메뉴 건너뛰기




Volumn 74, Issue 7, 2000, Pages 3284-3292

Virus-induced diabetes in a transgenic model: Role of cross-reacting viruses and quantitation of effector T cells needed to cause disease

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; AUTOIMMUNE DISEASE; CELL COUNT; CROSS REACTION; CYTOTOXIC T LYMPHOCYTE; DIABETES MELLITUS; DIABETOGENESIS; EFFECTOR CELL; INSULIN DEPENDENT DIABETES MELLITUS; MODEL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS; VIRUS PATHOGENESIS;

EID: 0034011436     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.7.3284-3292.2000     Document Type: Article
Times cited : (47)

References (42)
  • 1
    • 0021225388 scopus 로고
    • Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice: role in suppression of cytotoxic T lymphocyte response and viral persistence
    • Ahmed, R., A. Salmi, L. D. Butler, J. M. Chiller, and M. B. A. Oldstone. 1984. Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice: role in suppression of cytotoxic T lymphocyte response and viral persistence. J. Exp. Med. 160:521-540.
    • (1984) J. Exp. Med. , vol.160 , pp. 521-540
    • Ahmed, R.1    Salmi, A.2    Butler, L.D.3    Chiller, J.M.4    Oldstone, M.B.A.5
  • 3
    • 0028873681 scopus 로고
    • Virus-induced immunosuppression: Immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression
    • Borrow, P., C. F. Evans, and M. B. A. Oldstone. 1995. Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression. J. Virol. 69:1059-1070.
    • (1995) J. Virol. , vol.69 , pp. 1059-1070
    • Borrow, P.1    Evans, C.F.2    Oldstone, M.B.A.3
  • 4
    • 0019602660 scopus 로고
    • Monoclonal antibodies to lymphocytic choriomeningitis and pichinde viruses: Generation, characterization, and cross-reactivity with other arenaviruses
    • Buchmeier, M. J., H. A. Lewicki, O. Tomori, and M. B. A. Oldstone. 1981 Monoclonal antibodies to lymphocytic choriomeningitis and pichinde viruses: generation, characterization, and cross-reactivity with other arenaviruses. Virology 113:73-85.
    • (1981) Virology , vol.113 , pp. 73-85
    • Buchmeier, M.J.1    Lewicki, H.A.2    Tomori, O.3    Oldstone, M.B.A.4
  • 6
    • 0020960565 scopus 로고
    • Genomic and biological variation among commonly used lymphocytic choriomeningitis virus strains
    • Dutko, F. J., and M. B. A. Oldstone. 1983. Genomic and biological variation among commonly used lymphocytic choriomeningitis virus strains. J. Gen. Virol. 64:1689-1698.
    • (1983) J. Gen. Virol. , vol.64 , pp. 1689-1698
    • Dutko, F.J.1    Oldstone, M.B.A.2
  • 7
    • 0026599764 scopus 로고
    • Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes
    • Eisenlohr, L. C., J. W. Yewdell, and J. R. Bennink. 1992. Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes. J. Exp. Med. 175:481-487.
    • (1992) J. Exp. Med. , vol.175 , pp. 481-487
    • Eisenlohr, L.C.1    Yewdell, J.W.2    Bennink, J.R.3
  • 8
    • 1842324684 scopus 로고
    • Diabetes mellitus: Definition, classification, tests
    • L. DeGroot (ed.), Grune and Stratton, New York, N.Y.
    • Fajans, S. S. 1994. Diabetes mellitus: definition, classification, tests, p. 1411. In L. DeGroot (ed.), Endocrinology. Grune and Stratton, New York, N.Y.
    • (1994) Endocrinology , pp. 1411
    • Fajans, S.S.1
  • 9
    • 0015223187 scopus 로고
    • High frequency of diabetes mellitus in young adults with congenital rubella
    • Forrest, J., M. A. Menser, and J. Burgess. 1991. High frequency of diabetes mellitus in young adults with congenital rubella. Lancet i:332-334.
    • (1991) Lancet , vol.1 , pp. 332-334
    • Forrest, J.1    Menser, M.A.2    Burgess, J.3
  • 10
    • 0015809314 scopus 로고
    • Coxsackie viruses and diabetes mellitus
    • Gamble, D. R., K. W. Taylor, and H. Cumming. 1973. Coxsackie viruses and diabetes mellitus. Br. Med. J. 4:260-262.
