Model-based integrated optimization and evaluation of a multi-step ion exchange chromatography

Separation and Purification Technology

Volumn 136, Issue , 2014, Pages 207-222

  Huuk, Thiemo C ^a   Hahn, Tobias ^a   Osberghaus, Anna ^a   Hubbuch, Jürgen ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Critical process parameter (CPP); Downstream Process Development (DSP); Ion exchange chromatography (IEX); Model based process optimization; Steric mass action isotherm (SMA)

Indexed keywords

CRITICAL PROCESS PARAMETERS; DOWNSTREAM PROCESS DEVELOPMENT; INTEGRATED OPTIMIZATION; ION EXCHANGE CHROMATOGRAPHY; MULTI-STEP; STERIC MASS ACTION;

EID: 84907495064     PISSN: 13835866     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seppur.2014.09.012     Document Type: Article

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