The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans

Aging Cell

Volumn 7, Issue 6, 2008, Pages 879-893

  Evans, Eric A ^a   Chen, Will C ^a   Tan, Man Wah ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; C. elegans; Calorie restriction; Germline; Innate immunity; Insulin IGF 1signalling; Lifespan; Pseudomonas aeruginosa

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; MUTANT PROTEIN; PROTEIN DAF 2; PROTEIN KINASE B; PROTEIN KINASE B BETA; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

AGING; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; CAENORHABDITIS ELEGANS; CALORIC RESTRICTION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE MUTATION; IMMUNOREGULATION; INNATE IMMUNITY; LIFESPAN; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SIGNAL TRANSDUCTION; WILD TYPE;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; IMMUNITY, INNATE; INSULIN; LONGEVITY; MALE; MUTATION; PROTO-ONCOGENE PROTEINS C-AKT; PSEUDOMONAS INFECTIONS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

BACTERIA (MICROORGANISMS); CAENORHABDITIS ELEGANS; PSEUDOMONAS AERUGINOSA;

EID: 56849110390     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2008.00435.x     Document Type: Article

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