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Volumn 771, Issue , 2013, Pages 252-271

Viral infections and diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BOVINE VIRAL DIARRHEA MUCOSAL DISEASE VIRUS; CELL DAMAGE; CELL DEATH; COXSACKIE VIRUS A; COXSACKIE VIRUS B; CYTOMEGALOVIRUS; DIABETOGENESIS; ENCEPHALOMYOCARDITIS VIRUS; ENVIRONMENTAL FACTOR; FOOT AND MOUTH DISEASE VIRUS; HEREDITY; HUMAN; HUMAN PARVOVIRUS B19; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; KILHAM RAT VIRUS; LJUNGAN VIRUS; MENGO VIRUS; MUMPS VIRUS; NONHUMAN; PANCREAS ISLET BETA CELL; PARECHOVIRUS; PARVOVIRUS; REOVIRUS; RETROVIRUS; ROTAVIRUS; RUBELLA VIRUS; TOGAVIRUS; VIRUS INFECTION; ANIMAL; GENETIC PREDISPOSITION; GENETICS; REVIEW; RISK FACTOR; VIROLOGY;

EID: 84907810119     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-1-4614-5441-0_20     Document Type: Article
Times cited : (29)

References (100)
  • 1
    • 79951983776 scopus 로고    scopus 로고
    • Enterovirus infection and type 1 diabetes mellitus: Systematic review and meta-analysis of observational molecular studies
    • Yeung WC, Rawlinson WD, Craig ME. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ 2011; 342:d35.
    • (2011) BMJ , vol.342 , pp. d35
    • Yeung, W.C.1    Rawlinson, W.D.2    Craig, M.E.3
  • 2
    • 0036266382 scopus 로고    scopus 로고
    • Enterovirus RNA is found in peripheral blood mononuclear cells in a majority of type 1 diabetic children at onset
    • Yin H, Berg AK, Tuvemo T et al. Enterovirus RNA is found in peripheral blood mononuclear cells in a majority of type 1 diabetic children at onset. Diabetes 2002; 51:1964-1971.
    • (2002) Diabetes , vol.51 , pp. 1964-1971
    • Yin, H.1    Berg, A.K.2    Tuvemo, T.3
  • 3
    • 36849012027 scopus 로고    scopus 로고
    • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
    • Nejentsev S, Howson JM, Walker NM et al. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 2007; 450:887-892.
    • (2007) Nature , vol.450 , pp. 887-892
    • Nejentsev, S.1    Howson, J.M.2    Walker, N.M.3
  • 4
    • 18244421874 scopus 로고    scopus 로고
    • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR IDDM2 susceptibility locus for type 1 diabetes
    • Pugliese A, Zeller M, Fernandez A Jr et al. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR IDDM2 susceptibility locus for type 1 diabetes. Nat Genet 1997; 15:293-297.
    • (1997) Nat Genet , vol.15 , pp. 293-297
    • Pugliese, A.1    Zeller, M.2    Fernandez, A.3
  • 6
    • 10344224011 scopus 로고    scopus 로고
    • Association of the cytotoxic T-lymphocyte-associated antigen 4 gene with type 1 diabetes: Evidence for independent effects of two polymorphisms on the same haplotype block
    • Anjos SM, Tessier MC, Polychronakos C. Association of the cytotoxic T-lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block. J Clin Endocrinol Metab 2004; 89:6257-6265.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6257-6265
    • Anjos, S.M.1    Tessier, M.C.2    Polychronakos, C.3
  • 7
    • 65249131713 scopus 로고    scopus 로고
    • Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
    • Nejentsev S, Walker N, Riches D et al. Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 2009; 324:387-389.
    • (2009) Science , vol.324 , pp. 387-389
    • Nejentsev, S.1    Walker, N.2    Riches, D.3
  • 8
    • 17844387429 scopus 로고    scopus 로고
    • OAS1 splice site polymorphism controlling antiviral enzyme activity influences susceptibility to type 1 diabetes
    • Field LL, Bonnevie-Nielsen V, Pociot F et al. OAS1 splice site polymorphism controlling antiviral enzyme activity influences susceptibility to type 1 diabetes. Diabetes 2005; 54:1588-1591.
    • (2005) Diabetes , vol.54 , pp. 1588-1591
    • Field, L.L.1    Bonnevie-Nielsen, V.2    Pociot, F.3
  • 9
    • 33745297838 scopus 로고    scopus 로고
    • Decreased in vitro type 1 immune response against coxsackie virus B4 in children with type 1 diabetes
    • Skarsvik S, Puranen J, Honkanen J et al. Decreased in vitro type 1 immune response against coxsackie virus B4 in children with type 1 diabetes. Diabetes 2006; 55:996-1003.
    • (2006) Diabetes , vol.55 , pp. 996-1003
    • Skarsvik, S.1    Puranen, J.2    Honkanen, J.3
  • 10
    • 34247627376 scopus 로고    scopus 로고
    • Coxsackie B4 virus infection of |3 cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
    • Dotta F, Censini S, Van Halteren AG et al. Coxsackie B4 virus infection of |3 cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci USA 2007; 104:5115-5120.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5115-5120
    • Dotta, F.1    Censini, S.2    Van Halteren, A.G.3
  • 11
    • 0033755202 scopus 로고    scopus 로고
    • Virus-induced autoimmune diabetes: Most beta cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes
    • Seewaldt S, Thomas HE, Ejrnaes M et al. Virus-induced autoimmune diabetes: most beta cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes. Diabetes 2000;49:1801-1809.
