Unraveling the mechanism of neuroprotection of curcumin in arsenic induced cholinergic dysfunctions in rats

Toxicology and Applied Pharmacology

Volumn 279, Issue 3, 2014, Pages 428-440

  Srivastava, Pranay ^a   Yadav, Rajesh S ^a,b   Chandravanshi, Lalit P ^a   Shukla, Rajendra K ^a   Dhuriya, Yogesh K ^a   Chauhan, Lalit K S ^a   Dwivedi, Hari N ^c   Pant, Aditiya B ^a   Khanna, Vinay K ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b DR H S GOUR UNIVERSITY   (India)

^c UNIVERSITY OF LUCKNOW   (India)

Author keywords

Apoptosis; Arsenic; Curcumin; Mitochondrial damage; Neuroprotection; Rat brain

Indexed keywords

ARSENIC; CHOLINERGIC RECEPTOR; CURCUMIN; CYTOCHROME C OXIDASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; COMPLEMENTARY DNA; MUSCARINIC M2 RECEPTOR; NEUROPROTECTIVE AGENT; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFICACY; DRUG MECHANISM; ENERGY METABOLISM; ENZYME ACTIVITY; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANICS; MYELIN SHEATH; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN CONTENT; RAT; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT DURATION; ANIMAL TISSUE; CELL LOSS; CHOLINERGIC DYSFUNCTION; COMPARATIVE STUDY; DRUG INDUCED DISEASE; GENETIC ASSOCIATION; RNA EXTRACTION; ULTRASTRUCTURE;

APOPTOSIS; ARSENIC; CURCUMIN; MITOCHONDRIAL DAMAGE; NEUROPROTECTION; RAT BRAIN;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ARSENIC POISONING; AUTONOMIC NERVOUS SYSTEM DISEASES; BRAIN; BRAIN CHEMISTRY; CURCUMIN; HIPPOCAMPUS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PREFRONTAL CORTEX; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, MUSCARINIC;

EID: 84907171837     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.06.006     Document Type: Article

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