메뉴 건너뛰기




Volumn 9, Issue 10, 2014, Pages

P2x7 receptor modulates inflammatory and functional pulmonary changes induced by silica

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; COLLAGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; NITRIC OXIDE; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2X7 RECEPTOR ANTAGONIST; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84907937862     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110185     Document Type: Article
Times cited : (61)

References (46)
  • 1
    • 84861456689 scopus 로고    scopus 로고
    • Silicosis
    • S0140-6736(12)60235-9 [pii]
    • Leung CC, Yu IT, Chen W (2012) Silicosis. Lancet 379: 2008-2018. S0140-6736(12)60235-9 [pii];10.1016/S0140-6736(12)60235-9 [doi].
    • (2012) Lancet , vol.379 , pp. 2008-2018
    • Leung, C.C.1    Yu, I.T.2    Chen, W.3
  • 2
    • 84870514546 scopus 로고    scopus 로고
    • ATP release and purinergic signaling: A common pathway for particle-mediated inflammasome activation
    • cddis2012144 [pii]
    • Riteau N, Baron L, Villeret B, Guillou N, Savigny F, et al. (2012) ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation. Cell Death Dis 3: e403. cddis2012144 [pii];10.1038/cddis.2012.144 [doi].
    • (2012) Cell Death Dis , vol.3 , pp. 403
    • Riteau, N.1    Baron, L.2    Villeret, B.3    Guillou, N.4    Savigny, F.5
  • 3
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • 1156995 [pii]
    • Dostert C, Petrilli V, Van BR, Steele C, Mossman BT, et al. (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677. 1156995 [pii];10.1126/science.1156995 [doi].
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van, B.R.3    Steele, C.4    Mossman, B.T.5
  • 4
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • ni.1631 [pii]
    • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, et al. (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847-856. ni.1631 [pii];10.1038/ni.1631 [doi].
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5
  • 6
    • 79955957628 scopus 로고    scopus 로고
    • P2X receptors in health and disease
    • B978-0-12-385526-8.00011-4 [pii] 10.1016/B978-0-12-385526-8.00011-4
    • Burnstock G, Kennedy C (2011) P2X receptors in health and disease. Adv Pharmacol 61: 333-372. B978-0-12-385526-8.00011-4 [pii];10.1016/B978-0-12-385526-8.00011-4 [doi].
    • (2011) Adv Pharmacol , vol.61 , pp. 333-372
    • Burnstock, G.1    Kennedy, C.2
  • 7
    • 80555140059 scopus 로고    scopus 로고
    • The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells
    • PONE-D-11-11625 [pii]
    • Belete HA, Hubmayr RD, Wang S, Singh RD (2011) The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells. PLoS One 6: e27469. 10.1371/journal.pone.0027469 [doi];- PONE-D-11-11625 [pii].
    • (2011) PLoS One , vol.6 , pp. 27469
    • Belete, H.A.1    Hubmayr, R.D.2    Wang, S.3    Singh, R.D.4
  • 8
    • 77957101431 scopus 로고    scopus 로고
    • Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis
    • 201003-0359OC [pii]
    • Riteau N, Gasse P, Fauconnier L, Gombault A, Couegnat M, et al. (2010) Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis. Am J Respir Crit Care Med 182: 774-783. 201003-0359OC [pii];10.1164/rccm.201003-0359OC [doi].
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 774-783
    • Riteau, N.1    Gasse, P.2    Fauconnier, L.3    Gombault, A.4    Couegnat, M.5
  • 9
    • 84867095238 scopus 로고    scopus 로고
    • P2x7 receptor activation induces inflammatory responses in salivary gland epithelium
    • Woods LT, Camden JM, Batek JM, Petris MJ, Erb L, et al. (2012) P2X7 receptor activation induces inflammatory responses in salivary gland epithelium. Am J Physiol Cell Physiol 303: C790-C801.
    • (2012) Am J Physiol Cell Physiol , vol.303 , pp. C790-C801
    • Woods, L.T.1    Camden, J.M.2    Batek, J.M.3    Petris, M.J.4    Erb, L.5
  • 11
    • 80052482830 scopus 로고    scopus 로고
    • P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke
    • ;PONE-D-11-05373 [pii]
    • Eltom S, Stevenson CS, Rastrick J, Dale N, Raemdonck K, et al. (2011) P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke. PLoS One 6: e24097. 10.1371/journal.-pone.0024097 [doi];PONE-D-11-05373 [pii].
