-
1
-
-
0023740954
-
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
-
Hirsch E, Graybiel AM, Agid YA (1988) Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 334: 345-348.
-
(1988)
Nature
, vol.334
, pp. 345-348
-
-
Hirsch, E.1
Graybiel, A.M.2
Agid, Y.A.3
-
2
-
-
0033608187
-
Parkinson disease in twins: An etiologie study
-
Tanner CM, Ottman R, Goldman SM, Ellenberg J, Chan P, et al. (1999) Parkinson disease in twins: an etiologie study. JAMA 281: 341-346.
-
(1999)
JAMA
, vol.281
, pp. 341-346
-
-
Tanner, C.M.1
Ottman, R.2
Goldman, S.M.3
Ellenberg, J.4
Chan, P.5
-
3
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, et al. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276: 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
-
4
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, et al. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392: 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
-
5
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy E, Boyer R, Auburger G, Leube B, Ulm G, et al. (1998) The ubiquitin pathway in Parkinson's disease. Nature 395: 451 -452.
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
-
6
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, et al. (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 18: 106-108.
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
-
7
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, et al. (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299: 256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
-
8
-
-
0031566231
-
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras
-
Nagakubo D, Taira T, Kitaura H, Ikeda M, Tamai K, et al. (1997) DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem Biophys Res Commun 231: 509-513.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 509-513
-
-
Nagakubo, D.1
Taira, T.2
Kitaura, H.3
Ikeda, M.4
Tamai, K.5
-
9
-
-
0030919860
-
Discriminant analysis indicates a single sperm protein (SP22) is predictive of fertility following exposure to epididymal toxicants
-
Klinefelter GR, Laskey JW, Ferrell J, Suarez JD, Roberts NL (1997) Discriminant analysis indicates a single sperm protein (SP22) is predictive of fertility following exposure to epididymal toxicants. J Androl 18: 139-150.
-
(1997)
J Androl
, vol.18
, pp. 139-150
-
-
Klinefelter, G.R.1
Laskey, J.W.2
Ferrell, J.3
Suarez, J.D.4
Roberts, N.L.5
-
10
-
-
0034892917
-
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36
-
van Duijn CM, Dekker MC, Bonifati V, Galjaard RJ, Houwing-Duistermaat JJ, et al. (2001) Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36. Am J Hum Genet 69: 629-634.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 629-634
-
-
Van Duijn, C.M.1
Dekker, M.C.2
Bonifati, V.3
Galjaard, R.J.4
Houwing-Duistermaat, J.J.5
-
11
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahy-dropyrindine (MPTP) and oxidative stress
-
Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, et al. (2005) Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahy-dropyrindine (MPTP) and oxidative stress. Proc Nad Acad Sci USA 102: 5215-5220.
-
(2005)
Proc Nad Acad Sci USA
, vol.102
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
-
12
-
-
67349264491
-
Involvement of ERK1/2 signaling pathway in DJ-1-induced neuroprotection against oxidative stress
-
Gu L, Cui T, Fan C, Zhao H, Zhao C, et al. (2009) Involvement of ERK1/2 signaling pathway in DJ-1-induced neuroprotection against oxidative stress. Biochem Biophys Res Commun 383: 469-474.
-
(2009)
Biochem Biophys Res Commun
, vol.383
, pp. 469-474
-
-
Gu, L.1
Cui, T.2
Fan, C.3
Zhao, H.4
Zhao, C.5
-
13
-
-
33748765225
-
PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model
-
Inden M, Taira T, Kitamura Y, Yanagida T, Tsuchiya D, et al. (2006) PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol Dis 24: 144-158.
-
(2006)
Neurobiol Dis
, vol.24
, pp. 144-158
-
-
Inden, M.1
Taira, T.2
Kitamura, Y.3
Yanagida, T.4
Tsuchiya, D.5
-
14
-
-
59849104963
-
DJ-1 protects against dopamine toxicity
-
Lev N, Ickowicz D, Barhum Y, Lev S, Melamed E, et al. (2009) DJ-1 protects against dopamine toxicity. J Neural Transm 116: 151-160.
