Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy

EMBO Molecular Medicine

Volumn 5, Issue 1, 2013, Pages 80-91

  Andres Mateos, Eva ^a   Brinkmeier, Heinrich ^b   Burks, Tyesha N ^a   Mejias, Rebeca ^a   Files, Daniel C ^a   Steinberger, Martin ^b   Soleimani, Arshia ^a   Marx, Ruth ^a   Simmers, Jessica L ^a   Lin, Benjamin ^a   Finanger Hedderick, Erika ^a   Marr, Tom G ^c   Lin, Brian M ^a   Hourdé, Christophe ^d   Leinwand, Leslie A ^e   Kuhl, Dietmar ^f   Föller, Michael ^g   Vogelsang, Silke ^b   Hernandez Diaz, Ivan ^h   Vaughan, Dana K ⁱ   Alvarez de la Rosa, Diego ^h   Lang, Florian ^g   Cohn, Ronald D ^a   more..

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c Hiberna Corporation   (United States)

^d CNRS   (France)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^g UNIVERSITY OF TÜBINGEN   (Germany)

^h UNIVERSIDAD DE LA LAGUNA   (Spain)

ⁱ UNIVERSITY OF WISCONSIN OSHKOSH   (United States)

Author keywords

Hibernation; Muscle atrophy; Muscle homeostasis; Muscle hypertrophy; SGK1

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; TRANSCRIPTION FACTOR FKHRL1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOWN REGULATION; ENZYME INACTIVATION; HIBERNATION; HOMEOSTASIS; IMMOBILIZATION; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE FUNCTION; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SKELETAL MUSCLE; SKELETAL MUSCLE ATROPHY; STARVATION;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; ENZYME ACTIVATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HIBERNATION; HOMEOSTASIS; IMMEDIATE-EARLY PROTEINS; MALE; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SCIURIDAE; SIGNAL TRANSDUCTION; STARVATION; TOR SERINE-THREONINE KINASES;

EID: 84871997810     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201201443     Document Type: Article

References (36)

