-
1
-
-
2942684871
-
The parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles RM, Wilson MA, Miller DW, et al. The parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci U S A 2004;101:9103-9108.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
-
2
-
-
0242363670
-
Molecular pathways of neurodegeneration in parkinson's disease
-
Dawson TM, Dawson VL. Molecular pathways of neurodegeneration in parkinson's disease. Science 2003;302:819-822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
3
-
-
33750052885
-
DJ-1, a cancer- and parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
-
Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP. DJ-1, a cancer- and parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci U S A 2006;103:15091-15096.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15091-15096
-
-
Clements, C.M.1
McNally, R.S.2
Conti, B.J.3
Mak, T.W.4
Ting, J.P.5
-
4
-
-
40849138195
-
DJ-1 decreases Bax expression through repressing p53 transcriptional activity
-
Fan J, Ren H, Jia N, et al. DJ-1 decreases Bax expression through repressing p53 transcriptional activity. J Biol Chem 2008;283:4022-4030.
-
(2008)
J Biol Chem
, vol.283
, pp. 4022-4030
-
-
Fan, J.1
Ren, H.2
Jia, N.3
-
5
-
-
34250361915
-
Structural determinants of the c-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1
-
Gorner K, Holtorf E, Waak J, et al. Structural determinants of the c-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1. J Biol Chem 2007;282:13680-13691.
-
(2007)
J Biol Chem
, vol.282
, pp. 13680-13691
-
-
Gorner, K.1
Holtorf, E.2
Waak, J.3
-
6
-
-
22144465488
-
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
-
Junn E, Taniguchi H, Jeong BS, Zhao X, Ichijo H, Mouradian MM. Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci U S A 2005;102:9691-9696.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9691-9696
-
-
Junn, E.1
Taniguchi, H.2
Jeong, B.S.3
Zhao, X.4
Ichijo, H.5
Mouradian, M.M.6
-
7
-
-
26444489693
-
Inactivation of drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
-
Yang Y, Gehrke S, Haque ME, et al. Inactivation of drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A 2005;102:13670-13675.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13670-13675
-
-
Yang, Y.1
Gehrke, S.2
Haque, M.E.3
-
8
-
-
46749086971
-
DJ-1, a causative gene product of a familial form of parkinson's disease, is secreted through microdomains
-
Tsuboi Y, Munemoto H, Ishikawa S, Matsumoto K, Iguchi-Ariga SM, Ariga H. DJ-1, a causative gene product of a familial form of parkinson's disease, is secreted through microdomains. FEBS Lett 2008;582:2643-2649.
-
(2008)
FEBS Lett
, vol.582
, pp. 2643-2649
-
-
Tsuboi, Y.1
Munemoto, H.2
Ishikawa, S.3
Matsumoto, K.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
9
-
-
68849097924
-
Regulation of astrocyte inflammatory responses by the parkinson's disease-associated gene DJ-1
-
Waak J, Weber SS, Waldenmaier A, et al. Regulation of astrocyte inflammatory responses by the parkinson's disease-associated gene DJ-1. FASEB J 2009;23:2478-2489.
-
(2009)
FASEB J
, vol.23
, pp. 2478-2489
-
-
Waak, J.1
Weber, S.S.2
Waldenmaier, A.3
-
10
-
-
77950611718
-
Menstrual blood cells display stem cell-like phenotypic markers and exert neuroprotection following transplantation in experimental stroke
-
Borlongan CV, Kaneko Y, Maki M, et al. Menstrual blood cells display stem cell-like phenotypic markers and exert neuroprotection following transplantation in experimental stroke. Stem Cells Dev 2010;19:439-452.
-
(2010)
Stem Cells Dev
, vol.19
, pp. 439-452
-
-
Borlongan, C.V.1
Kaneko, Y.2
Maki, M.3
-
11
-
-
65049089113
-
Regulation of glutathione synthesis
-
Lu SC. Regulation of glutathione synthesis. Mol Aspects Med 2009;30:42-59.
-
(2009)
Mol Aspects Med
, vol.30
, pp. 42-59
-
-
Lu, S.C.1
-
12
-
-
84857986212
-
Serum DJ-1/PARK 7 is a potential biomarker of choroidal nevi transformation
-
Bande MF, Santiago M, Blanco MJ, et al. Serum DJ-1/PARK 7 is a potential biomarker of choroidal nevi transformation. Invest Ophthalmol Vis Sci 2012;53:62-67.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 62-67
-
-
Bande, M.F.1
Santiago, M.2
Blanco, M.J.3
-
13
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008;183:795-803.