    • (1973) Br. Med. J. , vol.4 , pp. 260-262
    • Gamble, D.R.1    Taylor, K.W.2    Cumming, H.3
  • 11
    • 0031874342 scopus 로고    scopus 로고
    • Diabetes induced by coxsackie virus: Initiation by bystander damage and not molecular mimicry
    • Horwitz, M. S., L. M. Bradley, J. Harbertson, T. Krahl, J. Lee, and N. Sarvetnick. 1998. Diabetes induced by coxsackie virus: initiation by bystander damage and not molecular mimicry. Nat. Med. 4:781-785.
    • (1998) Nat. Med. , vol.4 , pp. 781-785
    • Horwitz, M.S.1    Bradley, L.M.2    Harbertson, J.3    Krahl, T.4    Lee, J.5    Sarvetnick, N.6
  • 12
    • 0019327043 scopus 로고
    • Pancreatic islet cell damage in children with fatal viral infections
    • Jenson, A. B., H. S. Rosenberg, and A. L. Notkins. 1980. Pancreatic islet cell damage in children with fatal viral infections. Lancet ii:354-358.
    • (1980) Lancet , vol.2 , pp. 354-358
    • Jenson, A.B.1    Rosenberg, H.S.2    Notkins, A.L.3
  • 16
    • 0030060155 scopus 로고    scopus 로고
    • Unresponsiveness to a self-peptide of mouse lysozyme owing to hindrance of T cell receptor-major histocompatibility complex/peptide interaction caused by flanking epitopic residues
    • Moudgil, K. D., I. S. Grewal, P. E. Jensen, and E. E. Sercarz. 1996. Unresponsiveness to a self-peptide of mouse lysozyme owing to hindrance of T cell receptor-major histocompatibility complex/peptide interaction caused by flanking epitopic residues. J. Exp. Med. 183:535-546.
    • (1996) J. Exp. Med. , vol.183 , pp. 535-546
    • Moudgil, K.D.1    Grewal, I.S.2    Jensen, P.E.3    Sercarz, E.E.4
  • 18
    • 0003408870 scopus 로고
    • Publication no. 95-1468. National Institutes of Health, Bethesda, Md.
    • National Diabetes Data Group. 1995. Diabetes in America, 2nd ed. Publication no. 95-1468. National Institutes of Health, Bethesda, Md.
    • (1995) Diabetes in America, 2nd Ed.
  • 19
    • 0013592977 scopus 로고
    • Virus induced autoimmunity
    • A. L. Notkins and M. B. A. Oldstone (ed.), Springer-Verlag, Heidelberg, Germany
    • Notkins, A. L., T. Onodera, and B. Prabhakar. 1984. Virus induced autoimmunity, p. 210-215. In A. L. Notkins and M. B. A. Oldstone (ed.), Concepts in viral pathogenesis. Springer-Verlag, Heidelberg, Germany.
    • (1984) Concepts in Viral Pathogenesis , pp. 210-215
    • Notkins, A.L.1    Onodera, T.2    Prabhakar, B.3
  • 20
    • 0025755292 scopus 로고
    • Ablation of tolerance and induction of diabetes by virus infection in viral antigen transgenic mice
    • Ohashi, P., S. Oehen, K. Buerki, et al. 1991. Ablation of tolerance and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 65:305-317.
    • (1991) Cell , vol.65 , pp. 305-317
    • Ohashi, P.1    Oehen, S.2    Buerki, K.3
  • 21
    • 0025291899 scopus 로고
    • Viruses as therapeutic agents. II. Viral reassortants map prevention of insulin-dependent diabetes mellitus to the small RNA of lymphocytic choriomeningitis virus
    • Oldstone, M. B. A., R. Ahmed, and M. Salvato. 1990. Viruses as therapeutic agents. II. Viral reassortants map prevention of insulin-dependent diabetes mellitus to the small RNA of lymphocytic choriomeningitis virus. J. Exp. Med. 171:2091-2100.
    • (1990) J. Exp. Med. , vol.171 , pp. 2091-2100
    • Oldstone, M.B.A.1    Ahmed, R.2    Salvato, M.3
  • 22
    • 0025754853 scopus 로고
    • Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response
    • Oldstone, M. B. A., N. Nerenberg, P. Southern, J. Price, and H. Lewicki. 1991. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response. Cell 65:319-331.
    • (1991) Cell , vol.65 , pp. 319-331
    • Oldstone, M.B.A.1    Nerenberg, N.2    Southern, P.3    Price, J.4    Lewicki, H.5
  • 23
    • 0021271733 scopus 로고
    • Virus persists in beta cells of islets of Langerhans and is associated with chemical manifestations of diabetes
    • Oldstone, M. B. A., P. Southern, M. Rodriguez, and P. Lampert. 1984. Virus persists in beta cells of islets of Langerhans and is associated with chemical manifestations of diabetes. Science 224:1440-1443.
