinberg, R.L.1    Veprintsev, D.B.2    Fersht, A.R.3
  • 33
    • 79952449224 scopus 로고    scopus 로고
    • Destabilization of Bcr-Abl/ Jak2 Network by a Jak2/Abl Kinase Inhibitor ON044580 Overcomes Drug Resistance in Blast Crisis Chronic Myelogenous Leukemia (CML)
    • Samanta AK, Chakraborty SN, Wang Y, Schlette E, Reddy EP and Arlinghaus RB. Destabilization of Bcr-Abl/ Jak2 Network by a Jak2/Abl Kinase Inhibitor ON044580 Overcomes Drug Resistance in Blast Crisis Chronic Myelogenous Leukemia (CML). Genes & cancer. 2010; 1(4):346-359.
    • (2010) Genes & cancer , vol.1 , Issue.4 , pp. 346-359
    • Samanta, A.K.1    Chakraborty, S.N.2    Wang, Y.3    Schlette, E.4    Reddy, E.P.5    Arlinghaus, R.B.6
  • 34
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response to p53
    • Vousden KH and Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer. 2002; 2(8):594-604.
    • (2002) Nat Rev Cancer , vol.2 , Issue.8 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 35
    • 34547935761 scopus 로고    scopus 로고
    • Living with p53, dying of p53
    • Aylon Y and Oren M. Living with p53, dying of p53. Cell. 2007; 130(4):597-600.
    • (2007) Cell , vol.130 , Issue.4 , pp. 597-600
    • Aylon, Y.1    Oren, M.2
  • 36
    • 34547956843 scopus 로고    scopus 로고
    • hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes
    • Tanaka T, Ohkubo S, Tatsuno I and Prives C. hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes. Cell. 2007; 130(4):638-650.
    • (2007) Cell , vol.130 , Issue.4 , pp. 638-650
    • Tanaka, T.1    Ohkubo, S.2    Tatsuno, I.3    Prives, C.4
  • 37
    • 34548049032 scopus 로고    scopus 로고
    • Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation
    • Das S, Raj L, Zhao B, Kimura Y, Bernstein A, Aaronson SA and Lee SW. Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation. Cell. 2007; 130(4):624-637.
    • (2007) Cell , vol.130 , Issue.4 , pp. 624-637
    • Das, S.1    Raj, L.2    Zhao, B.3    Kimura, Y.4    Bernstein, A.5    Aaronson, S.A.6    Lee, S.W.7
  • 38
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the Light: The Growing Complexity of p53
    • Vousden KH and Prives C. Blinded by the Light: The Growing Complexity of p53. Cell. 2009; 137(3):413-431.
    • (2009) Cell , vol.137 , Issue.3 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 39
    • 33846704798 scopus 로고    scopus 로고
    • p53 and p73 display common and distinct requirements for sequence specific binding to DNA
    • Lokshin M, Li Y, Gaiddon C and Prives C. p53 and p73 display common and distinct requirements for sequence specific binding to DNA. Nucleic Acids Res. 2007; 35(1): 340-352.
    • (2007) Nucleic Acids Res , vol.35 , Issue.1 , pp. 340-352
    • Lokshin, M.1    Li, Y.2    Gaiddon, C.3    Prives, C.4
  • 40
    • 0034650611 scopus 로고    scopus 로고
    • p73 competes with p53 and attenuates its response in a human ovarian cancer cell line
    • Vikhanskaya F, D'Incalci M and Broggini M. p73 competes with p53 and attenuates its response in a human ovarian cancer cell line. Nucleic Acids Res. 2000; 28(2):513-519.
    • (2000) Nucleic Acids Res , vol.28 , Issue.2 , pp. 513-519
    • Vikhanskaya, F.1    D'Incalci, M.2    Broggini, M.3
  • 41
    • 34047223196 scopus 로고    scopus 로고
    • Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
    • Li Y and Prives C. Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function? Oncogene. 2007; 26(15):2220-2225.
    • (2007) Oncogene , vol.26 , Issue.15 , pp. 2220-2225
    • Li, Y.1    Prives, C.2
  • 42
    • 0037134475 scopus 로고    scopus 로고
    • Transactivationdeficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: implications for tumorigenesis
    • Stiewe T, Theseling CC and Putzer BM. Transactivationdeficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: implications for tumorigenesis. J Biol Chem. 2002; 277(16):14177-14185.
    • (2002) J Biol Chem , vol.277 , Issue.16 , pp. 14177-14185
    • Stiewe, T.1    Theseling, C.C.2    Putzer, B.M.3
  • 44
    • 78049302116 scopus 로고    scopus 로고
    • p53 post-translational modification: deregulated in tumorigenesis
    • Dai C and Gu W. p53 post-translational modification: deregulated in tumorigenesis. Trends Mol Med. 2010; 16(11):528-536.
    • (2010) Trends Mol Med , vol.16 , Issue.11 , pp. 528-536
    • Dai, C.1    Gu, W.2
  • 45
    • 34547753615 scopus 로고    scopus 로고
    • p63 and p73 in human cancer: defining the network
    • Deyoung MP and Ellisen LW. p63 and p73 in human cancer: defining the network. Oncogene. 2007; 26(36):5169-5183.
