-
1
-
-
67650478963
-
Single-dose administration of MK-0657, an NR2B-selective NMDA antagonist, does not result in clinically meaningful improvement in motor function in patients with moderate Parkinson's disease
-
Addy C, Assaid C, Hreniuk D et al (2009) Single-dose administration of MK-0657, an NR2B-selective NMDA antagonist, does not result in clinically meaningful improvement in motor function in patients with moderate Parkinson's disease. J Clin Pharmacol 49:856-864. doi:10.1177/0091270009336735
-
(2009)
J Clin Pharmacol
, vol.49
, pp. 856-864
-
-
Addy, C.1
Assaid, C.2
Hreniuk, D.3
-
2
-
-
0033360182
-
Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems
-
Alagarsamy S, Marino MJ, Rouse ST et al (1999) Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems. Nat Neurosci 2:234-240. doi:10.1038/6338
-
(1999)
Nat Neurosci
, vol.2
, pp. 234-240
-
-
Alagarsamy, S.1
Marino, M.J.2
Rouse, S.T.3
-
3
-
-
0026609559
-
Alternative excitotoxic hypotheses
-
Albin RL, Greenamyre JT (1992) Alternative excitotoxic hypotheses. Neurology 42:733-738
-
(1992)
Neurology
, vol.42
, pp. 733-738
-
-
Albin, R.L.1
Greenamyre, J.T.2
-
4
-
-
84867672006
-
Effect of oestrogen receptors on brain NMDA receptors of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice
-
Al-Sweidi S, Morissette M, Di Paolo T (2012) Effect of oestrogen receptors on brain NMDA receptors of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice. J Neuroendocrinol 24:1375-1385. doi:10.1111/j.1365-2826.2012.02349.x
-
(2012)
J Neuroendocrinol
, vol.24
, pp. 1375-1385
-
-
Al-Sweidi, S.1
Morissette, M.2
Di Paolo, T.3
-
5
-
-
84872156818
-
Group III and subtype 4 metabotropic glutamate receptor agonists: Discovery and pathophysiological applications in Parkinson's disease
-
Amalric M, Lopez S, Goudet C et al (2013) Group III and subtype 4 metabotropic glutamate receptor agonists: discovery and pathophysiological applications in Parkinson's disease. Neuropharmacology 66:53-64. doi:10.1016/j.neuropharm.2012.05.026
-
(2013)
Neuropharmacology
, vol.66
, pp. 53-64
-
-
Amalric, M.1
Lopez, S.2
Goudet, C.3
-
6
-
-
77952319804
-
Effects of early and delayed treatment with an mGluR5 antagonist on motor impairment, nigrostriatal damage and neuroinflammation in a rodent model of Parkinson's disease
-
Ambrosi G, Armentero M-T, Levandis G et al (2010) Effects of early and delayed treatment with an mGluR5 antagonist on motor impairment, nigrostriatal damage and neuroinflammation in a rodent model of Parkinson's disease. Brain Res Bull 82:29-38. doi:10.1016/j.brainresbull.2010.01.011
-
(2010)
Brain Res Bull
, vol.82
, pp. 29-38
-
-
Ambrosi, G.1
Armentero, M.-T.2
Levandis, G.3
-
7
-
-
33645090418
-
Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease
-
Armentero M-T, Fancellu R, Nappi G et al (2006) Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease. Neurobiol Dis 22:1-9. doi:10.1016/j.nbd. 2005.09.010
-
(2006)
Neurobiol Dis
, vol.22
, pp. 1-9
-
-
Armentero, M.-T.1
Fancellu, R.2
Nappi, G.3
-
8
-
-
33748272252
-
Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons
-
Bak LK, Schousboe A, Sonnewald U, Waagepetersen HS (2006) Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons. J Cereb Blood Flow Metab 26:1285-1297. doi:10.1038/sj. jcbfm.9600281
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 1285-1297
-
-
Bak, L.K.1
Schousboe, A.2
Sonnewald, U.3
Waagepetersen, H.S.4
-
9
-
-
34248152778
-
Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation
-
Barger SW, Goodwin ME, Porter MM, Beggs ML (2007) Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation. J Neurochem 101:1205-1213. doi:10.1111/j.1471-4159.2007.04487.x
-
(2007)
J Neurochem
, vol.101
, pp. 1205-1213
-
-
Barger, S.W.1
Goodwin, M.E.2
Porter, M.M.3
Beggs, M.L.4
-
10
-
-
0037493477
-
Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
-
Battaglia G, Busceti CL, Pontarelli F et al (2003) Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Neuropharmacology 45:155-166
-
(2003)
Neuropharmacology
, vol.45
, pp. 155-166
-
-
Battaglia, G.1
Busceti, C.L.2
Pontarelli, F.3
-
11
-
-
0742322858
-
Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
-
Battaglia G, Busceti CL, Molinaro G et al (2004) Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. J Neurosci 24:828-835. doi:10.1523/JNEUROSCI.3831-03.2004
-
(2004)
J Neurosci
, vol.24
, pp. 828-835
-
-
Battaglia, G.1
Busceti, C.L.2