    • (1984) Science , vol.224 , pp. 1440-1443
    • Oldstone, M.B.A.1    Southern, P.2    Rodriguez, M.3    Lampert, P.4
  • 24
    • 0033541378 scopus 로고    scopus 로고
    • Use of a high-affinity peptide that aborts MHC restricted cytotoxic T lymphocyte activity against multiple viruses in vitro and virus-induced immunopathologic disease in vivo
    • Oldstone, M. B. A., M. von Herrath, H. Lewicki, D. Hudrisier, J. L. Whitton, and J. E. Gairin. 1999. Use of a high-affinity peptide that aborts MHC restricted cytotoxic T lymphocyte activity against multiple viruses in vitro and virus-induced immunopathologic disease in vivo. Virology 256:246-257.
    • (1999) Virology , vol.256 , pp. 246-257
    • Oldstone, M.B.A.1    Von Herrath, M.2    Lewicki, H.3    Hudrisier, D.4    Whitton, J.L.5    Gairin, J.E.6
  • 25
    • 0023757321 scopus 로고
    • The significance of concordance rate for type 1 (insulin-dependent) diabetes in identical twins
    • Olmos, P., R. A'Hern, D. A. Heaton, et al. 1988. The significance of concordance rate for type 1 (insulin-dependent) diabetes in identical twins. Diabetologia 31:747-750.
    • (1988) Diabetologia , vol.31 , pp. 747-750
    • Olmos, P.1    A'Hern, R.2    Heaton, D.A.3
  • 27
    • 0029078283 scopus 로고
    • Immunoglobulin variable gene analysis of human autoantibodies reveals antigen-driven immune response to glutamate decarboxylase in type 1 diabetes mellitus
    • Richter, W., K. M. Jury, D. Loeffler, B. J. Manfras, T. H. Eiermann, and B. O. Boehm. 1995. Immunoglobulin variable gene analysis of human autoantibodies reveals antigen-driven immune response to glutamate decarboxylase in type 1 diabetes mellitus. Eur. J. Immunol. 25:1703-1712.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1703-1712
    • Richter, W.1    Jury, K.M.2    Loeffler, D.3    Manfras, B.J.4    Eiermann, T.H.5    Boehm, B.O.6
  • 28
    • 0031902438 scopus 로고    scopus 로고
    • DNA immunization with minigenes: Low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination
    • Rodriguez, F., L. L. An, S. Harkins, J. Zhang, M. Yokoyama, G. Widera, J. T. Fuller, C. Kincaid, I. L. Campbell, and J. L. Whitton. 1998. DNA immunization with minigenes: low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination. J. Virol. 72:5174-5181.
    • (1998) J. Virol. , vol.72 , pp. 5174-5181
    • Rodriguez, F.1    An, L.L.2    Harkins, S.3    Zhang, J.4    Yokoyama, M.5    Widera, G.6    Fuller, J.T.7    Kincaid, C.8    Campbell, I.L.9    Whitton, J.L.10
  • 29
    • 0023908256 scopus 로고
    • Virus-lymphocyte interactions. IV. Molecular characterization of LCMV Armstrong (CTL+) and that of its variant, Clone 13 (CTL-)
    • Salvato, M., E. Shimomaye, P. Southern, and M. B. A. Oldstone. 1988. Virus-lymphocyte interactions. IV. Molecular characterization of LCMV Armstrong (CTL+) and that of its variant, Clone 13 (CTL-). Virology 164:517-522.
    • (1988) Virology , vol.164 , pp. 517-522
    • Salvato, M.1    Shimomaye, E.2    Southern, P.3    Oldstone, M.B.A.4
  • 31
    • 0028143519 scopus 로고
    • T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele
    • Tian, J., P. V. Lehmann, and D. L. Kaufman. 1994. T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele. J. Exp. Med. 180:1979-1984.
    • (1994) J. Exp. Med. , vol.180 , pp. 1979-1984
    • Tian, J.1    Lehmann, P.V.2    Kaufman, D.L.3
  • 32
    • 0028446546 scopus 로고
    • How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model
    • von Herrath, M., J. Dockter, and M. B. A. Oldstone. 1994. How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model. Immunity 1:231-242.
    • (1994) Immunity , vol.1 , pp. 231-242
    • Von Herrath, M.1    Dockter, J.2    Oldstone, M.B.A.3
  • 33
    • 0032213343 scopus 로고    scopus 로고
    • In vivo treatment with a MHC class I restricted blocking peptide can prevent virus-induced autoimmune diabetes
    • von Herrath, M. G., B. Coon, H. Lewicki, H. Mazarguil, J. E. Gairin, and M. B. A. Oldstone. 1998. In vivo treatment with a MHC class I restricted blocking peptide can prevent virus-induced autoimmune diabetes. J. Immunol. 161:5087-5096.
