-
1
-
-
0034079520
-
The p53/p63/p73 family of transcription factors: Overlapping and distinct functions
-
Levrero,M., De Laurenzi,V., Costanzo,A., Gong,J., Wang,J.Y. and Melino,G. (2000) The p53/p63/p73 family of transcription factors: overlapping and distinct functions. J. Cell Sci., 113, 1661-1670.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 1661-1670
-
-
Levrero, M.1
De Laurenzi, V.2
Costanzo, A.3
Gong, J.4
Wang, J.Y.5
Melino, G.6
-
2
-
-
0035966345
-
p53, p63 and p73 - Solos, alliances and feuds among family members
-
Moll,U.M., Erster,S. and Zaika,A. (2001) p53, p63 and p73 - solos, alliances and feuds among family members. Biochim. Biophys. Acta., 1552, 47-59.
-
(2001)
Biochim. Biophys. Acta.
, vol.1552
, pp. 47-59
-
-
Moll, U.M.1
Erster, S.2
Zaika, A.3
-
3
-
-
0036468523
-
On the shoulders of giants: P63, p73 and the rise of p53
-
Yang,A., Kaghad,M., Caput,D. and McKeon,F. (2002) On the shoulders of giants: P63, p73 and the rise of p53. Trends Genet., 18, 90-95.
-
(2002)
Trends Genet.
, vol.18
, pp. 90-95
-
-
Yang, A.1
Kaghad, M.2
Caput, D.3
McKeon, F.4
-
4
-
-
0035913975
-
Caenorhabditis elegans p53: Role in apoptosis, meiosis, and stress resistance
-
Derry,W.B., Putzke,A.P. and Rothman,J.H. (2001) Caenorhabditis elegans p53: Role in apoptosis, meiosis, and stress resistance. Science, 294, 591-595.
-
(2001)
Science
, vol.294
, pp. 591-595
-
-
Derry, W.B.1
Putzke, A.P.2
Rothman, J.H.3
-
5
-
-
0035975986
-
The C.elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis
-
Schumacher,B., Hofmann,K., Boulton,S. and Gartner,A. (2001) The C.elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis. Curr. Biol., 11, 1722-1727.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1722-1727
-
-
Schumacher, B.1
Hofmann, K.2
Boulton, S.3
Gartner, A.4
-
6
-
-
0038705141
-
Ehp53, an Entamoeba histolytica protein, ancestor of the mammalian tumour suppressor p53
-
Mendoza,L., Orozco,E., Rodriguez,M.A., Garcia-Rivera,G., Sanchez,T., Garcia,E. and Gariglio,P. (2003) Ehp53, an Entamoeba histolytica protein, ancestor of the mammalian tumour suppressor p53. Microbiology, 149, 885-893.
-
(2003)
Microbiology
, vol.149
, pp. 885-893
-
-
Mendoza, L.1
Orozco, E.2
Rodriguez, M.A.3
Garcia-Rivera, G.4
Sanchez, T.5
Garcia, E.6
Gariglio, P.7
-
7
-
-
33646798450
-
p53/p63/p73 isoforms: An orchestra of isoforms to harmonise cell differentiation and response to stress
-
Murray-Zmijewski,F., Lane,D.P. and Bourdon,J.C. (2006) p53/p63/p73 isoforms: An orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ., 13, 962-972.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 962-972
-
-
Murray-Zmijewski, F.1
Lane, D.P.2
Bourdon, J.C.3
-
8
-
-
33646423278
-
Structural basis for gene activation by p53 family members
-
Scoumanne,A., Harms,K.L. and Chen,X. (2005) Structural basis for gene activation by p53 family members. Cancer Biol. Ther., 4, 1178-1185.
-
(2005)
Cancer Biol. Ther.
