PINK1 polymorphism IVS1-7 A → G, exposure to environmental risk factors and anticipation of disease onset in Brazilian patients with early-onset Parkinson's Disease

Neuroscience Letters

Volumn 469, Issue 1, 2010, Pages 155-158

  Godeiro Jr , Clecio ^a,b   de Carvalho Aguiar, Patricia M ^a,b   Felício, Andre C ^a,b   Barsottini, Orlando G P ^a,b   Silva, Sonia M A ^a   Borges, Vanderci ^a   Andrade, Luiz Augusto F ^b   Ferraz, Henrique Ballalai ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

Author keywords

Disease modifier; Early onset Parkinson's Disease; Environmental exposure; PINK1

Indexed keywords

ADENINE; DRINKING WATER; GUANINE; HERBICIDE; LEUCINE; ORGANIC SOLVENT; PARKIN; PARKIN 6; PESTICIDE; UNCLASSIFIED DRUG; VALINE; WELL WATER;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; BRAZIL; CIGARETTE SMOKING; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; FEMALE; GENETIC POLYMORPHISM; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARKINSON DISEASE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR; RURAL AREA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGE OF ONSET; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; PROTEIN KINASES; RISK ASSESSMENT; RISK FACTORS; WATER POLLUTION;

EID: 72649095197     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.11.064     Document Type: Article

References (15)

1. Aguiar P de C., Lessa P.S., Godeiro Jr. C., Barsottini O., Felício A.C., Borges V., Silva S.M., Saba R.A., Ferraz H.B., Moreira-Filho C.A., and Andrade L.A. Genetic and environmental findings in early-onset Parkinson's disease Brazilian patients. Mov. Disord. 23 (2008) 1228-1233
2. Clarimón J., Eerola J., Hellström O., Peuralinna T., Tienari P.J., and Singleton A.B. Assessment of PINK1 (PARK6) polymorphisms in Finnish PD. Neurobiol. Aging 27 (2006) 906-907
3. Elbaz A., Levecque C., Clavel J., Vidal J.S., Richard F., Amouyel P., Alpérovitch A., Chartier-Harlin M.C., and Tzourio C. CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease. Ann. Neurol. 55 (2004) 430-434
4. Gandhi S., Muqit M.M., Stanyer L., Healy D.G., Abou-Sleiman P.M., Hargreaves I., Heales S., Ganguly M., Parsons L., Lees A.J., Latchman D.S., Holton J.L., Wood N.W., and Revesz T. PINK1 protein in normal human brain and Parkinson's disease. Brain 129 (2006) 1720-1731
5. Ghione I., Di Fonzo A., Saladino F., Del Bo R., Bresolin N., Comi G.P., and Rango M. Parkin polymorphisms and environmental exposure: decrease in age at onset of Parkinson's disease. Neurotoxicology 28 (2007) 698-701
6. Godeiro C., de Carvalho Aguiar P.M., Felício A.C., Barsottini O.G., Silva S.M., Borges V., Andrade L.A., and Ferraz H.B. PINK1 mutations in a Brazilian cohort of early-onset Parkinson's disease patients. Mov. Disord. 24 (2009) 1693-1696
7. Klein C., and Schlossmacher M.G. Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder. Neurology 69 (2007) 2093-2104
8. Petit A., Kawarai T., Paitel E., Sanjo N., Maj M., Scheid M., Chen F., Gu Y., Hasegawa H., Salehi-Rad S., Wang L., Rogaeva E., Fraser P., Robinson B., St George-Hyslop P., and Tandon A. Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J. Biol. Chem. 280 (2005) 34025-34032
9. Priyadarshi A., Khuder S.A., Schaub E.A., and Priyadarshi S.S. Environmental risk factors and Parkinson's disease: a metanalysis. Environ. Res. 86 (2001) 122-127
10. Scheele C., Petrovic N., Faghihi M.A., Lassmann T., Fredriksson K., Rooyackers O., Wahlestedt C., Good L., and Timmons J.A. The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function. BMC Genomics 8 (2007) 74
11. Valente E.M., Brancati F., Caputo V., Graham E.A., Davis M.B., Ferraris A., Breteler M.M., Gasser T., Bonifati V., Bentivoglio A.R., De Michele G., Dürr A., Cortelli P., Filla A., Meco G., Oostra B.A., Brice A., Albanese A., Dallapiccola B., and Wood N.W. European consortium on genetic susceptibility in Parkinson's Disease, PARK6 is a common cause of familial Parkinsonism. Neurol. Sci. 23 (2002) S117-S118
12. Valente E.M., Salvi S., Ialongo T., Marongiu R., Elia A.E., Caputo V., Romito L., Albanese A., Dallapiccola B., and Bentivoglio A.R. PINK1 mutations are associated with sporadic early-onset Parkinsonism. Ann. Neurol. 56 (2004) 336-341
13. Valente E.M., Abou-Sleiman P.M., Caputo V., Muqit M.M., Harvey K., Gispert S., Ali Z., Del Turco D., Bentivoglio A.R., Healy D.G., Albanese A., Nussbaum R., González-Maldonado R., Deller T., Salvi S., Cortelli P., Gilks W.P., Latchman D.S., Harvey R.J., Dallapiccola B., Auburger G., and Wood N.W. Hereditary early-onset Parkinson's Disease caused by mutations ins PINK1. Science 304 (2004) 1158-11560
14. Wang F., Feng X., Ma J., Zou H., and Chan P. A common A340T variant in PINK1 gene associated with late-onset Parkinson's disease in Chinese. Neurosci. Lett. 410 (2006) 121-125
15. Warner T.T., and Schapira A.H. Genetic and environmental factors in the cause of Parkinson's disease. Ann. Neurol. 53 (2003) S16-S23