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Volumn 79, Issue 8, 2014, Pages 740-749

Lithium salts - Simple but magic

Author keywords

brain; glycogen synthase kinase; heart; ischemia; kidney; lithium ions; mitochondria; stem cells

Indexed keywords

LITHIUM DERIVATIVE;

EID: 84906281899     PISSN: 00062979     EISSN: 16083040     Source Type: Journal    
DOI: 10.1134/S0006297914080021     Document Type: Review
Times cited : (27)

References (89)
  • 1
    • 78651023893 scopus 로고
    • Lithium salts in the treatment of psychotic excitement
    • 1:STN:280:DyaH1M%2FksVaqtw%3D%3D 18142718
    • Cade, J. F. (1949) Lithium salts in the treatment of psychotic excitement, Med. J. Aust.; 2, 349-352.
    • (1949) Med. J. Aust. , vol.2 , pp. 349-352
    • Cade, J.F.1
  • 2
    • 0034044008 scopus 로고    scopus 로고
    • Lithium treatment for bipolar disorder
    • 1:STN:280:DC%2BD3czosFyqsg%3D%3D 2560742 10885179
    • Mitchell, P. B.; and Hadzi-Pavlovic, D. (2000) Lithium treatment for bipolar disorder, Bull. World Health Org.; 78, 515-517.
    • (2000) Bull. World Health Org. , vol.78 , pp. 515-517
    • Mitchell, P.B.1    Hadzi-Pavlovic, D.2
  • 3
    • 0035719852 scopus 로고    scopus 로고
    • Lithium treatment at 52
    • 1:STN:280:DC%2BD387jsV2isw%3D%3D 11869750
    • Schou, M. (2001) Lithium treatment at 52, J. Affect. Disord.; 67, 21-32.
    • (2001) J. Affect. Disord. , vol.67 , pp. 21-32
    • Schou, M.1
  • 4
    • 78650176720 scopus 로고    scopus 로고
    • Efficacy of antimanic treatments: Meta-analysis of randomized, controlled trials
    • 1:CAS:528:DC%2BC3cXhsFGhtbbI 3055677 20980991
    • Yildiz, A.; Vieta, E.; Leucht, S.; and Baldessarini, R. J. (2011) Efficacy of antimanic treatments: meta-analysis of randomized, controlled trials, Neuropsychopharmacology, 36, 375-389.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 375-389
    • Yildiz, A.1    Vieta, E.2    Leucht, S.3    Baldessarini, R.J.4
  • 5
    • 33749995784 scopus 로고    scopus 로고
    • Decreased risk of suicides and attempts during long-term lithium treatment: A meta-analytic review
    • 1:CAS:528:DC%2BD28Xhtlans7vP 17042835
    • Baldessarini, R. J.; Tondo, L.; Davis, P.; Pompili, M.; Goodwin, F. K.; and Hennen, J. (2006) Decreased risk of suicides and attempts during long-term lithium treatment: a meta-analytic review, Bipolar Disord.; 8, 625-639.
    • (2006) Bipolar Disord. , vol.8 , pp. 625-639
    • Baldessarini, R.J.1    Tondo, L.2    Davis, P.3    Pompili, M.4    Goodwin, F.K.5    Hennen, J.6
  • 6
    • 0024341795 scopus 로고
    • Neural and developmental actions of lithium: A unifying hypothesis
    • 1:CAS:528:DyaK3cXntQ%3D%3D 2553271
    • Berridge, M. J.; Downes, C. P.; and Hanley, M. R. (1989) Neural and developmental actions of lithium: a unifying hypothesis, Cell, 59, 411-419.
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 7
    • 12344329222 scopus 로고    scopus 로고
    • Lithium and bipolar mood disorder: The inositol-depletion hypothesis revisited
    • 1:CAS:528:DC%2BD2cXhtFeisL3L 15558078
    • Harwood, A. J. (2005) Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited, Mol. Psychiatry, 10, 117-126.
    • (2005) Mol. Psychiatry , vol.10 , pp. 117-126
    • Harwood, A.J.1
  • 8
    • 13644268949 scopus 로고    scopus 로고
    • Bipolar disorder and myoinositol: A review of the magnetic resonance spectroscopy findings
    • 1:CAS:528:DC%2BD2MXitVGntL8%3D 15654927