, vol.4
, pp. 1178-1185
-
-
Scoumanne, A.1
Harms, K.L.2
Chen, X.3
-
9
-
-
33646807491
-
Transcriptional regulation by p53: One protein, many possibilities
-
Laptenko,O. and Prives,C. (2006) Transcriptional regulation by p53: One protein, many possibilities. Cell Death Differ., 13, 951-961.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 951-961
-
-
Laptenko, O.1
Prives, C.2
-
10
-
-
0026849821
-
Definition of a consensus binding site for p53
-
el-Deiry,W.S., Kern,S.E., Pietenpol,J.A., Kinzler,K.W. and Vogelstein,B. (1992) Definition of a consensus binding site for p53. Nature Genet., 1, 45-49.
-
(1992)
Nature Genet.
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
11
-
-
0027521114
-
Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants
-
Halazonetis,T.D. and Kandil,A.N. (1993) Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. EMBO J., 12, 5057-5064.
-
(1993)
EMBO J.
, vol.12
, pp. 5057-5064
-
-
Halazonetis, T.D.1
Kandil, A.N.2
-
12
-
-
0032931517
-
The p53 pathway
-
Prives,C. and Hall,P.A. (1999) The p53 pathway. J. Pathol., 187, 112-126.
-
(1999)
J. Pathol.
, vol.187
, pp. 112-126
-
-
Prives, C.1
Hall, P.A.2
-
13
-
-
0032526426
-
How p53 binds DNA as a tetramer
-
McLure,K.G. and Lee,P.W. (1998) How p53 binds DNA as a tetramer. EMBO J., 17, 3342-3350.
-
(1998)
EMBO J.
, vol.17
, pp. 3342-3350
-
-
McLure, K.G.1
Lee, P.W.2
-
14
-
-
0027522365
-
The p53 protein is an unusually shaped tetramer that binds directly to DNA
-
Friedman,P.N., Chen,X., Bargonetti,J. and Prives,C. (1993) The p53 protein is an unusually shaped tetramer that binds directly to DNA. Proc. Natl Acad. Sci. USA, 90, 3319-3323.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 3319-3323
-
-
Friedman, P.N.1
Chen, X.2
Bargonetti, J.3
Prives, C.4
-
15
-
-
33745209412
-
Structural basis of DNA recognition by p53 tetramers
-
Kitayner,M., Rozenberg,H., Kessler,N., Rabinovich,D., Shaulov,L., Haran,T.E. and Shakked,Z. (2006) Structural basis of DNA recognition by p53 tetramers. Mol. Cell, 22, 741-753.
-
(2006)
Mol. Cell
, vol.22
, pp. 741-753
-
-
Kitayner, M.1
Rozenberg, H.2
Kessler, N.3
Rabinovich, D.4
Shaulov, L.5
Haran, T.E.6
Shakked, Z.7
-
16
-
-
33746002633
-
Structure of the p53 Core Domain Dimer Bound to DNA
-
Ho,W.C., Fitzgerald,M.X. and Marmorstein,R. (2006) Structure of the p53 Core Domain Dimer Bound to DNA. J. Biol. Chem., 281, 20494-20502.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 20494-20502
-
-
Ho, W.C.1
Fitzgerald, M.X.2
Marmorstein, R.3
-
17
-
-
0030768181
-
DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53
-
Kim,E., Albrechtsen,N. and Deppert,W. (1997) DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53. Oncogene, 15, 857-869.
-
(1997)
Oncogene
, vol.15
, pp. 857-869
-
-
Kim, E.1
Albrechtsen, N.2
Deppert, W.3
-
18
-
-
0035028599
-
Kinetics of p53 binding to promoter sites in vivo
-
Szak,S.T., Mays,D. and Pietenpol,J.A. (2001) Kinetics of p53 binding to promoter sites in vivo. Mol. Cell. Biol., 21, 3375-3386.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3375-3386
-
-
Szak, S.T.1
Mays, D.2
Pietenpol, J.A.3
-
19
-
-
0037039319
-
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
-
Kaeser,M.D. and Iggo,R.D. (2002) Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo. Proc. Natl Acad. Sci. USA, 99, 95-100.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 95-100
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
20
-
-
0033584842
-
One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element
-
Thornborrow,E.C. and Manfredi,J.J. (1999) One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element. J. Biol. Chem., 274, 33747-33756.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33747-33756
-
-
Thornborrow, E.C.1
Manfredi, J.J.2
-
21
-
-
0037038699
-
Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding site
-
Qian,H., Wang,T., Naumovski,L., Lopez,C.D. and Brachmann,R.K. (2002) Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding site. Oncogene, 21, 7901-7911.