    • (2000) Diabetes , vol.49 , pp. 1801-1809
    • Seewaldt, S.1    Thomas, H.E.2    Ejrnaes, M.3
  • 12
    • 20044385554 scopus 로고    scopus 로고
    • Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
    • Lang KS, Recher M, Junt T et al. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med 2005; 11:138-145.
    • (2005) Nat Med , vol.11 , pp. 138-145
    • Lang, K.S.1    Recher, M.2    Junt, T.3
  • 13
    • 0037217057 scopus 로고    scopus 로고
    • A new look at viruses in type 1 diabetes
    • Jun HS, Yoon JW. A new look at viruses in type 1 diabetes. Diabetes Metab Res Rev 2003; 19:8-31.
    • (2003) Diabetes Metab Res Rev , vol.19 , pp. 8-31
    • Jun, H.S.1    Yoon, J.W.2
  • 14
    • 0034979274 scopus 로고    scopus 로고
    • Requirements for viral-mediated autoimmune diabetes: Beta-cell damage and immune infiltration
    • Horwitz MS, Fine C, Ilic A et al. Requirements for viral-mediated autoimmune diabetes: beta-cell damage and immune infiltration. J Autoimmun 2001; 16:211-217.
    • (2001) J Autoimmun , vol.16 , pp. 211-217
    • Horwitz, M.S.1    Fine, C.2    Ilic, A.3
  • 15
    • 0036141519 scopus 로고    scopus 로고
    • Presented antigen from damaged pancreatic beta cells activates autoreactive T-cells in virus-mediated autoimmune diabetes
    • Horwitz MS, Ilic A, Fine C et al. Presented antigen from damaged pancreatic beta cells activates autoreactive T-cells in virus-mediated autoimmune diabetes. J Clin Invest 2002; 109:79-87.
    • (2002) J Clin Invest , vol.109 , pp. 79-87
    • Horwitz, M.S.1    Ilic, A.2    Fine, C.3
  • 16
    • 0028007192 scopus 로고
    • Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes
    • Atkinson MA, Bowman MA, Campbell L et al. Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes. J Clin Invest 1994; 94:2125-2129.
    • (1994) J Clin Invest , vol.94 , pp. 2125-2129
    • Atkinson, M.A.1    Bowman, M.A.2    Campbell, L.3
  • 17
    • 0028143519 scopus 로고
    • T-cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele
    • Tian J, Lehmann PV, Kaufman DL. T-cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele. JExp Med 1994; 180:1979-1984.
    • (1994) JExp Med , vol.180 , pp. 1979-1984
    • Tian, J.1    Lehmann, P.V.2    Kaufman, D.L.3
  • 18
    • 0034011436 scopus 로고    scopus 로고
    • Virus-induced diabetes in atransgenic model: Role of cross-reacting viruses and quantitation of effector T-cells needed to cause disease
    • Sevilla N, Homann D, Von Herrath M et al. Virus-induced diabetes in atransgenic model: role of cross-reacting viruses and quantitation of effector T-cells needed to cause disease. J Virol 2000; 74:3284-3292.
    • (2000) J Virol , vol.74 , pp. 3284-3292
    • Sevilla, N.1    Homann, D.2    Von Herrath, M.3
  • 19
    • 15244341417 scopus 로고    scopus 로고
    • A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes
    • Christen U, Edelmann KH, McGavern DB et al. A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes. J Clin Invest 2004; 114:1290-1298.
    • (2004) J Clin Invest , vol.114 , pp. 1290-1298
    • Christen, U.1    Edelmann, K.H.2    McGavern, D.B.3
  • 20
    • 79251640900 scopus 로고    scopus 로고
    • Innate immunity and the pathogenesis of type 1 diabetes
    • Grieco FA, Vendrame F, Spagnuolo I et al. Innate immunity and the pathogenesis of type 1 diabetes. Semin Immunopathol 2011; 33:57-66.
    • (2011) Semin Immunopathol , vol.33 , pp. 57-66
    • Grieco, F.A.1    Vendrame, F.2    Spagnuolo, I.3
  • 21
    • 0033168630 scopus 로고    scopus 로고
    • Polyriboinosinic polyribocytidylic acid (poly (I:C)) induces stable maturation of functionally active human dendritic cells
    • Verdijk RM, Mutis T, Esendam B et al. Polyriboinosinic polyribocytidylic acid (poly (I:C)) induces stable maturation of functionally active human dendritic cells. J Immunol 1999; 163:57-61.
    • (1999) J Immunol , vol.163 , pp. 57-61
    • Verdijk, R.M.1    Mutis, T.2    Esendam, B.3
  • 22
    • 0035423390 scopus 로고    scopus 로고
    • IL-15 is expressed by dendritic cells in response to type IIFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation
    • Mattei F, Schiavoni G, Belardelli F et al. IL-15 is expressed by dendritic cells in response to type IIFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation. J Immunol 2001; 167:1179-1187.
    • (2001) J Immunol , vol.167 , pp. 1179-1187
    • Mattei, F.1    Schiavoni, G.2    Belardelli, F.3
  • 23
    • 0036214325 scopus 로고    scopus 로고
    • Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: Potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus
    • Liu D, Cardozo AK, Darville MI et al. Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus. Endocrinology 2002; 143:1225-1234.
    • (2002) Endocrinology , vol.143 , pp. 1225-1234
    • Liu, D.1    Cardozo, A.K.2    Darville, M.I.3
  • 24
    • 0035140170 scopus 로고    scopus 로고
    • Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets
    • Blair LA, Heitmeier MR, Scarim AL et al. Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets. Diabetes 2001; 50:283-290.
