메뉴 건너뛰기




Volumn 60, Issue 7, 2000, Pages 979-988

Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation

Author keywords

1 methyl 4 phenylpyridinium; Astrocytes; Glutamate; Hydrogen peroxide; Nitric oxide; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; BUTHIONINE SULFOXIMINE; GLUTAMIC ACID; GLUTATHIONE; HYDROGEN PEROXIDE; NITRIC OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

EID: 0034308136     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00415-9     Document Type: Article
Times cited : (81)

References (50)
  • 1
    • 0002287271 scopus 로고
    • Pathology of Parkinson's disease
    • C.D. Marsden, & S. Fahn. London: Butterworth Scientific
    • Forno S. Pathology of Parkinson's disease. Marsden C.D., Fahn S. Movement Disorders, Neurology 2. 1981;21-40 Butterworth Scientific, London.
    • (1981) Movement Disorders, Neurology 2 , pp. 21-40
    • Forno, S.1
  • 2
    • 0031930771 scopus 로고    scopus 로고
    • Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease
    • Banati R.B., Daniel S.E., Blunt S.B. Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease. Mov Disord. 13:1998;221-227.
    • (1998) Mov Disord , vol.13 , pp. 221-227
    • Banati, R.B.1    Daniel, S.E.2    Blunt, S.B.3
  • 3
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner P., Olanow W.C. Oxidative stress and the pathogenesis of Parkinson's disease. Neurology. 47:(Suppl 3):1996;S161-S170.
    • (1996) Neurology , vol.47 , Issue.SUPPL. 3 , pp. 161-S170
    • Jenner, P.1    Olanow, W.C.2
  • 4
    • 0028075410 scopus 로고
    • Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
    • Sian J., Dexter D.T., Lees A.J., Daniel S., Agid Y., Javoy-Agid F., Jenner P., Marsden C.D. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol. 36:1994;348-355.
    • (1994) Ann Neurol , vol.36 , pp. 348-355
    • Sian, J.1    Dexter, D.T.2    Lees, A.J.3    Daniel, S.4    Agid, Y.5    Javoy-Agid, F.6    Jenner, P.7    Marsden, C.D.8
  • 5
    • 0025821265 scopus 로고
    • Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia
    • Dexter D.T., Carayon A., Javoy-Agid F., Agid Y., Wells F.R., Daniel S.E., Jenner P., Marsden C.D. Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain. 114:1991;1953-1975.
    • (1991) Brain , vol.114 , pp. 1953-1975
    • Dexter, D.T.1    Carayon, A.2    Javoy-Agid, F.3    Agid, Y.4    Wells, F.R.5    Daniel, S.E.6    Jenner, P.7    Marsden, C.D.8
  • 6
    • 0024321178 scopus 로고
    • A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra
    • Saggu H., Cooksey J., Dexter D., Wells F.R., Lees A., Jenner P., Marsden C.D. A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra. J Neurochem. 53:1989;692-697.
    • (1989) J Neurochem , vol.53 , pp. 692-697
    • Saggu, H.1    Cooksey, J.2    Dexter, D.3    Wells, F.R.4    Lees, A.5    Jenner, P.6    Marsden, C.D.7
  • 8
    • 0030805622 scopus 로고    scopus 로고
    • A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
    • Alam Z.I., Daniel S.E., Lees A.J., Marsden C.D., Jenner P., Halliwell B. A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J Neurochem. 69:1997;1326-1329.
    • (1997) J Neurochem , vol.69 , pp. 1326-1329
    • Alam, Z.I.1    Daniel, S.E.2    Lees, A.J.3    Marsden, C.D.4    Jenner, P.5    Halliwell, B.6
  • 9
    • 0000232034 scopus 로고
    • A marker of oxyradical-mediated DNA damage (8-hydroxy-2′-deoxyguanosine) is increased in nigro-striatum in Parkinson's disease brain
    • Sanchez-Ramos J.R., Overvik E., Ames B.N. A marker of oxyradical-mediated DNA damage (8-hydroxy-2′-deoxyguanosine) is increased in nigro-striatum in Parkinson's disease brain. Neurodegeneration. 3:1994;197-204.
    • (1994) Neurodegeneration , vol.3 , pp. 197-204
    • Sanchez-Ramos, J.R.1    Overvik, E.2    Ames, B.N.3
  • 11
    • 0028176592 scopus 로고
    • An immunohistochemical study on α-ketoglutarate dehydrogenase complex in Parkinson's disease
    • Mizuno Y., Matuda S., Yoshino H., Mori H., Hattori N., Ikebe S. An immunohistochemical study on α-ketoglutarate dehydrogenase complex in Parkinson's disease. Ann Neurol. 35:1994;204-210.
