Dual effects of curcumin on neuronal oxidative stress in the presence of Cu(II)

Food and Chemical Toxicology

Volumn 49, Issue 7, 2011, Pages 1578-1583

  Huang, Han Chang ^a,b   Lin, Chang Jun ^b   Liu, Wen Juan ^b   Jiang, Rui Rui ^b   Jiang, Zhao Feng ^b  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b BEIJING UNION UNIVERSITY   (China)

Author keywords

Alzheimer's disease (AD); Anti oxidation; Copper; Curcumin; Oxidative stress; Pro oxidation

Indexed keywords

CUPRIC ION; CURCUMIN; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL STRUCTURE; CELL VIABILITY; CHROMOSOME ABERRATION; CHROMOSOME CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DISEASE EXACERBATION; DOWN REGULATION; NERVE CELL LESION; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PERIKARYON; RAT; UPREGULATION;

ALZHEIMER DISEASE; ANIMALS; ANTIOXIDANTS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; COPPER; CURCUMIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HOMEOSTASIS; NEURONS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

RATTUS;

EID: 79957643523     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.04.004     Document Type: Article

References (61)

1. Agarwal K., Sharma A., Talukder G. Effects of copper on mammalian cell components. Chem. Biol. Interact. 1989, 69:1-16.
2. Agarwal R., Kushwaha S.S., Tripathi C.B., Singh N., Chhillar N. Serum copper in Alzheimer's disease and vascular dementia. Indian J. Clin. Biochem. 2008, 23:369-374.
3. Augustin S., Rimbach G., Augustin K., Schliebs R., Wolffram S., Cermak R. Effect of a short- and long-term treatment with Ginkgo biloba extract on amyloid precursor protein levels in a transgenic mouse model relevant to Alzheimer's disease. Arch. Biochem. Biophys. 2009, 481:177-182.
4. Banci L., Bertini I., Cantini F., Ciofi-Baffoni S. Cellular copper distribution: a mechanistic systems biology approach. Cell. Mol. Life Sci. 2010, 67:2563-2589.
5. Banci L., Bertini I., Ciofi-Baffoni S., Kozyreva T., Zovo K., Palumaa P. Affinity gradients drive copper to cellular destinations. Nature 2010, 465:645-648.
6. Barik A., Mishra B., Shen L., Mohan H., Kadam R.M., Dutta S., Zhang H.Y., Priyadarsini K.I. Evaluation of a new copper(II)-curcumin complex as superoxide dismutase mimic and its free radical reactions. Free Radic. Biol. Med. 2005, 39:811-822.
7. Baum, L., Ng, A., 2004. Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models. J. Alzheimers Dis. 6, 367-377 (discussion 443-369).
8. Boal A.K., Rosenzweig A.C. Structural biology of copper trafficking. Chem. Rev. 2009, 109:4760-4779.
9. Brewer G.J. The risks of free copper in the body and the development of useful anticopper drugs. Curr. Opin. Clin. Nutr. Metab. Care 2008, 11:727-732.
10. Brewer G.J. Why vitamin E therapy fails for treatment of Alzheimer's disease. J Alzheimers Dis 2010, 19:27-30.
11. Bucossi, S., Ventriglia, M., Panetta, V., Salustri, C., Pasqualetti, P., Mariani, S., Siotto, M., Rossini, P.M., Squitti, R., 2010. Copper in Alzheimer's disease: a meta-analysis of serum, plasma, and cerebrospinal fluid studies. J Alzheimers Dis.
12. Choudhry, F., Howlett, D.R., Richardson, J.C., Francis, P.T., Williams, R.J., 2010. Pro-oxidant diet enhances beta/gamma secretase-mediated APP processing in APP/PS1 transgenic mice. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2010.07.008.
13. Cui Z., Lockman P.R., Atwood C.S., Hsu C.H., Gupte A., Allen D.D., Mumper R.J. Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases. Eur. J. Pharm. Biopharm. 2005, 59:263-272.
14. Dai X., Sun Y., Jiang Z. Protective effects of vitamin E against oxidative damage induced by Abeta1-40Cu(II) complexes. Acta Biochim. Biophys. Sin (Shanghai) 2007, 39:123-130.
15. Darzynkiewicz Z., Bruno S., Del Bino G., Gorczyca W., Hotz M.A., Lassota P., Traganos F. Features of apoptotic cells measured by flow cytometry. Cytometry 1992, 13:795-808.
16. De Feo C.J., Aller S.G., Siluvai G.S., Blackburn N.J., Unger V.M. Three-dimensional structure of the human copper transporter hCTR1. Proc. Natl. Acad. Sci. USA 2009, 106:4237-4242.
17. Di Vaira M., Bazzicalupi C., Orioli P., Messori L., Bruni B., Zatta P. Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes. Inorg. Chem. 2004, 43:3795-3797.
18. Duce J.A., Bush A.I. Biological metals and Alzheimer's disease: implications for therapeutics and diagnostics. Prog. Neurobiol. 2010, 92:1-18.