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
14
-
-
77952292943
-
Dynamic movements of Ro52 cytoplasmic bodies along microtubules
-
Tanaka M, Tanji K, Niida M, Kamitani T. Dynamic movements of Ro52 cytoplasmic bodies along microtubules. Histochem Cell Biol 2010;133:273-284.
-
(2010)
Histochem Cell Biol
, vol.133
, pp. 273-284
-
-
Tanaka, M.1
Tanji, K.2
Niida, M.3
Kamitani, T.4
-
15
-
-
84884943120
-
DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway
-
Kaneko Y, Shojo H, Burns J, Staples M, Tajiri N, Borlongan CV. DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway. Neurobiol Dis 2013;62C:56-61.
-
(2013)
Neurobiol Dis
, vol.62 C
, pp. 56-61
-
-
Kaneko, Y.1
Shojo, H.2
Burns, J.3
Staples, M.4
Tajiri, N.5
Borlongan, C.V.6
-
16
-
-
84885178135
-
Edaravone prevents neurotoxicity of mutant l166p DJ-1 in parkinson's disease
-
Li B, Yu D, Xu Z. Edaravone prevents neurotoxicity of mutant l166p DJ-1 in parkinson's disease. J Mol Neurosci 2013;51:539-549.
-
(2013)
J Mol Neurosci
, vol.51
, pp. 539-549
-
-
Li, B.1
Yu, D.2
Xu, Z.3
-
17
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
-
Thomas KJ, McCoy MK, Blackinton J, et al. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum Mol Genet 2011;20:40-50.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
-
18
-
-
0035187302
-
Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer
-
Le Naour F, Misek DE, Krause MC, et al. Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer. Clin Cancer Res 2001;7:3328-3335.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3328-3335
-
-
Le Naour, F.1
Misek, D.E.2
Krause, M.C.3
-
19
-
-
0036606009
-
Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles
-
Miura K, Bowman ED, Simon R, et al. Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles. Cancer Res 2002;62:3244-3250.
-
(2002)
Cancer Res
, vol.62
, pp. 3244-3250
-
-
Miura, K.1
Bowman, E.D.2
Simon, R.3
-
20
-
-
77956896275
-
DJ-1, an oncogene and causative gene for familial parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up-regulation of c-Myc
-
Kim YC, Kitaura H, Iguchi-Ariga SM, Ariga H. DJ-1, an oncogene and causative gene for familial parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up-regulation of c-Myc. FEBS Lett 2010;584:3891-3895.
-
(2010)
FEBS Lett
, vol.584
, pp. 3891-3895
-
-
Kim, Y.C.1
Kitaura, H.2
Iguchi-Ariga, S.M.3
Ariga, H.4
-
21
-
-
78650719636
-
Amyloid-beta triggers the release of neuronal hexokinase 1 from mitochondria
-
Saraiva LM, Seixas da Silva GS, Galina A, et al. Amyloid-beta triggers the release of neuronal hexokinase 1 from mitochondria. PLoS One 2010;5:e15230.
-
(2010)
PLoS One
, vol.5
-
-
Saraiva, L.M.1
Seixas da Silva, G.S.2
Galina, A.3
-
22
-
-
77956319634
-
Calcium-dependent mitochondrial function and dysfunction in neurons
-
Pivovarova NB, Andrews SB. Calcium-dependent mitochondrial function and dysfunction in neurons. FEBS J 2010;277:3622-3636.
-
(2010)
FEBS J
, vol.277
, pp. 3622-3636
-
-
Pivovarova, N.B.1
Andrews, S.B.2
-
23
-
-
73449139060
-
Severe blood-brain barrier disruption and surrounding tissue injury
-
Chen B, Friedman B, Cheng Q, et al. Severe blood-brain barrier disruption and surrounding tissue injury. Stroke 2009;40:e666-e674.
-
(2009)
Stroke
, vol.40
-
-
Chen, B.1
Friedman, B.2
Cheng, Q.3
-
24
-
-
76649108526
-
Complement component c1q mediates mitochondria-driven oxidative stress in neonatal hypoxic-ischemic brain injury
-
Ten VS, Yao J, Ratner V, et al. Complement component c1q mediates mitochondria-driven oxidative stress in neonatal hypoxic-ischemic brain injury. J Neurosci 2010;30:2077-2087.