-
(2002)
Oncogene
, vol.21
, pp. 7901-7911
-
-
Qian, H.1
Wang, T.2
Naumovski, L.3
Lopez, C.D.4
Brachmann, R.K.5
-
22
-
-
0036892060
-
Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence
-
Inga,A., Storici,F., Darden,T.A. and Resnick,M.A. (2002) Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. Mol. Cell. Biol., 22, 8612-8625.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8612-8625
-
-
Inga, A.1
Storici, F.2
Darden, T.A.3
Resnick, M.A.4
-
23
-
-
0037173059
-
The p53MH algorithm and its application in detecting p53-responsive genes
-
Hoh,J., Jin,S., Parrado,T., Edington,J., Levine,A.J. and Ott,J. (2002) The p53MH algorithm and its application in detecting p53-responsive genes. Proc. Natl Acad. Sci. USA, 99, 8467-8472.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 8467-8472
-
-
Hoh, J.1
Jin, S.2
Parrado, T.3
Edington, J.4
Levine, A.J.5
Ott, J.6
-
24
-
-
30344478870
-
A global map of p53 transcription-factor binding sites in the human genome
-
Wei,C.L., Wu,Q., Vega,V.B., Chiu,K.P., Ng,P., Zhang,T., Shahab,A., Yong,H.C., Fu,Y., Weng,Z. et al. (2006) A global map of p53 transcription-factor binding sites in the human genome. Cell, 124, 207-219.
-
(2006)
Cell
, vol.124
, pp. 207-219
-
-
Wei, C.L.1
Wu, Q.2
Vega, V.B.3
Chiu, K.P.4
Ng, P.5
Zhang, T.6
Shahab, A.7
Yong, H.C.8
Fu, Y.9
Weng, Z.10
-
25
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users
-
Olivier,M., Eeles,R., Hollstein,M., Khan,M.A., Harris,C.C. and Hainaut,P. (2002) The IARC TP53 database: New online mutation analysis and recommendations to users. Hum. Mutat., 19, 607-614.
-
(2002)
Hum. Mutat.
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
26
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
-
Cho,Y., Gorina,S., Jeffrey,P.D. and Pavletich,N.P. (1994) Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations. Science, 265, 346-355.
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
27
-
-
0027771333
-
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots
-
Pavletich,N.P., Chambers,K.A. and Pabo,C.O. (1993) The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots. Genes Dev., 7, 2556-2564.
-
(1993)
Genes Dev.
, vol.7
, pp. 2556-2564
-
-
Pavletich, N.P.1
Chambers, K.A.2
Pabo, C.O.3
-
28
-
-
0027269545
-
A structural role for metal ions in the 'wild-type' conformation of the tumor suppressor protein p53
-
Hainaut,P. and Milner,J. (1993) A structural role for metal ions in the 'wild-type' conformation of the tumor suppressor protein p53. Cancer Res., 53, 1739-1742.
-
(1993)
Cancer Res.
, vol.53
, pp. 1739-1742
-
-
Hainaut, P.1
Milner, J.2
-
29
-
-
0031978026
-
Modulation of p53 protein conformation and DNA-binding activity by intracellular chelation of zinc
-
Verhaegh,G.W., Parat,M.O., Richard,M.J. and Hainaut,P. (1998) Modulation of p53 protein conformation and DNA-binding activity by intracellular chelation of zinc. Mol. Carcinog., 21, 205-214.
-
(1998)
Mol. Carcinog.
, vol.21
, pp. 205-214
-
-
Verhaegh, G.W.1
Parat, M.O.2
Richard, M.J.3
Hainaut, P.4
-
30
-
-
0034597536
-
Metalloregulation of the tumor suppressor protein p53: Zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells
-
Meplan,C., Richard,M.J. and Hainaut,P. (2000) Metalloregulation of the tumor suppressor protein p53: Zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells. Oncogene, 19, 5227-5236.