    • Silverstone, P. H.; McGrath, B. M.; and Kim, H. (2005) Bipolar disorder and myoinositol: a review of the magnetic resonance spectroscopy findings, Bipolar Disord.; 7, 1-10.
    • (2005) Bipolar Disord. , vol.7 , pp. 1-10
    • Silverstone, P.H.1    McGrath, B.M.2    Kim, H.3
  • 9
    • 0035029426 scopus 로고    scopus 로고
    • Molecular targets of lithium action
    • 1:CAS:528:DC%2BD3MXjsVaqtL8%3D 11264477
    • Phiel, C. J.; and Klein, P. S. (2001) Molecular targets of lithium action, Annu. Rev. Pharmacol. Toxicol.; 41, 789-813.
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 789-813
    • Phiel, C.J.1    Klein, P.S.2
  • 10
    • 0015242494 scopus 로고
    • Reduced brain inositol in lithium-treated rats
    • 1:CAS:528:DyaE38XlsVyiug%3D%3D 5288124
    • Allison, J. H.; and Stewart, M. A. (1971) Reduced brain inositol in lithium-treated rats, Nat. New Biol.; 233, 267-268.
    • (1971) Nat. New Biol. , vol.233 , pp. 267-268
    • Allison, J.H.1    Stewart, M.A.2
  • 11
    • 84859150204 scopus 로고    scopus 로고
    • Determination of the lithium binding site in inositol monophosphatase, the putative target for lithium therapy, by magic-angle-spinning solid-state NMR
    • 1:CAS:528:DC%2BC38Xjt1SqsrY%3D 22384802
    • Haimovich, A.; Eliav, U.; and Goldbourt, A. (2012) Determination of the lithium binding site in inositol monophosphatase, the putative target for lithium therapy, by magic-angle-spinning solid-state NMR, J. Am. Chem. Soc.; 134, 5647-5651.
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 5647-5651
    • Haimovich, A.1    Eliav, U.2    Goldbourt, A.3
  • 12
    • 0024453294 scopus 로고
    • Inositol phosphates and cell signaling
    • 1:CAS:528:DyaL1MXls12ntb4%3D 2550825
    • Berridge, M. J.; and Irvine, R. F. (1989) Inositol phosphates and cell signaling, Nature, 341, 197-205.
    • (1989) Nature , vol.341 , pp. 197-205
    • Berridge, M.J.1    Irvine, R.F.2
  • 13
    • 0036220487 scopus 로고    scopus 로고
    • PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers
    • 1:CAS:528:DC%2BD38XivFejs7o%3D 11986995
    • Manji, H. K.; and Chen, G. (2002) PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers, Mol. Psychiatry, 7, S46-56.
    • (2002) Mol. Psychiatry , vol.7 , pp. 46-56
    • Manji, H.K.1    Chen, G.2
  • 14
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • 1:CAS:528:DyaK28XkvFyksLY%3D 38692 8710892
    • Klein, P. S.; and Melton, D. A. (1996) A molecular mechanism for the effect of lithium on development, Proc. Natl. Acad. Sci. USA, 93, 8455-8459.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 15
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells
    • 1:CAS:528:DyaK28XnsFKjt7o%3D 8994831
    • Stambolic, V.; Ruel, L.; and Woodgett, J. R. (1996) Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells, Curr. Biol.; 6, 1664-1668.
    • (1996) Curr. Biol. , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 16
    • 0027515127 scopus 로고
    • Inactivation of glycogen synthase kinase-3β by phosphorylation: New kinase connections in insulin and growth factor signaling
    • 1:CAS:528:DyaK2cXks1ehtw%3D%3D 1137648 8250835
    • Sutherland, C.; Leighton, I. A.; and Cohen, P. (1993) Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth factor signaling, Biochem. J.; 296 (Pt. 1), 15-19.
    • (1993) Biochem. J. , vol.296 , Issue.PART. 1 , pp. 15-19
    • Sutherland, C.1    Leighton, I.A.2    Cohen, P.3
  • 17
    • 34247865533 scopus 로고    scopus 로고