-
(2010)
J Neurosci
, vol.30
, pp. 2077-2087
-
-
Ten, V.S.1
Yao, J.2
Ratner, V.3
-
25
-
-
40449098332
-
RNA suppression of ERK2 leads to collapse of mitochondrial membrane potential with acute oxidative stress in human lens epithelial cells
-
Flynn JM, Lannigan DA, Clark DE, Garner MH, Cammarata PR. RNA suppression of ERK2 leads to collapse of mitochondrial membrane potential with acute oxidative stress in human lens epithelial cells. Am J Physiol Endocrinol Metab 2008;294:E589-E599.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Flynn, J.M.1
Lannigan, D.A.2
Clark, D.E.3
Garner, M.H.4
Cammarata, P.R.5
-
26
-
-
48749098849
-
The mitochondrial permeability transition, and oxidative and nitrosative stress in the mechanism of copper toxicity in cultured neurons and astrocytes
-
Reddy PV, Rao KV, Norenberg MD. The mitochondrial permeability transition, and oxidative and nitrosative stress in the mechanism of copper toxicity in cultured neurons and astrocytes. Lab Invest 2008;88:816-830.
-
(2008)
Lab Invest
, vol.88
, pp. 816-830
-
-
Reddy, P.V.1
Rao, K.V.2
Norenberg, M.D.3
-
27
-
-
33745684904
-
Mitochondrial ros-induced ros release: An update and review
-
Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial ros-induced ros release: An update and review. Biochim Biophys Acta 2006;1757:509-517.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 509-517
-
-
Zorov, D.B.1
Juhaszova, M.2
Sollott, S.J.3
-
28
-
-
1642527499
-
DJ-1 has a role in antioxidative stress to prevent cell death
-
Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K, Ariga H. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep 2004;5:213-218.
-
(2004)
EMBO Rep
, vol.5
, pp. 213-218
-
-
Taira, T.1
Saito, Y.2
Niki, T.3
Iguchi-Ariga, S.M.4
Takahashi, K.5
Ariga, H.6
-
29
-
-
77953316340
-
Parkinson disease-associated DJ-1 is required for the expression of the glial cell line-derived neurotrophic factor receptor RET in human neuroblastoma cells
-
Foti R, Zucchelli S, Biagioli M, et al. Parkinson disease-associated DJ-1 is required for the expression of the glial cell line-derived neurotrophic factor receptor RET in human neuroblastoma cells. J Biol Chem 2010;285:18565-18574.
-
(2010)
J Biol Chem
, vol.285
, pp. 18565-18574
-
-
Foti, R.1
Zucchelli, S.2
Biagioli, M.3
-
30
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E. Autophagy and metabolism. Science 2010;330:1344-1348.
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
31
-
-
33748028841
-
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related gtpases in neurons
-
Barsoum MJ, Yuan H, Gerencser AA, et al. Nitric oxide-induced mitochondrial fission is regulated by dynamin-related gtpases in neurons. EMBO J 2006;25:3900-3911.
-
(2006)
EMBO J
, vol.25
, pp. 3900-3911
-
-
Barsoum, M.J.1
Yuan, H.2
Gerencser, A.A.3
-
32
-
-
33745742159
-
Mitochondrial fission and apoptosis: An ongoing trial
-
Parone PA, Martinou JC. Mitochondrial fission and apoptosis: An ongoing trial. Biochim Biophys Acta 2006;1763:522-530.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 522-530
-
-
Parone, P.A.1
Martinou, J.C.2
-
33
-
-
77953139108
-
Increased nuclear apoptosis-inducing factor after transient focal ischemia: A 12/15-lipoxygenase-dependent organelle damage pathway
-
Pallast S, Arai K, Pekcec A, et al. Increased nuclear apoptosis-inducing factor after transient focal ischemia: A 12/15-lipoxygenase-dependent organelle damage pathway. J Cereb Blood Flow Metab 2010;30:1157-1167.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 1157-1167
-
-
Pallast, S.1
Arai, K.2
Pekcec, A.3
-
36
-
-
55749098984
-
2+-dependent glutamate release from rat cortical astrocytes
-
2+-dependent glutamate release from rat cortical astrocytes. J Neurosci 2008;28:9682-9691.
-
(2008)
J Neurosci
, vol.28
, pp. 9682-9691
-
-
Reyes, R.C.1
Parpura, V.2
-
37
-
-
77949623516
-
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of parkinson's disease-associated protein DJ-1
-
Krebiehl G, Ruckerbauer S, Burbulla LF, et al. Reduced basal autophagy and impaired mitochondrial dynamics due to loss of parkinson's disease-associated protein DJ-1. PLoS One 2010;5:e9367.
