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Volumn 34, Issue 4, 2014, Pages 1159-1168

Sirt3 attenuates hydrogen peroxide-induced oxidative stress through the preservation of mitochondrial function in HT22 cells

Author keywords

Mitochondria; Oxidative stress; Reactive oxygen species; Sirt3

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CASPASE 3; CASPASE 9; CYTOCHROME C; HYDROGEN PEROXIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SIRTUIN 3; SMALL INTERFERING RNA; SIRT3 PROTEIN, MOUSE;

EID: 84907466059     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1876     Document Type: Article
Times cited : (50)

References (50)
  • 1
    • 80055008140 scopus 로고    scopus 로고
    • Hydrogen peroxide: A Jekyll and Hyde signalling molecule
    • Gough DR and Cotter TG: Hydrogen peroxide: a Jekyll and Hyde signalling molecule. Cell Death Dis 2: e213, 2011.
    • (2011) Cell Death Dis , vol.2
    • Gough, D.R.1    Cotter, T.G.2
  • 2
    • 0342958723 scopus 로고
    • The effect of oxygen and of hydrogen peroxide on the action of a specific gene and on tumor induction in drosophila melanogaster
    • Plaine HL: The effect of oxygen and of hydrogen peroxide on the action of a specific gene and on tumor induction in drosophila melanogaster. Genetics 40: 268-280, 1955.
    • (1955) Genetics , vol.40 , pp. 268-280
    • Plaine, H.L.1
  • 4
    • 84861309322 scopus 로고    scopus 로고
    • Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia
    • Armogida M, Nistico R and Mercuri NB: Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia. Br J Pharmacol 166: 1211-1224, 2012.
    • (2012) Br J Pharmacol , vol.166 , pp. 1211-1224
    • Armogida, M.1    Nistico, R.2    Mercuri, N.B.3
  • 5
    • 33746016268 scopus 로고    scopus 로고
    • Mitochondria: More Than Just a Powerhouse
    • DOI 10.1016/j.cub.2006.06.054, PII S0960982206017817
    • McBride HM, Neuspiel M and Wasiak S: Mitochondria: more than just a powerhouse. Curr Biol 16: R551-R560, 2006. (Pubitemid 44066793)
    • (2006) Current Biology , vol.16 , Issue.14
    • McBride, H.M.1    Neuspiel, M.2    Wasiak, S.3
  • 6
    • 10844280686 scopus 로고    scopus 로고
    • Mitochondria and neuronal death/survival signaling pathways in cerebral ischemia
    • Chan PH: Mitochondria and neuronal death/survival signaling pathways in cerebral ischemia. Neurochem Res 29: 1943-1949, 2004.
    • (2004) Neurochem Res , vol.29 , pp. 1943-1949
    • Chan, P.H.1
  • 7
    • 79951577369 scopus 로고    scopus 로고
    • Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats
    • Ye R, Yang Q, Kong X, et al: Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats. Neurochem Int 58: 391-398, 2011.
    • (2011) Neurochem Int , vol.58 , pp. 391-398
    • Ye, R.1    Yang, Q.2    Kong, X.3
  • 8
    • 34249083199 scopus 로고    scopus 로고
    • Sirtuins in mammals: Insights into their biological function
    • DOI 10.1042/BJ20070140
    • Michan S and Sinclair D: Sirtuins in mammals: insights into their biological function. Biochem J 404: 1-13, 2007. (Pubitemid 46788079)
    • (2007) Biochemical Journal , vol.404 , Issue.1 , pp. 1-13
    • Michan, S.1    Sinclair, D.2
  • 9
    • 84879026707 scopus 로고    scopus 로고
    • SIRT3 regulation of mitochondrial oxidative stress
    • Bause AS and Haigis MC: SIRT3 regulation of mitochondrial oxidative stress. Exp Gerontol 48: 634-639, 2013.
    • (2013) Exp Gerontol , vol.48 , pp. 634-639
    • Bause, A.S.1    Haigis, M.C.2
  • 10
    • 53549105529 scopus 로고    scopus 로고
    • SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
    • Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB and Gupta MP: SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 28: 6384-6401, 2008.
    • (2008) Mol Cell Biol , vol.28 , pp. 6384-6401
    • Sundaresan, N.R.1    Samant, S.A.2    Pillai, V.B.3    Rajamohan, S.B.4    Gupta, M.P.5
  • 11
    • 84879059766 scopus 로고    scopus 로고
    • SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage
    • Tseng AH, Shieh SS and Wang DL: SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage. Free Radic Biol Med 63: 222-234, 2013.
