-
1
-
-
0028108985
-
Database of p53 gene somatic mutations in human tumors and cell lines
-
M. Hollstein, K. Rice, M.S. Greenblatt, T. Soussi, R. Fuchs, and T. Sorlie Database of p53 gene somatic mutations in human tumors and cell lines Nucl. Acids Res. 22 1994 3551 3555
-
(1994)
Nucl. Acids Res.
, vol.22
, pp. 3551-3555
-
-
Hollstein, M.1
Rice, K.2
Greenblatt, M.S.3
Soussi, T.4
Fuchs5
Sorlie, T.R.6
-
2
-
-
0029919634
-
Somatic point mutaions in the p53 gene of human tumors and cell lines: Updated compilation
-
M. Hollenstein, B. Shomer, M.S. Greenblatt, T. Soussi, E. Hovig, R. Montesano, and C.C. Harris Somatic point mutaions in the p53 gene of human tumors and cell lines: updated compilation Nucl. Acids Res. 24 1996 141 146
-
(1996)
Nucl. Acids Res.
, vol.24
, pp. 141-146
-
-
Hollenstein, M.1
Shomer, B.2
Greenblatt, M.S.3
Soussi, T.4
Hovig, E.5
Montesano6
Harris, C.C.R.7
-
3
-
-
0028209857
-
Sequence-specific transcriptional activation is essential for growth suppression by p53
-
J.A. Pietenpol, T. Tokino, S. Thiagalingam, W.S. El-Diery, K.W. Kinzler, and B. Vogelstein Sequence-specific transcriptional activation is essential for growth suppression by p53 Proc. Natl Acad. Sci. USA 91 1994 1998 2002
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 1998-2002
-
-
Pietenpol, J.A.1
Tokino, T.2
Thiagalingam, S.3
El-Diery, W.S.4
Kinzler5
Vogelstein, B.K.W.6
-
4
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
A.J. Levine p53, the cellular gatekeeper for growth and division Cell 88 1997 323 331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
5
-
-
0036674617
-
Live or let die: The cell's response to p53
-
K.H. Vousden, and X. Lu Live or let die: the cell's response to p53 Nature Rev. Cancer 2 2002 594 604
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden1
Lu, X.K.H.2
-
6
-
-
0025024469
-
Presence of a potent transcription activating sequence in the p53 protein
-
S. Fields, and S.K. Jang Presence of a potent transcription activating sequence in the p53 protein Science 249 1990 1046 1049
-
(1990)
Science
, vol.249
, pp. 1046-1049
-
-
Fields1
Jang, S.K.S.2
-
7
-
-
0026849821
-
Definition of a consensus binding site for p53
-
W.S. El-Deiry, S.E. Kern, J.A. Pietenpol, K.W. Kinzler, and B. Vogelstein Definition of a consensus binding site for p53 Nature Genet. 1 1992 45 49
-
(1992)
Nature Genet.
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler4
Vogelstein, B.K.W.5
-
8
-
-
0026650531
-
A transcriptionally active DNA-binding site for human p53 protein complexes
-
W.D. Funk, D.T. Pak, R.H. Karas, W.E. Wright, and J.W. Shay A transcriptionally active DNA-binding site for human p53 protein complexes Mol. Cell. Biol. 12 1992 2866 2871
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2866-2871
-
-
Funk, W.D.1
Pak, D.T.2
Karas, R.H.3
Wright4
Shay, J.W.W.E.5
-
9
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
-
Y. Cho, S. Gorina, P.D. Jeffrey, and N.P. Pavletich Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations Science 265 1994 346 355
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey3
Pavletich, N.P.P.D.4
-
10
-
-
0028943706
-
Interaction of p53 with Its consensus DNA-binding site
-
Y. Wang, J.F. Schwedes, D. Parks, K. Mann, and P. Tegtmeyer Interaction of p53 with Its consensus DNA-binding site Mol. Cell. Biol. 15 1995 2157 2165
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2157-2165
-
-
Wang, Y.1
Schwedes, J.F.2
Parks, D.3
Mann4
Tegtmeyer, P.K.5
-
11
-
-
0029021164
-
Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA
-
P. Balagurumoorthy, H. Sakamoto, M.S. Lewis, N. Zambrano, G.M. Clore, and A.M. Gronenborn Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA Proc. Natl Acad. Sci. USA 92 1995 8591 8595
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 8591-8595
-
-
Balagurumoorthy, P.1
Sakamoto, H.2
Lewis, M.S.3
Zambrano, N.4
Clore5
Gronenborn, A.M.G.M.6
-
12
-
-
0032526426
-
How p53 binds DNA as a tetramer
-
K.G. McLure, and P.W. Lee How p53 binds DNA as a tetramer EMBO J. 17 1998 3342 3350
-
(1998)
EMBO J.