-
(2000)
Oncogene
, vol.19
, pp. 5227-5236
-
-
Meplan, C.1
Richard, M.J.2
Hainaut, P.3
-
31
-
-
8644241631
-
p53 linear diffusion along DNA requires its C terminus
-
McKinney,K., Mattia,M., Gottifredi,V. and Prives,C. (2004) p53 linear diffusion along DNA requires its C terminus. Mol. Cell, 16, 413-424.
-
(2004)
Mol. Cell
, vol.16
, pp. 413-424
-
-
McKinney, K.1
Mattia, M.2
Gottifredi, V.3
Prives, C.4
-
32
-
-
0034881964
-
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment
-
Espinosa,J.M. and Emerson,B.M. (2001) Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment. Mol. Cell, 8, 57-69.
-
(2001)
Mol. Cell
, vol.8
, pp. 57-69
-
-
Espinosa, J.M.1
Emerson, B.M.2
-
33
-
-
0034862475
-
The C-terminus of p53: The more you learn the less you know
-
Ahn,J. and Prives,C. (2001) The C-terminus of p53: The more you learn the less you know. Nature Struct. Biol., 8, 730-732.
-
(2001)
Nature Struct. Biol.
, vol.8
, pp. 730-732
-
-
Ahn, J.1
Prives, C.2
-
34
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
Kaghad,M., Bonnet,H., Yang,A., Creancier,L., Biscan,J.C., Valent,A., Minty,A., Chalon,P., Lelias,J.M., Dumont,X. et al. (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell, 90, 809-819.
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
-
35
-
-
0031564954
-
p73 is a simian [correction of human] p53-related protein that can induce apoptosis
-
Jost,C.A., Marin,M.C. and Kaelin,W.G.,Jr (1997) p73 is a simian [correction of human] p53-related protein that can induce apoptosis. Nature, 389, 191-194.
-
(1997)
Nature
, vol.389
, pp. 191-194
-
-
Jost, C.A.1
Marin, M.C.2
Kaelin Jr., W.G.3
-
36
-
-
0034927749
-
p53 family update: P73 and p63 develop their own identities
-
Irwin,M.S. and Kaelin,W.G. (2001) p53 family update: P73 and p63 develop their own identities. Cell Growth Differ., 12, 337-349.
-
(2001)
Cell Growth Differ.
, vol.12
, pp. 337-349
-
-
Irwin, M.S.1
Kaelin, W.G.2
-
37
-
-
29644436953
-
P73, a sophisticated p53 family member in the cancer world
-
Ozaki,T. and Nakagawara,A. (2005) p73, a sophisticated p53 family member in the cancer world. Cancer Sci., 96, 729-737.
-
(2005)
Cancer Sci.
, vol.96
, pp. 729-737
-
-
Ozaki, T.1
Nakagawara, A.2
-
38
-
-
18144426821
-
Regulation of the p73 protein stability and degradation
-
Oberst,A., Rossi,W., Salomoni,P., Pandolfi,P.P., Oren,M., Melino,G. and Bernassola,F. (2005) Regulation of the p73 protein stability and degradation. Biochem. Biophys. Res. Commun., 331, 707-712.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.331
, pp. 707-712
-
-
Oberst, A.1
Rossi, W.2
Salomoni, P.3
Pandolfi, P.P.4
Oren, M.5
Melino, G.6
Bernassola, F.7
-
39
-
-
3543110350
-
P63 and p73: Roles in development and tumor formation
-
Moll,U.M. and Slade,N. (2004) p63 and p73: Roles in development and tumor formation. Mol. Cancer Res., 2, 371-386.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 371-386
-
-
Moll, U.M.1
Slade, N.2
-
40
-
-
0345059168
-
Functional regulation of p73 and p63: Development and cancer
-
Melino,G., Lu,X., Gasco,M., Crook,T. and Knight,R.A. (2003) Functional regulation of p73 and p63: Development and cancer. Trends Biochem. Sci., 28, 663-670.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 663-670
-
-
Melino, G.1