-
(2009)
J Neural Transm
, vol.116
, pp. 151-160
-
-
Lev, N.1
Ickowicz, D.2
Barhum, Y.3
Lev, S.4
Melamed, E.5
-
15
-
-
1642527499
-
DJ-1 has a role in antioxidative stress to prevent cell death
-
Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K, et al. (2004) DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep 5: 213-218.
-
(2004)
EMBO Rep
, vol.5
, pp. 213-218
-
-
Taira, T.1
Saito, Y.2
Niki, T.3
Iguchi-Ariga, S.M.4
Takahashi, K.5
-
16
-
-
34548021452
-
Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits
-
Lavara-Culebras E, Parido N (2007) Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits. Gene 400: 158 -165.
-
(2007)
Gene
, vol.400
, pp. 158-165
-
-
Lavara-Culebras, E.1
Parido, N.2
-
17
-
-
13944279784
-
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary Parkinsonism
-
Martinat C, Shendelman S, Jonason A, Leete T, Beal MF, et al. (2004) Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES-derived cell model of primary Parkinsonism. PLoS Biol 2: e327.
-
(2004)
PLoS Biol
, vol.2
, pp. e327
-
-
Martinat, C.1
Shendelman, S.2
Jonason, A.3
Leete, T.4
Beal, M.F.5
-
18
-
-
77649266193
-
DJ-1 protects the nigrostriatal axis from the neuro toxin MPTP by modulation of the AKT pathway
-
Aleyasin H, Rousseaux MW, Marcogliese PC, Hewitt SJ, Irrcher I, et al. (2010) DJ-1 protects the nigrostriatal axis from the neuro toxin MPTP by modulation of the AKT pathway. Proc Nad Acad Sci USA 107: 3186 -3191.
-
(2010)
Proc Nad Acad Sci USA
, vol.107
, pp. 3186-3191
-
-
Aleyasin, H.1
Rousseaux, M.W.2
Marcogliese, P.C.3
Hewitt, S.J.4
Irrcher, I.5
-
19
-
-
36749013055
-
The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage
-
Aleyasin H, Rousseaux MW, Phillips M, Kim RH, Bland BJ, et al. (2007) The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage. Proc Nad Acad Sci U S A 104: 18748-18753.
-
(2007)
Proc Nad Acad Sci U S A
, vol.104
, pp. 18748-18753
-
-
Aleyasin, H.1
Rousseaux, M.W.2
Phillips, M.3
Kim, R.H.4
Bland, B.J.5
-
20
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles RM, Wilson MA, Miller DW, Ahmad R, McLendon C, et al. (2004) The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Nad Acad Sci U S A 101: 9103-9108.
-
(2004)
Proc Nad Acad Sci U S A
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
-
21
-
-
35548972027
-
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
-
Andres-Mateos E, Perier C, Zhang L, Blanchard-Fillion B, Greco TM, et al. (2007) DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc Natl Acad Sci USA 104: 14807-14812.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14807-14812
-
-
Andres-Mateos, E.1
Perier, C.2
Zhang, L.3
Blanchard-Fillion, B.4
Greco, T.M.5
-
22
-
-
33750052885
-
DJ-1, a cancer-and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
-
Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP (2006) DJ-1, a cancer-and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Nad Acad Sci USA 103: 15091-15096.
-
(2006)
Proc Nad Acad Sci USA
, vol.103
, pp. 15091-15096
-
-
Clements, C.M.1
McNally, R.S.2
Conti, B.J.3
Mak, T.W.4
Ting, J.P.5
-
23
-
-
77949550917
-
Keapl-Nrf2 activation in the presence and absence of DJ-1
-
Gan L, Johnson DA, Johnson JA (2010) Keapl-Nrf2 activation in the presence and absence of DJ-1. Eur J Neurosci 31: 967-977.
-
(2010)
Eur J Neurosci
, vol.31
, pp. 967-977
-
-
Gan, L.1
Johnson, D.A.2
Johnson, J.A.3
-
24
-
-
33947219266
-
Large-scale mapping of human protein-protein interactions by mass spectrometry
-
Ewing RM, Chu P, Elisma F, Li H, Taylor P, et al. (2007) Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol 3: 89.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 89
-
-
Ewing, R.M.1
Chu, P.2
Elisma, F.3
Li, H.4
Taylor, P.5
-
25
-
-
0035976903
-
Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein
-
Ng CJ, Wadleigh DJ, Gangopadhyay A, Hama S, Grijalva VR, et al. (2001) Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein. J Biol Chem 276: 44444-44449.