, vol.17
, pp. 3342-3350
-
-
McLure1
Lee, P.W.K.G.2
-
13
-
-
0037066755
-
Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerzation of dimers
-
C.D. Nicholls, K.G. McLure, M.A. Shields, and P.W.K. Lee Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerzation of dimers J. Biol. Chem. 277 2002 12937 12945
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12937-12945
-
-
Nicholls, C.D.1
McLure, K.G.2
Shields3
Lee, P.W.K.M.A.4
-
14
-
-
0033081465
-
P53 DNA binding can be modulated by factors that alter the conformational equilibrium
-
K.G. McLure, and P.W. Lee p53 DNA binding can be modulated by factors that alter the conformational equilibrium EMBO J. 18 1999 763 770
-
(1999)
EMBO J.
, vol.18
, pp. 763-770
-
-
McLure1
Lee, P.W.K.G.2
-
15
-
-
0028124665
-
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR
-
G.M. Clore, J.G. Omichinski, K. Sakaguchi, N. Zambrano, H. Sakamoto, E. Appella, and A.M. Gronenborn High-resolution structure of the oligomerization domain of p53 by multidimensional NMR Science 265 1994 386 391
-
(1994)
Science
, vol.265
, pp. 386-391
-
-
Clore, G.M.1
Omichinski, J.G.2
Sakaguchi, K.3
Zambrano, N.4
Sakamoto, H.5
Appella6
Gronenborn, A.M.E.7
-
16
-
-
0028965832
-
Refined solution structure of the oligomerization domain of the tumour suppressor p53
-
G.M. Clore, J. Ernst, R. Clubb, J.G. Omichinski, W.M. Kennedy, and K. Sakaguchi Refined solution structure of the oligomerization domain of the tumour suppressor p53 Nature Struct. Biol. 2 1995 321 333
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 321-333
-
-
Clore, G.M.1
Ernst, J.2
Clubb, R.3
Omichinski, J.G.4
Kennedy5
Sakaguchi, K.W.M.6
-
17
-
-
0028952841
-
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
-
P.D. Jeffrey, S. Gorina, and N.P. Pavletich Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms Science 267 1995 1498 1502
-
(1995)
Science
, vol.267
, pp. 1498-1502
-
-
Jeffrey, P.D.1
Gorina2
Pavletich, N.P.S.3
-
18
-
-
0030722137
-
Hydrophobic side-chain size is a determinant of the three-dimensional structre of the p53 oligomerization domain
-
M. McCoy, E.S. Stavridi, J.L.F. Waterman, A.M. Wieczorek, S.J. Opella, and T.D. Halazonetis Hydrophobic side-chain size is a determinant of the three-dimensional structre of the p53 oligomerization domain EMBO J. 16 1997 6230 6236
-
(1997)
EMBO J.
, vol.16
, pp. 6230-6236
-
-
McCoy, M.1
Stavridi, E.S.2
Waterman, J.L.F.3
Wieczorek, A.M.4
Opella5
Halazonetis, T.D.S.J.6
-
19
-
-
0029000171
-
Thermodynamic analysis of the structural stability of the tetrameric oligomerization domain of p53 tumor suppressor
-
C.R. Johnson, P.E. Morin, C.H. Arrowsmith, and E. Freire Thermodynamic analysis of the structural stability of the tetrameric oligomerization domain of p53 tumor suppressor Biochemistry 34 1995 5309 5316
-
(1995)
Biochemistry
, vol.34
, pp. 5309-5316
-
-
Johnson, C.R.1
Morin, P.E.2
Arrowsmith3
Freire, E.C.H.4
-
20
-
-
0032525133
-
Nine hydrophobic side chains are key determinants of the thermodynamic stability and oligomerization status of tumour suppressor p53 tetramerization domain
-
M.G. Mateu, and A.R. Fersht Nine hydrophobic side chains are key determinants of the thermodynamic stability and oligomerization status of tumour suppressor p53 tetramerization domain EMBO J. 17 1998 2748 2758
-
(1998)
EMBO J.