    • (2001) Diabetes , vol.50 , pp. 283-290
    • Blair, L.A.1    Heitmeier, M.R.2    Scarim, A.L.3
  • 25
    • 0031723365 scopus 로고    scopus 로고
    • Low dose poly I:C prevents diabetes in the diabetes prone BB rat
    • Sobel DO, Goyal D, Ahvazi B et al. Low dose poly I:C prevents diabetes in the diabetes prone BB rat. J Autoimmun 1998; 11:343-352.
    • (1998) J Autoimmun , vol.11 , pp. 343-352
    • Sobel, D.O.1    Goyal, D.2    Ahvazi, B.3
  • 26
    • 33846934465 scopus 로고    scopus 로고
    • NK3-like NK cells are involved in protective effect of polyinosinic-polycytidylic acid on type 1 diabetes in nonobese diabetic mice
    • Zhou R, Wei H, Tian Z. NK3-like NK cells are involved in protective effect of polyinosinic-polycytidylic acid on type 1 diabetes in nonobese diabetic mice. J Immunol 2007; 178:2141-2147.
    • (2007) J Immunol , vol.178 , pp. 2141-2147
    • Zhou, R.1    Wei, H.2    Tian, Z.3
  • 27
    • 70350596084 scopus 로고    scopus 로고
    • Coxsackievirus B4 and type 1 diabetes pathogenesis: Contribution of animal models
    • Jaïdane H, Sane F, Gharbi J et al. Coxsackievirus B4 and type 1 diabetes pathogenesis: contribution of animal models. Diabetes Metab Res Rev 2009; 25:591-603.
    • (2009) Diabetes Metab Res Rev , vol.25 , pp. 591-603
    • Jaïdane, H.1    Sane, F.2    Gharbi, J.3
  • 28
    • 77951666052 scopus 로고    scopus 로고
    • Pathogenesis of type 1 diabetes mellitus: Interplay between enterovirus and host
    • Hober D, Sauter P. Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host. Nat Rev Endocrinol 2010; 6:279-289.
    • (2010) Nat Rev Endocrinol , vol.6 , pp. 279-289
    • Hober, D.1    Sauter, P.2
  • 29
    • 73349083391 scopus 로고    scopus 로고
    • Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats
    • Holmberg R, Klitz W, Blixt M et al. Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats. Microbiol Immunol 2009; 53:567-572.
    • (2009) Microbiol Immunol , vol.53 , pp. 567-572
    • Holmberg, R.1    Klitz, W.2    Blixt, M.3
  • 30
    • 79251473394 scopus 로고    scopus 로고
    • Longitudinal study of Parechovirus infection in infancy and risk of repeated positivity for multiple islet autoantibodies: The MIDIA Study
    • Tapia G, Cinek O, Rasmussen T et al. Longitudinal study of Parechovirus infection in infancy and risk of repeated positivity for multiple islet autoantibodies: the MIDIA Study. Pediatr Diabetes 2011; 12:58-62.
    • (2011) Pediatr Diabetes , vol.12 , pp. 58-62
    • Tapia, G.1    Cinek, O.2    Rasmussen, T.3
  • 31
    • 33947330461 scopus 로고    scopus 로고
    • Viral infections as potential triggers of type 1 diabetes
    • Van der Werf N, Kroese FG, Rozing J et al. Viral infections as potential triggers of type 1 diabetes. Diabetes Metab Res Rev 2007; 23:169-183.
    • (2007) Diabetes Metab Res Rev , vol.23 , pp. 169-183
    • Van Der-Werf, N.1    Kroese, F.G.2    Rozing, J.3
  • 32
  • 33
    • 0023838175 scopus 로고
    • Molecular mimicry between insulin and retroviral antigen p73. Development of cross-reactive autoantibodies in sera of NOD and C57BL/KsJ db/db mice
    • Serreze DV, Leiter EH, Kuff EL et al. Molecular mimicry between insulin and retroviral antigen p73. Development of cross-reactive autoantibodies in sera of NOD and C57BL/KsJ db/db mice. Diabetes 1988;37:351-358.
    • (1988) Diabetes , vol.37 , pp. 351-358
    • Serreze, D.V.1    Leiter, E.H.2    Kuff, E.L.3
  • 34
    • 0030840944 scopus 로고    scopus 로고
    • A human endogenous retroviral superantigenas candidate autoimmune gene in type 1 diabetes
    • Conrad B, Weissmahr RN, Boni J et al. A human endogenous retroviral superantigenas candidate autoimmune gene in type 1 diabetes. Cell 1997; 90:303-313.
    • (1997) Cell , vol.90 , pp. 303-313
    • Conrad, B.1    Weissmahr, R.N.2    Boni, J.3
  • 35
    • 33644759308 scopus 로고    scopus 로고
    • Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice
    • Wetzel JD, Barton ES, Chappell JD et al. Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice. J Virol 2006; 80:3078-3082.
    • (2006) J Virol , vol.80 , pp. 3078-3082
    • Wetzel, J.D.1    Barton, E.S.2    Chappell, J.D.3
  • 36
    • 34249940915 scopus 로고    scopus 로고
    • Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset
    • Graham KL, O'Donnell J A, Tan Y et al. Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset. J Virol 2007; 81:6446-6458.