-
(2001)
J Biol Chem
, vol.276
, pp. 44444-44449
-
-
Ng, C.J.1
Wadleigh, D.J.2
Gangopadhyay, A.3
Hama, S.4
Grijalva, V.R.5
-
26
-
-
58949085858
-
Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis
-
Horke S, Witte I, Wilgenbus P, Altenhofer S, Kruger M, et al. (2008) Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis. Biochem J 416: 395-405.
-
(2008)
Biochem J
, vol.416
, pp. 395-405
-
-
Horke, S.1
Witte, I.2
Wilgenbus, P.3
Altenhofer, S.4
Kruger, M.5
-
27
-
-
78650869947
-
Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis
-
Devarajan A, Bourquard N, Hama S, Navab M, Grijalva VR, et al. (2011) Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal 14: 341-351.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 341-351
-
-
Devarajan, A.1
Bourquard, N.2
Hama, S.3
Navab, M.4
Grijalva, V.R.5
-
28
-
-
33749544927
-
Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: Anti-atherogenic role for paraoxonase-2
-
Ng CJ, Bourquard N, Grijalva V, Hama S, Shih DM, et al. (2006) Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2. J Biol Chem 281: 29491-29500.
-
(2006)
J Biol Chem
, vol.281
, pp. 29491-29500
-
-
Ng, C.J.1
Bourquard, N.2
Grijalva, V.3
Hama, S.4
Shih, D.M.5
-
29
-
-
0025864611
-
Paraoxonase prevents accumu lation of lipoperoxides in low-density lipoprotein
-
Mackness MI, Arrol S, Durrington PN (1991) Paraoxonase prevents accumu lation of lipoperoxides in low-density lipoprotein. FEBS Lett 286: 152-154.
-
(1991)
FEBS Lett
, vol.286
, pp. 152-154
-
-
Mackness, M.I.1
Arrol, S.2
Durrington, P.N.3
-
30
-
-
84903650130
-
Paraoxonase enzyme protects retinal pigment epithelium from chlorpyrifos insult
-
Jasna JM, Anandbabu K, Bharathi SR, Angayarkanni N (2014) Paraoxonase enzyme protects retinal pigment epithelium from chlorpyrifos insult. PLoS One 9: e101380.
-
(2014)
PLoS One
, vol.9
, pp. e101380
-
-
Jasna, J.M.1
Anandbabu, K.2
Bharathi, S.R.3
Angayarkanni, N.4
-
31
-
-
84901020481
-
Breaking the chain at the membrane: Paraoxonase 2 counteracts lipid peroxidation at the plasma membrane
-
Hagmann H, Kuczkowski A, Ruehl M, Lamkemeyer T, Brodesser S, et al. (2014) Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane. FASEBJ 28: 1769-1779.
-
(2014)
FASEBJ
, vol.28
, pp. 1769-1779
-
-
Hagmann, H.1
Kuczkowski, A.2
Ruehl, M.3
Lamkemeyer, T.4
Brodesser, S.5
-
33
-
-
33748678135
-
Paraoxonase gene polymorphisms and sporadic ALS
-
Slowik A, Tomik B, Wolkow PP, Partyka D, Turaj W, et al. (2006) Paraoxonase gene polymorphisms and sporadic ALS. Neurology 67: 766-770.
-
(2006)
Neurology
, vol.67
, pp. 766-770
-
-
Slowik, A.1
Tomik, B.2
Wolkow, P.P.3
Partyka, D.4
Turaj, W.5
-
34
-
-
33748707208
-
Paraoxonase cluster polymorphisms are associated with sporadic ALS
-
Saeed M, Siddique N, Hung WY, Usacheva E, Liu E, et al. (2006) Paraoxonase cluster polymorphisms are associated with sporadic ALS. Neurology 67: 771-776.