Lu, X.2
Gasco, M.3
Crook, T.4
Knight, R.A.5
-
41
-
-
0037134475
-
Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: Implications for tumorigenesis
-
Stiewe,T., Theseling,C.C. and Putzer,B.M. (2002) Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: Implications for tumorigenesis. J. Biol. Chem., 277, 14177-14185.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14177-14185
-
-
Stiewe, T.1
Theseling, C.C.2
Putzer, B.M.3
-
42
-
-
0036203514
-
Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter
-
Nakagawa,T., Takahashi,M., Ozaki,T., Watanabe Ki,K., Todo,S., Mizuguchi,H., Hayakawa,T. and Nakagawara,A. (2002) Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter. Mol. Cell. Biol., 22, 2575-2585.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2575-2585
-
-
Nakagawa, T.1
Takahashi, M.2
Ozaki, T.3
Watanabe Ki, K.4
Todo, S.5
Mizuguchi, H.6
Hayakawa, T.7
Nakagawara, A.8
-
43
-
-
18244402691
-
Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53
-
Grob,T.J., Novak,U., Maisse,C., Barcaroli,D., Luthi,A.U., Pirnia,F., Hugli,B., Graber,H.U., De Laurenzi,V., Fey,M.F. et al. (2001) Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53. Cell Death Differ., 8, 1213-1223.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 1213-1223
-
-
Grob, T.J.1
Novak, U.2
Maisse, C.3
Barcaroli, D.4
Luthi, A.U.5
Pirnia, F.6
Hugli, B.7
Graber, H.U.8
De Laurenzi, V.9
Fey, M.F.10
-
44
-
-
0346725958
-
DeltaNp73beta is active in transactivation and growth suppression
-
Liu,G., Nozell,S., Xiao,H. and Chen,X. (2004) DeltaNp73beta is active in transactivation and growth suppression. Mol. Cell. Biol., 24, 487-501.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 487-501
-
-
Liu, G.1
Nozell, S.2
Xiao, H.3
Chen, X.4
-
45
-
-
0033406795
-
Deletion of the COOH-terminal region of p73alpha enhances both its transactivation function and DNA-binding activity but inhibits induction of apoptosis in mammalian cells
-
Ozaki,T., Naka,M., Takada,N., Tada,M., Sakiyama,S. and Nakagawara,A. (1999) Deletion of the COOH-terminal region of p73alpha enhances both its transactivation function and DNA-binding activity but inhibits induction of apoptosis in mammalian cells. Cancer Res., 59, 5902-5907.
-
(1999)
Cancer Res.
, vol.59
, pp. 5902-5907
-
-
Ozaki, T.1
Naka, M.2
Takada, N.3
Tada, M.4
Sakiyama, S.5
Nakagawara, A.6
-
46
-
-
0032793756
-
The p53 family: Same response, different signals?
-
Chen,X. (1999) The p53 family: Same response, different signals? Mol. Med. Today, 5, 387-392.
-
(1999)
Mol. Med. Today
, vol.5
, pp. 387-392
-
-
Chen, X.1
-
47
-
-
0033517321
-
New p73 variants with altered C-terminal structures have varied transcriptional activities
-
Ueda,Y., Hijikata,M., Takagi,S., Chiba,T. and Shimotohno,K. (1999) New p73 variants with altered C-terminal structures have varied transcriptional activities. Oncogene, 18, 4993-4998.
-
(1999)
Oncogene
, vol.18
, pp. 4993-4998
-
-
Ueda, Y.1
Hijikata, M.2
Takagi, S.3
Chiba, T.4
Shimotohno, K.5
-
48
-
-
0034628491
-
p73 transcriptional activity increases upon cooperation between its spliced forms
-
Alarcon-Vargas,D., Fuchs,S.Y., Deb,S. and Ronai,Z. (2000) p73 transcriptional activity increases upon cooperation between its spliced forms. Oncogene, 19, 831-835.