    • (2007) J Virol , vol.81 , pp. 6446-6458
    • Graham, K.L.1    O'Donnell, J.A.2    Tan, Y.3
  • 37
    • 45749153017 scopus 로고    scopus 로고
    • Rotavirus infection accelerates type 1 diabetes in mice with established insulitis
    • Graham KL, Sanders N, Tan Y et al. Rotavirus infection accelerates type 1 diabetes in mice with established insulitis. J Virol 2008; 82:6139-6149.
    • (2008) J Virol , vol.82 , pp. 6139-6149
    • Graham, K.L.1    Sanders, N.2    Tan, Y.3
  • 38
    • 0036720415 scopus 로고    scopus 로고
    • Growth of rotaviruses in primary pancreatic cells
    • Coulson BS, Witterick PD, Tan Y et al. Growth of rotaviruses in primary pancreatic cells. J Virol 2002; 76:9537-9544.
    • (2002) J Virol , vol.76 , pp. 9537-9544
    • Coulson, B.S.1    Witterick, P.D.2    Tan, Y.3
  • 39
    • 0033853920 scopus 로고    scopus 로고
    • Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes
    • Honeyman MC, Coulson BS, Stone NJ. Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes. Diabetes 2000; 49:1319-1323.
    • (2000) Diabetes , vol.49 , pp. 1319-1323
    • Honeyman, M.C.1    Coulson, B.S.2    Stone, N.J.3
  • 40
    • 23944456826 scopus 로고    scopus 로고
    • Rheumatoid arthritis, type 1 diabetes, and Graves' disease after acute parvovirus bl9 infection
    • Munakata Y, Kodera T, Saito T et al. Rheumatoid arthritis, type 1 diabetes, and Graves' disease after acute parvovirus bl9 infection. Lancet 2005; 366:780.
    • (2005) Lancet , vol.366 , pp. 780
    • Munakata, Y.1    Kodera, T.2    Saito, T.3
  • 41
    • 77449125677 scopus 로고    scopus 로고
    • Infection with viruses from several families triggers autoimmune diabetes in L.E.W.∗1WR1 rats: Prevention of diabetes by maternal immunization
    • Tirabassi RS, Guberski DL, Blankenhorn EP et al. Infection with viruses from several families triggers autoimmune diabetes in L.E.W.∗1WR1 rats: prevention of diabetes by maternal immunization. Diabetes 2010; 59:110-118.
    • (2010) Diabetes , vol.59 , pp. 110-118
    • Tirabassi, R.S.1    Guberski, D.L.2    Blankenhorn, E.P.3
  • 42
    • 0023850748 scopus 로고
    • Prevention of type I diabetes in nonobese diabetic mice by virus infection
    • Oldstone MB. Prevention of type I diabetes in nonobese diabetic mice by virus infection. Science 1988; 239:500-502.
    • (1988) Science , vol.239 , pp. 500-502
    • Oldstone, M.B.1
  • 43
    • 77956262741 scopus 로고    scopus 로고
    • Virus infections and type 1 diabetes risk
    • Roivainen M, Klingel K. Virus infections and type 1 diabetes risk. Curr Diab Rep 2010; 10:350-356.
    • (2010) Curr Diab Rep , vol.10 , pp. 350-356
    • Roivainen, M.1    Klingel, K.2
  • 44
    • 0019521358 scopus 로고
    • Primary structure, gene organization and polypeptide expression of poliovirus RNA
    • Kitamura N, Semler BL, Rothberg PG et al. Primary structure, gene organization and polypeptide expression of poliovirus RNA. Nature 1981; 291:547-553.
    • (1981) Nature , vol.291 , pp. 547-553
    • Kitamura, N.1    Semler, B.L.2    Rothberg, P.G.3
  • 45
  • 46
    • 57149101123 scopus 로고    scopus 로고
    • Role of coxsackievirus B4 in the pathogenesis of type 1 diabetes
    • Jaïdane H, Hober D. Role of coxsackievirus B4 in the pathogenesis of type 1 diabetes. Diabetes Metab 2008; 34:537-548.
    • (2008) Diabetes Metab , vol.34 , pp. 537-548
    • Jaïdane, H.1    Hober, D.2
  • 47
    • 0017169540 scopus 로고
    • Susceptibility of mice to group B coxsackie virus is influenced by the diabetic gene
    • Webb SR, Loria RM, Madge GE et al. Susceptibility of mice to group B coxsackie virus is influenced by the diabetic gene. J Exp Med 1976; 143:1239-1248.
    • (1976) J Exp Med , vol.143 , pp. 1239-1248
    • Webb, S.R.1    Loria, R.M.2    Madge, G.E.3
  • 48
    • 0021265186 scopus 로고
    • Influence of diabetes mellitus heredity on susceptibility to coxsackievirus B4
    • Loria RM, Montgomery LB, Corey LA et al. Influence of diabetes mellitus heredity on susceptibility to coxsackievirus B4. Arch Virol 1984; 81:251-262.
    • (1984) Arch Virol , vol.81 , pp. 251-262
    • Loria, R.M.1    Montgomery, L.B.2    Corey, L.A.3
  • 49
    • 0022859347 scopus 로고
    • Genetic predisposition to diabetes mellitus is associated with impaired humoral immunity to coxsackievirus B4
    • Loria RM, Montgomery LB, Tuttle-Fuller N et al. Genetic predisposition to diabetes mellitus is associated with impaired humoral immunity to coxsackievirus B4. Diabetes Res Clin Pract 1986; 2:91-96.