    • (2013) Free Radic Biol Med , vol.63 , pp. 222-234
    • Tseng, A.H.1    Shieh, S.S.2    Wang, D.L.3
  • 12
    • 84858297200 scopus 로고    scopus 로고
    • SIRT3 gene expression: A link between inherited mitochondrial DNA variants and oxidative stress
    • D'Aquila P, Rose G, Panno ML, Passarino G and Bellizzi D: SIRT3 gene expression: a link between inherited mitochondrial DNA variants and oxidative stress. Gene 497: 323-329, 2012.
    • (2012) Gene , vol.497 , pp. 323-329
    • D'Aquila, P.1    Rose, G.2    Panno, M.L.3    Passarino, G.4    Bellizzi, D.5
  • 13
    • 0027484368 scopus 로고
    • Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase
    • DOI 10.1016/0014-5793(93)80498-J
    • Estornell E, Fato R, Pallotti F and Lenaz G: Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase. FEBS Lett 332: 127-131, 1993. (Pubitemid 23295913)
    • (1993) FEBS Letters , vol.332 , Issue.1-2 , pp. 127-131
    • Estornell, E.1    Fato, R.2    Pallotti, F.3    Lenaz, G.4
  • 14
    • 42949146604 scopus 로고    scopus 로고
    • Ischemic preconditioning targets the respiration of synaptic mitochondria via protein kinase C epsilon
    • Dave KR, DeFazio RA, Raval AP, et al: Ischemic preconditioning targets the respiration of synaptic mitochondria via protein kinase C epsilon. J Neurosci 28: 4172-4182, 2008.
    • (2008) J Neurosci , vol.28 , pp. 4172-4182
    • Dave, K.R.1    DeFazio, R.A.2    Raval, A.P.3
  • 15
    • 0025836574 scopus 로고
    • Decreased activities of ubiquinol:ferricytochrome c oxidoreductase (complex III) and ferrocytochrome c:oxygen oxidoreductase (complex IV) in liver mitochondria from rats with hydroxycobalamin[c-lactam]-induced methylmalonic aciduria
    • Krahenbuhl S, Chang M, Brass EP and Hoppel CL: Decreased activities of ubiquinol:ferricytochrome c oxidoreductase (complex III) and ferrocytochrome c:oxygen oxidoreductase (complex IV) in liver mitochondria from rats with hydroxycobalamin[c-lactam]- induced methylmalonic aciduria. J Biol Chem 266: 20998-21003, 1991. (Pubitemid 21908564)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.31 , pp. 20998-21003
    • Krahenbuhl, S.1    Chang, M.2    Brass, E.P.3    Hoppel, C.L.4
  • 16
    • 84874914445 scopus 로고    scopus 로고
    • Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis
    • Parone PA, Da Cruz S, Han JS, et al: Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis. J Neurosci 33: 4657-4671, 2013.
    • (2013) J Neurosci , vol.33 , pp. 4657-4671
    • Parone, P.A.1    Da Cruz, S.2    Han, J.S.3
  • 17
    • 84878131673 scopus 로고    scopus 로고
    • Neuroglobin overexpression inhibits oxygen-glucose deprivation-induced mitochondrial permeability transition pore opening in primary cultured mouse cortical neurons
    • Yu Z, Liu N, Li Y, Xu J and Wang X: Neuroglobin overexpression inhibits oxygen-glucose deprivation-induced mitochondrial permeability transition pore opening in primary cultured mouse cortical neurons. Neurobiol Dis 56: 95-103, 2013.
    • (2013) Neurobiol Dis , vol.56 , pp. 95-103
    • Yu, Z.1    Liu, N.2    Li, Y.3    Xu, J.4    Wang, X.5
  • 20
    • 78649328799 scopus 로고    scopus 로고
    • Sirtuin regulation of mitochondria: Energy production, apoptosis, and signaling
    • Verdin E, Hirschey MD, Finley LW and Haigis MC: Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends Biochem Sci 35: 669-675, 2010.
    • (2010) Trends Biochem Sci , vol.35 , pp. 669-675
    • Verdin, E.1    Hirschey, M.D.2    Finley, L.W.3    Haigis, M.C.4
  • 23
    • 55749084738 scopus 로고    scopus 로고
    • A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
    • Ahn BH, Kim HS, Song S, et al: A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci USA 105: 14447-14452, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14447-14452
    • Ahn, B.H.1    Kim, H.S.2    Song, S.3
  • 24
    • 77449120223 scopus 로고    scopus 로고
    • Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway
    • Pillai VB, Sundaresan NR, Kim G, et al: Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem 285: 3133-3144, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 3133-3144
