-
1
-
-
84872639802
-
An enzyme in animal tissues capable of hydrolyzing the phosphorus-fluoride bond of alkyl fluorophosphates
-
Mazur A. An enzyme in animal tissues capable of hydrolyzing the phosphorus-fluoride bond of alkyl fluorophosphates. J. Biol. Chem. 1946, 164:271-289.
-
(1946)
J. Biol. Chem.
, vol.164
, pp. 271-289
-
-
Mazur, A.1
-
2
-
-
70350567023
-
Serum esterases. II. An enzyme hydrolysing diethyl p-nitrophenyl acetate (E600) and its identity with A-esterase of mammalian sera
-
Aldridge W.N. Serum esterases. II. An enzyme hydrolysing diethyl p-nitrophenyl acetate (E600) and its identity with A-esterase of mammalian sera. Biochem. J. 1953, 53:117-124.
-
(1953)
Biochem. J.
, vol.53
, pp. 117-124
-
-
Aldridge, W.N.1
-
4
-
-
0030293198
-
The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
-
Davies H.G., Richter R.J., Keifer M., Broomfield C.A., Sowalla J., Furlong C.E. The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nat. Genet. 1996, 14:334-336.
-
(1996)
Nat. Genet.
, vol.14
, pp. 334-336
-
-
Davies, H.G.1
Richter, R.J.2
Keifer, M.3
Broomfield, C.A.4
Sowalla, J.5
Furlong, C.E.6
-
5
-
-
0033783020
-
Human serum paraoxonase (PON1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters
-
Billecke S., Draganov D., Counsell R., Stetson P., Watson C., Hsu C., La Du B.N. Human serum paraoxonase (PON1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters. Drug Metab. Dispos. 2000, 28:1335-1342.
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 1335-1342
-
-
Billecke, S.1
Draganov, D.2
Counsell, R.3
Stetson, P.4
Watson, C.5
Hsu, C.6
La Du, B.N.7
-
6
-
-
33645819801
-
Senescence marker protein 30 functions as gluconolactonase in l-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy
-
Kondo Y., Inai Y., Sato Y., Handa S., Kubo S., Shimokado K., Goto S., Nishikimi M., Maruyama N., Ishigami A. Senescence marker protein 30 functions as gluconolactonase in l-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:5723-5728.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 5723-5728
-
-
Kondo, Y.1
Inai, Y.2
Sato, Y.3
Handa, S.4
Kubo, S.5
Shimokado, K.6
Goto, S.7
Nishikimi, M.8
Maruyama, N.9
Ishigami, A.10
-
7
-
-
25444456889
-
Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily
-
Roodveldt C., Tawfik D.S. Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily. Biochemistry 2005, 44:12728-12736.
-
(2005)
Biochemistry
, vol.44
, pp. 12728-12736
-
-
Roodveldt, C.1
Tawfik, D.S.2
-
8
-
-
33751221972
-
The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase
-
Afriat L., Roodveldt C., Manco G., Tawfik D.S. The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase. Biochemistry 2006, 45:13677-13686.
-
(2006)
Biochemistry
, vol.45
, pp. 13677-13686
-
-
Afriat, L.1
Roodveldt, C.2
Manco, G.3
Tawfik, D.S.4
-
9
-
-
0029937118
-
The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family
-
Primo-Parmo S.L., Sorenson R.C., Teiber J., La Du B.N. The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. Genomics 1996, 33:498-507.
-
(1996)
Genomics
, vol.33
, pp. 498-507
-
-
Primo-Parmo, S.L.1
Sorenson, R.C.2
Teiber, J.3
La Du, B.N.4
-
11
-
-
21244491480
-
Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities
-
Draganov D.I., Teiber J.F., Speelman A., Osawa Y., Sunahara R., La Du B.N. Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. J. Lipid Res. 2005, 46:1239-1247.
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1239-1247
-
-
Draganov, D.I.1
Teiber, J.F.2
Speelman, A.3
Osawa, Y.4
Sunahara, R.5
La Du, B.N.6
-
12
-
-
0042261695
-
Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3
-
Teiber J.F., Draganov D.I., La Du B.N. Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3. Biochem. Pharmacol. 2003, 66:887-896.
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 887-896
-
-
Teiber, J.F.1
Draganov, D.I.2
La Du, B.N.3
-
13
-
-
77955518309
-
PONs' natural substrates-the key to their physiological roles
-
Springer, Dordrecht, B. Mackness, M. Mackness, M. Aviram, G. Paragh (Eds.)