-
(2006)
Neurology
, vol.67
, pp. 771-776
-
-
Saeed, M.1
Siddique, N.2
Hung, W.Y.3
Usacheva, E.4
Liu, E.5
-
35
-
-
53749085916
-
Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden
-
Valdmanis PN, Kabashi E, Dyck A, Hince P, Lee J, et al. (2008) Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden. Neurology 71: 514-520.
-
(2008)
Neurology
, vol.71
, pp. 514-520
-
-
Valdmanis, P.N.1
Kabashi, E.2
Dyck, A.3
Hince, P.4
Lee, J.5
-
36
-
-
84901793865
-
Antioxidant defense enzyme genes and asthma susceptibility: Gender-specific effects and heterogeneity in gene-gene interactions between pathogenetic variants of the disease
-
Polonikov AV, Ivanov VP, Bogomazov AD, Freidin MB, Illig T, et al. (2014) Antioxidant defense enzyme genes and asthma susceptibility: gender-specific effects and heterogeneity in gene-gene interactions between pathogenetic variants of the disease. Biomed Res Int 2014: 708903.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 708903
-
-
Polonikov, A.V.1
Ivanov, V.P.2
Bogomazov, A.D.3
Freidin, M.B.4
Illig, T.5
-
37
-
-
9144263553
-
Possible association between Cys311Ser polymorphism of paraoxonase 2 gene and late-onset Alzheimer's disease in Chinese
-
Shi J, Zhang S, Tang M, Liu X, Li T, et al. (2004) Possible association between Cys311Ser polymorphism of paraoxonase 2 gene and late-onset Alzheimer's disease in Chinese. Brain Res Mol Brain Res 120: 201-204.
-
(2004)
Brain Res Mol Brain Res
, vol.120
, pp. 201-204
-
-
Shi, J.1
Zhang, S.2
Tang, M.3
Liu, X.4
Li, T.5
-
38
-
-
85047699586
-
Codon 311 (Cys → Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias
-
Janka Z, Juhasz A, Rimanoczy AA, Boda K, Marki-Zay J, et al. (2002) Codon 311 (Cys → Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias. Mol Psychiatry 7: 110-112.
-
(2002)
Mol Psychiatry
, vol.7
, pp. 110-112
-
-
Janka, Z.1
Juhasz, A.2
Rimanoczy, A.A.3
Boda, K.4
Marki-Zay, J.5
-
39
-
-
0035283113
-
Paraoxonase 1 Met-Leu 54 polymorphism is associated with Parkinson's disease
-
Akhmedova SN, Yakimovsky AK, Schwartz El (2001) Paraoxonase 1 Met-Leu 54 polymorphism is associated with Parkinson's disease. J Neurol Sci 184: 179 -182.
-
(2001)
J Neurol Sci
, vol.184
, pp. 179-182
-
-
Akhmedova, S.N.1
Yakimovsky, A.K.2
-
40
-
-
0036651220
-
Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease
-
Carmine A, Buervenich S, Sydow O, Anvret M, Olson L (2002) Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease. Mov Disord 17: 764-766.
-
(2002)
Mov Disord
, vol.17
, pp. 764-766
-
-
Carmine, A.1
Buervenich, S.2
Sydow, O.3
Anvret, M.4
Olson, L.5
-
41
-
-
72849117955
-
Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage
-
Zhang Y, Parsanejad M, Huang E, Qu D, Aleyasin H, et al. (2010) Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage. J Neurochem 112: 497-510.
-
(2010)
J Neurochem
, vol.112
, pp. 497-510
-
-
Zhang, Y.1
Parsanejad, M.2
Huang, E.3
Qu, D.4
Aleyasin, H.5
-
42
-
-
33748256674
-
The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin
-
Zhang Y, Qu D, Morris EJ, O'Hare MJ, Callaghan SM, et al. (2006) The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin. J Neurosci 26: 8819-8828.