Molinaro, G.3
-
12
-
-
33746233386
-
Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Battaglia G, Busceti CL, Molinaro G et al (2006) Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurosci 26:7222-7229. doi:10.1523/JNEUROSCI.1595-06.2006
-
(2006)
J Neurosci
, vol.26
, pp. 7222-7229
-
-
Battaglia, G.1
Busceti, C.L.2
Molinaro, G.3
-
13
-
-
79959372108
-
AFQ056 treatment of levodopa-induced dyskinesias: Results of 2 randomized controlled trials
-
Berg D, Godau J, Trenkwalder C et al (2011) AFQ056 treatment of levodopa-induced dyskinesias: results of 2 randomized controlled trials. Mov Disord 26:1243-1250. doi:10.1002/mds. 23616
-
(2011)
Mov Disord
, vol.26
, pp. 1243-1250
-
-
Berg, D.1
Godau, J.2
Trenkwalder, C.3
-
14
-
-
0035074475
-
Subthalamic infusion of an NMDA antagonist prevents basal ganglia metabolic changes and nigral degeneration in a rodent model of Parkinson's disease
-
Blandini F, Nappi G, Greenamyre JT (2001) Subthalamic infusion of an NMDA antagonist prevents basal ganglia metabolic changes and nigral degeneration in a rodent model of Parkinson's disease. Ann Neurol 49:525-529
-
(2001)
Ann Neurol
, vol.49
, pp. 525-529
-
-
Blandini, F.1
Nappi, G.2
Greenamyre, J.T.3
-
15
-
-
0036662945
-
Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism
-
Breysse N, Baunez C, Spooren W et al (2002) Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism. J Neurosci 22:5669-5678
-
(2002)
J Neurosci
, vol.22
, pp. 5669-5678
-
-
Breysse, N.1
Baunez, C.2
Spooren, W.3
-
16
-
-
0034852645
-
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs
-
Bruno V, Battaglia G, Copani A et al (2001) Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. J Cereb Blood Flow Metab 21:1013-1033. doi:10.1097/00004647-200109000-00001
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 1013-1033
-
-
Bruno, V.1
Battaglia, G.2
Copani, A.3
-
17
-
-
77955961925
-
Neuroprotection and functional recovery associated with decreased microglial activation following selective activation of mGluR2/3 receptors in a rodent model of Parkinson's disease
-
Chan H, Paur H, Vernon AC et al (2010) Neuroprotection and functional recovery associated with decreased microglial activation following selective activation of mGluR2/3 receptors in a rodent model of Parkinson's disease. Parkinsons Dis. doi:10. 4061/2010/190450
-
(2010)
Parkinsons Dis
-
-
Chan, H.1
Paur, H.2
Vernon, A.C.3
-
18
-
-
84862658336
-
AMPA receptors as drug targets in neurological disease-advantages, caveats, and future outlook
-
Chang PK-Y, Verbich D, McKinney RA (2012) AMPA receptors as drug targets in neurological disease-advantages, caveats, and future outlook. Eur J Neurosci 35:1908-1916. doi:10.1111/j.1460-9568.2012.08165.x
-
(2012)
Eur J Neurosci
, vol.35
, pp. 1908-1916
-
-
Chang, P.K.-Y.1
Verbich, D.2
McKinney, R.A.3
-
19
-
-
0034977386
-
Randomized, doubleblind, placebo-controlled, ascending-dose tolerability and safety study of remacemide as adjuvant therapy in Parkinson's disease with response fluctuations
-
Clarke CE, Cooper JA, Holdich TAA (2001) Randomized, doubleblind, placebo-controlled, ascending-dose tolerability and safety study of remacemide as adjuvant therapy in Parkinson's disease with response fluctuations. Clin Neuropharmacol 24:133-138
-
(2001)
Clin Neuropharmacol
, vol.24
, pp. 133-138
-
-
Clarke, C.E.1
Cooper, J.A.2
Holdich, T.A.A.3
-
20
-
-
3242765264
-
Simultaneous blockade of adenosine A2A and metabotropic glutamate mGlu5 receptors increase their efficacy in reversing Parkinsonian deficits in rats
-
Coccurello R, Breysse N, Amalric M (2004) Simultaneous blockade of adenosine A2A and metabotropic glutamate mGlu5 receptors increase their efficacy in reversing Parkinsonian deficits in rats. Neuropsychopharmacology 29:1451-1461. doi:10.1038/sj.npp.1300444
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1451-1461
-
-
Coccurello, R.1
Breysse, N.2
Amalric, M.3
-
21
-
-
0028915585
-
The competitive NMDA antagonists CGP 43487 and APV potentiate dopaminergic function
-
Dall'Olio R, Rimondini R, Gandolfi O (1995) The competitive NMDA antagonists CGP 43487 and APV potentiate dopaminergic function. Psychopharmacology 118:310-315
-
(1995)
Psychopharmacology
, vol.118
, pp. 310-315
-
-
Dall'Olio, R.1
Rimondini, R.2
Gandolfi, O.3
-
22
-
-
0342468278
-
The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits
-