-
Draganov D.I., Teiber J.F. PONs' natural substrates-the key to their physiological roles. The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism 2008, 297-306. Springer, Dordrecht. B. Mackness, M. Mackness, M. Aviram, G. Paragh (Eds.).
-
(2008)
The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism
, pp. 297-306
-
-
Draganov, D.I.1
Teiber, J.F.2
-
14
-
-
0034721761
-
Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation
-
Draganov D.I., Stetson P.L., Watson C.E., Billecke S.S., La Du B.N. Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation. J. Biol. Chem. 2000, 275:33435-33442.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33435-33442
-
-
Draganov, D.I.1
Stetson, P.L.2
Watson, C.E.3
Billecke, S.S.4
La Du, B.N.5
-
15
-
-
11244281311
-
The 'evolvability' of promiscuous protein functions
-
Aharoni A.L., Gaidukov O., Khersonsky S., Gold McQ., Roodveldt C., Tawfik D.S. The 'evolvability' of promiscuous protein functions. Nat. Genet. 2005, 37:73-76.
-
(2005)
Nat. Genet.
, vol.37
, pp. 73-76
-
-
Aharoni, A.L.1
Gaidukov, O.2
Khersonsky, S.3
Gold, M.4
Roodveldt, C.5
Tawfik, D.S.6
-
16
-
-
17644367506
-
Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase
-
Khersonsky O., Tawfik D.S. Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase. Biochemistry 2005, 44:6371-6382.
-
(2005)
Biochemistry
, vol.44
, pp. 6371-6382
-
-
Khersonsky, O.1
Tawfik, D.S.2
-
17
-
-
2342569704
-
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes
-
Harel M., Aharoni A., Gaidukov L., Brumshtein B., Khersonsky O., Meged R., Dvir H., Ravelli R.B., McCarthy A., Toker L., Silman I., Sussman J.L., Tawfik D.S. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes. Nat. Struct. Mol. Biol. 2004, 11:412-419.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 412-419
-
-
Harel, M.1
Aharoni, A.2
Gaidukov, L.3
Brumshtein, B.4
Khersonsky, O.5
Meged, R.6
Dvir, H.7
Ravelli, R.B.8
McCarthy, A.9
Toker, L.10
Silman, I.11
Sussman, J.L.12
Tawfik, D.S.13
-
18
-
-
33646373929
-
The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases
-
Khersonsky O., Tawfik D.S. The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases. J. Biol. Chem. 2006, 281:7649-7656.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 7649-7656
-
-
Khersonsky, O.1
Tawfik, D.S.2
-
19
-
-
18444379944
-
Analysis of active-site amino-acid residues of human serum paraoxonase using competitive substrates
-
Yeung D.T., Lenz D.E., Cerasoli D.M. Analysis of active-site amino-acid residues of human serum paraoxonase using competitive substrates. FEBS J. 2005, 272:2225-2230.
-
(2005)
FEBS J.
, vol.272
, pp. 2225-2230
-
-
Yeung, D.T.1
Lenz, D.E.2
Cerasoli, D.M.3
-
20
-
-
70350513002
-
Dramatic differences in organophosphorus hydrolase activity between human and chimeric recombinant mammalian paraoxonase-1 enzymes
-
Otto T.C., Harsch C.K., Yeung D.T., Magliery T.J., Cerasoli D.M., Lenz D.E. Dramatic differences in organophosphorus hydrolase activity between human and chimeric recombinant mammalian paraoxonase-1 enzymes. Biochemistry 2009, 48:10416-10422.
-
(2009)
Biochemistry
, vol.48
, pp. 10416-10422
-
-
Otto, T.C.1
Harsch, C.K.2
Yeung, D.T.3
Magliery, T.J.4
Cerasoli, D.M.5
Lenz, D.E.6
-
21
-
-
77955509686
-
Paraoxonase 1 (PON1) as a potential catalytic scavenger in the prophylaxis and treatment of organophosphate poisoning
-
Publishing House of the Union of Scientist in Bulgaria, Sofia, A. Monov, C. Dishovski (Eds.)
-
Draganov D. Paraoxonase 1 (PON1) as a potential catalytic scavenger in the prophylaxis and treatment of organophosphate poisoning. Medical Aspects of Chemical and Biological Terrorism-Chemical Terrorism and Traumatism 2005, 227-246. Publishing House of the Union of Scientist in Bulgaria, Sofia. A. Monov, C. Dishovski (Eds.).