    • (1986) Diabetes Res Clin Pract , vol.2 , pp. 91-96
    • Loria, R.M.1    Montgomery, L.B.2    Tuttle-Fuller, N.3
  • 50
    • 0022559159 scopus 로고
    • Coxsackie virus B4 produces transient diabetes in nonhuman primates
    • Yoon JW, London WT, Curfman BL et al. Coxsackie virus B4 produces transient diabetes in nonhuman primates. Diabetes 1986; 35:712-716.
    • (1986) Diabetes , vol.35 , pp. 712-716
    • Yoon, J.W.1    London, W.T.2    Curfman, B.L.3
  • 51
    • 33846785541 scopus 로고    scopus 로고
    • Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes
    • Elshebani A, Olsson A, Westman J et al. Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes. Virus Res 2007; 124:193-203.
    • (2007) Virus Res , vol.124 , pp. 193-203
    • Elshebani, A.1    Olsson, A.2    Westman, J.3
  • 52
    • 0042266289 scopus 로고    scopus 로고
    • Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells
    • Flodstrom M, Tsai D, Fine C et al. Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells. Diabetes 2003; 52:2025-2034.
    • (2003) Diabetes , vol.52 , pp. 2025-2034
    • Flodstrom, M.1    Tsai, D.2    Fine, C.3
  • 53
    • 0036158287 scopus 로고    scopus 로고
    • Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR
    • Härkönen T, Lankinen H, Davydova B et al. Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR. J Med Virol 2002; 66:340-350.
    • (2002) J Med Virol , vol.66 , pp. 340-350
    • Härkönen, T.1    Lankinen, H.2    Davydova, B.3
  • 54
    • 31544479100 scopus 로고    scopus 로고
    • Molecular mimicry, bystander activation, or viral persistence: Infections and autoimmune disease
    • Fujinami RS, von Herrath MG, Christen U et al. Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease. Clin Microbiol Rev 2006; 19:80-94.
    • (2006) Clin Microbiol Rev , vol.19 , pp. 80-94
    • Fujinami, R.S.1    Von Herrath, M.G.2    Christen, U.3
  • 55
    • 9144226256 scopus 로고    scopus 로고
    • TCR affinity and negative regulation limit autoimmunity
    • Gronski MA, Boulter JM, Moskophidis D et al. TCR affinity and negative regulation limit autoimmunity. Nat Med 2004; 10:1234-1239.
    • (2004) Nat Med , vol.10 , pp. 1234-1239
    • Gronski, M.A.1    Boulter, J.M.2    Moskophidis, D.3
  • 56
    • 0031874342 scopus 로고    scopus 로고
    • Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry
    • Horwitz MS, Bradley LM, Harbertson J et al. Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry. Nat Med 1998; 4:781-785.
    • (1998) Nat Med , vol.4 , pp. 781-785
    • Horwitz, M.S.1    Bradley, L.M.2    Harbertson, J.3
  • 57
    • 0034083713 scopus 로고    scopus 로고
    • Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets
    • Serreze DV, Ottendorfer EW, Ellis TM et al. Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets. Diabetes 2000; 49:708-711.
    • (2000) Diabetes , vol.49 , pp. 708-711
    • Serreze, D.V.1    Ottendorfer, E.W.2    Ellis, T.M.3
  • 58
    • 7044254968 scopus 로고    scopus 로고
    • Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: Insulitis determines susceptibility of pancreatic islets to virus infection
    • Drescher KM, Kono K, Bopegamage S et al. Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection. Virology 2004; 329:381-394.
    • (2004) Virology , vol.329 , pp. 381-394
    • Drescher, K.M.1    Kono, K.2    Bopegamage, S.3
  • 59
    • 0036889147 scopus 로고    scopus 로고
    • Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: Inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence
    • Tracy S, Drescher KM, Chapman NM et al. Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence. J Virol 2002; 76:12097-12111.
    • (2002) J Virol , vol.76 , pp. 12097-12111
    • Tracy, S.1    Drescher, K.M.2    Chapman, N.M.3
  • 60
    • 0033579877 scopus 로고    scopus 로고
    • The role of macrophages in T-cell-mediated autoimmune diabetes in nonobese diabetic mice
    • Jun HS, Yoon CS, Zbytnuik L et al. The role of macrophages in T-cell-mediated autoimmune diabetes in nonobese diabetic mice. J Exp Med 1999; 189:347-358.
    • (1999) J Exp Med , vol.189 , pp. 347-358
    • Jun, H.S.1    Yoon, C.S.2    Zbytnuik, L.3
  • 61
    • 1542330848 scopus 로고    scopus 로고
    • Coxsackieviral-mediated diabetes: Induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells
    • Horwitz MS, Ilic A, Fine C et al. Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells. Clin Immunol 2004; 110:134-144.
    • (2004) Clin Immunol , vol.110 , pp. 134-144
    • Horwitz, M.S.1    Ilic, A.2    Fine, C.3
  • 62
    • 19944426633 scopus 로고    scopus 로고
    • Diabetes acceleration or prevention by a coxsackievirus B4 infection: Critical requirements for both interleukin-4 and gamma interferon
    • Serreze DV, Wasserfall C, Ottendorfer EW et al. Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon. J Virol 2005; 79:1045-1052.
    • (2005) J Virol , vol.79 , pp. 1045-1052
    • Serreze, D.V.1    Wasserfall, C.2    Ottendorfer, E.W.3
  • 63
    • 79955157031 scopus 로고    scopus 로고
    • TLR2 signaling improves immunoregulation to prevent type 1 diabetes
    • Filippi CM, Ehrhardt K, Estes EA et al. TLR2 signaling improves immunoregulation to prevent type 1 diabetes. Eur J Immunol 2011; 41:1399-1409.