DeCarvalho LP, Bochet P, Rossier J (1996) The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem Int 28:445-452
-
(1996)
Neurochem Int
, vol.28
, pp. 445-452
-
-
DeCarvalho, L.P.1
Bochet, P.2
Rossier, J.3
-
23
-
-
33745919520
-
Epidemiology of Parkinson's disease
-
DeLau LML, Breteler MMB (2006) Epidemiology of Parkinson's disease. Lancet neurol 5:525-535. doi:10.1016/S1474-4422(06) 70471-9
-
(2006)
Lancet neurol
, vol.5
, pp. 525-535
-
-
DeLau, L.M.L.1
Breteler, M.M.B.2
-
24
-
-
84877640168
-
Neurosteroid and neurotransmitter alterations in Parkinson's disease
-
Di Michele F, Luchetti S, Bernardi G et al (2013) Neurosteroid and neurotransmitter alterations in Parkinson's disease. Front Neuroendocrinol 34:132-142. doi:10.1016/j.yfrne.2013.03.001
-
(2013)
Front Neuroendocrinol
, vol.34
, pp. 132-142
-
-
Di Michele, F.1
Luchetti, S.2
Bernardi, G.3
-
25
-
-
0033974271
-
Alterations in subunit expression, composition, and phosphorylation of striatal Nmethyl-D-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease
-
Dunah AW, Wang Y, Yasuda RP et al (2000) Alterations in subunit expression, composition, and phosphorylation of striatal Nmethyl-D-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease. Mol Pharmacol 57:342-352
-
(2000)
Mol Pharmacol
, vol.57
, pp. 342-352
-
-
Dunah, A.W.1
Wang, Y.2
Yasuda, R.P.3
-
26
-
-
77954330278
-
Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease
-
Duty S (2010) Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease. Br J Pharmacol 161:271-287. doi:10.1111/j.1476-5381. 2010.00882.x
-
(2010)
Br J Pharmacol
, vol.161
, pp. 271-287
-
-
Duty, S.1
-
27
-
-
84873417885
-
Targeting glutamate receptors to tackle the pathogenesis, clinical symptoms and levodopa-induced dyskinesia associated with Parkinson's disease
-
Duty S (2012) Targeting glutamate receptors to tackle the pathogenesis, clinical symptoms and levodopa-induced dyskinesia associated with Parkinson's disease. CNS drugs 26:1017-1032. doi:10.1007/s40263-012-0016-z
-
(2012)
CNS drugs
, vol.26
, pp. 1017-1032
-
-
Duty, S.1
-
28
-
-
77951958360
-
Safety and efficacy of perampanel in advanced Parkinson's disease: A randomized, placebo-controlled study
-
Eggert K, Squillacote D, Barone P et al (2010) Safety and efficacy of perampanel in advanced Parkinson's disease: a randomized, placebo-controlled study. Mov Disord 25:896-905. doi:10.1002/mds.22974
-
(2010)
Mov Disord
, vol.25
, pp. 896-905
-
-
Eggert, K.1
Squillacote, D.2
Barone, P.3
-
29
-
-
84863325453
-
N-Methyl-D-Aspartate antagonists in levodopa induced dyskinesia: A meta-analysis
-
Elahi B, Phielipp N, Chen R (2012) N-Methyl-D-Aspartate antagonists in levodopa induced dyskinesia: a meta-analysis. Can J Neurol 39:465-472
-
(2012)
Can J Neurol
, vol.39
, pp. 465-472
-
-
Elahi, B.1
Phielipp, N.2
Chen, R.3
-
30
-
-
34548384722
-
Neurotransmitter receptor heteromers and their integrative role in "local modules": The striatal spine module
-
Ferré S, Agnati LF, Ciruela F et al (2007) Neurotransmitter receptor heteromers and their integrative role in "local modules": the striatal spine module. Brain Res Rev 55:55-67. doi:10.1016/j. brainresrev.2007.01.007
-
(2007)
Brain Res Rev
, vol.55
, pp. 55-67
-
-
Ferré, S.1
Agnati, L.F.2
Ciruela, F.3
-
31
-
-
84872476147
-
Metabolic changes detected by ex vivo high resolution 1H NMR spectroscopy in the striatum of 6-OHDA-induced Parkinson's rat
-
Gao H-C, Zhu H, Song C-Y et al (2013) Metabolic changes detected by ex vivo high resolution 1H NMR spectroscopy in the striatum of 6-OHDA-induced Parkinson's rat. Mol Neurobiol 47:123-130. doi:10.1007/s12035-012-8336-z
-
(2013)
Mol Neurobiol
, vol.47
, pp. 123-130
-
-
Gao, H.-C.1
Zhu, H.2
Song, C.-Y.3
-
32
-
-
80755189958
-
Effect of rasagiline on the molecular composition of the excitatory postsynaptic density
-
Gardoni F, Zianni E, Eramo A et al (2011) Effect of rasagiline on the molecular composition of the excitatory postsynaptic density. Eur J Pharmacol 670:458-463. doi:10.1016/j.ejphar.2011.09.028
-
(2011)
Eur J Pharmacol
, vol.670
, pp. 458-463
-
-
Gardoni, F.1
Zianni, E.2
Eramo, A.3
-
33
-
-
84880293957
-
Metabotropic glutamate receptors for Parkinson's disease therapy
-
Gasparini F, Di Paolo T, Gomez-Mancilla B (2013) Metabotropic glutamate receptors for Parkinson's disease therapy. Parkinsons Dis 2013:196028. doi:10.1155/2013/196028
-
(2013)
Parkinsons Dis
, vol.2013
, pp. 196028
-
-
Gasparini, F.1
