The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Belete, Hewan A ^a   Hubmayr, Rolf D ^a   Wang, Shaohua ^a   Singh, Raman Deep ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PURINERGIC P2Y2 RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COMMUNICATION; CELL DAMAGE; CELL MEMBRANE; CELL PROTECTION; CELL REGENERATION; CELL STRESS; CONTROLLED STUDY; EXOCYTOSIS; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; METABOLITE; NONHUMAN; PURINERGIC SIGNALING; RAT; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECT; EPITHELIUM CELL; IMMUNOLOGY; INFLAMMATION; INNATE IMMUNITY; LUNG ALVEOLUS; METABOLISM; PATHOLOGY; WOUND HEALING;

RATTUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; EPITHELIAL CELLS; IMMUNITY, INNATE; INFLAMMATION; PULMONARY ALVEOLI; RATS; RECEPTORS, PURINERGIC P2Y2; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 80555140059     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027469     Document Type: Article

References (70)

1. Shen SS, Tucker WC, Chapman ER, Steinhardt RA, (2005) Molecular regulation of membrane resealing in 3T3 fibroblasts. J Biol Chem 280: 1652-1660.
2. Dreyfuss D, Saumon G, (1998) Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 157: 294-323.
3. Vlahakis NE, Hubmayr RD, (2005) Cellular stress failure in ventilator-injured lungs. Am J Respir Crit Care Med 171: 1328-1342.
4. Gattinoni L, Carlesso E, Cressoni M, (2011) Assessing gas exchange in acute lung injury/acute respiratory distress syndrome: diagnostic techniques and prognostic relevance. Curr Opin Crit Care 17: 18-23.
5. Wheeler AP, Bernard GR, (2007) Acute lung injury and the acute respiratory distress syndrome: a clinical review. Lancet 369: 1553-1564.
6. Nieuwenhuizen L, de Groot PG, Grutters JC, Biesma DH, (2009) A review of pulmonary coagulopathy in acute lung injury, acute respiratory distress syndrome and pneumonia. Eur J Haematol 82: 413-425.
7. Gajic O, Lee J, Doerr CH, Berrios JC, Myers JL, et al. (2003) Ventilator-induced cell wounding and repair in the intact lung. Am J Respir Crit Care Med 167: 1057-1063.
8. Grembowicz KP, Sprague D, McNeil PL, (1999) Temporary disruption of the plasma membrane is required for c-fos expression in response to mechanical stress. Mol Biol Cell 10: 1247-1257.
9. Tremblay LN, Slutsky AS, (1998) Ventilator-induced injury: from barotrauma to biotrauma. Proc Assoc Am Physicians 110: 482-488.
10. Godin LM, Vergen J, Prakash YS, Pagano RE, Hubmayr RD, (2011) Spatiotemporal Dynamics of Actin Remodeling and Endomembrane Trafficking in Alveolar Epithelial Type I Cell Wound Healing. Am J Physiol Lung Cell Mol Physiol.
11. McNeil PL, Steinhardt RA, (2003) Plasma membrane disruption: repair, prevention, adaptation. Annu Rev Cell Dev Biol 19: 697-731.
12. Tam C, Idone V, Devlin C, Fernandes MC, Flannery A, et al. (2010) Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair. J Cell Biol 189: 1027-1038.
13. Jung SR, Kim MH, Hille B, Nguyen TD, Koh DS, (2004) Regulation of exocytosis by purinergic receptors in pancreatic duct epithelial cells. Am J Physiol Cell Physiol 286: C573-579.
14. Patel AS, Reigada D, Mitchell CH, Bates SR, Margulies SS, et al. (2005) Paracrine stimulation of surfactant secretion by extracellular ATP in response to mechanical deformation. Am J Physiol Lung Cell Mol Physiol 289: L489-496.
15. Ahmad S, Ahmad A, McConville G, Schneider BK, Allen CB, et al. (2005) Lung epithelial cells release ATP during ozone exposure: signaling for cell survival. Free Radic Biol Med 39: 213-226.
16. Douillet CD, Robinson WP 3rd, Zarzaur BL, Lazarowski ER, Boucher RC, et al. (2005) Mechanical ventilation alters airway nucleotides and purinoceptors in lung and extrapulmonary organs. Am J Respir Cell Mol Biol 32: 52-58.
17. Corriden R, Insel PA, (2010) Basal release of ATP: an autocrine-paracrine mechanism for cell regulation. Sci Signal 3: re1.
18. Correa-Meyer E, Pesce L, Guerrero C, Sznajder JI, (2002) Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 282: L883-891.
19. Togo T, Alderton JM, Steinhardt RA, (2003) Long-term potentiation of exocytosis and cell membrane repair in fibroblasts. Mol Biol Cell 14: 93-106.