, vol.17
, pp. 2748-2758
-
-
Mateu1
Fersht, A.R.M.G.2
-
21
-
-
0032906377
-
Mechanism of folding and assembly of a small tetrameric protein domain from tumor suppressor p53
-
M.G. Mateu, M.M. Sanchez Del Pino, and A.R. Fersht Mechanism of folding and assembly of a small tetrameric protein domain from tumor suppressor p53 Nature Struct. Biol. 6 1999 191 198
-
(1999)
Nature Struct. Biol.
, vol.6
, pp. 191-198
-
-
Mateu, M.G.1
Del Pino, S.2
Fersht, A.R.M.M.3
-
22
-
-
0028145057
-
P53 tagged sites from human genomic DNA
-
T. Tokino, G. Thiagalingam, W.S. El-Diery, T. Waldman, K.W. Kinzler, and B. Vogelstein p53 tagged sites from human genomic DNA Hum. Mol. Genet. 3 1994 1537 1542
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1537-1542
-
-
Tokino, T.1
Thiagalingam, G.2
El-Diery, W.S.3
Waldman, T.4
Kinzler5
Vogelstein, B.K.W.6
-
23
-
-
0030915267
-
Architectural accommodation in the complex of four p53 DNA binding domain peptides with th p21/waf1/cip1 DNA response element
-
A.K. Nagaich, V.B. Zhurkin, H. Sakamoto, A.A. Gorin, G.M. Clore, and A.M. Gronenborn Architectural accommodation in the complex of four p53 DNA binding domain peptides with th p21/waf1/cip1 DNA response element J. Biol. Chem. 272 1997 14830 14841
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14830-14841
-
-
Nagaich, A.K.1
Zhurkin, V.B.2
Sakamoto, H.3
Gorin, A.A.4
Clore5
Gronenborn, A.M.G.M.6
-
24
-
-
0033515035
-
P53-induced DNA bending and twisting: P53 tetramer binds on the outer side of a DNA loop and increases DNA twisting
-
A.K. Nagaich, V.B. Zhurkin, S.R. Durell, R.L. Jernigan, E. Appella, and R.E. Harrington p53-induced DNA bending and twisting: p53 tetramer binds on the outer side of a DNA loop and increases DNA twisting Proc. Natl Acad. Sci. USA 96 1999 1875 1880
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 1875-1880
-
-
Nagaich, A.K.1
Zhurkin, V.B.2
Durell, S.R.3
Jernigan, R.L.4
Appella5
Harrington, R.E.E.6
-
25
-
-
0030951978
-
DNA bending is essential for the site-specific recognition of DNA response elements by the DNA binding domain of the tumor suppressor protein p53
-
A.K. Nagaich, E. Appella, and R.E. Harrington DNA bending is essential for the site-specific recognition of DNA response elements by the DNA binding domain of the tumor suppressor protein p53 J. Biol. Chem. 272 1997 14842 14849
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14842-14849
-
-
Nagaich, A.K.1
Appella2
Harrington, R.E.E.3
-
26
-
-
0035895422
-
Conformation and rigidity of DNA microcircles containing waf1 response element for p53 regulatory protein
-
H. Zhou, Y. Zhang, Z. Ou-Yang, S.M. Lindsay, X.-Z. Feng, P. Balagurumoorthy, and R.E. Harrington Conformation and rigidity of DNA microcircles containing waf1 response element for p53 regulatory protein J. Mol. Biol. 306 2001 227 238
-
(2001)