Di Paolo, T.2
Gomez-Mancilla, B.3
-
34
-
-
77249085779
-
Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease
-
Greco B, Lopez S, van der Putten H et al (2010) Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease. J Pharmacol Exp Ther 332:1064-1071. doi:10.1124/jpet.109.162115
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 1064-1071
-
-
Greco, B.1
Lopez, S.2
van der Putten, H.3
-
35
-
-
0037301661
-
The Yin and Yang of NMDA receptor signalling
-
Hardingham GE, Bading H (2003) The Yin and Yang of NMDA receptor signalling. Trends Neurosci 26:81-89. doi:10.1016/S0166-2236(02)00040-1
-
(2003)
Trends Neurosci
, vol.26
, pp. 81-89
-
-
Hardingham, G.E.1
Bading, H.2
-
36
-
-
77956917231
-
Synaptic versus extrasynaptic NMDA receptor signalling: Implications for neurodegenerative disorders
-
Hardingham GE, Bading H (2010) Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 11:682-696. doi:10.1038/nrn2911
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 682-696
-
-
Hardingham, G.E.1
Bading, H.2
-
37
-
-
84857705629
-
Therapeutic potential of metabotropic glutamate receptor modulators
-
Hovelsø N, Sotty F, Montezinho LP et al (2012) Therapeutic potential of metabotropic glutamate receptor modulators. Curr Neuropharmacol 10:12-48. doi:10.2174/157015912799362805
-
(2012)
Curr Neuropharmacol
, vol.10
, pp. 12-48
-
-
Hovelsø, N.1
Sotty, F.2
Montezinho, L.P.3
-
38
-
-
84859804848
-
Blockade of metabotropic glutamate receptors inhibits cognition and neurodegeneration in an MPTP-induced Parkinson's disease rat model
-
Hsieh M-H, Ho S-C, Yeh K-Y et al (2012) Blockade of metabotropic glutamate receptors inhibits cognition and neurodegeneration in an MPTP-induced Parkinson's disease rat model. Pharmacol Biochem Behav 102:64-71. doi:10.1016/j.pbb.2012.03.022
-
(2012)
Pharmacol Biochem Behav
, vol.102
, pp. 64-71
-
-
Hsieh, M.-H.1
Ho, S.-C.2
Yeh, K.-Y.3
-
39
-
-
0035337711
-
Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons
-
Huang CC, Lo SW, Hsu KS (2001) Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons. J Physiol 532:731-748
-
(2001)
J Physiol
, vol.532
, pp. 731-748
-
-
Huang, C.C.1
Lo, S.W.2
Hsu, K.S.3
-
40
-
-
0141540782
-
Kainate receptors and synaptic transmission
-
Huettner JE (2003) Kainate receptors and synaptic transmission. Prog Neurobiol 70:387-407
-
(2003)
Prog Neurobiol
, vol.70
, pp. 387-407
-
-
Huettner, J.E.1
-
41
-
-
79955671013
-
AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α synuclein oligomers
-
Hüls S, Högen T, Vassallo N et al (2011) AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α synuclein oligomers. J Neurochem 117:868-878. doi:10.1111/j.1471-4159.2011.07254.x
-
(2011)
J Neurochem
, vol.117
, pp. 868-878
-
-
Hüls, S.1
Högen, T.2
Vassallo, N.3
-
43
-
-
84872139375
-
The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease
-
Johnson KA, Jones CK, Tantawy MN et al (2013) The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease. Neuropharmacology 66:187-195. doi:10.1016/j.neuro pharm.2012.03.029
-
(2013)
Neuropharmacology
, vol.66
, pp. 187-195
-
-
Johnson, K.A.1
Jones, C.K.2
Tantawy, M.N.3
-
44
-
-
27744450594
-
Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice
-
Kachroo A, Orlando LR, Grandy DK et al (2005) Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. J Neurosci 25:10414-10419. doi:10.1523/JNEUROSCI.3660-05.2005
-
(2005)
J Neurosci
, vol.25
, pp. 10414-10419
-
-
Kachroo, A.1
Orlando, L.R.2
Grandy, D.K.3
-
45
-
-
84863337898
-
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons
-
Kaufman AM, Milnerwood AJ, Sepers MD et al (2012) Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. J Neurosci 32:3992-4003. doi:10.1523/JNEUROSCI.4129-11.2012
-
(2012)
J Neurosci
, vol.32
, pp. 3992-4003
-
-
Kaufman, A.M.1
Milnerwood, A.J.2
Sepers, M.D.3
-
46
-
-
0031172429
-
The postsynaptic density at glutamatergic synapses
-
Kennedy MB (1997) The postsynaptic density at glutamatergic synapses. Trends Neurosci 20:264-268
-
(1997)
Trends Neurosci
, vol.20
, pp. 264-268
-
-
Kennedy, M.B.1
-
47
-
-
38949126940
-
Excitotoxicity and new antiglutamatergic strategies in Parkinson's disease and Alzheimer's disease
-
Koutsilieri E, Riederer P (2007) Excitotoxicity and new antiglutamatergic strategies in Parkinson's disease and Alzheimer's disease. Parkinsonism Relat Disord 13(Suppl 3):S329-S331. doi:10.1016/S1353-8020(08)70025-7
-
(2007)