    • (2011) PLoS One , vol.6 , pp. 24097
    • Eltom, S.1    Stevenson, C.S.2    Rastrick, J.3    Dale, N.4    Raemdonck, K.5
  • 12
    • 79952218099 scopus 로고    scopus 로고
    • P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema
    • 2010-0038OC [pii]
    • Lucattelli M, Cicko S, Muller T, Lommatzsch M, De CG, et al. (2011) P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema. Am J Respir Cell Mol Biol 44: 423-429. 2010-0038OC [pii];10.1165/rcmb.2010-0038OC [doi].
    • (2011) Am J Respir Cell Mol Biol , vol.44 , pp. 423-429
    • Lucattelli, M.1    Cicko, S.2    Muller, T.3    Lommatzsch, M.4    De, C.G.5
  • 13
    • 60749087353 scopus 로고    scopus 로고
    • Attenuated P2X7 pore function as a risk factor for virus-induced loss of asthma control
    • 200802-293OC [pii]
    • Denlinger LC, Shi L, Guadarrama A, Schell K, Green D, et al. (2009) Attenuated P2X7 pore function as a risk factor for virus-induced loss of asthma control. Am J Respir Crit Care Med 179: 265-270. 200802-293OC [pii];10.1164/rccm.200802-293OC [doi].
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 265-270
    • Denlinger, L.C.1    Shi, L.2    Guadarrama, A.3    Schell, K.4    Green, D.5
  • 14
    • 80052422394 scopus 로고    scopus 로고
    • Activation of P2Y1 and P2Y2 receptors induces chloride secretion via calcium-activated chloride channels in kidney inner medullary collecting duct cells
    • ajprenal.00709.2010 [pii] s0709.2010
    • Rajagopal M, Kathpalia PP, Thomas SV, Pao AC (2011) Activation of P2Y1 and P2Y2 receptors induces chloride secretion via calcium-activated chloride channels in kidney inner medullary collecting duct cells. Am J Physiol Renal Physiol 301: F544-F553. ajprenal.00709.2010 [pii];10.1152/ajprenal. 00709.2010 [doi].
    • (2011) Am J Physiol Renal Physiol , vol.301 , pp. F544-F553
    • Rajagopal, M.1    Kathpalia, P.P.2    Thomas, S.V.3    Pao, A.C.4
  • 15
    • 54049094727 scopus 로고    scopus 로고
    • Coupling of airway ciliary activity and mucin secretion to mechanical stresses by purinergic signaling
    • S1569-9048(08)00140-7 [pii]
    • Davis CW, Lazarowski E (2008) Coupling of airway ciliary activity and mucin secretion to mechanical stresses by purinergic signaling. Respir Physiol Neurobiol 163: 208-213. S1569-9048(08)00140-7 [pii];10.1016/j.resp.2008.05.015 [doi].
    • (2008) Respir Physiol Neurobiol , vol.163 , pp. 208-213
    • Davis, C.W.1    Lazarowski, E.2
  • 16
    • 0000582524 scopus 로고    scopus 로고
    • Revised Guide for the Care and Use of Laboratory Animals available
    • Physiologist 199 211
    • Bayne K (1996) Revised Guide for the Care and Use of Laboratory Animals available. American Physiological Society. Physiologist 39: 199, 208-199, 211.
    • (1996) American Physiological Society , vol.39 , pp. 208-1199
    • Bayne, K.1
  • 17
    • 0022256369 scopus 로고
    • Analysis of the behavior of the respiratory system with constant inspiratory flow
    • Bates JH, Rossi A, Milic-Emili J (1985) Analysis of the behavior of the respiratory system with constant inspiratory flow. J Appl Physiol 58: 1840-1848.
    • (1985) J Appl Physiol , vol.58 , pp. 1840-1848
    • Bates, J.H.1    Rossi, A.2    Milic-Emili, J.3
  • 18
    • 33750201396 scopus 로고    scopus 로고
    • The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice
    • 5001804 [pii]
    • Goncalves RG, Gabrich L, Rosario A Jr, Takiya CM, Ferreira ML, et al. (2006) The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice. Kidney Int 70: 1599-1606. 5001804 [pii];10.1038/sj.ki.5001804 [doi].