    • (1994) Ann Neurol , vol.35 , pp. 204-210
    • Mizuno, Y.1    Matuda, S.2    Yoshino, H.3    Mori, H.4    Hattori, N.5    Ikebe, S.6
  • 13
    • 0027204154 scopus 로고
    • Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate
    • Beal M.F., Brouillet E., Jenkins B., Henshaw R., Rosen B., Hyman B.T. Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate. J Neurochem. 61:1993;1147-1150.
    • (1993) J Neurochem , vol.61 , pp. 1147-1150
    • Beal, M.F.1    Brouillet, E.2    Jenkins, B.3    Henshaw, R.4    Rosen, B.5    Hyman, B.T.6
  • 14
    • 0030478699 scopus 로고    scopus 로고
    • Neurodegenerative disorders: Clues from glutamate and energy metabolism
    • Ikonomidou C., Turski L. Neurodegenerative disorders Clues from glutamate and energy metabolism . Crit Rev Neurobiol. 10:1996;239-263.
    • (1996) Crit Rev Neurobiol , vol.10 , pp. 239-263
    • Ikonomidou, C.1    Turski, L.2
  • 15
    • 0031882897 scopus 로고    scopus 로고
    • Nitric oxide causes glutamate release from brain synaptosomes
    • McNaught K. StP, Brown G.C. Nitric oxide causes glutamate release from brain synaptosomes. J Neurochem. 70:1998;1541-1546.
    • (1998) J Neurochem , vol.70 , pp. 1541-1546
    • McNaught, K.S.1    Brown, G.C.2
  • 16
    • 0029988384 scopus 로고    scopus 로고
    • Glutathione efflux from cultured astrocytes
    • Sagara J., Makino N., Bannai S. Glutathione efflux from cultured astrocytes. J Neurochem. 66:1996;1876-1881.
    • (1996) J Neurochem , vol.66 , pp. 1876-1881
    • Sagara, J.1    Makino, N.2    Bannai, S.3
  • 17
    • 0028726417 scopus 로고
    • Iron immunohistochemistry of the substantia nigra in Parkinson's disease
    • Morris C.M., Edwardson J.A. Iron immunohistochemistry of the substantia nigra in Parkinson's disease. Neurodegeneration. 3:1994;277-282.
    • (1994) Neurodegeneration , vol.3 , pp. 277-282
    • Morris, C.M.1    Edwardson, J.A.2
  • 18
    • 0017864441 scopus 로고
    • Superoxide dismutase and glutathione peroxidase activities in rat brain
    • Savolainen H. Superoxide dismutase and glutathione peroxidase activities in rat brain. Res Commun Chem Pathol Pharmacol. 21:1978;173-176.
    • (1978) Res Commun Chem Pathol Pharmacol , vol.21 , pp. 173-176
    • Savolainen, H.1
  • 19
    • 0032524916 scopus 로고    scopus 로고
    • Comparison of mitochondrial respiratory-chain enzyme activities in rodent astrocytes and neurones and a human astrocytoma cell line
    • Stewart V.C., Land J.M., Clark J.B., Heales S.J.R. Comparison of mitochondrial respiratory-chain enzyme activities in rodent astrocytes and neurones and a human astrocytoma cell line. Neurosci Lett. 247:1998;201-203.
    • (1998) Neurosci Lett , vol.247 , pp. 201-203
    • Stewart, V.C.1    Land, J.M.2    Clark, J.B.3    Heales, S.J.R.4
  • 20
    • 0342399724 scopus 로고
    • Local support cells promote survival of substantia nigra dopaminergic neurons in culture
    • O'Malley E.K., Black I.B., Dreyfus C.F. Local support cells promote survival of substantia nigra dopaminergic neurons in culture. Exp Neurol. 11:1991;240-248.
    • (1991) Exp Neurol , vol.11 , pp. 240-248
    • O'Malley, E.K.1    Black, I.B.2    Dreyfus, C.F.3
  • 21
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • McGeer P.L., Itagaki S., Boyes B.E., McGeer E.G. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology. 38:1988;1285-1291.
    • (1988) Neurology , vol.38 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 22
    • 0028171374 scopus 로고
    • Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients
    • Mogi M., Harada M., Kondo T., Riederer P., Inagaki H., Minami M., Nagatsu T. Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients. Neurosci Lett. 180:1994;147-150.
    • (1994) Neurosci Lett , vol.180 , pp. 147-150
    • Mogi, M.1    Harada, M.2    Kondo, T.3    Riederer, P.4    Inagaki, H.5    Minami, M.6    Nagatsu, T.7
  • 23
    • 0028364696 scopus 로고
    • Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
    • Boka C., Anglade P., Wallach D., Javoy-Agid F., Hirsch E.C. Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci Lett. 172:1994;151-154.