Parkinsonism Relat Disord
, vol.13
, pp. S329-S331
-
-
Koutsilieri, E.1
Riederer, P.2
-
48
-
-
84866331745
-
A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease
-
LePoul E, Boléa C, Girard F et al (2012) A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease. J Pharmacol Exp Ther 343:167-177. doi:10.1124/jpet.112.196063
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 167-177
-
-
LePoul, E.1
Boléa, C.2
Girard, F.3
-
49
-
-
84876741388
-
Neurotransmitters and microglial-mediated neuroinflammation
-
Lee M (2013) Neurotransmitters and microglial-mediated neuroinflammation. Curr Protein Pept Sci 14:21-32
-
(2013)
Curr Protein Pept Sci
, vol.14
, pp. 21-32
-
-
Lee, M.1
-
50
-
-
44549089063
-
Kynurenic acid attenuates MPP(?)-induced dopaminergic neuronal cell death via a Baxmediated mitochondrial pathway
-
Lee DY, Lee K-S, Lee HJ et al (2008) Kynurenic acid attenuates MPP(?)-induced dopaminergic neuronal cell death via a Baxmediated mitochondrial pathway. Eur J Cell Biol 87:389-397. doi:10.1016/j.ejcb.2008.03.003
-
(2008)
Eur J Cell Biol
, vol.87
, pp. 389-397
-
-
Lee, D.Y.1
Lee, K.-S.2
Lee, H.J.3
-
51
-
-
84856952320
-
Perampanel, an AMPA antagonist, found to have no benefit in reducing "off" time in Parkinson's disease
-
Lees A, Fahn S, Eggert KM et al (2012) Perampanel, an AMPA antagonist, found to have no benefit in reducing "off" time in Parkinson's disease. Mov Disord 27:284-288. doi:10.1002/mds.23983
-
(2012)
Mov Disord
, vol.27
, pp. 284-288
-
-
Lees, A.1
Fahn, S.2
Eggert, K.M.3
-
52
-
-
36549085132
-
Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease
-
Levandis G, Bazzini E, Armentero M-T et al (2008) Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease. Neurobiol Dis 29:161-168. doi:10.1016/j.nbd.2007.08.011
-
(2008)
Neurobiol Dis
, vol.29
, pp. 161-168
-
-
Levandis, G.1
Bazzini, E.2
Armentero, M.-T.3
-
53
-
-
34648843243
-
Pathologically activated therapeutics for neuroprotection
-
Lipton SA (2007) Pathologically activated therapeutics for neuroprotection. Nat Rev Neurosci 8:803-808. doi:10.1038/nrn2229
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 803-808
-
-
Lipton, S.A.1
-
54
-
-
84875591435
-
Neuroprotective effect of estrogen: Role of nonsynaptic NR2B-containing NMDA receptors
-
Liu S, Zhao M (2013) Neuroprotective effect of estrogen: role of nonsynaptic NR2B-containing NMDA receptors. Brain Res Bull 93:27-31. doi:10.1016/j.brainresbull.2012.10.004
-
(2013)
Brain Res Bull
, vol.93
, pp. 27-31
-
-
Liu, S.1
Zhao, M.2
-
55
-
-
84857716290
-
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons
-
Lundblad M, Decressac M, Mattsson B, Björklund A (2012) Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons. Proc Natl Acad Sci USA 109:3213-3219. doi:10.1073/pnas.1200575109
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3213-3219
-
-
Lundblad, M.1
Decressac, M.2
Mattsson, B.3
Björklund, A.4
-
56
-
-
84864870837
-
Alpha-synuclein: From secretion to dysfunction and death
-
Marques O, Outeiro TF (2012) Alpha-synuclein: from secretion to dysfunction and death. Cell Death Dis 3:e350. doi:10.1038/cddis.2012.94
-
(2012)
Cell Death Dis
, vol.3
-
-
Marques, O.1
Outeiro, T.F.2
-
57
-
-
0034308136
-
Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation
-
McNaught KS, Jenner P (2000) Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation. Biochem Pharmacol 60:979-988
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 979-988
-
-
McNaught, K.S.1
Jenner, P.2
-
58
-
-
84871919598
-
Excitotoxicity: Bridge to various triggers in neurodegenerative disorders
-
Mehta A, Prabhakar M, Kumar P et al (2013) Excitotoxicity: bridge to various triggers in neurodegenerative disorders. Eur J Pharmacol 698:6-18. doi:10.1016/j.ejphar.2012.10.032
-
(2013)
Eur J Pharmacol
, vol.698
, pp. 6-18
-
-
Mehta, A.1
Prabhakar, M.2
Kumar, P.3
-
59
-
-
79955622718
-
Priorities in Parkinson's disease research
-
Meissner WG, Frasier M, Gasser T et al (2011) Priorities in Parkinson's disease research. Nat Rev Drug Discov 10:377-393. doi:10.1038/nrd3430
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 377-393
-
-
Meissner, W.G.1
Frasier, M.2
Gasser, T.3
-
60
-
-
0032778037
-
The non-NMDA glutamate receptor antagonists 6-cyano-7-nitroquinoxaline-2,3-dione and 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline, but not NMDA antagonists, block the intrastriatal neurotoxic effect of MPP?
