Neuroglobin overexpression inhibits oxygen-glucose deprivation-induced mitochondrial permeability transition pore opening in primary cultured mouse cortical neurons

Neurobiology of Disease

Volumn 56, Issue , 2013, Pages 95-103

  Yu, Zhanyang ^a,b   Liu, Ning ^a,b   Li, Yadan ^a,b   Xu, Jianfeng ^a,b   Wang, Xiaoying ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cytochrome c; Mitochondria permeability transition pore (mPTP); Mitochondria swelling; NAD+ release; Neuroglobin; Oxygen glucose deprivation

Indexed keywords

CYCLOSPORIN A; CYTOCHROME C; GLUCOSE; NEUROGLOBIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXYGEN; RECOMBINANT NEUROGLOBIN; RECOMBINANT PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL HYPOXIA; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; EMBRYO; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL PERMEABILITY TRANSITION PORE OPENING; MITOCHONDRION SWELLING; MOUSE; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION;

ANIMALS; ANOXIA; BLOTTING, WESTERN; CELL DEATH; CEREBRAL CORTEX; CYCLOSPORINE; CYTOCHROMES C; DEPENDOVIRUS; GLOBINS; GLUCOSE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; L-LACTATE DEHYDROGENASE; MICE; MITOCHONDRIA; MITOCHONDRIAL SWELLING; NAD; NERVE TISSUE PROTEINS; NEURONS; PERMEABILITY; PRIMARY CELL CULTURE; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 84878131673     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.04.015     Document Type: Article

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