    • (2011) Eur J Immunol , vol.41 , pp. 1399-1409
    • Filippi, C.M.1    Ehrhardt, K.2    Estes, E.A.3
  • 64
    • 67650999438 scopus 로고    scopus 로고
    • Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice
    • Filippi CM, Estes EA, Oldham JE et al. Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice. J Clin Invest 2009; 119:1515-1523.
    • (2009) J Clin Invest , vol.119 , pp. 1515-1523
    • Filippi, C.M.1    Estes, E.A.2    Oldham, J.E.3
  • 65
    • 0345215155 scopus 로고    scopus 로고
    • Demonstration of persistent enterovirus in the pancreas of diabetic mice by in situ polymerase chain reaction
    • Berger MM, See DM, Aymard M et al. Demonstration of persistent enterovirus in the pancreas of diabetic mice by in situ polymerase chain reaction. Clin Diagn Virol 1998; 9:141-143.
    • (1998) Clin Diagn Virol , vol.9 , pp. 141-143
    • Berger, M.M.1    See, D.M.2    Aymard, M.3
  • 66
    • 0028919543 scopus 로고
    • Pathogenesis of virus-induced diabetes in mice
    • See DM, Tilles JG. Pathogenesis of virus-induced diabetes in mice. J Infect Dis 1995; 171:1131-1138.
    • (1995) J Infect Dis , vol.171 , pp. 1131-1138
    • See, D.M.1    Tilles, J.G.2
  • 67
    • 66449116276 scopus 로고    scopus 로고
    • The prevalence of enteroviral capsid protein VP-1 immunostaining in pancreatic islets in human type 1 diabetes
    • Richardson SJ, Willcox A, Bone AJ et al. The prevalence of enteroviral capsid protein VP-1 immunostaining in pancreatic islets in human type 1 diabetes. Diabetologia 2009; 52:1143-1151.
    • (2009) Diabetologia , vol.52 , pp. 1143-1151
    • Richardson, S.J.1    Willcox, A.2    Bone, A.J.3
  • 68
    • 1542345055 scopus 로고    scopus 로고
    • Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells
    • Ylipaasto P, Klingel K, Lindberg AM et al. Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells. Diabetologia 2004; 47:225-239.
    • (2004) Diabetologia , vol.47 , pp. 225-239
    • Ylipaasto, P.1    Klingel, K.2    Lindberg, A.M.3
  • 69
    • 0024558462 scopus 로고
    • In vivo infection of mice with Coxsackie B4 virus induces long-term functional changes in pancreatic islets with minimal alteration in blood glucose
    • Szopa TM, Dronfield DM, Ward T et al. In vivo infection of mice with Coxsackie B4 virus induces long-term functional changes in pancreatic islets with minimal alteration in blood glucose. Diabet Med 1989;6:314-319.
    • (1989) Diabet Med , vol.6 , pp. 314-319
    • Szopa, T.M.1    Dronfield, D.M.2    Ward, T.3
  • 70
    • 58149458888 scopus 로고    scopus 로고
    • Toll-like receptor 3 signaling on macrophages is required for survival following coxsackievirus B4 infection
    • Richer MJ, Lavallée DJ, Shanina I et al. Toll-like receptor 3 signaling on macrophages is required for survival following coxsackievirus B4 infection. PLoS One 2009; 4:e4127.
    • (2009) PLoS One , vol.4 , pp. e4127
    • Richer, M.J.1    Lavallée, D.J.2    Shanina, I.3
  • 71
    • 79953279338 scopus 로고    scopus 로고
    • The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling
    • Mukherjee A, Morosky SA, Delorme-Axford E et al. The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. PLoS Pathog 2011;7:el001311.
    • (2011) PLoS Pathog , vol.7 , pp. el001311
    • Mukherjee, A.1    Morosky, S.A.2    Delorme-Axford, E.3
  • 72
    • 0026350805 scopus 로고
    • Induction of type I diabetes by Kilham's rat virus in diabetes-resistant BB/Worrats
    • Guberski DL, Thomas VA, Shek WR et al. Induction of type I diabetes by Kilham's rat virus in diabetes-resistant BB/Worrats. Science 1991;254:1010-1013.
    • (1991) Science , vol.254 , pp. 1010-1013
    • Guberski, D.L.1    Thomas, V.A.2    Shek, W.R.3
  • 73
    • 15944378503 scopus 로고    scopus 로고
    • The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection
    • Blankenhorn EP, Rodemich L, Martin-Fernandez C et al. The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. Diabetes 2005;54:1233-1237
    • (2005) Diabetes , vol.54 , pp. 1233-1237
    • Blankenhorn, E.P.1    Rodemich, L.2    Martin-Fernandez, C.3
  • 74
    • 0027165465 scopus 로고
    • Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor rats
    • Brown DW, Welsh RM, Like AA. Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor rats. J Virol 1993; 67:5873-5878.
    • (1993) J Virol , vol.67 , pp. 5873-5878
    • Brown, D.W.1    Welsh, R.M.2    Like, A.A.3
  • 75
    • 0034284233 scopus 로고    scopus 로고
    • Cellular and molecular mechanism for Kilham rat virus-induced autoimmune diabetes in DR-BB rats
    • Chung YH, Jun HS, Son M et al. Cellular and molecular mechanism for Kilham rat virus-induced autoimmune diabetes in DR-BB rats. J Immunol 2000; 165:2866-2876.
