Transient aggregates in protein folding are easily mistaken for folding intermediates

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 12, 1997, Pages 6084-6086

  Silow, Maria ^a   Oliveberg, Mikael ^a  

^a CHEMICAL CENTER   (Sweden)

Author keywords

Aggregation artefacts; Off pathway intermediates; UIA spliceosomal protein

Indexed keywords

MONOMER; PROTEIN;

ARTICLE; ARTIFACT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STABILITY; SPLICEOSOME;

ARTIFACTS; CALORIMETRY; GUANIDINE; GUANIDINES; HUMANS; KINETICS; MACROMOLECULAR SUBSTANCES; PEPTIDES; PLANT PROTEINS; PROTEIN DENATURATION; PROTEIN FOLDING; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; RNA-BINDING PROTEINS; SERINE PROTEINASE INHIBITORS; SPLICEOSOMES;

EID: 0030958760     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.12.6084     Document Type: Article

References (27)

1. Udgaonkar, J. B. & Baldwin R. L. (1988) Nature (London) 335, 700-704.
2. Roder, H., Elöve, G. A. & Englander S. W. (1988) Nature (London) 335, 694-699.
3. Matouschek, A., Kellis, J. T., Serrano, L., Bycroft, M. & Fersht, A. R. (1990) Nature (London) 346, 440-445.
4. Kim, P. S. & Baldwin R. L. (1990) Annu. Rev. Biochem. 59, 631-660.
5. Radford, S. E, Dobson, C. M. & Evans, P. A. (1992) Nature (London) 358, 302-307.
6. Bai, Y., Sosnick, T. R., Mayne, L. & Englander, S. W. (1995) Science 269, 192-197.
7. Jackson, S. E. & Fersht A. R. (1991) Biochemistry 30, 10428-10435.
8. Alexander, P., Orban, J. & Bryan, P. (1992) Biochemistry 31, 7243-7248.
9. Viguera, A. R., Martinez, J. C., Filimonov, V. V., Mateo, P. L. & Serrano, L. (1994) Biochemistry 33, 2142-2150.
10. Kuszewski, J., Clore, G. M. & Gronenborn, A. M. (1994) Protein Sci. 3, 1945-1952.
11. Kragelund, B. B., Robinson, C. V., Knudsen, V., Dobson, C. M. & Poulsen, F. M. (1995) Biochemistry 34, 7217-7224.
12. Schindler, T. S., Herrier, M., Marahiel, M. A. & Schmid, F. X. (1995) Nat. Struct. Biol. 2, 663-673.
13. Khorasanizadeh, S., Peters, I. D., Butt, T. R. & Roder, H. (1993) Biochemistry 32, 7054-7063.
14. Oliveberg, M., Tan, Y. J. & Fersht, A. R. (1995) Proc. Natl. Acad. Sci. USA 92, 8926-8929.
15. Shakhnovich, E. I. & Finkelstein A. V. (1989) Biopolymers 28, 1667-1680.
16. Chan, H. S. & Dill K. A. (1994) J. Chem. Phys. 100, 9238-9275.
17. Kiefhaber, T. (1995) Proc. Natl. Acad. Sci. USA 92, 9029-9033.
18. Fersht, A. R. (1995) Proc. Natl. Acad. Sci. USA 92, 10869-10873.
19. Mirny, L. A., Abkevich, V. & Shakhnovich, E. I. (1996) Folding and Design 1, 103-116.
20. Nagai, K., Oubridge, C., Jessen, T.-H., Li, J. & Evans, P. R. (1990) Nature (London) 348, 515-520.
21. Simpson, G. G., Clark, G. P., Rothnie, H. M., Boelens, W., van Venrooij, W. & Brown, J. W. S. (1995) EMBO J. 14, 4540-4550.
22. Pace, C. N. (1986) Methods Enzymol. 131, 266-279.
23. Muñoz, V., Lopez, E. M., Jager, M. & Serrano, L.(1994) Biochemistry 33, 5858-5866.
24. Dill, K. A. & Shortle, D. (1991) Annu. Rev. Biochem. 60, 795-825.
25. Brems, D. N. (1988) Biochemistry 27, 4541-4546.
26. Goldberg, M. E., Rudolph, R. & Jaenicke, R. (1991) Biochemistry 30, 2790-2797.
27. Pecorari, F., Minard, P., Desmadril, M. & Yon, J. M. (1996) J. Biol. Chem. 271, 5270-5276.