-
(2000)
Oncogene
, vol.19
, pp. 831-835
-
-
Alarcon-Vargas, D.1
Fuchs, S.Y.2
Deb, S.3
Ronai, Z.4
-
49
-
-
0033387525
-
Structure and function in the p53 family
-
Arrowsmith,C.H. (1999) Structure and function in the p53 family. Cell Death Differ., 6, 1169-1173.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1169-1173
-
-
Arrowsmith, C.H.1
-
50
-
-
0032533514
-
The potential tumor suppressor p73 differentially regulates cellular p53 target genes
-
Zhu,J., Jiang,J., Zhou,W. and Chen,X. (1998) The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res., 58, 5061-5065.
-
(1998)
Cancer Res.
, vol.58
, pp. 5061-5065
-
-
Zhu, J.1
Jiang, J.2
Zhou, W.3
Chen, X.4
-
51
-
-
0033595124
-
Promoter specificity and stability control of the p53-related protein p73
-
Lee,C.W. and La Thangue,N.B. (1999) Promoter specificity and stability control of the p53-related protein p73. Oncogene, 18, 4171-4181.
-
(1999)
Oncogene
, vol.18
, pp. 4171-4181
-
-
Lee, C.W.1
La Thangue, N.B.2
-
52
-
-
0037044799
-
Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses
-
Fontemaggi,G., Kela,I., Amariglio,N., Rechavi,G., Krishnamurthy,J., Strano,S., Sacchi,A., Givol,D. and Blandino,G. (2002) Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses. J. Biol. Chem., 277, 43359-43368.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43359-43368
-
-
Fontemaggi, G.1
Kela, I.2
Amariglio, N.3
Rechavi, G.4
Krishnamurthy, J.5
Strano, S.6
Sacchi, A.7
Givol, D.8
Blandino, G.9
-
53
-
-
2442494895
-
The common and distinct target genes of the p53 family transcription factors
-
Harms,K., Nozell,S. and Chen,X. (2004) The common and distinct target genes of the p53 family transcription factors. Cell. Mol. Life Sci., 61, 822-842.
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 822-842
-
-
Harms, K.1
Nozell, S.2
Chen, X.3
-
54
-
-
0041302159
-
Characterization of p73 functional domains necessary for transactivation and growth suppression
-
Nozell,S., Wu,Y., McNaughton,K., Liu,G., Willis,A., Paik,J.C. and Chen,X. (2003) Characterization of p73 functional domains necessary for transactivation and growth suppression. Oncogene, 22, 4333-4347.
-
(2003)
Oncogene
, vol.22
, pp. 4333-4347
-
-
Nozell, S.1
Wu, Y.2
McNaughton, K.3
Liu, G.4
Willis, A.5
Paik, J.C.6
Chen, X.7
-
55
-
-
10644270921
-
p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
-
Urist,M., Tanaka,T., Poyurovsky,M.V. and Prives,C. (2004) p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev., 18, 3041-3054.
-
(2004)
Genes Dev.
, vol.18
, pp. 3041-3054
-
-
Urist, M.1
Tanaka, T.2
Poyurovsky, M.V.3
Prives, C.4
-
56
-
-
0030877395
-
Functional dissection of p53 tumor suppressor protein
-
Jayaraman,L., Freulich,E. and Prives,C. (1997) Functional dissection of p53 tumor suppressor protein. Meth. Enzymol., 283, 245-256.
-
(1997)
Meth. Enzymol.
, vol.283
, pp. 245-256
-
-
Jayaraman, L.1
Freulich, E.2
Prives, C.3
-
57
-
-
0021895141
-
Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2?
-
Arslan,P., Di Virgilio,F., Beltrame,M., Tsien,R.Y. and Pozzan,T. (1985) Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2?. J. Biol. Chem., 260, 2719-2727.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 2719-2727
-
-
Arslan, P.1
Di Virgilio, F.2
Beltrame, M.3
Tsien, R.Y.4
Pozzan, T.5
-
58
-
-
0026708148
-
Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library
-
Stephen,C.W. and Lane,D.P. (1992) Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library. J. Mol. Biol., 225, 577-583.