-
(2005)
Medical Aspects of Chemical and Biological Terrorism-Chemical Terrorism and Traumatism
, pp. 227-246
-
-
Draganov, D.1
-
22
-
-
61649102440
-
Human paraoxonase 1: a potential bioscavenger of oraganophosphorus nerve agents
-
Springer, Dordrecht, B. Mackness, M. Mackness, M. Aviram, G. Paragh (Eds.)
-
Yeung D.T., Lenz D.E., Cerasoli D.M. Human paraoxonase 1: a potential bioscavenger of oraganophosphorus nerve agents. The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism 2008, 151-170. Springer, Dordrecht. B. Mackness, M. Mackness, M. Aviram, G. Paragh (Eds.).
-
(2008)
The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism
, pp. 151-170
-
-
Yeung, D.T.1
Lenz, D.E.2
Cerasoli, D.M.3
-
23
-
-
0024501160
-
Partial characterization of an enzyme that hydrolyzes sarin, soman, tabun, and diisopropyl phosphorofluoridate (DFP)
-
Little J.S., Broomfield C.A., Fox-Talbot M.K., Boucher L.J., MacIver B., Lenz D.E. Partial characterization of an enzyme that hydrolyzes sarin, soman, tabun, and diisopropyl phosphorofluoridate (DFP). Biochem. Pharmacol. 1989, 38:23-29.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 23-29
-
-
Little, J.S.1
Broomfield, C.A.2
Fox-Talbot, M.K.3
Boucher, L.J.4
MacIver, B.5
Lenz, D.E.6
-
24
-
-
17644438047
-
Characterization of a soluble mouse liver enzyme capable of hydrolyzing diisopropyl phosphorofluoridate
-
Billecke S.S., Primo-Parmo S.L., Dunlop C.S., Doorn J.A., La Du B.N., Broomfield C.A. Characterization of a soluble mouse liver enzyme capable of hydrolyzing diisopropyl phosphorofluoridate. Chemico-Biol. Interact. 1999, 119-120:251-256.
-
(1999)
Chemico-Biol. Interact.
, pp. 251-256
-
-
Billecke, S.S.1
Primo-Parmo, S.L.2
Dunlop, C.S.3
Doorn, J.A.4
La Du, B.N.5
Broomfield, C.A.6
-
25
-
-
3142604667
-
Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver
-
Kondo Y., Ishigami A., Kubo S., Handa S., Gomi K., Hirokawa K., Kajiyama N., Chiba T., Shimokado K., Maruyama N. Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver. FEBS Lett. 2004, 570:57-62.
-
(2004)
FEBS Lett.
, vol.570
, pp. 57-62
-
-
Kondo, Y.1
Ishigami, A.2
Kubo, S.3
Handa, S.4
Gomi, K.5
Hirokawa, K.6
Kajiyama, N.7
Chiba, T.8
Shimokado, K.9
Maruyama, N.10
-
26
-
-
84954358029
-
The first crystal structure of gluconolactonase important in the glucose secondary metabolic pathways
-
Chen C.-N., Chin K.-H., Wang A.H.-J., Chou S.-H. The first crystal structure of gluconolactonase important in the glucose secondary metabolic pathways. J. Mol. Biol. 2008, 384:604-614.
-
(2008)
J. Mol. Biol.
, vol.384
, pp. 604-614
-
-
Chen, C.-N.1
Chin, K.-H.2
Wang, A.H.-J.3
Chou, S.-H.4
-
27
-
-
77955516004
-
-
di Targiany, et al., this volume.
-
di Targiany, et al., this volume.
-
-
-
-
29
-
-
44449170433
-
Structural basis for natural lactonase and promiscuous phosphotriesterase activities
-
Elias M., Dupuy J., Merone L., Mandrich L., Porzio E., Moniot S., Rochu D., Lecomte C., Rossi M., Masson P., Manco G., Chabriere E. Structural basis for natural lactonase and promiscuous phosphotriesterase activities. J. Mol. Biol. 2008, 379:1017-1028.
-
(2008)
J. Mol. Biol.
, vol.379
, pp. 1017-1028
-
-
Elias, M.1
Dupuy, J.2
Merone, L.3
Mandrich, L.4
Porzio, E.5
Moniot, S.6
Rochu, D.7
Lecomte, C.8
Rossi, M.9
Masson, P.10
Manco, G.11
Chabriere, E.12
-
31
-
-
0036226347
-
Novel sequences propel familiar folds
-
Jawad Z., Paoli M. Novel sequences propel familiar folds. Structure 2002, 10:447-454.
-
(2002)
Structure
, vol.10
, pp. 447-454
-
-
Jawad, Z.1
Paoli, M.2
|