20. Burnstock G, (2006) Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev 58: 58-86.
21. Abbracchio MP, Burnstock G, Boeynaems JM, Barnard EA, Boyer JL, et al. (2006) International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev 58: 281-341.
22. dos Santos CC, Han B, Andrade CF, Bai X, Uhlig S, et al. (2004) DNA microarray analysis of gene expression in alveolar epithelial cells in response to TNFalpha, LPS, and cyclic stretch. Physiol Genomics 19: 331-342.
23. Pugin J, (2003) Molecular mechanisms of lung cell activation induced by cyclic stretch. Crit Care Med 31: S200-206.
24. da Cruz CM, Ventura AL, Schachter J, Costa-Junior HM, da Silva Souza HA, et al. (2006) Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. Br J Pharmacol 147: 324-334.
25. Ralevic V, Burnstock G, (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50: 413-492.
26. Wesley UV, Bove PF, Hristova M, McCarthy S, van der Vliet A, (2007) Airway epithelial cell migration and wound repair by ATP-mediated activation of dual oxidase 1. J Biol Chem 282: 3213-3220.
27. Reddy A, Caler EV, Andrews NW, (2001) Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes. Cell 106: 157-169.
28. Ware LB, Matthay MA, (2000) The acute respiratory distress syndrome. N Engl J Med 342: 1334-1349.
29. Halbertsma FJ, Vaneker M, Scheffer GJ, van der Hoeven JG, (2005) Cytokines and biotrauma in ventilator-induced lung injury: a critical review of the literature. Neth J Med 63: 382-392.
30. dos Santos CC, Slutsky AS, (2006) The contribution of biophysical lung injury to the development of biotrauma. Annu Rev Physiol 68: 585-618.
31. Covian-Nares JF, Koushik SV, Puhl HL 3rd, Vogel SS, (2010) Membrane wounding triggers ATP release and dysferlin-mediated intercellular calcium signaling. J Cell Sci 123: 1884-1893.
32. Wang EC, Lee JM, Ruiz WG, Balestreire EM, von Bodungen M, et al. (2005) ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells. J Clin Invest 115: 2412-2422.
33. Li J, Liu D, Ke HZ, Duncan RL, Turner CH, (2005) The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J Biol Chem 280: 42952-42959.
34. Liu D, Genetos DC, Shao Y, Geist DJ, Li J, et al. (2008) Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts. Bone 42: 644-652.
35. Kiefmann R, Islam MN, Lindert J, Parthasarathi K, Bhattacharya J, (2009) Paracrine purinergic signaling determines lung endothelial nitric oxide production. Am J Physiol Lung Cell Mol Physiol 296: L901-910.
36. Rossi AH, Salmon WC, Chua M, Davis CW, (2007) Calcium signaling in human airway goblet cells following purinergic activation. Am J Physiol Lung Cell Mol Physiol 292: L92-98.
37. Adriaensen D, Timmermans JP, (2004) Purinergic signalling in the lung: important in asthma and COPD? Curr Opin Pharmacol 4: 207-214.
38. Goding JW, (2000) Ecto-enzymes: physiology meets pathology. J Leukoc Biol 67: 285-311.
39. Homolya L, Steinberg TH, Boucher RC, (2000) Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia. J Cell Biol 150: 1349-1360.
40. Rice WR, Burton FM, Fiedeldey DT, (1995) Cloning and expression of the alveolar type II cell P2u-purinergic receptor. Am J Respir Cell Mol Biol 12: 27-32.
41. Gozal E, Forman HJ, Torres M, (2001) ADP stimulates the respiratory burst without activation of ERK and AKT in rat alveolar macrophages. Free Radic Biol Med 31: 679-687.
42. Vlahakis NE, Schroeder MA, Pagano RE, Hubmayr RD, (2001) Deformation-induced lipid trafficking in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 280: L938-946.
43. Vlahakis NE, Schroeder MA, Pagano RE, Hubmayr RD, (2002) Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure. Am J Respir Crit Care Med 166: 1282-1289.
44. Zhang Z, Chen G, Zhou W, Song A, Xu T, et al. (2007) Regulated ATP release from astrocytes through lysosome exocytosis. Nat Cell Biol 9: 945-953.
45. Beigi RD, Dubyak GR, (2000) Endotoxin activation of macrophages does not induce ATP release and autocrine stimulation of P2 nucleotide receptors. J Immunol 165: 7189-7198.
46. Lazarowski ER, Harden TK, (1999) Quantitation of extracellular UTP using a sensitive enzymatic assay. Br J Pharmacol 127: 1272-1278.
47. Lazarowski ER, Boucher RC, Harden TK, (2000) Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations. J Biol Chem 275: 31061-31068.