    • (2007) Oncogene , vol.26 , Issue.36 , pp. 5169-5183
    • Deyoung, M.P.1    Ellisen, L.W.2
  • 46
    • 26644455289 scopus 로고    scopus 로고
    • Full-length p73alpha represses drug-induced apoptosis in small cell lung carcinoma cells
    • Nyman U, Sobczak-Pluta A, Vlachos P, Perlmann T, Zhivotovsky B and Joseph B. Full-length p73alpha represses drug-induced apoptosis in small cell lung carcinoma cells. J Biol Chem. 2005; 280(40):34159-34169.
    • (2005) J Biol Chem , vol.280 , Issue.40 , pp. 34159-34169
    • Nyman, U.1    Sobczak-Pluta, A.2    Vlachos, P.3    Perlmann, T.4    Zhivotovsky, B.5    Joseph, B.6
  • 47
    • 79953155314 scopus 로고    scopus 로고
    • TAp73 induction by nitric oxide: regulation by checkpoint kinase 1 (CHK1) and protection against apoptosis
    • Tebbi A, Guittet O, Cottet MH, Vesin MF and Lepoivre M. TAp73 induction by nitric oxide: regulation by checkpoint kinase 1 (CHK1) and protection against apoptosis. J Biol Chem. 2011; 286(10):7873-7884.
    • (2011) J Biol Chem , vol.286 , Issue.10 , pp. 7873-7884
    • Tebbi, A.1    Guittet, O.2    Cottet, M.H.3    Vesin, M.F.4    Lepoivre, M.5
  • 48
    • 51649088367 scopus 로고    scopus 로고
    • E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines
    • Kitagawa M, Aonuma M, Lee SH, Fukutake S and McCormick F. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines. Oncogene. 2008; 27(40): 5303-5314.
    • (2008) Oncogene , vol.27 , Issue.40 , pp. 5303-5314
    • Kitagawa, M.1    Aonuma, M.2    Lee, S.H.3    Fukutake, S.4    McCormick, F.5
  • 50
    • 18144382653 scopus 로고    scopus 로고
    • p73-induced apoptosis: a question of compartments and cooperation
    • Dobbelstein M, Strano S, Roth J and Blandino G. p73-induced apoptosis: a question of compartments and cooperation. Biochem Biophys Res Commun. 2005; 331(3): 688-693.
    • (2005) Biochem Biophys Res Commun , vol.331 , Issue.3 , pp. 688-693
    • Dobbelstein, M.1    Strano, S.2    Roth, J.3    Blandino, G.4
  • 52
    • 2442494895 scopus 로고    scopus 로고
    • The common and distinct target genes of the p53 family transcription factors
    • Harms K, Nozell S and Chen X. The common and distinct target genes of the p53 family transcription factors. Cell Mol Life Sci. 2004; 61(7-8):822-842.
    • (2004) Cell Mol Life Sci , vol.61 , Issue.7-8 , pp. 822-842
    • Harms, K.1    Nozell, S.2    Chen, X.3
  • 54
    • 20444453656 scopus 로고    scopus 로고
    • Relief of p53-mediated telomerase suppression by p73
    • Toh WH, Kyo S and Sabapathy K. Relief of p53-mediated telomerase suppression by p73. J Biol Chem. 2005; 280(17):17329-17338.
    • (2005) J Biol Chem , vol.280 , Issue.17 , pp. 17329-17338
    • Toh, W.H.1    Kyo, S.2    Sabapathy, K.3
  • 57
    • 0034576495 scopus 로고    scopus 로고
    • P63 and P73: P53 mimics, menaces and more
    • Yang A and McKeon F. P63 and P73: P53 mimics, menaces and more. Nat Rev Mol Cell Biol. 2000; 1(3):199-207.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , Issue.3 , pp. 199-207
    • Yang, A.1    McKeon, F.2
  • 59
    • 0033600234 scopus 로고    scopus 로고
    • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
    • Gong JG, Costanzo A, Yang HQ, Melino G, Kaelin WG Jr, Levrero M and Wang JY. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature. 1999; 399(6738):806-809.
    • (1999) Nature , vol.399 , Issue.6738 , pp. 806-809
    • Gong, J.G.1    Costanzo, A.2    Yang, H.Q.3    Melino, G.4    Kaelin Jr., W.G.5    Levrero, M.6    Wang, J.Y.7
  • 61
    • 35748958407 scopus 로고    scopus 로고
    • TAp73 is a downstream target of p53 in controlling the cellular defense against stress
    • Wang J, Liu YX, Hande MP, Wong AC, Jin YJ and Yin Y. TAp73 is a downstream target of p53 in controlling the cellular defense against stress. J Biol Chem. 2007; 282(40):29152-29162.
    • (2007) J Biol Chem , vol.282 , Issue.40 , pp. 29152-29162
    • Wang, J.1    Liu, Y.X.2    Hande, M.P.3    Wong, A.C.4    Jin, Y.J.5    Yin, Y.6
  • 62
    • 70350707752 scopus 로고    scopus 로고
    • The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting
    • Lunghi P, Costanzo A, Mazzera L, Rizzoli V, Levrero M and Bonati A. The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting. Clin Cancer Res. 2009; 15(21):6495-6502.
    • (2009) Clin Cancer Res , vol.15 , Issue.21 , pp. 6495-6502
    • Lunghi, P.1    Costanzo, A.2    Mazzera, L.3    Rizzoli, V.4    Levrero, M.5    Bonati, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.