    • (2006) Kidney Int , vol.70 , pp. 1599-1606
    • Goncalves, R.G.1    Gabrich, L.2    Rosario, A.3    Takiya, C.M.4    Ferreira, M.L.5
  • 21
    • 0035107552 scopus 로고    scopus 로고
    • Lung tissue mechanics and extracellular matrix composition in a murine model of silicosis
    • Faffe DS, Silva GH, Kurtz PM, Negri EM, Capelozzi VL,et al. (2001) Lung tissue mechanics and extracellular matrix composition in a murine model of silicosis. J Appl Physiol 90: 1400-1406.
    • (2001) J Appl Physiol , vol.90 , pp. 1400-1406
    • Faffe, D.S.1    Silva, G.H.2    Kurtz, P.M.3    Negri, E.M.4    Capelozzi, V.L.5
  • 22
    • 66249123631 scopus 로고    scopus 로고
    • Systemic inhibition of nf-kappab activation protects from silicosis
    • Di Giuseppe M, Gambelli F, Hoyle GW, Lungarella G, Studer SM, et al. (2009) Systemic inhibition of NF-kappaB activation protects from silicosis. PLoS One 4: e5689. 10.1371/journal.pone.0005689 [doi].
    • (2009) PLoS One , vol.4 , pp. e5689
    • Di Giuseppe, M.1    Gambelli, F.2    Hoyle, G.W.3    Lungarella, G.4    Studer, S.M.5
  • 23
    • 0031425953 scopus 로고    scopus 로고
    • Extracellular ATP activates transcription factor nf-kappab through the p2z purinoreceptor by selectively targeting nf-kappab p65
    • Ferrari D, Wesselborg S, Bauer MK, Schulze-Osthoff K (1997) Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65. J Cell Biol 139: 1635-1643.
    • (1997) J Cell Biol , vol.139 , pp. 1635-1643
    • Ferrari, D.1    Wesselborg, S.2    Bauer, M.K.3    Schulze-Osthoff, K.4
  • 24
    • 60449100436 scopus 로고    scopus 로고
    • Selective P2X(7) receptor antagonists for chronic inflammation and pain
    • Carroll WA, Donnelly-Roberts D, Jarvis MF (2009) Selective P2X(7) receptor antagonists for chronic inflammation and pain. Purinergic Signal 5: 63-73. 10.1007/s11302-008-9110-6 [doi].
    • (2009) Purinergic Signal , vol.5 , pp. 63-73
    • Carroll, W.A.1    Donnelly-Roberts, D.2    Jarvis, M.F.3
  • 25
    • 33746701380 scopus 로고    scopus 로고
    • P2X receptors as cell-surface ATP sensors in health and disease
    • nature04886
    • Khakh BS, North RA (2006) P2X receptors as cell-surface ATP sensors in health and disease. Nature 442: 527-532. nature04886 [pii];10.1038/nature04886 [doi].
    • (2006) Nature , vol.442 , pp. 527-532
    • Khakh, B.S.1    North, R.A.2
  • 26
    • 83455233679 scopus 로고    scopus 로고
    • Cell death in the pathogenesis of immune-mediated diseases: The role of HMGB1 and DAMP-PAMP complexes
    • smw-13256
    • Pisetsky D (2011) Cell death in the pathogenesis of immune-mediated diseases: the role of HMGB1 and DAMP-PAMP complexes. Swiss Med Wkly 141: w13256. smw-13256 [pii];10.4414/smw.2011.13256 [doi].
    • (2011) Swiss Med Wkly , vol.141 , pp. 13256
    • Pisetsky, D.1
  • 27
    • 34548857335 scopus 로고    scopus 로고
    • Inside, outside, upside down: Damage-associated molecular-pattern molecules (DAMPs) and redox
    • S1471-4906(07)00207-4
    • Rubartelli A, Lotze MT (2007) Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox. Trends Immunol 28: 429-436. S1471-4906(07)00207-4 [pii];10.1016/j.it.2007.08.004 [doi].
    • (2007) Trends Immunol , vol.28 , pp. 429-436
    • Rubartelli, A.1    Lotze, M.T.2
  • 28
    • 84875013455 scopus 로고    scopus 로고
    • P2x7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis
    • da Silva GL, Sperotto ND, Borges TJ, Bonorino C, Takyia CM, et al. (2013) P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis. Exp Dermatol 22: 184-188.