1. Agbulut O, Vignaud A, Hourde C, Mouisel E, Fougerousse F, Butler-Browne GS, Ferry A (2009) Slow myosin heavy chain expression in the absence of muscle activity. Am J Physiol Cell Physiol 296: C205- C214
2. Aoyama T, Matsui T, Novikov M, Park J, Hemmings B, Rosenzweig A (2005) Serum and glucocorticoid-responsive kinase-1 regulates cardiomyocyte survival and hypertrophic response. Circulation 111: 1652- 1659
3. Arteaga MF, Alvarez de la Rosa D, Alvarez JA, Canessa CM (2007) Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1. Mol Biol Cell 18: 2072- 2080
4. Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM (2006) An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc Natl Acad Sci USA 103: 11178- 11183
5. Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC, Glass DJ, et al (2001) Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol 3: 1014- 1019
6. Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, et al (2007) Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell 129: 1065- 1079
7. Briguet A, Courdier-Fruh I, Foster M, Meier T, Magyar JP (2004) Histological parameters for the quantitative assessment of muscular dystrophy in the mdx-mouse. Neuromuscul Disord 14: 675- 682
8. Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME (2001) Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol 21: 952- 965
9. Burks TN, Andres-Mateos E, Marx R, Mejias R, Van Erp C, Simmers JL, Walston JD, Ward CW, Cohn RD (2011) Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. Sci Transl Med 3: 82ra37
10. Cohn RD, van Erp C, Habashi JP, Soleimani AA, Klein EC, Lisi MT, Gamradt M, ap Rhys CM, Holm TM, Loeys BL, et al (2007) Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nat Med 13: 204- 210
11. Degens H, Alway SE (2006) Control of muscle size during disuse, disease, and aging. Int J Sports Med 27: 94- 99
12. Glass DJ (2003) Signalling pathways that mediate skeletal muscle hypertrophy and atrophy. Nat Cell Biol 5: 87- 90
13. Glass DJ (2010) Signaling pathways perturbing muscle mass. Curr Opin Clin Nutr Metab Care 13: 225- 229
14. Goncalves MD, Pistilli EE, Balduzzi A, Birnbaum MJ, Lachey J, Khurana TS, Ahima RS (2010) Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition. PLoS ONE 5: e12707
15. Grumati P, Coletto L, Sabatelli P, Cescon M, Angelin A, Bertaggia E, Blaauw B, Urciuolo A, Tiepolo T, Merlini L, et al (2010) Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration. Nat Med 16: 1313- 1320
16. Hudson NJ, Franklin CE (2002) Maintaining muscle mass during extended disuse: aestivating frogs as a model species. J Exp Biol 205: 2297- 2303
17. Izumiya Y, Hopkins T, Morris C, Sato K, Zeng L, Viereck J, Hamilton JA, Ouchi N, LeBrasseur NK, Walsh K (2008) Fast/glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice. Cell Metab 7: 159- 172
18. Jagoe RT, Lecker SH, Gomes M, Goldberg AL (2002) Patterns of gene expression in atrophying skeletal muscles: response to food deprivation. FASEB J 16: 1697- 1712
19. Klaude M, Fredriksson K, Tjader I, Hammarqvist F, Ahlman B, Rooyackers O, Wernerman J (2007) Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis. Clin Sci (Lond) 112: 499- 506
20. Kobayashi T, Cohen P (1999) Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem J 339(Pt 2), 319- 328
21. Lai KM, Gonzalez M, Poueymirou WT, Kline WO, Na E, Zlotchenko E, Stitt TN, Economides AN, Yancopoulos GD, Glass DJ (2004) Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy. Mol Cell Biol 24: 9295- 9304
22. Lalioti M, Heath J (2001) A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli. Nucleic Acids Res 29: E14
23. Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N, Vallon V (2006) (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol Rev 86: 1151- 1178
24. Lee K, So H, Gwag T, Ju H, Lee JW, Yamashita M, Choi I (2010) Molecular mechanism underlying muscle mass retention in hibernating bats: role of periodic arousal. J Cell Physiol 222: 313- 319
25. Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, Burden SJ, Di Lisi R, Sandri C, Zhao J, et al (2007) FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 6: 458- 471
26. Morin P, Jr, Storey KB (2009) Mammalian hibernation: differential gene expression and novel application of epigenetic controls. Int J Dev Biol 53: 433- 442
27. Musaro A, McCullagh K, Paul A, Houghton L, Dobrowolny G, Molinaro M, Barton ER, Sweeney HL, Rosenthal N (2001) Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat Genet 27: 195- 200
28. Nowell MM, Choi H, Rourke BC (2011) Muscle plasticity in hibernating ground squirrels (Spermophilus lateralis) is induced by seasonal, but not low-temperature, mechanisms. J Comp Physiol B 181: 147- 164
29. Saini A, Faulkner S, Al-Shanti N, Stewart C (2009) Powerful signals for weak muscles. Ageing Res Rev 8: 251- 267
30. Schertzer JD, Plant DR, Lynch GS (2006) Optimizing plasmid-based gene transfer for investigating skeletal muscle structure and function. Mol Ther 13: 795- 803
31. Shavlakadze T, Grounds M (2006) Of bears, frogs, meat, mice and men: complexity of factors affecting skeletal muscle mass and fat. Bioessays 28: 994- 1009
32. Song YH, Godard M, Li Y, Richmond SR, Rosenthal N, Delafontaine P (2005) Insulin-like growth factor I-mediated skeletal muscle hypertrophy is characterized by increased mTOR-p70S6K signaling without increased Akt phosphorylation. J Investig Med 53: 135- 142
33. Vaughan DK, Gruber AR, Michalski ML, Seidling J, Schlink S (2006) Capture, care, and captive breeding of 13-lined ground squirrels, Spermophilus tridecemlineatus. Lab Anim (NY) 35: 33- 40
34. Webster MK, Goya L, Ge Y, Maiyar AC, Firestone GL (1993) Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Mol Cell Biol 13: 2031- 2040
35. Wulff P, Vallon V, Huang DY, Volkl H, Yu F, Richter K, Jansen M, Schlunz M, Klingel K, Loffing J, et al (2002) Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest 110: 1263- 1268
36. Zhao J, Brault JJ, Schild A, Cao P, Sandri M, Schiaffino S, Lecker SH, Goldberg AL (2007) FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 6: 472- 483