    • (1998) J. Immunol. , vol.161 , pp. 5087-5096
    • Von Herrath, M.G.1    Coon, B.2    Lewicki, H.3    Mazarguil, H.4    Gairin, J.E.5    Oldstone, M.B.A.6
  • 34
    • 0028080014 scopus 로고
    • Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus
    • von Herrath, M. G., J. Dockter, M. Nerenberg, J. E. Gairin, and M. B. A. Oldstone. 1994. Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus. J. Exp. Med. 180:1901-1910.
    • (1994) J. Exp. Med. , vol.180 , pp. 1901-1910
    • Von Herrath, M.G.1    Dockter, J.2    Nerenberg, M.3    Gairin, J.E.4    Oldstone, M.B.A.5
  • 36
    • 0029551987 scopus 로고
    • Coexpression of B7.1 and viral ("self") transgenes in pancreatic β cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes
    • von Herrath, M. G., S. Guerder, H. Lewicki, R. A. Flavell, and M. B. A. Oldstone. 1995. Coexpression of B7.1 and viral ("self") transgenes in pancreatic β cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes. Immunity 3:727-738.
    • (1995) Immunity , vol.3 , pp. 727-738
    • Von Herrath, M.G.1    Guerder, S.2    Lewicki, H.3    Flavell, R.A.4    Oldstone, M.B.A.5
  • 37
    • 0031051747 scopus 로고    scopus 로고
    • Interferon-γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus
    • von Herrath, M. G., and M. B. A. Oldstone. 1997. Interferon-γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus. J. Exp. Med. 185:531-539.
    • (1997) J. Exp. Med. , vol.185 , pp. 531-539
    • Von Herrath, M.G.1    Oldstone, M.B.A.2
  • 38
    • 0023840826 scopus 로고
    • Analyses of the cytotoxic T lymphocyte responses to glycoprotein and nucleoprotein components of lymphocytic choriomeningitis virus
    • Whitton, J. L., P. J. Southern, and M. B. A. Oldstone. 1988. Analyses of the cytotoxic T lymphocyte responses to glycoprotein and nucleoprotein components of lymphocytic choriomeningitis virus. Virology 162:321-327.
    • (1988) Virology , vol.162 , pp. 321-327
    • Whitton, J.L.1    Southern, P.J.2    Oldstone, M.B.A.3
  • 39
    • 0024474289 scopus 로고
    • Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: An inimunodominant region which induces nonreciprocal CTL cross-reactivity
    • Whitton, J. L., A. Tishon, H. Lewicki, J. Gebhard, T. Cook, M. Salvato, E. Joly, and M. B. A. Oldstone. 1989. Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an inimunodominant region which induces nonreciprocal CTL cross-reactivity. J. Virol. 63:4303-4310.
    • (1989) J. Virol. , vol.63 , pp. 4303-4310
    • Whitton, J.L.1    Tishon, A.2    Lewicki, H.3    Gebhard, J.4    Cook, T.5    Salvato, M.6    Joly, E.7    Oldstone, M.B.A.8
  • 40
    • 0028440958 scopus 로고
    • Possible mechanisms of autoantibody production and the connection of viral infections in human autoimmune diseases
    • Yamamoto, D. 1994. Possible mechanisms of autoantibody production and the connection of viral infections in human autoimmune diseases. J. Exp. Med. 173:75-82.
    • (1994) J. Exp. Med. , vol.173 , pp. 75-82
    • Yamamoto, D.1
  • 41
    • 0028968744 scopus 로고
    • DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection
    • Yokoyama, M., J. Zhang, and J. L. Whitton. 1995. DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection. J. Virol. 69:2684-2688.
    • (1995) J. Virol. , vol.69 , pp. 2684-2688
    • Yokoyama, M.1    Zhang, J.2    Whitton, J.L.3
  • 42
    • 0018799757 scopus 로고
    • Virus-induced diabetes mellitus: Isolation of a virus from the pancreas of a child with diabetic ketoacidosis
    • Yoon, J. W., M. Austin, T. Onodera, and A. L. Notkins. 1979. Virus-induced diabetes mellitus: isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N. Engl. J. Med. 300:1173-1179.
    • (1979) N. Engl. J. Med. , vol.300 , pp. 1173-1179
    • Yoon, J.W.1    Austin, M.2    Onodera, T.3    Notkins, A.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.