19. Faux N.G., Ritchie C.W., Gunn A., Rembach A., Tsatsanis A., Bedo J., Harrison J., Lannfelt L., Blennow K., Zetterberg H., Ingelsson M., Masters C.L., Tanzi R.E., Cummings J.L., Herd C.M., Bush A.I. PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. J Alzheimers Dis 2010, 20:509-516.
20. Freimoser F.M., Jakob C.A., Aebi M., Tuor U. The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay is a fast and reliable method for colorimetric determination of fungal cell densities. Appl. Environ. Microbiol. 1999, 65:3727-3729.
21. Fu Y., Zheng S., Lin J., Ryerse J., Chen A. Curcumin protects the rat liver from CCl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation. Mol. Pharmacol. 2008, 73:399-409.
22. Garcia T., Ribes D., Colomina M.T., Cabre M., Domingo J.L., Gomez M. Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease. Toxicology 2009, 265:49-55.
23. Hamaguchi T., Ono K., Yamada M. REVIEW: Curcumin and Alzheimer's disease. CNS Neurosci. Ther. 2010, 16:285-297.
24. Hassanane M.M., Ahmed E.S., Shoman T.M., Ezz-Eldin A. Evaluation of the genotoxicity and antigenotoxicity of curcumin by chromosomal aberrations and biochemical studies in the Albino rats exposed to methotrexate. Global Veterinaria 2010, 4:185-189.
25. Hatcher H., Planalp R., Cho J., Torti F.M., Torti S.V. Curcumin: from ancient medicine to current clinical trials. Cell. Mol. Life Sci. 2008, 65:1631-1652.
26. Huang H.C., Jiang Z.F. Accumulated amyloid-beta peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease. J. Alzheimers Dis. 2009, 16:15-27.
27. Jo D.G., Arumugam T.V., Woo H.N., Park J.S., Tang S.C., Mughal M., Hyun D.H., Park J.H., Choi Y.H., Gwon A.R., Camandola S., Cheng A., Cai H., Song W., Markesbery W.R., Mattson M.P. Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease. Neurobiol. Aging 2010, 31:917-925.
28. Lannfelt L., Blennow K., Zetterberg H., Batsman S., Ames D., Harrison J., Masters C.L., Targum S., Bush A.I., Murdoch R., Wilson J., Ritchie C.W. Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. Lancet Neurol. 2008, 7:779-786.
29. Leary S.C., Winge D.R. The Janus face of copper: its expanding roles in biology and the pathophysiology of disease. Meeting on Copper and Related Metals in Biology. EMBO Rep. 2007, 8:224-227.
30. Lin C.J., Huang H.C., Jiang Z.F. Cu(II) interaction with amyloid-beta peptide: a review of neuroactive mechanisms in AD brains. Brain Res. Bull. 2010, 82:235-242.
31. Lovell M.A., Robertson J.D., Teesdale W.J., Campbell J.L., Markesbery W.R. Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurol. Sci. 1998, 158:47-52.
32. Mangialasche F., Kivipelto M., Mecocci P., Rizzuto D., Palmer K., Winblad B., Fratiglioni L. High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age. J. Alzheimers Dis. 2010, 20:1029-1037.
33. Maurizi C.P. Choroid plexus portals and a deficiency of melatonin can explain the neuropathology of Alzheimer's disease. Med. Hypotheses 2010, 74:1059-1066.
34. Miller L.M., Wang Q., Telivala T.P., Smith R.J., Lanzirotti A., Miklossy J. Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease. J. Struct. Biol. 2006, 155:30-37.
35. Multhaup G., Schlicksupp A., Hesse L., Beher D., Ruppert T., Masters C.L., Beyreuther K. The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I). Science 1996, 271:1406-1409.
36. Ritchie C.W., Bush A.I., Mackinnon A., Macfarlane S., Mastwyk M., MacGregor L., Kiers L., Cherny R., Li Q.X., Tammer A., Carrington D., Mavros C., Volitakis I., Xilinas M., Ames D., Davis S., Beyreuther K., Tanzi R.E., Masters C.L. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch. Neurol. 2003, 60:1685-1691.
37. Rival T., Page R.M., Chandraratna D.S., Sendall T.J., Ryder E., Liu B., Lewis H., Rosahl T., Hider R., Camargo L.M., Shearman M.S., Crowther D.C., Lomas D.A. Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease. Eur. J. NeuroSci. 2009, 29:1335-1347.
38. Rogers J.T., Bush A.I., Cho H.H., Smith D.H., Thomson A.M., Friedlich A.L., Lahiri D.K., Leedman P.J., Huang X., Cahill C.M. Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease. Biochem. Soc. Trans. 2008, 36:1282-1287.
39. Rogers J.T., Leiter L.M., McPhee J., Cahill C.M., Zhan S.S., Potter H., Nilsson L.N. Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences. J. Biol. Chem. 1999, 274:6421-6431.
