The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 10, 2007, Pages 4054-4059

  Wang, Peng ^a   Yu, Jian ^a   Zhang, Lin ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Caspases; Mitochondria; p53 binding sites; Promoter; Transcription

Indexed keywords

BH3 PROTEIN; GENE PRODUCT; PROTEIN BCL 2; PROTEIN P53; PROTEIN PUMA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BBC3 PROTEIN, HUMAN; HISTONE; ONCOPROTEIN;

APOPTOSIS; ARTICLE; BINDING SITE; CANCER CELL; CANCER INHIBITION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; GENE; GENE ACTIVATION; GENE EXPRESSION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FAMILY; PROTEIN INDUCTION; PROTEIN TARGETING; PUMA GENE; TRANSCRIPTION INITIATION; BIOLOGICAL MODEL; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING; TUMOR CELL LINE;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; DNA DAMAGE; HISTONES; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34247211554     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0700020104     Document Type: Article

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