48. McNeil PL, (2002) Repairing a torn cell surface: make way, lysosomes to the rescue. J Cell Sci 115: 873-879.
49. Terasaki M, Miyake K, McNeil PL, (1997) Large plasma membrane disruptions are rapidly resealed by Ca2+-dependent vesicle-vesicle fusion events. J Cell Biol 139: 63-74.
50. Liu GJ, Werry EL, Bennett MR, (2005) Secretion of ATP from Schwann cells in response to uridine triphosphate. Eur J Neurosci 21: 151-160.
51. Sugamoto Y, Hirai K, Tokoro T, (1999) P2Y2 receptor elevates intracellular calcium concentration in rabbit eye suprachoroid. J Med Dent Sci 46: 83-92.
52. Seino S, Shibasaki T, (2005) PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis. Physiol Rev 85: 1303-1342.
53. Orihuela PA, Parada-Bustamante A, Zuniga LM, Croxatto HB, (2006) Inositol triphosphate participates in an oestradiol nongenomic signalling pathway involved in accelerated oviductal transport in cycling rats. J Endocrinol 188: 579-588.
54. Schrader AM, Camden JM, Weisman GA, (2005) P2Y2 nucleotide receptor up-regulation in submandibular gland cells from the NOD.B10 mouse model of Sjogren's syndrome. Arch Oral Biol 50: 533-540.
55. Leonard RT, Hotchkiss CW, (1978) Plasma Membrane-associated Adenosine Triphosphatase Activity of Isolated Cortex and Stele from Corn Roots. Plant Physiol 61: 175-179.
56. Oeckler RA, Hubmayr RD, (2007) Alveolar microstrain and the dark side of the lung. Crit Care 11: 177.
57. Tschumperlin DJ, Margulies SS, (1999) Alveolar epithelial surface area-volume relationship in isolated rat lungs. J Appl Physiol 86: 2026-2033.
58. Chang SJ, Tzeng CR, Lee YH, Tai CJ, (2008) Extracellular ATP activates the PLC/PKC/ERK signaling pathway through the P2Y2 purinergic receptor leading to the induction of early growth response 1 expression and the inhibition of viability in human endometrial stromal cells. Cell Signal 20: 1248-1255.
59. Takai Y, Sasaki T, Matozaki T, (2001) Small GTP-binding proteins. Physiol Rev 81: 153-208.
60. Okada SF, Nicholas RA, Kreda SM, Lazarowski ER, Boucher RC, (2006) Physiological regulation of ATP release at the apical surface of human airway epithelia. J Biol Chem 281: 22992-23002.
61. Skaper SD, Debetto P, Giusti P, (2010) The P2X7 purinergic receptor: from physiology to neurological disorders. Faseb J 24: 337-345.
62. Weisman GA, Wang M, Kong Q, Chorna NE, Neary JT, et al. (2005) Molecular determinants of P2Y2 nucleotide receptor function: implications for proliferative and inflammatory pathways in astrocytes. Mol Neurobiol 31: 169-183.
63. Baker OJ, Camden JM, Rome DE, Seye CI, Weisman GA, (2008) P2Y2 nucleotide receptor activation up-regulates vascular cell adhesion molecule-1 [corrected] expression and enhances lymphocyte adherence to a human submandibular gland cell line. Mol Immunol 45: 65-75.
64. Boitano S, Safdar Z, Welsh DG, Bhattacharya J, Koval M, (2004) Cell-cell interactions in regulating lung function. Am J Physiol Lung Cell Mol Physiol 287: L455-459.
65. Matsuyama H, Amaya F, Hashimoto S, Ueno H, Beppu S, et al. (2008) Acute lung inflammation and ventilator-induced lung injury caused by ATP via the P2Y receptors: an experimental study. Respir Res 9: 79.
66. Kolosova IA, Mirzapoiazova T, Moreno-Vinasco L, Sammani S, Garcia JG, et al. (2008) Protective effect of purinergic agonist ATPgammaS against acute lung injury. Am J Physiol Lung Cell Mol Physiol 294: L319-324.
67. Wang S, Hubmayr RD, (2011) Type I Alveolar Epithelial Phenotype in Primary Culture. Am J Respir Cell Mol Biol.
68. Stroetz RW, Vlahakis NE, Walters BJ, Schroeder MA, Hubmayr RD, (2001) Validation of a new live cell strain system: characterization of plasma membrane stress failure. J Appl Physiol 90: 2361-2370.
69. Belete HA, Godin LM, Stroetz RW, Hubmayr RD, (2010) Experimental models to study cell wounding and repair. Cell Physiol Biochem 25: 71-80.
70. Green AS, (2004) Modelling of peak-flow wall shear stress in major airways of the lung. J Biomech 37: 661-667.