40. Rossi L., Squitti R., Calabrese L., Rotilio G., Rossini P.M. Alteration of peripheral markers of copper homeostasis in Alzheimer's disease patients: implications in aetiology and therapy. J. Nutr. Health Aging 2007, 11:408-417.
41. Rossi L., Squitti R., Pasqualetti P., Marchese E., Cassetta E., Forastiere E., Rotilio G., Rossini P.M., Finazzi-Agro A. Red blood cell copper, zinc superoxide dismutase activity is higher in Alzheimer's disease and is decreased by d-penicillamine. Neurosci. Lett. 2002, 329:137-140.
42. Salustri C., Barbati G., Ghidoni R., Quintiliani L., Ciappina S., Binetti G., Squitti R. Is cognitive function linked to serum free copper levels? A cohort study in a normal population. Clin. Neurophysiol. 2010, 121:502-507.
43. Shi C., Liu J., Wu F., Yew D.T. Ginkgo biloba extract in Alzheimer's disease: from action mechanisms to medical practice. Int. J. Mol. Sci. 2010, 11:107-123.
44. Siotto M., Bucossi S., Squitti R. Copper status abnormalities and how to measure them in neurodegenerative disorders. Recent Pat. CNS Drug Discov. 2010, 5:182-194.
45. Squitti R., Ghidoni R., Scrascia F., Benussi L., Panetta V., Pasqualetti P., Moffa F., Bernardini S., Ventriglia M., Binetti G., Rossini P.M. Free copper distinguishes mild cognitive impairment subjects from healthy elderly individuals. J. Alzheimers Dis. 2011, 23:239-248.
46. Squitti R., Lupoi D., Pasqualetti P., Dal Forno G., Vernieri F., Chiovenda P., Rossi L., Cortesi M., Cassetta E., Rossini P.M. Elevation of serum copper levels in Alzheimer's disease. Neurology 2002, 59:1153-1161.
47. Squitti R., Rossini P.M., Cassetta E., Moffa F., Pasqualetti P., Cortesi M., Colloca A., Rossi L., Finazzi-Agro A. d-penicillamine reduces serum oxidative stress in Alzheimer's disease patients. Eur. J. Clin. Invest. 2002, 32:51-59.
48. Squitti R., Salustri C. Agents complexing copper as a therapeutic strategy for the treatment of Alzheimer's disease. Curr. Alzheimer Res. 2009, 6:476-487.
49. Squitti R., Zito G. Anti-copper therapies in Alzheimer's disease: new concepts. Recent Pat. CNS Drug Discov. 2009, 4:209-219.
50. Strozyk D., Launer L.J., Adlard P.A., Cherny R.A., Tsatsanis A., Volitakis I., Blennow K., Petrovitch H., White L.R., Bush A.I. Zinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluid. Neurobiol. Aging 2009, 30:1069-1077.
51. Suazo M., Hodar C., Morgan C., Cerpa W., Cambiazo V., Inestrosa N.C., Gonzalez M. Overexpression of amyloid precursor protein increases copper content in HEK293 cells. Biochem. Biophys. Res. Commun. 2009, 382:740-744.
52. Tiraboschi P., Hansen L.A., Thal L.J., Corey-Bloom J. The importance of neuritic plaques and tangles to the development and evolution of AD. Neurology 2004, 62:1984-1989.
53. Tougu V., Karafin A., Zovo K., Chung R.S., Howells C., West A.K., Palumaa P. Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators. J. Neurochem. 2009, 110:1784-1795.
54. Tougu V., Tiiman A., Palumaa P. Interactions of Zn(ii) and Cu(ii) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity. Metallomics 2011, 3:250-261.
55. Urbina-Cano P., Bobadilla-Morales L., Ramirez-Herrera M.A., Corona-Rivera J.R., Mendoza-Magana M.L., Troyo-Sanroman R., Corona-Rivera A. DNA damage in mouse lymphocytes exposed to curcumin and copper. J. Appl. Genet. 2006, 47:377-382.
56. Usoro O.B., Mousa S.A. Vitamin E forms in Alzheimer's disease: a review of controversial and clinical experiences. Crit. Rev. Food Sci. Nutr. 2010, 50:414-419.
57. Voskoboinik I., Camakaris J. Menkes copper-translocating P-type ATPase (ATP7A): biochemical and cell biology properties, and role in Menkes disease. J. Bioenerg. Biomembr. 2002, 34:363-371.
58. Xu W., Huang H.C., Lin C.J., Jiang Z.F. Chitooligosaccharides protect rat cortical neurons against copper induced damage by attenuating intracellular level of reactive oxygen species. Bioorg. Med. Chem. Lett. 2010, 20:3084-3088.
59. Yang F., Lim G.P., Begum A.N., Ubeda O.J., Simmons M.R., Ambegaokar S.S., Chen P.P., Kayed R., Glabe C.G., Frautschy S.A., Cole G.M. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J. Biol. Chem. 2005, 280:5892-5901.
60. Yang L., McRae R., Henary M.M., Patel R., Lai B., Vogt S., Fahrni C.J. Imaging of the intracellular topography of copper with a fluorescent sensor and by synchrotron x-ray fluorescence microscopy. Proc. Natl. Acad. Sci, USA 2005, 102:11179-11184.
61. Zhang C., Browne A., Child D., Tanzi R.E. Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein. J. Biol. Chem. 2010, 285:28472-28480.