    • (1994) Neurosci Lett , vol.172 , pp. 151-154
    • Boka, C.1    Anglade, P.2    Wallach, D.3    Javoy-Agid, F.4    Hirsch, E.C.5
  • 24
    • 0028145462 scopus 로고
    • Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes
    • Bolaños J.P., Peuchen S., Heales S.J., Land J.M., Clark J.B. Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J Neurochem. 63:1994;910-916.
    • (1994) J Neurochem , vol.63 , pp. 910-916
    • Bolaños, J.P.1    Peuchen, S.2    Heales, S.J.3    Land, J.M.4    Clark, J.B.5
  • 26
    • 0029818211 scopus 로고    scopus 로고
    • Glia: The not so innocent bystanders
    • Chao C.C., Hu S., Peterson P.K. Glia The not so innocent bystanders . J Neurovirol. 2:1996;234-239.
    • (1996) J Neurovirol , vol.2 , pp. 234-239
    • Chao, C.C.1    Hu, S.2    Peterson, P.K.3
  • 27
    • 0030108525 scopus 로고    scopus 로고
    • Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
    • Chao C.C., Hu S., Sheng W.S., Bu D., Bukrinsky M.I., Peterson P.K. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia. 16:1996;276-284.
    • (1996) Glia , vol.16 , pp. 276-284
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Bu, D.4    Bukrinsky, M.I.5    Peterson, P.K.6
  • 28
    • 0028089896 scopus 로고
    • Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures
    • Dawson V.L., Brahmbhatt H.P., Mong J.A., Dawson T.M. Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures. Neuropharmacology. 33:1994;1425-1430.
    • (1994) Neuropharmacology , vol.33 , pp. 1425-1430
    • Dawson, V.L.1    Brahmbhatt, H.P.2    Mong, J.A.3    Dawson, T.M.4
  • 30
    • 0031004608 scopus 로고    scopus 로고
    • The γ-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture
    • Dringen R., Kranich O., Hamprecht B. The γ-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture. Neurochem Res. 22:1997;727-733.
    • (1997) Neurochem Res , vol.22 , pp. 727-733
    • Dringen, R.1    Kranich, O.2    Hamprecht, B.3
  • 31
    • 0027421350 scopus 로고
    • Maintenance of neuronal glutathione by glial cells
    • Sagara J.I., Miura K., Bannai S. Maintenance of neuronal glutathione by glial cells. J Neurochem. 61:1993;1672-1676.
    • (1993) J Neurochem , vol.61 , pp. 1672-1676
    • Sagara, J.I.1    Miura, K.2    Bannai, S.3
  • 32
    • 0029837447 scopus 로고    scopus 로고
    • Quantification of nitrate and nitrite in extracellular fluids
    • Grisham M.B., Johnson G.G., Lancaster J.R. Quantification of nitrate and nitrite in extracellular fluids. Methods Enzymol. 268:1996;237-246.
    • (1996) Methods Enzymol , vol.268 , pp. 237-246
    • Grisham, M.B.1    Johnson, G.G.2    Lancaster, J.R.3
  • 33
    • 0029990439 scopus 로고    scopus 로고
    • Astrocytes protect neurons from hydrogen peroxide toxicity
    • Desagher S., Glowinski J., Premont J. Astrocytes protect neurons from hydrogen peroxide toxicity. J Neurosci. 16:1996;2553-2568.
    • (1996) J Neurosci , vol.16 , pp. 2553-2568
    • Desagher, S.1    Glowinski, J.2    Premont, J.3
  • 34
    • 0000068602 scopus 로고
    • l-Glutamate: UV-method with glutaminase and glutamate dehydrogenase
    • (Ed. Bergmeyer HU), Verlag Chemie GmbH, Varlagsgesellschair, Weinheim
    • l-Glutamate: UV-method with glutaminase and glutamate dehydrogenase. In: Methods of Enzymatic Analysis, Vol. 8 (Ed. Bergmeyer HU), pp. 357-363. Verlag Chemie GmbH, Varlagsgesellschair, Weinheim, 1986.
    • (1986) In: Methods of Enzymatic Analysis , vol.8 , pp. 357-363
    • Lund, P.1
  • 35
    • 0032032480 scopus 로고    scopus 로고
    • Astrocytes protect neurons from neurotoxic injury by serum glutamate
    • Ye Z.C., Sontheimer H. Astrocytes protect neurons from neurotoxic injury by serum glutamate. Glia. 22:1998;237-248.
    • (1998) Glia , vol.22 , pp. 237-248
    • Ye, Z.C.1    Sontheimer, H.2
  • 36
    • 0030687537 scopus 로고    scopus 로고
    • The role of the immune system in neurodegenerative disorders
    • McGeer E.G., McGeer P.L. The role of the immune system in neurodegenerative disorders. Mov Disord. 12:1997;855-858.