-
(2006)
J Neurosci
, vol.26
, pp. 8819-8828
-
-
Zhang, Y.1
Qu, D.2
Morris, E.J.3
O'hare, M.J.4
Callaghan, S.M.5
-
43
-
-
0028012702
-
Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes
-
Pearson JP, Gray KM, Passador L, Tucker KD, Eberhard A, et al. (1994) Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc Natl Acad Sci USA 91: 197-201.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 197-201
-
-
Pearson, J.P.1
Gray, K.M.2
Passador, L.3
Tucker, K.D.4
Eberhard, A.5
-
45
-
-
76549126323
-
Pseudomonas signal molecule 3-oxo-C12-homoserine lactone interferes with binding of rosiglitazone to human PPAR gamma
-
Cooley MA, Whittall C, Rolph MS (2010) Pseudomonas signal molecule 3-oxo-C12-homoserine lactone interferes with binding of rosiglitazone to human PPAR gamma. Microbes Infect 12: 231-237.
-
(2010)
Microbes Infect
, vol.12
, pp. 231-237
-
-
Cooley, M.A.1
Whittall, C.2
Rolph, M.S.3
-
46
-
-
0028302588
-
Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa
-
Gray KM, Passador L, Iglewski BH, Greenberg EP (1994) Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa. J Bacteriol 176: 3076-3080.
-
(1994)
J Bacteriol
, vol.176
, pp. 3076-3080
-
-
Gray, K.M.1
Passador, L.2
Iglewski, B.H.3
Greenberg, E.P.4
-
47
-
-
36048994061
-
Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation
-
Shiner M, Fuhrman B, Aviram M (2007) Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation. Atherosclerosis 195: 313-321.
-
(2007)
Atherosclerosis
, vol.195
, pp. 313-321
-
-
Shiner, M.1
Fuhrman, B.2
Aviram, M.3
-
48
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, et al. (1998) A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 95: 2509-2514.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
-
49
-
-
33751093349
-
Adenovirus mediated expression of human paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein E-deficient mice
-
Ng CJ, Hama SY, Bourquard N, Navab M, Reddy ST (2006) Adenovirus mediated expression of human paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein E-deficient mice. Mol Genet Metab 89: 368 -373.
-
(2006)
Mol Genet Metab
, vol.89
, pp. 368-373
-
-
Ng, C.J.1
Hama, S.Y.2
Bourquard, N.3
Navab, M.4
Reddy, S.T.5
-
50
-
-
34250897267
-
Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease
-
Qu D, Rashidian J, Mount MP, Aleyasin H, Parsanejad M, et al. (2007) Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. Neuron 55: 37-52.
-
(2007)
Neuron
, vol.55
, pp. 37-52
-
-
Qu, D.1
Rashidian, J.2
Mount, M.P.3
Aleyasin, H.4
Parsanejad, M.5
-
51
-
-
77953121792
-
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death
-
Huang E, Qu D, Zhang Y, Venderova K, Haque ME, et al. (2010) The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nat Cell Biol 12: 563-571.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 563-571
-
-
Huang, E.1
Qu, D.2
Zhang, Y.3
Venderova, K.4
Haque, M.E.5
-
52
-
-
1642546640
-
Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage
-
Aleyasin H, Cregan SP, Iyirhiaro G, O'Hare MJ, Callaghan SM, et al. (2004) Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage. J Neurosci 24: 2963-2973.
-
(2004)
J Neurosci
, vol.24
, pp. 2963-2973
-
-
Aleyasin, H.1
Cregan, S.P.2
Iyirhiaro, G.3
O'hare, M.J.4
Callaghan, S.M.5
-
53
-
-
0037339957
-
Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress
-
Rosenblat M, Draganov D, Watson CE, Bisgaier CL, La Du BN, et al. (2003) Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress. Arterioscler Thromb Vase Biol 23: 468-474.
-
(2003)
Arterioscler Thromb Vase Biol
, vol.23
, pp. 468-474
-
-
Rosenblat, M.1
Draganov, D.2
Watson, C.E.3
Bisgaier, C.L.4
La Du, B.N.5
-
54
-
-
0029964357
-
MPP(+)-induced neurotoxicity in mouse is age-dependent: Evidenced by the selective inhibition of complexes of electron transport
-
Desai VG, Feuers RJ, Hart RW, Ali SF (1996) MPP(+)-induced neurotoxicity in mouse is age-dependent: evidenced by the selective inhibition of complexes of electron transport. Brain Res 715: 1-8.
