Prohibitin-Mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Gatsi, Roxani ^a   Schulze, Bettina ^b   Rodríguez Palero, María Jesús ^a   Hernando Rodríguez, Blanca ^a   Baumeister, Ralf ^b   Artal Sanz, Marta ^a,b  

^a UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DAF 2 PROTEIN; FLOXURIDINE; INSULIN; INSULIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROHIBITIN; REGULATOR PROTEIN; RICT 1 PROTEIN; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SOMATOMEDIN; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN SERINE THREONINE KINASE; REPRESSOR PROTEIN; SGK-1 PROTEIN, C ELEGANS; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ADULT; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; EMBRYO; HOMEOSTASIS; LIFE EXTENSION; LIFESPAN; LOSS OF FUNCTION MUTATION; MITOCHONDRION; NONHUMAN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; ANIMAL; ENZYMOLOGY; LIFE EXPECTANCY; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; INSULIN; LIFE EXPECTANCY; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; SOMATOMEDINS; STRESS, PHYSIOLOGICAL; TOR SERINE-THREONINE KINASES;

EID: 84907546613     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107671     Document Type: Article

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