    • (2000) J Immunol , vol.165 , pp. 2866-2876
    • Chung, Y.H.1    Jun, H.S.2    Son, M.3
  • 76
    • 0346665756 scopus 로고    scopus 로고
    • Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T-cell populations
    • Zipris D, Hillebrands JH, Welsh RM et al. Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T-cell populations. J Immunol 2003; 170:3592-3602.
    • (2003) J Immunol , vol.170 , pp. 3592-3602
    • Zipris, D.1    Hillebrands, J.H.2    Welsh, R.M.3
  • 77
    • 3142659582 scopus 로고    scopus 로고
    • Immunoregulatory role of nitric oxide in Kilham rat virus-induced autoimmune diabetes in DR-BB rats
    • Mendez II, Chung YH, Jun HS et al. Immunoregulatory role of nitric oxide in Kilham rat virus-induced autoimmune diabetes in DR-BB rats. J Immunol 2004; 173:1327-1335.
    • (2004) J Immunol , vol.173 , pp. 1327-1335
    • Mendez, I.I.1    Chung, Y.H.2    Jun, H.S.3
  • 78
    • 10844295809 scopus 로고    scopus 로고
    • TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats
    • Zipris D, Lien E, Xie JX et al. TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. J Immunol 2005; 174:131-142.
    • (2005) J Immunol , vol.174 , pp. 131-142
    • Zipris, D.1    Lien, E.2    Xie, J.X.3
  • 79
    • 33846190681 scopus 로고    scopus 로고
    • TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat
    • Zipris D, Lien E, Nair A et al. TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat. J Immunol 2007; 178:693-701.
    • (2007) J Immunol , vol.178 , pp. 693-701
    • Zipris, D.1    Lien, E.2    Nair, A.3
  • 80
    • 67349212253 scopus 로고    scopus 로고
    • DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes
    • Wolter TR, Wong R, Sarkar SA et al. DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes. Clin Immunol 2009; 132:103-115.
    • (2009) Clin Immunol , vol.132 , pp. 103-115
    • Wolter, T.R.1    Wong, R.2    Sarkar, S.A.3
  • 81
    • 0346502842 scopus 로고    scopus 로고
    • Role of peritoneal macrophages in cytomegalovirus-induced acceleration of autoimmune diabetes in BB-rats
    • Hillebrands JL, van der Werf N, Klatter FA et al. Role of peritoneal macrophages in cytomegalovirus-induced acceleration of autoimmune diabetes in BB-rats. Clin Dev Immunol 2003; 10:133-139.
    • (2003) Clin Dev Immunol , vol.10 , pp. 133-139
    • Hillebrands, J.L.1    Van Der-Werf, N.2    Klatter, F.A.3
  • 82
    • 0029760157 scopus 로고    scopus 로고
    • The BB/Wor rat and the balance hypothesis of autoimmunity
    • Mordes JP, Bortell R, Doukas J et al. The BB/Wor rat and the balance hypothesis of autoimmunity. Diabetes Metab Rev 1996; 12:103-109.
    • (1996) Diabetes Metab Rev , vol.12 , pp. 103-109
    • Mordes, J.P.1    Bortell, R.2    Doukas, J.3
  • 83
    • 24144449831 scopus 로고    scopus 로고
    • LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation
    • Mordes JP, Guberski DL, Leif JH et al. LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation. Diabetes 2005; 54:2727-2733.
    • (2005) Diabetes , vol.54 , pp. 2727-2733
    • Mordes, J.P.1    Guberski, D.L.2    Leif, J.H.3
  • 84
    • 0038222568 scopus 로고    scopus 로고
    • Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes-indication of an increased environmental pressure?
    • Hermann R, Knip M, Veijola R et al. Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes-indication of an increased environmental pressure? Diabetologia2003; 46:420-425.
    • (2003) Diabetologia , vol.46 , pp. 420-425
    • Hermann, R.1    Knip, M.2    Veijola, R.3
  • 85
    • 49649104814 scopus 로고    scopus 로고
    • The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes
    • Fourlanos S, Varney MD, Tait BD et al. The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes. Diabetes Care 2003; 31:1546-1549.
    • (2003) Diabetes Care , vol.31 , pp. 1546-1549
    • Fourlanos, S.1    Varney, M.D.2    Tait, B.D.3
  • 86
    • 33746548378 scopus 로고    scopus 로고
    • Incidence and trends of childhood Type 1 diabetes worldwide 1990-1999
    • DIAMOND Project Group, Incidence and trends of childhood Type 1 diabetes worldwide 1990-1999. Diabet Med 2006;23:857-866.
    • (2006) Diabet Med , vol.23 , pp. 857-866
  • 87
    • 0041324953 scopus 로고
    • Humoral beta cell autoimmunity is rare in patients with congenital rubella
    • Viskari H, Paronen J, Keskinen P. Humoral beta cell autoimmunity is rare in patients with congenital rubella. Clin Exp Immunol 1978; 133:378-383.
    • (1978) Clin Exp Immunol , vol.133 , pp. 378-383
    • Viskari, H.1    Paronen, J.2    Keskinen, P.3
  • 88
    • 0014673558 scopus 로고
    • Viral Antibodies in diabetes mellitus
    • Gamble DR, Kinsley MJ, Fitzgerald MG et al. Viral Antibodies in diabetes mellitus. BMJ 1969; 3:627-630.