-
(1996)
Brain Res
, vol.715
, pp. 1-8
-
-
Desai, V.G.1
Feuers, R.J.2
Hart, R.W.3
Ali, S.F.4
-
55
-
-
0023001744
-
Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-l,2,3,6-tetrahydropyridine, by mitochondria
-
Ramsay RR, Singer TP (1986) Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-l,2,3,6-tetrahydropyridine, by mitochondria. J Biol Chem 261: 7585-7587.
-
(1986)
J Biol Chem
, vol.261
, pp. 7585-7587
-
-
Ramsay, R.R.1
Singer, T.P.2
-
56
-
-
0023503459
-
The inhibition site of MPP+, the neurotoxic bioactivation product of l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase
-
Ramsay RR, Kowal AT, Johnson MK, Salach JI, Singer TP (1987) The inhibition site of MPP+, the neurotoxic bioactivation product of l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase. Arch Biochem Biophys 259: 645-649.
-
(1987)
Arch Biochem Biophys
, vol.259
, pp. 645-649
-
-
Ramsay, R.R.1
Kowal, A.T.2
Johnson, M.K.3
Salach, J.I.4
Singer, T.P.5
-
57
-
-
0022383666
-
A catalyst function for MPTP in superoxide formation
-
Poirier J, Barbeau A (1985) A catalyst function for MPTP in superoxide formation. Biochem Biophys Res Commun 131: 1284-1289.
-
(1985)
Biochem Biophys Res Commun
, vol.131
, pp. 1284-1289
-
-
Poirier, J.1
Barbeau, A.2
-
58
-
-
0022441893
-
Formation of superoxide and hydroxyl radicals from 1 -methyl-4-phenylpyridinium ion (MPP+): Reductive activation by NADPH cytochrome P-450 reductase
-
Sinha BK, Singh Y, Krishna G (1986) Formation of superoxide and hydroxyl radicals from 1 -methyl-4-phenylpyridinium ion (MPP+): reductive activation by NADPH cytochrome P-450 reductase. Biochem Biophys Res Commun 135: 583-588.
-
(1986)
Biochem Biophys Res Commun
, vol.135
, pp. 583-588
-
-
Sinha, B.K.1
Singh, Y.2
Krishna, G.3
-
59
-
-
8544227651
-
Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages
-
Shiner M, Fuhrman B, Aviram M (2004) Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages. Free Radic Biol Med 37: 2052-2063.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 2052-2063
-
-
Shiner, M.1
Fuhrman, B.2
Aviram, M.3
-
60
-
-
46249112510
-
Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone
-
Teiber JF, Horke S, Haines DC, Chowdhary PK, Xiao J, et al. (2008) Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone. Infect Immun 76: 2512-2519.
-
(2008)
Infect Immun
, vol.76
, pp. 2512-2519
-
-
Teiber, J.F.1
Horke, S.2
Haines, D.C.3
Chowdhary, P.K.4
Xiao, J.5
-
61
-
-
27744436315
-
Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing
-
Ozer FA, Pezzulo A, Shih DM, Chun C, Furlong C, et al. (2005) Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing. FFMS Microbiol Lett 253: 29-37.
-
(2005)
FFMS Microbiol Lett
, vol.253
, pp. 29-37
-
-
Ozer, F.A.1
Pezzulo, A.2
Shih, D.M.3
Chun, C.4
Furlong, C.5
-
62
-
-
21244473275
-
Quorum quenching enzyme activity is widely conserved in the sera of mammalian species
-
Yang F, Wang LH, Wang J, Dong YH, Hu JY, et al. (2005) Quorum quenching enzyme activity is widely conserved in the sera of mammalian species. FEBS Lett 579: 3713-3717.
-
(2005)
FEBS Lett
, vol.579
, pp. 3713-3717
-
-
Yang, F.1
Wang, L.H.2
Wang, J.3
Dong, Y.H.4
Hu, J.Y.5
-
63
-
-
77955516506
-
Lacto nases with organophosphatase activity: Structural and evolutionary perspectives
-
Draganov DI (2010) Lacto nases with organophosphatase activity: structural and evolutionary perspectives. Chem Biol Interact 187: 370-372.