-
Merino M, Vizuete ML, Cano J, Machado A (1999) The non-NMDA glutamate receptor antagonists 6-cyano-7-nitroquinoxaline-2,3-dione and 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline, but not NMDA antagonists, block the intrastriatal neurotoxic effect of MPP?. J Neurochem 73:750-757
-
(1999)
J Neurochem
, vol.73
, pp. 750-757
-
-
Merino, M.1
Vizuete, M.L.2
Cano, J.3
Machado, A.4
-
61
-
-
5444258474
-
Innervation of the substantia nigra
-
Misgeld U (2004) Innervation of the substantia nigra. Cell Tissue Res 318:107-114. doi:10.1007/s00441-004-0918-2
-
(2004)
Cell Tissue Res
, vol.318
, pp. 107-114
-
-
Misgeld, U.1
-
62
-
-
84865320895
-
Self-induced accumulation of glutamate in striatal astrocytes and basal ganglia excitotoxicity
-
Morales I, Rodriguez M (2012) Self-induced accumulation of glutamate in striatal astrocytes and basal ganglia excitotoxicity. Glia 60:1481-1494. doi:10.1002/glia.22368
-
(2012)
Glia
, vol.60
, pp. 1481-1494
-
-
Morales, I.1
Rodriguez, M.2
-
63
-
-
84876100906
-
Memantine for axial signs in Parkinson's disease: A randomised, double-blind, placebo-controlled pilot study
-
Moreau C, Delval A, Tiffreau V et al (2013) Memantine for axial signs in Parkinson's disease: a randomised, double-blind, placebo-controlled pilot study. J Neurol Neurosurg Psychiatry 84:552-555. doi:10.1136/jnnp-2012-303182
-
(2013)
J Neurol Neurosurg Psychiatry
, vol.84
, pp. 552-555
-
-
Moreau, C.1
Delval, A.2
Tiffreau, V.3
-
64
-
-
77950958966
-
Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys
-
Morin N, Grégoire L, Gomez-Mancilla B et al (2010) Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys. Neuropharmacology 58:981-986. doi:10.1016/j.neuropharm.2009.12.024
-
(2010)
Neuropharmacology
, vol.58
, pp. 981-986
-
-
Morin, N.1
Grégoire, L.2
Gomez-Mancilla, B.3
-
65
-
-
22244467128
-
Efficacy of budipine and placebo in untreated patients with Parkinson's disease
-
Müller T, Kuhn W, Przuntek H (2005) Efficacy of budipine and placebo in untreated patients with Parkinson's disease. J Neural Transm 112:1015-1023. doi:10.1007/s00702-004-0247-3
-
(2005)
J Neural Transm
, vol.112
, pp. 1015-1023
-
-
Müller, T.1
Kuhn, W.2
Przuntek, H.3
-
66
-
-
0035996544
-
Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease
-
Murray TK, Messenger MJ, Ward MA et al (2002) Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease. Pharmacol Biochem Behav 73:455-466
-
(2002)
Pharmacol Biochem Behav
, vol.73
, pp. 455-466
-
-
Murray, T.K.1
Messenger, M.J.2
Ward, M.A.3
-
67
-
-
84862974980
-
A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics
-
Nguyen D, Alavi MV, Kim K-Y et al (2011) A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics. Cell Death Dis 2:e240. doi:10.1038/cddis.2011.117
-
(2011)
Cell Death Dis
, vol.2
-
-
Nguyen, D.1
Alavi, M.V.2
Kim, K.-Y.3
-
68
-
-
57649178442
-
Oxidative stress and energy crises in neuronal dysfunction
-
Nicholls DG (2008) Oxidative stress and energy crises in neuronal dysfunction. Ann N Y Acad Sci 1147:53-60. doi:10.1196/annals.1427.002
-
(2008)
Ann N Y Acad Sci
, vol.1147
, pp. 53-60
-
-
Nicholls, D.G.1
-
69
-
-
77949516412
-
Metabotropic glutamate receptors: Physiology, pharmacology, and disease
-
Niswender CM, Conn PJ (2010) Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu Rev Pharmacol Toxicol 50:295-322. doi:10.1146/annurev.pharmtox.011008.145533
-
(2010)
Annu Rev Pharmacol Toxicol
, vol.50
, pp. 295-322
-
-
Niswender, C.M.1
Conn, P.J.2
-
70
-
-
84921447194
-
Possible contribution of microglial glutamate receptors to inflammatory response upon neurodegenerative diseases
-
Noda M, BeppuK (2013) Possible contribution of microglial glutamate receptors to inflammatory response upon neurodegenerative diseases. J Neurol Dis 1:131. doi:10.4172/2329-6895.1000131
-
(2013)
J Neurol Dis
, vol.1
, pp. 131
-
-
Noda, M.1
Beppu, K.2
-
71
-
-
57049160908
-
Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and Parkinsonism
-
Nutt JG, Gunzler SA, Kirchhoff T et al (2008) Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and Parkinsonism. Mov Disord 23:1860-1866. doi:10.1002/mds.22169
-
(2008)
Mov Disord
, vol.23
, pp. 1860-1866
-
-
Nutt, J.G.1
Gunzler, S.A.2
Kirchhoff, T.3
-
72
-
-
23844436731
-
MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats
-
Ossowska K, Konieczny J, Wolfarth S, Pilc A (2005) MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats. Neuropharmacology 49:447-455. doi:10.1016/j.neuro pharm.2005.04.002
-
(2005)
Neuropharmacology
, vol.49
, pp. 447-455
-
-
Ossowska, K.1
Konieczny, J.2
Wolfarth, S.3
Pilc, A.4
-
73
-
-
77958523402
-
Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition
-
Paillé V, Picconi B, Bagetta V et al (2010) Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition. J Neurosci 30:14182-14193. doi:10.1523/JNEUROSCI.2149-10.2010
-
(2010)
J Neurosci
, vol.30
, pp. 14182-14193
-
-
Paillé, V.1
Picconi, B.2
Bagetta, V.3
-
74
-
-
84878254691
-
NMDA receptor subunit diversity: Impact on receptor properties, synaptic plasticity and disease