J. Mol. Biol.
, vol.306
, pp. 227-238
-
-
Zhou, H.1
Zhang, Y.2
Ou-Yang, Z.3
Lindsay, S.M.4
Feng, X.-Z.5
Balagurumoorthy6
Harrington, R.E.P.7
-
27
-
-
0035966083
-
NMR spectroscopy reveals the solution dimerzation interface of p53 core domains bound to their consensus DNA
-
C. Klein, E. Planker, T. Diercks, H. Kessler, K.-P. Kunkele, and K. Lang NMR spectroscopy reveals the solution dimerzation interface of p53 core domains bound to their consensus DNA J. Biol. Chem. 276 2001 49020 49027
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 49020-49027
-
-
Klein, C.1
Planker, E.2
Diercks, T.3
Kessler, H.4
Kunkele5
Lang, K.K.-P.6
-
28
-
-
0036301402
-
Recognition of DNA by p53 core domain and location of intermolecular contacts of cooperative binding
-
T.M. Rippin, S.M.V. Freund, D.B. Veprintsev, and A.R. Fersht Recognition of DNA by p53 core domain and location of intermolecular contacts of cooperative binding J. Mol. Biol. 319 2002 351 358
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 351-358
-
-
Rippin, T.M.1
Freund, S.M.V.2
Veprintsev3
Fersht, A.R.D.B.4
-
29
-
-
84970061891
-
Solution structure of the tetrameric minimum transforming domain of p53
-
W. Lee, T.S. Harvey, Y. Yin, P. Yau, D. Litchfield, and C.H. Arrowshmith Solution structure of the tetrameric minimum transforming domain of p53 Nature Struct. Biol. 1 1994 877 890
-
(1994)
Nature Struct. Biol.
, vol.1
, pp. 877-890
-
-
Lee, W.1
Harvey, T.S.2
Yin, Y.3
Yau, P.4
Litchfield5
Arrowshmith, C.H.D.6
-
30
-
-
0017146579
-
Ion effects on ligand-nucleic acid interactions
-
M.T. Record, T.M. Lohman, and P.L. de Haseth Ion effects on ligand-nucleic acid interactions J. Mol. Biol. 107 1976 145 158
-
(1976)
J. Mol. Biol.
, vol.107
, pp. 145-158
-
-
Record, M.T.1
Lohman2
De Haseth, P.L.T.M.3
-
31
-
-
0026323912
-
Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNA
-
M.T. Record Jr, J.-H. Ha, and M.A. Fisher Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNA Methods Enzymol. 208 1991 291 343
-
(1991)
Methods Enzymol.
, vol.208
, pp. 291-343
-
-
Record Jr., M.T.1
Ha, J.-H.2
Fisher, M.A.3
-
33
-
-
0031592940
-
Affinity and specificity of trp repressor-DNA interactions studied with fluorescent oligonucleotides
-
R.J. Reedstrom, M.P. Brown, A. Grillo, D. Roen, and C.A. Royer Affinity and specificity of trp repressor-DNA interactions studied with fluorescent oligonucleotides J. Mol. Biol. 273 1997 572 585
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 572-585
-
-
Reedstrom, R.J.1
Brown, M.P.2
Grillo, A.3
Roen4
Royer, C.A.D.5
-
34
-
-
0027214299
-
Fluorescence anisotropy assays implicate protein-protein interactions in regulating trp repressor DNA binding
-
V. LeTilly, and C.A. Royer Fluorescence anisotropy assays implicate protein-protein interactions in regulating trp repressor DNA binding Biochemistry 32 1993 7753 7758
-
(1993)
Biochemistry
, vol.32
, pp. 7753-7758
-
-
Letilly1
Royer, C.A.V.2
-
35
-
-
0030598345
-
Characterization of charge change super-repressor mutants of trp repressor: Effects on oligomerization conformation, ligation and stability
-
R.J. Reedstrom, K.S. Martin, S. Vangala, S. Mahoney, E.W. Wilker, and C.A. Royer Characterization of charge change super-repressor mutants of trp repressor: effects on oligomerization conformation, ligation and stability J. Mol. Biol. 264 1996 32 45
-
(1996)