-
(2010)
Chem Biol Interact
, vol.187
, pp. 370-372
-
-
Draganov, D.I.1
-
64
-
-
21244491480
-
Human paraoxonases (PON1, PON2, and PON 3) are lactonases with overlapping and distinct substrate specificities
-
Draganov DI, Teiber JF, Speelman A, Osawa Y, Sunahara R, et al. (2005) Human paraoxonases (PON1, PON2, and PON 3) are lactonases with overlapping and distinct substrate specificities. J Lipid Res 46: 1239-1247.
-
(2005)
J Lipid Res
, vol.46
, pp. 1239-1247
-
-
Draganov, D.I.1
Teiber, J.F.2
Speelman, A.3
Osawa, Y.4
Sunahara, R.5
-
65
-
-
78650815261
-
The three-gene paraoxonase family: Physiologic roles, actions and regulation
-
Precourt LP, Amre D, Denis MC, Lavoie JC, Delvin E, et al. (2011) The three-gene paraoxonase family: physiologic roles, actions and regulation. Atheroscle-rosis 214: 20-36.
-
(2011)
Atheroscle-rosis
, vol.214
, pp. 20-36
-
-
Precourt, L.P.1
Amre, D.2
Denis, M.C.3
Lavoie, J.C.4
Delvin, E.5
-
66
-
-
0038116507
-
Gene trap mutagenesis of hnRNP A2/B1: A cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene
-
Roshon M, DeGregori JV, Ruley HE (2003) Gene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene. BMC Genomics 4: 2.
-
(2003)
BMC Genomics
, vol.4
, pp. 2
-
-
Roshon, M.1
DeGregori, J.V.2
Ruley, H.E.3
-
67
-
-
48249145149
-
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways
-
van der Brug MP, Blackinton J, Chan dran J, Hao LY, Lal A, et al. (2008) RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci USA 105: 10244-10249.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10244-10249
-
-
Van Der Brug, M.P.1
Blackinton, J.2
Chandran, J.3
Hao, L.Y.4
Lal, A.5
-
68
-
-
0033103726
-
Identification and characterization of a novel protein that regulates RNA-protein interaction
-
Hod Y, Pentyala SN, Whyard TC, El-Maghrabi MR (1999) Identification and characterization of a novel protein that regulates RNA-protein interaction. J Cell Biochem 72: 435-444.
-
(1999)
J Cell Biochem
, vol.72
, pp. 435-444
-
-
Hod, Y.1
Pentyala, S.N.2
Whyard, T.C.3
El-Maghrabi, M.R.4
-
69
-
-
84894247749
-
Oxygen-glucose-deprived rat primary neural cells exhibit DJ-1 translocation into healthy mitochondria: A potent stroke therapeutic target
-
Kaneko Y, Tajiri N, Shojo H, Borlongan CV (2014) Oxygen-glucose-deprived rat primary neural cells exhibit DJ-1 translocation into healthy mitochondria: a potent stroke therapeutic target. CNS Neurosci Ther 20: 275-281.
-
(2014)
CNS Neurosci Ther
, vol.20
, pp. 275-281
-
-
Kaneko, Y.1
Tajiri, N.2
Shojo, H.3
Borlongan, C.V.4
-
70
-
-
10644244414
-
The paraoxonase gene family and atherosclerosis
-
Ng CJ, Shih DM, Hama SY, Villa N, Navab M, et al. (2005) The paraoxonase gene family and atherosclerosis. Free Radic Biol Med 38: 153-163.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 153-163
-
-
Ng, C.J.1
Shih, D.M.2
Hama, S.Y.3
Villa, N.4
Navab, M.5
-
71
-
-
84901781539
-
Regulation of the VHL/HIF-1 pathway by DJ-1
-
Parsanejad M, Zhang Y, Qu D, Irrcher I, Rousseaux MW, et al. (2014) Regulation of the VHL/HIF-1 pathway by DJ-1. J Neurosci 34: 8043-8050.