-
Paoletti P, Bellone C, Zhou Q (2013) NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci 14:383-400. doi:10.1038/nrn3504
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 383-400
-
-
Paoletti, P.1
Bellone, C.2
Zhou, Q.3
-
75
-
-
0028080101
-
Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization
-
Pellerin L, Magistretti PJ (1994) Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci USA 91:10625-10629
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10625-10629
-
-
Pellerin, L.1
Magistretti, P.J.2
-
77
-
-
84858121110
-
Synaptic dysfunction in Parkinson's disease
-
Picconi B, Piccoli G, Calabresi P (2012) Synaptic dysfunction in Parkinson's disease. Adv Exp Med Biol 970:553-572. doi:10.1007/978-3-7091-0932-8_24
-
(2012)
Adv Exp Med Biol
, vol.970
, pp. 553-572
-
-
Picconi, B.1
Piccoli, G.2
Calabresi, P.3
-
78
-
-
78649516910
-
Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy-implications for excitotoxicity
-
Price DL, Rockenstein E, Ubhi K et al (2010) Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy-implications for excitotoxicity. PLoS One 5:e14020. doi:10.1371/journal.pone.0014020
-
(2010)
PLoS One
, vol.5
-
-
Price, D.L.1
Rockenstein, E.2
Ubhi, K.3
-
79
-
-
41549104172
-
Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in an MPTP-treated monkey model of parkinsonism
-
Raju DV, Ahern TH, Shah DJ et al (2008) Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in an MPTP-treated monkey model of parkinsonism. Eur J Neurosci 27:1647-1658. doi:10.1111/j.1460-9568.2008.06136.x
-
(2008)
Eur J Neurosci
, vol.27
, pp. 1647-1658
-
-
Raju, D.V.1
Ahern, T.H.2
Shah, D.J.3
-
80
-
-
84855825060
-
Perampanel in Parkinson disease fluctuations: A double-blind randomized trial with placebo and entacapone
-
Rascol O, Barone P, Behari M et al (2012) Perampanel in Parkinson disease fluctuations: a double-blind randomized trial with placebo and entacapone. Clin Neuropharmacol 35:15-20. doi:10.1097/WNF.0b013e318241520b
-
(2012)
Clin Neuropharmacol
, vol.35
, pp. 15-20
-
-
Rascol, O.1
Barone, P.2
Behari, M.3
-
81
-
-
73549088051
-
Activity-dependent synaptic plasticity of NMDA receptors
-
Rebola N, Srikumar BN, Mulle C (2010) Activity-dependent synaptic plasticity of NMDA receptors. J Physiol 588:93-99. doi:10.1113/jphysiol.2009.179382
-
(2010)
J Physiol
, vol.588
, pp. 93-99
-
-
Rebola, N.1
Srikumar, B.N.2
Mulle, C.3
-
82
-
-
84866079656
-
Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration
-
Rodriguez-Rodriguez P, Fernandez E, Almeida A, Bolaños JP (2012) Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration. Cell Death Differ 19:1582-1589. doi:10.1038/cdd.2012.33
-
(2012)
Cell Death Differ
, vol.19
, pp. 1582-1589
-
-
Rodriguez-Rodriguez, P.1
Fernandez, E.2
Almeida, A.3
Bolaños, J.P.4
-
83
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
-
Rothstein JD, Dykes-Hoberg M, Pardo CA et al (1996) Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16:675-686
-
(1996)
Neuron
, vol.16
, pp. 675-686
-
-
Rothstein, J.D.1
Dykes-Hoberg, M.2
Pardo, C.A.3
-
84
-
-
84888874688
-
Levodopa in the treatment of Parkinson's disease: Current status and new developments
-
Salat D, Tolosa E (2013) Levodopa in the treatment of Parkinson's disease: current status and new developments. J Parkinsons Dis 3:255-269. doi:10.3233/JPD-130186
-
(2013)
J Parkinsons Dis
, vol.3
, pp. 255-269
-
-
Salat, D.1
Tolosa, E.2
-
85
-
-
84858150213
-
Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser(19)
-
Salvatore MF, Davis RW, Arnold JC, Chotibut T (2012) Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser(19). Exp Neurol 234:428-436. doi:10.1016/j.expneurol.2012. 01.012
-
(2012)
Exp Neurol
, vol.234
, pp. 428-436
-
-
Salvatore, M.F.1
Davis, R.W.2
Arnold, J.C.3
Chotibut, T.4
-
87
-
-
0031792791
-
Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity
-
Sattler R, Charlton MP, Hafner M, Tymianski M (1998) Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity. J Neurochem 71:2349-2364
-
(1998)
J Neurochem
, vol.71
, pp. 2349-2364
-
-
Sattler, R.1
Charlton, M.P.2
Hafner, M.3
Tymianski, M.4
-
88
-
-
79251522860
-
Amantadine for dyskinesias in Parkinson's disease: A randomized controlled trial
-
Sawada H, Oeda T, Kuno S et al (2010) Amantadine for dyskinesias in Parkinson's disease: a randomized controlled trial. PLoS One 5:e15298. doi:10.1371/journal.pone.0015298
-
(2010)
PLoS One
, vol.5
-
-
Sawada, H.1
Oeda, T.2
Kuno, S.3
-
89
-
-
0035957065
-
A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease
-
Shoulson I, Penney J, McDermott M et al (2001) A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease. Neurology 56:455-462
-
(2001)
Neurology
, vol.56
, pp. 455-462
-
-
Shoulson, I.1
Penney, J.2
McDermott, M.3
-
90
-
-
79953325908
-
Protective effect of L-kynurenine and probenecid on 6-hydroxydopamine-induced striatal toxicity in rats: Implications of modulating kynurenate as a protective strategy
-