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 577-583
-
-
Stephen, C.W.1
Lane, D.P.2
-
59
-
-
4444236656
-
Identification of a quinone-sensitive redox switch in the ArcB sensor kinase
-
Malpica,R., Franco,B., Rodriguez,C., Kwon,O. and Georgellis,D. (2004) Identification of a quinone-sensitive redox switch in the ArcB sensor kinase. Proc. Natl Acad. Sci. USA, 101, 13318-13323.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 13318-13323
-
-
Malpica, R.1
Franco, B.2
Rodriguez, C.3
Kwon, O.4
Georgellis, D.5
-
60
-
-
0034306245
-
p53 protein oxidation in cultured cells in response to pyrrolidine dithiocarbamate: A novel method for relating the amount of p53 oxidation in vivo to the regulation of p53-responsive genes
-
Wu,H.H., Thomas,J.A. and Momand,J. (2000) p53 protein oxidation in cultured cells in response to pyrrolidine dithiocarbamate: A novel method for relating the amount of p53 oxidation in vivo to the regulation of p53-responsive genes. Biochem. J., 351, 87-93.
-
(2000)
Biochem. J.
, vol.351
, pp. 87-93
-
-
Wu, H.H.1
Thomas, J.A.2
Momand, J.3
-
61
-
-
0029013621
-
Role of cysteine residues in regulation of p53 function
-
Rainwater,R., Parks,D., Anderson,M.E., Tegtmeyer,P. and Mann,K. (1995) Role of cysteine residues in regulation of p53 function. Mol. Cell. Biol., 15, 3892-3903.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3892-3903
-
-
Rainwater, R.1
Parks, D.2
Anderson, M.E.3
Tegtmeyer, P.4
Mann, K.5
-
62
-
-
0028124972
-
Mutation of conserved domain II alters the sequence specificity of DNA binding by the p53 protein
-
Freeman,J., Schmidt,S., Scharer,E. and Iggo,R. (1994) Mutation of conserved domain II alters the sequence specificity of DNA binding by the p53 protein. EMBO J., 13, 5393-5400.
-
(1994)
EMBO J.
, vol.13
, pp. 5393-5400
-
-
Freeman, J.1
Schmidt, S.2
Scharer, E.3
Iggo, R.4
-
63
-
-
33746012703
-
Mutational analysis of the p53 core domain L1 loop
-
Zupnick,A. and Prives,C. (2006) Mutational analysis of the p53 core domain L1 loop. J. Biol. Chem., 281, 20464-20473.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 20464-20473
-
-
Zupnick, A.1
Prives, C.2
-
64
-
-
4444383214
-
Regulation of DNA binding of p53 by its C-terminal domain
-
Weinberg,R.L., Freund,S.M., Veprintsev,D.B., Bycroft,M. and Fersht,A.R. (2004) Regulation of DNA binding of p53 by its C-terminal domain. J. Mol. Biol., 342, 801-811.
-
(2004)
J. Mol. Biol.
, vol.342
, pp. 801-811
-
-
Weinberg, R.L.1
Freund, S.M.2
Veprintsev, D.B.3
Bycroft, M.4
Fersht, A.R.5
-
65
-
-
33144474649
-
Solution structure of p53 core domain: Structural basis for its instability
-
Canadillas,J.M., Tidow,H., Freund,S.M., Rutherford,T.J., Ang,H.C. and Fersht,A.R. (2006) Solution structure of p53 core domain: Structural basis for its instability. Proc. Natl Acad. Sci. USA, 103, 2109-2114.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 2109-2114
-
-
Canadillas, J.M.1
Tidow, H.2
Freund, S.M.3
Rutherford, T.J.4
Ang, H.C.5
Fersht, A.R.6
-
66
-
-
4644362728
-
Role of copper in tumour angiogenesis-clinical implications
-
Nasulewicz,A., Mazur,A. and Opolski,A. (2004) Role of copper in tumour angiogenesis-clinical implications. J. Trace Elem. Med. Biol., 18, 1-8.