-
(2010)
PLoS One
, vol.5
-
-
Krebiehl, G.1
Ruckerbauer, S.2
Burbulla, L.F.3
-
38
-
-
0033936321
-
Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia
-
Borlongan CV, Yamamoto M, Takei N, et al. Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia. FASEB J 2000;14:1307-1317.
-
(2000)
FASEB J
, vol.14
, pp. 1307-1317
-
-
Borlongan, C.V.1
Yamamoto, M.2
Takei, N.3
-
39
-
-
0027328680
-
Combined oxygen and glucose deprivation in cortical cell culture: Calcium-dependent and calcium-independent mechanisms of neuronal injury
-
Goldberg MP, Choi DW. Combined oxygen and glucose deprivation in cortical cell culture: Calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosci 1993;13:3510-3524.
-
(1993)
J Neurosci
, vol.13
, pp. 3510-3524
-
-
Goldberg, M.P.1
Choi, D.W.2
-
40
-
-
65649118917
-
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
-
Xiong H, Wang D, Chen L, et al. Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J Clin Invest 2009;119:650-660.
-
(2009)
J Clin Invest
, vol.119
, pp. 650-660
-
-
Xiong, H.1
Wang, D.2
Chen, L.3
-
41
-
-
63549149703
-
Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast
-
Leadsham JE, Miller K, Ayscough KR, et al. Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast. J Cell Sci 2009;122:706-715.
-
(2009)
J Cell Sci
, vol.122
, pp. 706-715
-
-
Leadsham, J.E.1
Miller, K.2
Ayscough, K.R.3
-
42
-
-
78650987611
-
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission
-
Mears JA, Lackner LL, Fang S, Ingerman E, Nunnari J, Hinshaw JE. Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission. Nat Struct Mol Biol 2011;18:20-26.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 20-26
-
-
Mears, J.A.1
Lackner, L.L.2
Fang, S.3
Ingerman, E.4
Nunnari, J.5
Hinshaw, J.E.6
-
43
-
-
36749013055
-
The parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage
-
Aleyasin H, Rousseaux MW, Phillips M, et al. The parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage. Proc Natl Acad Sci U S A 2007;104:18748-18753.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 18748-18753
-
-
Aleyasin, H.1
Rousseaux, M.W.2
Phillips, M.3
-
44
-
-
39749124831
-
DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats
-
Yanagisawa D, Kitamura Y, Inden M, et al. DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats. J Cereb Blood Flow Metab 2008;28:563-578.
-
(2008)
J Cereb Blood Flow Metab
, vol.28
, pp. 563-578
-
-
Yanagisawa, D.1
Kitamura, Y.2
Inden, M.3
-
45
-
-
62749199149
-
DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age
-
Mullett SJ, Hamilton RL, Hinkle DA. DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age. Neuropathology 2009;29:125-131.
-
(2009)
Neuropathology
, vol.29
, pp. 125-131
-
-
Mullett, S.J.1
Hamilton, R.L.2
Hinkle, D.A.3
-
46
-
-
77951756407
-
Pro-survival role for parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons
-
Aron L, Klein P, Pham TT, Kramer ER, Wurst W, Klein R. Pro-survival role for parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biol 2010;8:e1000349.
-
(2010)
PLoS Biol
, vol.8
-
-
Aron, L.1
Klein, P.2
Pham, T.T.3
Kramer, E.R.4
Wurst, W.5
Klein, R.6
-
47
-
-
59049105937
-
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses
-
Vasseur S, Afzal S, Tardivel-Lacombe J, Park DS, Iovanna JL, Mak TW. DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses. Proc Natl Acad Sci U S A 2009;106:1111-1116.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1111-1116
-
-
Vasseur, S.1
Afzal, S.2
Tardivel-Lacombe, J.3
Park, D.S.4
Iovanna, J.L.5
Mak, T.W.6
-
48
-
-
75149118479
-
Expression of the parkinson's disease-related protein DJ-1 during neural stem cell proliferation
-
Yan H, Pu XP. Expression of the parkinson's disease-related protein DJ-1 during neural stem cell proliferation. Biol Pharm Bull 2010;33:18-21.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 18-21
-
-
Yan, H.1
Pu, X.P.2
|