    • (1997) Mov Disord , vol.12 , pp. 855-858
    • McGeer, E.G.1    McGeer, P.L.2
  • 37
    • 0029033427 scopus 로고
    • Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration
    • Brown G.C., Bolaños J.P., Heales S.J., Clark J.B. Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration. Neurosci Lett. 193:1995;5275-5285.
    • (1995) Neurosci Lett , vol.193 , pp. 5275-5285
    • Brown, G.C.1    Bolaños, J.P.2    Heales, S.J.3    Clark, J.B.4
  • 38
    • 0030881783 scopus 로고    scopus 로고
    • Inhibition of astrocyte glutamate uptake by reactive oxygen species: Role of antioxidant enzymes
    • Sorg O., Horn T.F., Yu N., Gruol D.L., Bloom F.E. Inhibition of astrocyte glutamate uptake by reactive oxygen species Role of antioxidant enzymes . Mol Med. 3:1997;431-440.
    • (1997) Mol Med , vol.3 , pp. 431-440
    • Sorg, O.1    Horn, T.F.2    Yu, N.3    Gruol, D.L.4    Bloom, F.E.5
  • 39
    • 0026584089 scopus 로고
    • 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase
    • 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J. 281:1992;627-630.
    • (1992) Biochem J , vol.281 , pp. 627-630
    • Heinzel, B.1    John, M.2    Klatt, P.3    Böhme, E.4    Mayer, B.5
  • 40
    • 0026470180 scopus 로고
    • Generation of superoxide by purified brain nitric oxide synthase
    • Pou S., Pou W.S., Bredt D.S., Snyder S.H., Rosen G.M. Generation of superoxide by purified brain nitric oxide synthase. J Biol Chem. 267:1992;24173-24176.
    • (1992) J Biol Chem , vol.267 , pp. 24173-24176
    • Pou, S.1    Pou, W.S.2    Bredt, D.S.3    Snyder, S.H.4    Rosen, G.M.5
  • 41
    • 0024997609 scopus 로고
    • +) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
    • +) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles. Biochem Biophys Res Commun. 170:1990;1049-1055.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 1049-1055
    • Hasegawa, E.1    Takeshige, K.2    Oishi, T.3    Murai, Y.4    Minakami, S.5
  • 42
    • 0029869189 scopus 로고    scopus 로고
    • Mechanisms involved in the generation of free radicals
    • Halliwell B. Mechanisms involved in the generation of free radicals. Pathol Biol. 44:1996;6-13.
    • (1996) Pathol Biol , vol.44 , pp. 6-13
    • Halliwell, B.1
  • 43
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research therapy
    • Meister A. Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research therapy. Pharmacol Ther. 51:1991;155-194.
    • (1991) Pharmacol Ther , vol.51 , pp. 155-194
    • Meister, A.1
  • 44
    • 0030772178 scopus 로고    scopus 로고
    • Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency
    • Drukarch B., Schepens E., Jongenelen C.A., Stoof J.C., Langeveld C.H. Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency. Brian Res. 770:1997;123-130.
    • (1997) Brian Res , vol.770 , pp. 123-130
    • Drukarch, B.1    Schepens, E.2    Jongenelen, C.A.3    Stoof, J.C.4    Langeveld, C.H.5
  • 45
    • 0030852097 scopus 로고    scopus 로고
    • Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by cultured astroglial cells
    • Dringen R., Hamprecht B. Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by cultured astroglial cells. Brain Res. 759:1997;67-75.
    • (1997) Brain Res , vol.759 , pp. 67-75
    • Dringen, R.1    Hamprecht, B.2
  • 46
    • 0029670509 scopus 로고    scopus 로고
    • Thioctic acid does not restore glutathione levels or protect against the potentiation of 6-hydroxydopamine toxicity induced by glutathione depletion in rats
    • Seaton T.A., Jenner P., Marsden C.D. Thioctic acid does not restore glutathione levels or protect against the potentiation of 6-hydroxydopamine toxicity induced by glutathione depletion in rats. J Neural Transm. 103:1996;315-329.
    • (1996) J Neural Transm , vol.103 , pp. 315-329
    • Seaton, T.A.1    Jenner, P.2    Marsden, C.D.3
  • 50
    • 0032748383 scopus 로고    scopus 로고
    • Altered glial function causes neuronal death and increases neuronal susceptibility to 1-methyl-4-phenylpyridinium and 6-hydroxydopamine-induced toxicity in astrocytic/ventral mesencephalic co-cultures
    • McNaught KStP, Jenner P. Altered glial function causes neuronal death and increases neuronal susceptibility to 1-methyl-4-phenylpyridinium and 6-hydroxydopamine-induced toxicity in astrocytic/ventral mesencephalic co-cultures. J Neurochem. 73:1999;2469-2476.
    • (1999) J Neurochem , vol.73 , pp. 2469-2476
    • McNaught, K.1    Jenner, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.