Detection, quantification, and propagation of uncertainty in high-throughput experimentation by Monte Carlo methods

Chemical Engineering and Technology

Volumn 35, Issue 8, 2012, Pages 1456-1464

  Osberghaus, A ^a   Baumann, P ^a   Hepbildikler, S ^b   Nath, S ^b   Haindl, M ^b   von Lieres, E ^c   Hubbuch, J ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

Chromatography; Monte Carlo method; Robotic platform; Simulation; Uncertainty propagation

Indexed keywords

96-WELL FORMAT; BINDING STUDIES; HIGH THROUGHPUT EXPERIMENTATION; HIGH-THROUGHPUT; MONTE CARLO; PROOF OF CONCEPT; PROPAGATION OF UNCERTAINTIES; ROBOTIC PLATFORMS; SIMULATION; SIMULATION ALGORITHMS; SIMULATION-BASED ANALYSIS; UNCERTAINTY PROPAGATION;

CHROMATOGRAPHY; EXPERIMENTS; ROBOTICS; UNCERTAINTY ANALYSIS;

MONTE CARLO METHODS;

EID: 84864314003     PISSN: 09307516     EISSN: 15214125     Source Type: Journal    
DOI: 10.1002/ceat.201100610     Document Type: Article

References (19)

1. ICH Harmonised Tripartite Guideline Pharmaceutical Development Q8 (R2), International Conference of Harmonisation, Geneva 2009.
2. H. Wan, M. Rehngren, J. Chromatogr. A 2006, 1102 (1-2), 125.
3. A. Staby, R.H. Jensen, M. Bensch, J. Krarup, J. Nielsen, M. Lund, S. Kidal, T.B. Hansen, I.H. Jensen, J. Chromatogr. A 2007, 1164, 82.
4. M. Bensch, B. Selbach, J. Hubbuch, Chem. Eng. Sci. 2007, 62 (7), 2011.
5. A. Susanto, K. Treier, E. Knieps-Grünhagen, E. von Lieres, J. Hubbuch, Chem.Eng. Technol. 2009, 32 (1), 140.
6. W. Kessel, ISO/BIPM Guide: Uncertainty of Measurement, 1999.
7. X. Fuentes-Arderiu, Clin. Chem. 2000, 46 (9), 1437.
8. C. F. Dietrich, Uncertainty, Calibration, and Probability: The Statistics of Scientific and Industrial Measurement, 2nd ed., Adam Hilger Series on Measurement Science and Technology, Institute of Physics Pub., Bristol 1991.
9. J.F. Ogilvie, Comput. Chem. 1921, 8 (3), 205.
10. C.E. Efstathiou, Anal. Chem. 1982, 54 (9), 1525.
11. A.S. Kurup, H.J. Subramani, M.T. Harris, Sep. Purif. Technol. 2008, 62, 582.
12. D. Hibbert, Anal. Chim. Acta 2001, 443 (2), 205.
13. N. Faber, Anal. Chim. Acta 2001, 439 (2), 193.
14. E. Hund, D.L. Massart, J. Smeyers-Verbeke, Anal. Chim. Acta 2003, 480, 39.
15. L. Michaelis, M.L. Menten, Biochem. Z. 1913, 49, 333.
16. B. Efron, R. J. Tibshirani, An Introduction to the Bootstrap, 1st ed., CRC Monographs on Statistics & Applied Probability, Vol. 57, Chapman and Hall, London 1994.
17. J. Tellinghuisen, J. Phys. Chem. A 2001, 105 (15), 3917.
18. T. Herrmann, M. Schröder, J. Hubbuch, Biotechnol. Prog. 2006, 22 (3), 914.
19. R. Ritchie, T. Prvan, J. Theor. Biol. 1996, 178 (3), 239.