    • Pillai, V.B.1    Sundaresan, N.R.2    Kim, G.3
  • 25
    • 70349208608 scopus 로고    scopus 로고
    • Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
    • Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A and Gupta MP: Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 119: 2758-2771, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 2758-2771
    • Sundaresan, N.R.1    Gupta, M.2    Kim, G.3    Rajamohan, S.B.4    Isbatan, A.5    Gupta, M.P.6
  • 26
    • 0032170983 scopus 로고    scopus 로고
    • Measurement of the extracellular H2O2 in the brain by microdialysis
    • DOI 10.1016/S1385-299X(98)00018-X, PII S1385299X9800018X
    • Lei B, Adachi N and Arai T: Measurement of the extracellular H2O2 in the brain by microdialysis. Brain Res Brain Res Protoc 3: 33-36, 1998. (Pubitemid 28481502)
    • (1998) Brain Research Protocols , vol.3 , Issue.1 , pp. 33-36
    • Lei, B.1    Adachi, N.2    Arai, T.3
  • 27
    • 0028973482 scopus 로고
    • Requirement for generation of H2O2 for platelet-derived growth factor signal transduction
    • Sundaresan M, Yu ZX, Ferrans VJ, Irani K and Finkel T: Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science 270: 296-299, 1995.
    • (1995) Science , vol.270 , pp. 296-299
    • Sundaresan, M.1    Yu, Z.X.2    Ferrans, V.J.3    Irani, K.4    Finkel, T.5
  • 28
    • 0029053451 scopus 로고
    • Superoxide radical and superoxide dismutases
    • Fridovich I: Superoxide radical and superoxide dismutases. Annu Rev Biochem 64: 97-112, 1995.
    • (1995) Annu Rev Biochem , vol.64 , pp. 97-112
    • Fridovich, I.1
  • 29
    • 24144473653 scopus 로고    scopus 로고
    • Oxidative and antioxidative potential of brain microglial cells
    • Dringen R: Oxidative and antioxidative potential of brain microglial cells. Antioxid Redox Signal 7: 1223-1233, 2005.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1223-1233
    • Dringen, R.1
  • 30
    • 12244291916 scopus 로고    scopus 로고
    • Peroxide detoxification by brain cells
    • DOI 10.1002/jnr.20280, Brain Energy Metabolism: Transporters, Mitochondria and Neurodegeneration
    • Dringen R, Pawlowski PG and Hirrlinger J: Peroxide detoxification by brain cells. J Neurosci Res 79: 157-165, 2005. (Pubitemid 40116430)
    • (2005) Journal of Neuroscience Research , vol.79 , Issue.1-2 , pp. 157-165
    • Dringen, R.1    Pawlowski, P.G.2    Hirrlinger, J.3
  • 31
    • 75349111140 scopus 로고    scopus 로고
    • Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
    • Cimen H, Han MJ, Yang Y, Tong Q, Koc H and Koc EC: Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 49: 304-311, 2010.
    • (2010) Biochemistry , vol.49 , pp. 304-311
    • Cimen, H.1    Han, M.J.2    Yang, Y.3    Tong, Q.4    Koc, H.5    Koc, E.C.6
  • 32
    • 80052291180 scopus 로고    scopus 로고
    • Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
    • Jing E, Emanuelli B, Hirschey MD, et al: Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci USA 108: 14608-14613, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 14608-14613
    • Jing, E.1    Emanuelli, B.2    Hirschey, M.D.3
  • 35
    • 77955291571 scopus 로고    scopus 로고
    • Oxidative stress caused by mitochondrial calcium overload
    • Peng TI and Jou MJ: Oxidative stress caused by mitochondrial calcium overload. Ann NY Acad Sci 1201: 183-188, 2010.
    • (2010) Ann NY Acad Sci , vol.1201 , pp. 183-188
    • Peng, T.I.1    Jou, M.J.2
  • 36
    • 0027933701 scopus 로고
    • Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: Implications for neurodegeneration
    • Dykens JA: Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: implications for neurodegeneration. J Neurochem 63: 584-591, 1994.
    • (1994) J Neurochem , vol.63 , pp. 584-591
    • Dykens, J.A.1
  • 38
    • 84860809347 scopus 로고    scopus 로고
    • SIRT3, a pivotal actor in mitochondrial functions: Metabolism, cell death and aging
    • Giralt A and Villarroya F: SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging. Biochem J 444: 1-10, 2012.
    • (2012) Biochem J , vol.444 , pp. 1-10