Silva-Adaya D, Pérez-De La Cruz V, Villeda-Herná'ndez J et al (2011) Protective effect of L-kynurenine and probenecid on 6-hydroxydopamine-induced striatal toxicity in rats: implications of modulating kynurenate as a protective strategy. Neurotoxicol Teratol 33:303-312. doi:10.1016/j.ntt.2010.10.002
-
(2011)
Neurotoxicol Teratol
, vol.33
, pp. 303-312
-
-
Silva-Adaya, D.1
Pérez-De La Cruz, V.2
Villeda-Herná'ndez, J.3
-
92
-
-
84887620872
-
AFQ056 in Parkinson patients with levodopa-induced dyskinesia: 13-week, randomized, dose-finding study
-
Stocchi F, Rascol O, Destee A et al (2013) AFQ056 in Parkinson patients with levodopa-induced dyskinesia: 13-week, randomized, dose-finding study. Mov Disord. doi:10.1002/mds.25561
-
(2013)
Mov Disord
-
-
Stocchi, F.1
Rascol, O.2
Destee, A.3
-
93
-
-
0036128148
-
Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes
-
Tavares RG, Tasca CI, Santos CES et al (2002) Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes. Neurochem Int 40:621-627
-
(2002)
Neurochem Int
, vol.40
, pp. 621-627
-
-
Tavares, R.G.1
Tasca, C.I.2
Santos, C.E.S.3
-
94
-
-
0026082060
-
Protection of substantia nigra from MPP ? neurotoxicity by N-methyl-D-aspartate antagonists
-
Turski L, Bressler K, Rettig KJ et al (1991) Protection of substantia nigra from MPP ? neurotoxicity by N-methyl-D-aspartate antagonists. Nature 349:414-418. doi:10.1038/349414a0
-
(1991)
Nature
, vol.349
, pp. 414-418
-
-
Turski, L.1
Bressler, K.2
Rettig, K.J.3
-
95
-
-
77949495194
-
NMDA antagonist memantine improves levodopa-induced dyskinesias and "onoff" phenomena in Parkinson's disease
-
Varanese S, Howard J, Di Rocco A (2010) NMDA antagonist memantine improves levodopa-induced dyskinesias and "onoff" phenomena in Parkinson's disease. Mov Disord 25:508-510. doi:10.1002/mds.22917
-
(2010)
Mov Disord
, vol.25
, pp. 508-510
-
-
Varanese, S.1
Howard, J.2
Di Rocco, A.3
-
96
-
-
84872253989
-
Unexpected improvement in levodopa-induced dyskinesia and on-off phenomena after introduction of memantine for treatment of Parkinson's disease dementia
-
Vidal E, Fukushima FB, Valle AP, Villas Boas PJF (2013) Unexpected improvement in levodopa-induced dyskinesia and on-off phenomena after introduction of memantine for treatment of Parkinson's disease dementia. J Am Geriatr Soc 61:170-172. doi:10.1111/jgs.12058
-
(2013)
J Am Geriatr Soc
, vol.61
, pp. 170-172
-
-
Vidal, E.1
Fukushima, F.B.2
Valle, A.P.3
Villas Boas, P.J.F.4
-
97
-
-
84885165170
-
Memantine block depends on agonist presentation at the NMDA receptor in substantia nigra pars compacta dopamine neurones
-
Wild AR, Akyol E, Brothwell SLC et al (2013) Memantine block depends on agonist presentation at the NMDA receptor in substantia nigra pars compacta dopamine neurones. Neuropharmacology 73C:138-146. doi:10.1016/j.neuropharm.2013. 05.013
-
(2013)
Neuropharmacology
, vol.73 C
, pp. 138-146
-
-
Wild, A.R.1
Akyol, E.2
Brothwell, S.L.C.3
-
98
-
-
77953184604
-
Long-term antidyskinetic efficacy of amantadine in Parkinson's disease
-
Wolf E, Seppi K, Katzenschlager R et al (2010) Long-term antidyskinetic efficacy of amantadine in Parkinson's disease. Mov Disord 25:1357-1363. doi:10.1002/mds.23034
-
(2010)
Mov Disord
, vol.25
, pp. 1357-1363
-
-
Wolf, E.1
Seppi, K.2
Katzenschlager, R.3
-
99
-
-
61849083067
-
Rotenone reduces Mg2?-dependent block of NMDA currents in substantia nigra dopamine neurons
-
Wu Y-N, Johnson SW (2009) Rotenone reduces Mg2?-dependent block of NMDA currents in substantia nigra dopamine neurons. Neurotoxicology 30:320-325. doi:10.1016/j.neuro.2009.01.002
-
(2009)
Neurotoxicology
, vol.30
, pp. 320-325
-
-
Wu, Y.-N.1
Johnson, S.W.2
-
100
-
-
84867725042
-
Mitochondrial thiols in the regulation of cell death pathways
-
Yin F, Sancheti H, Cadenas E (2012) Mitochondrial thiols in the regulation of cell death pathways. Antioxid Redox Signal 17:1714-1727. doi:10.1089/ars.2012.4639
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 1714-1727
-
-
Yin, F.1
Sancheti, H.2
Cadenas, E.3
-
101
-
-
79955675748
-
Endogenous neuroprotection in chronic neurodegenerative disorders: With particular regard to the kynurenines
-
Zá'dori D, Klivényi P, Plangá'r I et al (2011) Endogenous neuroprotection in chronic neurodegenerative disorders: with particular regard to the kynurenines. J Cell Mol Med 15:701-717. doi:10.1111/j.1582-4934.2010.01237.x
-
(2011)
J Cell Mol Med
, vol.15
, pp. 701-717
-
-
Zá'dori, D.1
Klivényi, P.2
Plangá'r, I.3
-
102
-
-
79958097582
-
Kainic Acid-induced neurotoxicity: Targeting glial responses and glia-derived cytokines
-
Zhang X-M, Zhu J (2011) Kainic Acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines. Curr Neuropharmacol 9:388-398. doi:10.2174/157015911795596540
-
(2011)
Curr Neuropharmacol
, vol.9
, pp. 388-398
-
-
Zhang, X.-M.1
Zhu, J.2
-
103
-
-
84875889310
-
NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors
-
Zhou X, Hollern D, Liao J et al (2013) NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors. Cell Death Dis 4:e560. doi:10.1038/cddis.2013.82
-
(2013)
Cell Death Dis
, vol.4
-
-
Zhou, X.1
Hollern, D.2
Liao, J.3
|