    • (2013) Exp Dermatol , vol.22 , pp. 184-188
    • Da Silva, G.L.1    Sperotto, N.D.2    Borges, T.J.3    Bonorino, C.4    Takyia, C.M.5
  • 29
    • 0036659510 scopus 로고    scopus 로고
    • Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X(7)
    • Aga M, Johnson CJ, Hart AP, Guadarrama AG, Suresh M, et al. (2002) Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X(7). J Leukoc Biol 72: 222-232.
    • (2002) J Leukoc Biol , vol.72 , pp. 222-232
    • Aga, M.1    Johnson, C.J.2    Hart, A.P.3    Guadarrama, A.G.4    Suresh, M.5
  • 30
    • 0035808396 scopus 로고    scopus 로고
    • Altered cytokine production in mice lacking P2X(7) receptors
    • M006781200 [pii]
    • Solle M, Labasi J, Perregaux DG, Stam E, Petrushova N, et al. (2001) Altered cytokine production in mice lacking P2X(7) receptors. J Biol Chem 276: 125-132. 10.1074/jbc.M006781200 [doi];M006781200 [pii].
    • (2001) J Biol Chem , vol.276 , pp. 125-132
    • Solle, M.1    Labasi, J.2    Perregaux, D.G.3    Stam, E.4    Petrushova, N.5
  • 31
    • 67349098560 scopus 로고    scopus 로고
    • Cell signaling via the P2X(7) nucleotide receptor: Linkage to ROS production, gene transcription, and receptor trafficking
    • Lenertz LY, Gavala ML, Hill LM, Bertics PJ (2009) Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking. Purinergic Signal 5: 175-187. 10.1007/s11302-009-9133-7 [doi].
    • (2009) Purinergic Signal , vol.5 , pp. 175-187
    • Lenertz, L.Y.1    Gavala, M.L.2    Hill, L.M.3    Bertics, P.J.4
  • 32
    • 0038359740 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
    • S0891584903001497 [pii].
    • Fubini B, Hubbard A (2003) Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med 34: 1507-1516. S0891584903001497 [pii].
    • (2003) Free Radic Biol Med , vol.34 , pp. 1507-1516
    • Fubini, B.1    Hubbard, A.2
  • 33
    • 0029160229 scopus 로고
    • Extrace llular ATP enhances mRNA levels of nitric oxide synthase and TNF-alpha in lipopolysac-charide-treated RAW 264.7 murine macrophages
    • S0006291X85722656 [pii]
    • Tonetti M, Sturla L, Giovine M, Benatti U, De FA (1995) Extracellular ATP enhances mRNA levels of nitric oxide synthase and TNF-alpha in lipopolysac-charide-treated RAW 264.7 murine macrophages. Biochem Biophys Res Commun 214: 125-130. S0006291X85722656 [pii].
    • (1995) Biochem Biophys Res Commun , vol.214 , pp. 125-130
    • Tonetti, M.1    Sturla, L.2    Giovine, M.3    Benatti, U.4    De, F.A.5
  • 34
    • 0038460816 scopus 로고    scopus 로고
    • Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line
    • 323-330. S0378427403001930 [pii]
    • Cho H, Lee J, Kwak NJ, Lee KH, Rha S, et al. (2003) Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line. Toxicol Lett 143: 323-330. S0378427403001930 [pii].
    • (2003) Toxicol Lett , vol.143
    • Cho, H.1    Lee, J.2    Kwak, N.J.3    Lee, K.H.4    Rha, S.5
  • 35
    • 34548411746 scopus 로고    scopus 로고
    • TGF-beta-induced EMT: Mechanisms and implications for fibrotic lung disease
    • 00163.2007 [pii]
    • Willis BC, Borok Z (2007) TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease. Am J Physiol Lung Cell Mol Physiol 293: L525-L534. 00163.2007 [pii];10.1152/ajplung.00163.2007 [doi].
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293 , pp. L525-L534
    • Willis, B.C.1    Borok, Z.2
  • 37
    • 0025302767 scopus 로고
    • Regulation of human lung fibroblast collagen production by recombinant interleukin-1, tumor necrosis factor, and interferon-gamma
    • Elias JA, Freundlich B, Adams S, Rosenbloom J (1990) Regulation of human lung fibroblast collagen production by recombinant interleukin-1, tumor necrosis factor, and interferon-gamma. Ann N Y Acad Sci 580: 233-244.
