Recharging cationic DNA complexes with highly charge polyanions for in vitro and in vivo gene delivery

Gene Therapy

Volumn 10, Issue 3, 2003, Pages 261-271

  Trubetskoy, V S ^a   Wong, S C ^a   Subbotin, V ^a   Budker, V G ^b   Loomis, A ^a   Hagstrom, J E ^a   Wolff, J A ^b  

^a Mirus Bio Corporation   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Cationic lipids; Lipoplex; Non viral gene transfer; Polyanions; Polyethyleneimine; Polyplex

Indexed keywords

CATION; LIPID; PLASMID DNA; POLYACRYLIC ACID; POLYANION; POLYCATION; POLYETHYLENEIMINE; PROTEIN;

ANIMAL CELL; CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG FORMULATION; FLOCCULATION; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER; LUNG; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OPSONIZATION; PARTICLE SIZE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW;

ACRYLIC RESINS; ANIMALS; ANIONS; BETA-GALACTOSIDASE; GENE EXPRESSION; GENE THERAPY; GENETIC ENGINEERING; LIPOSOMES; LUCIFERASES; LUNG; LUNG DISEASES; MALE; MICE; MICE, INBRED ICR; MICROINJECTIONS; POLYETHYLENEIMINE; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; PAA;

EID: 0037320758     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301888     Document Type: Review

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