Delivery of antisense oligonucleotides using poly(alkylene oxide)-poly(propylacrylic acid) graft copolymers in conjunction with cationic liposomes

Journal of Controlled Release

Volumn 194, Issue , 2014, Pages 103-112

  Peddada, Lavanya Y ^a   Garbuzenko, Olga B ^b   Devore, David I ^d   Minko, Tamara ^b   Roth, Charles M ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c The State University of New Jersey   (United States)

^d US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Antisense; Drug delivery; Gene silencing; Nanoparticle; Self assembly; Tumor

Indexed keywords

NANOPARTICLES; SELF ASSEMBLY; TUMORS;

ANTISENSE; ANTISENSE OLIGONUCLEOTIDES; CATIONIC LIPOSOMES; GENE SILENCING; POLY(ALKYLENE OXIDE);

DRUG DELIVERY;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ANTISENSE OLIGONUCLEOTIDE; CATION; COPOLYMER; NANOCARRIER; PLASMID DNA; POLY(ALKYLENE OXIDE) POLY(PROPYLACRYLIC ACID) GRAFT COPOLYMER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; ACRYLIC ACID RESIN; DIPALMITOYLPHOSPHATIDYLCHOLINE; DRUG CARRIER; LIPOSOME; MACROGOL DERIVATIVE; NANOPARTICLE; POLY(N-ISOPROPYLACRYLAMIDE-CO-PROPYLACRYLIC ACID);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTISENSE THERAPY; ARTICLE; DELIVERY; GENE SILENCING; HEMOLYSIS; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIPOPHILICITY; LIPOSOMAL GENE DELIVERY SYSTEM; LIPOSOME MEMBRANE; MOUSE; NEOPLASM; NONHUMAN; OVARY CANCER; OVARY TUMOR; PROTON NUCLEAR MAGNETIC RESONANCE; REAL TIME POLYMERASE CHAIN REACTION; SYNTHESIS; ULTRAVIOLET SPECTROPHOTOMETRY; XENOGRAFT; ANIMAL; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENE THERAPY; GENETICS; NEOPLASMS; NUDE MOUSE; PROCEDURES; PROTO ONCOGENE; TISSUE DISTRIBUTION; TUMOR CELL LINE;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ACRYLAMIDES; ACRYLIC RESINS; ANIMALS; CATIONS; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; GENE SILENCING; GENES, BCL-2; GENETIC THERAPY; HEMOLYSIS; HUMANS; LIPOSOMES; MICE; MICE, NUDE; NANOPARTICLES; NEOPLASMS; OLIGONUCLEOTIDES, ANTISENSE; POLYETHYLENE GLYCOLS; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84907211287     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.08.023     Document Type: Article

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