    • (1990) Ann N Y Acad Sci , vol.580 , pp. 233-244
    • Elias, J.A.1    Freundlich, B.2    Adams, S.3    Rosenbloom, J.4
  • 38
    • 47849132947 scopus 로고    scopus 로고
    • The Nalp3 inflammasome is essential for the development of silicosis
    • 0803933105 [pii]
    • Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, et al. (2008) The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A 105: 9035-9040. 0803933105 [pii];10.1073/pnas.0803933105 [doi].
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 9035-9040
    • Cassel, S.L.1    Eisenbarth, S.C.2    Iyer, S.S.3    Sadler, J.J.4    Colegio, O.R.5
  • 39
    • 34548444551 scopus 로고    scopus 로고
    • Liaisons dangereuses: P2X(7) and the inflammasome
    • S0165-6147(07)00184-8 [pii]
    • Di Virgilio F (2007) Liaisons dangereuses: P2X(7) and the inflammasome. Trends Pharmacol Sci 28: 465-472. S0165-6147(07)00184-8 [pii];10.1016/j.tips.2007.07.002 [doi].
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 465-472
    • Di Virgilio, F.1
  • 40
    • 84898480330 scopus 로고    scopus 로고
    • The role of the inflammasome in fibrotic respiratory diseases
    • Rastrick J, Birrell M (2014) The role of the inflammasome in fibrotic respiratory diseases. Minerva Med 105: 9-23.
    • (2014) Minerva Med , vol.105 , pp. 9-23
    • Rastrick, J.1    Birrell, M.2
  • 41
    • 33646072818 scopus 로고    scopus 로고
    • The P2X7 receptor: A key player in IL-1 processing and release
    • 176/7/3877 [pii]
    • Ferrari D, Pizzirani C, Adinolfi E, Lemoli RM, Curti A, et al. (2006) The P2X7 receptor: a key player in IL-1 processing and release. J Immunol 176: 3877-3883. 176/7/3877 [pii].
    • (2006) J Immunol , vol.176 , pp. 3877-3883
    • Ferrari, D.1    Pizzirani, C.2    Adinolfi, E.3    Lemoli, R.M.4    Curti, A.5
  • 42
    • 79961139550 scopus 로고    scopus 로고
    • TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions
    • CS2011 0086 [pii]
    • Santibanez JF, Quintanilla M, Bernabeu C (2011) TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions. Clin Sci (Lond) 121: 233-251. CS20110086 [pii];10.1042/CS20110086 [doi].
    • (2011) Clin Sci (Lond) , vol.121 , pp. 233-251
    • Santibanez, J.F.1    Quintanilla, M.2    Bernabeu, C.3
  • 43
    • 79960967247 scopus 로고    scopus 로고
    • Cross-talk of the related bioactivity mediators in serum after injection of soluble TNF-alpha receptor on silicosis model of rats
    • 0748233710393778 [pii]
    • Gao HS, Rong X, Peng D, Chen NF, Bing M, et al. (2011) Cross-talk of the related bioactivity mediators in serum after injection of soluble TNF-alpha receptor on silicosis model of rats. Toxicol Ind Health 27: 607-616. 0748233710393778 [pii];10.1177/0748233710393778 [doi].
    • (2011) Toxicol Ind Health , vol.27 , pp. 607-616
    • Gao, H.S.1    Rong, X.2    Peng, D.3    Chen, N.F.4    Bing, M.5
  • 44
    • 84861532288 scopus 로고    scopus 로고
    • A new role for the p2x7 receptor: A scavenger receptor for bacteria and apoptotic cells in the absence of serum and extracellular atp
    • Wiley JS, Gu BJ (2012) A new role for the P2X7 receptor: a scavenger receptor for bacteria and apoptotic cells in the absence of serum and extracellular ATP. Purinergic Signal 8: 579-586.
    • (2012) Purinergic Signal , vol.8 , pp. 579-586
    • Wiley, J.S.1    Gu, B.J.2
  • 45
    • 84877146553 scopus 로고    scopus 로고
    • Silica phagocytosis causes apoptosis and necrosis by different temporal and molecular pathways in alveolar macrophages
    • Joshi GN, Knecht DA (2013) Silica phagocytosis causes apoptosis and necrosis by different temporal and molecular pathways in alveolar macrophages. Apoptosis 18: 271-285.
    • (2013) Apoptosis , vol.18 , pp. 271-285
    • Joshi, G.N.1    Knecht, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.