J. Mol. Biol.
, vol.264
, pp. 32-45
-
-
Reedstrom, R.J.1
Martin, K.S.2
Vangala, S.3
Mahoney, S.4
Wilker5
Royer, C.A.E.W.6
-
36
-
-
0035830451
-
Kinetic studies of Fos-Jun-DNA complex formation: DNA binding prior to dimerization
-
J.J. Kohler, and A. Schepartz Kinetic studies of Fos-Jun-DNA complex formation: DNA binding prior to dimerization Biochemistry 40 2001 130 142
-
(2001)
Biochemistry
, vol.40
, pp. 130-142
-
-
Kohler1
Schepartz, A.J.J.2
-
38
-
-
0032580207
-
Allosteric effects of DNA on transcriptional regulators
-
J.A. Lefstin, and K.R. Yamamoto Allosteric effects of DNA on transcriptional regulators Nature 392 1998 885 888
-
(1998)
Nature
, vol.392
, pp. 885-888
-
-
Lefstin1
Yamamoto, K.R.J.A.2
-
39
-
-
0032853774
-
Mutant p53: Gain-of-function oncoproteins and wild-type p53 inactivators
-
K. Roemer Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators Biol. Chem. 380 1999 879 887
-
(1999)
Biol. Chem.
, vol.380
, pp. 879-887
-
-
Roemer, K.1
-
40
-
-
0033552638
-
Twenty years of p53 research: Structural and functional aspects of the p53 protein
-
P. May, and E. May Twenty years of p53 research: structural and functional aspects of the p53 protein Oncogene 18 1999 7621 7636
-
(1999)
Oncogene
, vol.18
, pp. 7621-7636
-
-
May1
May, E.P.2
-
41
-
-
0026569616
-
Analysis of p53 expression in human tumors-an antibody raised against human P53 expressed in Escherichia-Coli
-
C.A. Midgley, C.J. Fisher, J. Bartek, B. Vojtesek, D. Lane, and D.M. Barnes Analysis of p53 expression in human tumors-an antibody raised against human P53 expressed in Escherichia-Coli J. Cell Sci. 101 1992 183
-
(1992)
J. Cell Sci.
, vol.101
, pp. 183
-
-
Midgley, C.A.1
Fisher, C.J.2
Bartek, J.3
Vojtesek, B.4
Lane5
Barnes, D.M.D.6
-
42
-
-
0030593468
-
Over-production of proteins in Escherichia coli: Mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels
-
B. Miroux, and J.E. Walker Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels J. Mol. Biol. 260 1996 289 298
-
(1996)
J. Mol. Biol.
, vol.260
, pp. 289-298
-
-
Miroux1
Walker, J.E.B.2
-
43
-
-
0000221670
-
Chromatography of nucleic acids
-
F.M. Ausubel R. Brent R.E. Kingston D.D. Moore J.G. Seidman J.A. Smith K. Struhl Wiley New York
-
E.J. Richards Chromatography of nucleic acids F.M. Ausubel R. Brent R.E. Kingston D.D. Moore J.G. Seidman J.A. Smith K. Struhl Current Protocols in Molecular Biology 1997 Wiley New York 2.13.1 2.13.3
-
(1997)
Current Protocols in Molecular Biology
, pp. 2131-2133
-
-
Richards, E.J.1
-
44
-
-
0004136246
-
Preparation of single-stranded and double-stranded DNAs by hydroxyapatite chromatography
-
Cold Spring Harbor Laboratory Press, New York.
-
Sambrook, J. & Russell, D.W. (2001). Preparation of single-stranded and double-stranded DNAs by hydroxyapatite chromatography. In Molecular Cloning: A Laboratory Manual, 3rd edit., vol. 3, pp. A8.32-A8.34, Cold Spring Harbor Laboratory Press, New York.
-
(2001)
Molecular Cloning: A Laboratory Manual, 3rd Edit.
, vol.3
-
-
Sambrook, J.1
Russell, D.W.2
-
45
-
-
0024448151
-
Calculation of protein extinction coefficients from amino acid sequence data [published erratum appears in Anal Biochem Sep;189(2):283]
-
S.C. Gill, and P.H. von Hippel Calculation of protein extinction coefficients from amino acid sequence data [published erratum appears in Anal Biochem Sep;189(2):283] Anal. Biochem. 182 1990 319 326
-
(1990)
Anal. Biochem.
, vol.182
, pp. 319-326
-
-
Gill1
Von Hippel, P.H.S.C.2
|