    • Giralt, A.1    Villarroya, F.2
  • 39
    • 17144424946 scopus 로고    scopus 로고
    • SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
    • DOI 10.1074/jbc.M414670200
    • Shi T, Wang F, Stieren E and Tong Q: SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 280: 13560-13567, 2005. (Pubitemid 40517248)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.14 , pp. 13560-13567
    • Shi, T.1    Wang, F.2    Stieren, E.3    Tong, Q.4
  • 40
    • 84876070821 scopus 로고    scopus 로고
    • BH3 profiling - Measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions
    • Del Gaizo Moore V and Letai A: BH3 profiling - measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions. Cancer Lett 332: 202-205, 2013.
    • (2013) Cancer Lett , vol.332 , pp. 202-205
    • Del Gaizo Moore, V.1    Letai, A.2
  • 41
    • 33947658447 scopus 로고    scopus 로고
    • Therapeutics targets in the mitochondrial apoptotic pathway
    • DOI 10.1517/14728222.11.4.515
    • Hacker G and Paschen SA: Therapeutic targets in the mitochondrial apoptotic pathway. Expert Opin Ther Targets 11: 515-526, 2007. (Pubitemid 46487599)
    • (2007) Expert Opinion on Therapeutic Targets , vol.11 , Issue.4 , pp. 515-526
    • Hacker, G.1    Paschen, S.A.2
  • 42
    • 79952266729 scopus 로고    scopus 로고
    • Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
    • Hafner AV, Dai J, Gomes AP, et al: Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging 2: 914-923, 2010.
    • (2010) Aging , vol.2 , pp. 914-923
    • Hafner, A.V.1    Dai, J.2    Gomes, A.P.3
  • 43
    • 77951176793 scopus 로고    scopus 로고
    • Sirtuin-3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria
    • Shulga N, Wilson-Smith R and Pastorino JG: Sirtuin-3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria. J Cell Sci 123: 894-902, 2010.
    • (2010) J Cell Sci , vol.123 , pp. 894-902
    • Shulga, N.1    Wilson-Smith, R.2    Pastorino, J.G.3
  • 44
    • 77955347446 scopus 로고    scopus 로고
    • Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
    • Kong X, Wang R, Xue Y, et al: Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PloS One 5: e11707, 2010.
    • (2010) PloS One , vol.5
    • Kong, X.1    Wang, R.2    Xue, Y.3
  • 45
    • 62649152321 scopus 로고    scopus 로고
    • Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction
    • Marfe G, Tafani M, Indelicato M, et al: Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction. J Cell Biochem 106: 643-650, 2009.
    • (2009) J Cell Biochem , vol.106 , pp. 643-650
    • Marfe, G.1    Tafani, M.2    Indelicato, M.3
  • 46
    • 36849002444 scopus 로고    scopus 로고
    • SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways
    • Allison SJ and Milner J: SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways. Cell Cycle 6: 2669-2677, 2007. (Pubitemid 350224051)
    • (2007) Cell Cycle , vol.6 , Issue.21 , pp. 2669-2677
    • Allison, S.J.1    Milner, J.2
  • 48
    • 79952353862 scopus 로고    scopus 로고
    • Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture
    • Kim SH, Lu HF and Alano CC: Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture. PloS One 6: e14731, 2011.
    • (2011) PloS One , vol.6
    • Kim, S.H.1    Lu, H.F.2    Alano, C.C.3
  • 49
    • 84895835925 scopus 로고    scopus 로고
    • Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration
    • Kincaid B and Bossy-Wetzel E: Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration. Front Aging Neurosci 5: 48, 2013.
    • (2013) Front Aging Neurosci , vol.5 , pp. 48
    • Kincaid, B.1    Bossy-Wetzel, E.2
  • 50
    • 84892411578 scopus 로고    scopus 로고
    • Pre-diabetes alters testicular PGC1-alpha/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress
    • Rato L, Duarte AI, Tomas GD, et al: Pre-diabetes alters testicular PGC1-alpha/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress. Biochim Biophys Acta 1837: 335-344, 2014.
    • (2014) Biochim Biophys Acta , vol.1837 , pp. 335-344
    • Rato, L.1    Duarte, A.I.2    Tomas, G.D.3


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