    • (1969) BMJ , vol.3 , pp. 627-630
    • Gamble, D.R.1    Kinsley, M.J.2    Fitzgerald, M.G.3
  • 89
    • 0033624114 scopus 로고    scopus 로고
    • Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: The Finnish diabetes prediction and prevention study
    • Lönnrot M, Korpela K, Knip M et al. Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: the Finnish Diabetes Prediction and Prevention Study. Diabetes 2000;49:1314-1318.
    • (2000) Diabetes , vol.49 , pp. 1314-1318
    • Lönnrot, M.1    Korpela, K.2    Knip, M.3
  • 90
    • 0034120066 scopus 로고    scopus 로고
    • Increased level of interferon-alpha in blood of patients with insulin-dependent diabetes mellitus: Relationship with coxsackievirus B infection
    • Chehadeh W, Weill J, Vantyghem MC et al. Increased level of interferon-alpha in blood of patients with insulin-dependent diabetes mellitus: relationship with coxsackievirus B infection. J Infect Dis 2000; 181:1929-1939.
    • (2000) J Infect Dis , vol.181 , pp. 1929-1939
    • Chehadeh, W.1    Weill, J.2    Vantyghem, M.C.3
  • 91
    • 0033779186 scopus 로고    scopus 로고
    • Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells
    • Chehadeh W, Kerr-Conte J, Pattou F et al. Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells. J Virol 2000; 74:10153-10164.
    • (2000) J Virol , vol.74 , pp. 10153-10164
    • Chehadeh, W.1    Kerr-Conte, J.2    Pattou, F.3
  • 92
    • 0018799757 scopus 로고
    • Isolation of a virus from the pancreas of a child with diabetic ketoacidosis
    • Yoon JW, Austin M, Onodera T et al. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N Engl J Med 1979; 300:1173-1179.
    • (1979) N Engl J Med , vol.300 , pp. 1173-1179
    • Yoon, J.W.1    Austin, M.2    Onodera, T.3
  • 93
    • 0035668779 scopus 로고    scopus 로고
    • A choice of death- The signal transduction of immune mediated beta-cell apoptosis
    • Eizirik DL, Mandrup-Poulsen T. A choice of death- the signal transduction of immune mediated beta-cell apoptosis. Diabetologia 2001; 44:2115-2133.
    • (2001) Diabetologia , vol.44 , pp. 2115-2133
    • Eizirik, D.L.1    Mandrup-Poulsen, T.2
  • 94
    • 23844550325 scopus 로고    scopus 로고
    • Global profiling of coxsakievirus- and cytokine-induced gene expression in human pancreatic islets
    • Ylipaasto P, Kutlu B, Rasilainen S et al. Global profiling of coxsakievirus- and cytokine-induced gene expression in human pancreatic islets. Diabetologia 2005; 48:1510-1522.
    • (2005) Diabetologia , vol.48 , pp. 1510-1522
    • Ylipaasto, P.1    Kutlu, B.2    Rasilainen, S.3
  • 95
    • 77956564688 scopus 로고    scopus 로고
    • Enterovirus markers and serum CXCL10 in children with type 1 diabetes
    • Berg AK, Tuvemo T, Frisk G. Enterovirus markers and serum CXCL10 in children with type 1 diabetes. J Med Virol 2010; 82:1594-1599.
    • (2010) J Med Virol , vol.82 , pp. 1594-1599
    • Berg, A.K.1    Tuvemo, T.2    Frisk, G.3
  • 96
    • 0031883094 scopus 로고    scopus 로고
    • Molecular mimicry in diabetes mellitus: The homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses andbinds to the diabetes associated HLA-DR3 molecule
    • Vreugdenhil GR, Geluk A, Ottenhoff TH et al. Molecular mimicry in diabetes mellitus: the homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses andbinds to the diabetes associated HLA-DR3 molecule. Diabetologia 1998; 41:40-46.
    • (1998) Diabetologia , vol.41 , pp. 40-46
    • Vreugdenhil, G.R.1    Geluk, A.2    Ottenhoff, T.H.3
  • 97
    • 0036158287 scopus 로고    scopus 로고
    • Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR
    • Härkönen T, Lankinen H, Davydova B et al. Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR. J Med Virol 2002; 66:340-350.
    • (2002) J Med Virol , vol.66 , pp. 340-350
    • Härkönen, T.1    Lankinen, H.2    Davydova, B.3
  • 98
    • 77949889458 scopus 로고    scopus 로고
    • Evidence for molecular mimicry between human T-cell epitopes in rotavirus and pancreatic islet autoantigens
    • Honeyman MC, Stone NL, Falk BA et al. Evidence for molecular mimicry between human T-cell epitopes in rotavirus and pancreatic islet autoantigens. J Immunol 2010; 184:2204-2210.
    • (2010) J Immunol , vol.184 , pp. 2204-2210
    • Honeyman, M.C.1    Stone, N.L.2    Falk, B.A.3
  • 99
    • 54549122338 scopus 로고    scopus 로고
    • Innate immunity and intestinal microbiota in the development of Type 1 diabetes
    • Wen L, Ley RE, Volchkov PV et al. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 2008; 455:1109-1113.
    • (2008) Nature , vol.455 , pp. 1109-1113
    • Wen, L.1    Ley, R.E.2    Volchkov, P.V.3
  • 100
    • 23844493809 scopus 로고    scopus 로고
    • Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse
    • Calcinaro F, Dionisi S, Marinaro M et al. Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse. Diabetologia 2005; 48:1565-1575.
    • (2005) Diabetologia , vol.48 , pp. 1565-1575
    • Calcinaro, F.1    Dionisi, S.2    Marinaro, M.3


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