-
(2004)
J. Trace Elem. Med. Biol.
, vol.18
, pp. 1-8
-
-
Nasulewicz, A.1
Mazur, A.2
Opolski, A.3
-
67
-
-
25144462051
-
The tumor suppressor protein p53 functions similarly to p63 and p73 in activating transcription in vitro
-
Mondal,N. and Parvin,J.D. (2005) The tumor suppressor protein p53 functions similarly to p63 and p73 in activating transcription in vitro. Cancer Biol. Ther., 4, 414-418.
-
(2005)
Cancer Biol. Ther.
, vol.4
, pp. 414-418
-
-
Mondal, N.1
Parvin, J.D.2
-
68
-
-
0037130473
-
P53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop
-
Kartasheva,N.N., Contente,A., Lenz-Stoppler,C., Roth,J. and Dobbelstein,M. (2002) p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop. Oncogene, 21, 4715-4727.
-
(2002)
Oncogene
, vol.21
, pp. 4715-4727
-
-
Kartasheva, N.N.1
Contente, A.2
Lenz-Stoppler, C.3
Roth, J.4
Dobbelstein, M.5
-
69
-
-
0035808390
-
P300 does not require its acetylase activity to stimulate p73 function
-
Zeng,X., Lee,H., Zhang,Q. and Lu,H. (2001) p300 does not require its acetylase activity to stimulate p73 function. J. Biol. Chem., 276, 48-52.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48-52
-
-
Zeng, X.1
Lee, H.2
Zhang, Q.3
Lu, H.4
-
70
-
-
0036510750
-
HMGB1 and HMGB2 cell-specifically down-regulate the p53-and p73-dependent sequence-specific transactivation from the human Bax gene promoter
-
Stros,M., Ozaki,T., Bacikova,A., Kageyama,H. and Nakagawara,A. (2002) HMGB1 and HMGB2 cell-specifically down-regulate the p53-and p73-dependent sequence-specific transactivation from the human Bax gene promoter. J. Biol. Chem., 277, 7157-7164.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7157-7164
-
-
Stros, M.1
Ozaki, T.2
Bacikova, A.3
Kageyama, H.4
Nakagawara, A.5
-
71
-
-
29044443253
-
A novel response element confers p63- and p73-specific activation of the WNT4 promoter
-
Osada,M., Park,H.L., Nagakawa,Y., Begum,S., Yamashita,K, Wu,G., Kim,M.S., Trink,B. and Sidransky,D. (2006) A novel response element confers p63- and p73-specific activation of the WNT4 promoter. Biochem. Biophys. Res. Commun., 339, 1120-1128.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.339
, pp. 1120-1128
-
-
Osada, M.1
Park, H.L.2
Nagakawa, Y.3
Begum, S.4
Yamashita, K.5
Wu, G.6
Kim, M.S.7
Trink, B.8
Sidransky, D.9
-
72
-
-
2542584623
-
Promoter-specific p53-dependent histone acetylation following DNA damage
-
Kaeser,M.D. and Iggo,R.D. (2004) Promoter-specific p53-dependent histone acetylation following DNA damage. Oncogene, 23, 4007-4013.
-
(2004)
Oncogene
, vol.23
, pp. 4007-4013
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
73
-
-
0035858984
-
P53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements
-
Campomenosi,P., Monti,P., Aprile,A., Abbondandolo,A., Frebourg,T., Gold,B., Crook,T., Inga,A., Resnick,M.A., Iggo,R. et al. (2001) p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements. Oncogene, 20, 3573-3579.
-
(2001)
Oncogene
, vol.20
, pp. 3573-3579
-
-
Campomenosi, P.1
Monti, P.2
Aprile, A.3
Abbondandolo, A.4
Frebourg, T.5
Gold, B.6
Crook, T.7
Inga, A.8
Resnick, M.A.9
Iggo, R.10
-
74
-
-
0037066755
-
Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative effect
-
Nicholls,C.D., McLure,K.G., Shields,M.A. and Lee,P.W. (2002) Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative effect. J. Biol. Chem., 277, 12937-12945.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12937-12945
-
-
Nicholls, C.D.1
McLure, K.G.2
Shields, M.A.3
Lee, P.W.4
|