Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 39, 2014, Pages 14141-14146

  Gianni, Stefano ^a,b   Camilloni, Carlo ^b   Giri, Rajanish ^a   Toto, Angelo ^a   Bonetti, Daniela ^a   Morrone, Angela ^a   Sormanni, Pietro ^b   Brunori, Maurizio ^a   Vendruscolo, Michele ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FRATAXIN; IRON BINDING PROTEIN; PROTEIN AGGREGATE; PROTEIN BINDING; RECOMBINANT PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO ACID SUBSTITUTION; BIOPHYSICS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR DYNAMICS; PROTEIN FOLDING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; BIOPHYSICAL PHENOMENA; HUMANS; IRON-BINDING PROTEINS; KINETICS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; PROTEIN AGGREGATES; PROTEIN BINDING; PROTEIN FOLDING; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84907573466     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1405233111     Document Type: Article

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