-
(2014)
J Neurosci
, vol.34
, pp. 8043-8050
-
-
Parsanejad, M.1
Zhang, Y.2
Qu, D.3
Irrcher, I.4
Rousseaux, M.W.5
-
72
-
-
72649095197
-
PINK1 polymorphism IVS1-7 A→G, exposure to environmental risk factors and anticipation of disease onset in Brazilian patients with early-onset Parkinson's Disease
-
Godeiro C Jr, Aguiar PM, Felicio AC, Barsottini OG, Silva SM, et al. (2010) PINK1 polymorphism IVS1-7 A→G, exposure to environmental risk factors and anticipation of disease onset in Brazilian patients with early-onset Parkinson's Disease. Neurosci Lett 469: 155-158.
-
(2010)
Neurosci Lett
, vol.469
, pp. 155-158
-
-
Godeiro, C.1
Aguiar, P.M.2
Felicio, A.C.3
Barsottini, O.G.4
Silva, S.M.5
-
73
-
-
79955557808
-
-
Environ Health Perspect
-
Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, et al. (2011) Rotenone, Paraquat and Parkinson's Disease. Environ Health Perspect.
-
(2011)
Rotenone, Paraquat and Parkinson's Disease.
-
-
Tanner, C.M.1
Kamel, F.2
Ross, G.W.3
Hoppin, J.A.4
Goldman, S.M.5
-
74
-
-
77957570725
-
Environmental and familial risk factors of Parkinsons disease: Case-control study
-
Sanyal J, Chakraborty DP, Sarkar B, Banerjee TK, Mukherjee SC, et al. (2010) Environmental and familial risk factors of Parkinsons disease: case-control study. Can J Neurol Sci 37: 637-642.
-
(2010)
Can J Neurol Sci
, vol.37
, pp. 637-642
-
-
Sanyal, J.1
Chakraborty, D.P.2
Sarkar, B.3
Banerjee, T.K.4
Mukherjee, S.C.5
-
75
-
-
0037708876
-
Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways
-
Saleh AM, Vijayasarathy C, Masoud L, Kumar L, Shahin A, et al. (2003) Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways. Toxicol Appl Pharmacol 190: 47-57.
-
(2003)
Toxicol Appl Pharmacol
, vol.190
, pp. 47-57
-
-
Saleh, A.M.1
Vijayasarathy, C.2
Masoud, L.3
Kumar, L.4
Shahin, A.5
-
76
-
-
33745089938
-
Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice
-
Ben-Shaul Y, Benmoyal-Segal L, Ben-Ari S, Bergman H, Soreq H (2006) Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice. Eur J Neurosci 23: 2915-2922.
-
(2006)
Eur J Neurosci
, vol.23
, pp. 2915-2922
-
-
Ben-Shaul, Y.1
Benmoyal-Segal, L.2
Ben-Ari, S.3
Bergman, H.4
Soreq, H.5
-
77
-
-
77955300136
-
One enzyme, two functions: PON2 prevents mitochondrial superoxide formation and apoptosis independent from its lactonase activity
-
Altenhofer S, Witte I, Teiber JF, Wilgenbus P, Pautz A, et al. (2010) One enzyme, two functions: PON2 prevents mitochondrial superoxide formation and apoptosis independent from its lactonase activity. J Biol Chem 285: 24398 -24403.
-
(2010)
J Biol Chem
, vol.285
, pp. 24398-24403
-
-
Altenhofer, S.1
Witte, I.2
Teiber, J.F.3
Wilgenbus, P.4
Pautz, A.5
-
78
-
-
63049138430
-
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
-
Junn E, Jang WH, Zhao X, Jeong BS, Mouradian MM (2009) Mitochondrial localization of DJ-1 leads to enhanced neuroprotection. J Neurosci Res 87: 123 -129.
-
(2009)
J Neurosci Res
, vol.87
, pp. 123-129
-
-
Junn, E.1
Jang, W.H.2
Zhao, X.3
Jeong, B.S.4
Mouradian, M.M.5
-
79
-
-
24944534660
-
Mitochondrial localization of the Parkinson's disease related protein DJ-1: Implications for pathogenesis
-
Zhang L, Shimoji M, Thomas B, Moore DJ, Yu SW, et al. (2005) Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Hum Mol Genet 14: 2063-2073.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2063-2073
-
-
Zhang, L.1
Shimoji, M.2
Thomas, B.3
Moore, D.J.4
Yu, S.W.5
-
80
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, et al. (2010) Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum Mol Genet 19: 3734-3746.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
|