    • A chaperone-dependent GSK3β transitional intermediate mediates activation-loop autophosphorylation
    • 1:CAS:528:DC%2BD28Xht1yltrzE 17188038
    • Lochhead, P. A.; Kinstrie, R.; Sibbet, G.; Rawjee, T.; Morrice, N.; and Cleghon, V. (2006) A chaperone-dependent GSK3β transitional intermediate mediates activation-loop autophosphorylation, Mol. Cell, 24, 627-633.
    • (2006) Mol. Cell , vol.24 , pp. 627-633
    • Lochhead, P.A.1    Kinstrie, R.2    Sibbet, G.3    Rawjee, T.4    Morrice, N.5    Cleghon, V.6
  • 18
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • 1:CAS:528:DC%2BD3sXivFWhtbc%3D 3006448 12615961
    • Doble, B. W.; and Woodgett, J. R. (2003) GSK-3: tricks of the trade for a multi-tasking kinase, J. Cell Sci.; 116, 1175-1186.
    • (2003) J. Cell Sci. , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 19
    • 0034805180 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
    • 1:CAS:528:DC%2BD3MXls1ansA%3D%3D 11162580
    • Ryves, W. J.; and Harwood, A. J. (2001) Lithium inhibits glycogen synthase kinase-3 by competition for magnesium, Biochem. Biophys. Res. Commun.; 280, 720-725.
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 720-725
    • Ryves, W.J.1    Harwood, A.J.2
  • 20
    • 77957019846 scopus 로고    scopus 로고
    • Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders
    • 1:CAS:528:DC%2BC3cXht1Wjtb3M 3167234 20705090
    • Chiu, C. T.; and Chuang, D. M. (2010) Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders, Pharmacol. Ther.; 128, 281-304.
    • (2010) Pharmacol. Ther. , vol.128 , pp. 281-304
    • Chiu, C.T.1    Chuang, D.M.2
  • 21
    • 0036122349 scopus 로고    scopus 로고
    • Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A
    • 1:CAS:528:DC%2BD38XhvVWrs70%3D 11897496
    • Mora, A.; Sabio, G.; Risco, A. M.; Cuenda, A.; Alonso, J. C.; Soler, G.; and Centeno, F. (2002) Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A, Cell Signal.; 14, 557-562.
    • (2002) Cell Signal. , vol.14 , pp. 557-562
    • Mora, A.1    Sabio, G.2    Risco, A.M.3    Cuenda, A.4    Alonso, J.C.5    Soler, G.6    Centeno, F.7
  • 23
    • 0042357237 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
    • 1:CAS:528:DC%2BD3sXms1als78%3D 12796505
    • Zhang, F.; Phiel, C. J.; Spece, L.; Gurvich, N.; and Klein, P. S. (2003) Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3, J. Biol. Chem.; 278, 33067-33077.
    • (2003) J. Biol. Chem. , vol.278 , pp. 33067-33077
    • Zhang, F.1    Phiel, C.J.2    Spece, L.3    Gurvich, N.4    Klein, P.S.5
  • 24
    • 84856702223 scopus 로고    scopus 로고
    • Inhibition of GSK3 by lithium, from single molecules to signaling networks
    • 1:CAS:528:DC%2BC38Xjt1KksL4%3D 3282483 22363263
    • Freland, L.; and Beaulieu, J. M. (2012) Inhibition of GSK3 by lithium, from single molecules to signaling networks, Front. Mol. Neurosci.; 5, 14.
    • (2012) Front. Mol. Neurosci. , vol.5 , pp. 14
    • Freland, L.1    Beaulieu, J.M.2
  • 26
    • 1842787936 scopus 로고    scopus 로고
    • Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
    • 1:CAS:528:DC%2BD2cXjsFCisbg%3D 387380 15044694
    • Beaulieu, J. M.; Sotnikova, T. D.; Yao, W. D.; Kockeritz, L.; Woodgett, J. R.; Gainetdinov, R. R.; and Caron, M. G. (2004) Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade, Proc. Natl. Acad. Sci. USA, 101, 5099-5104.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 5099-5104
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Yao, W.D.3    Kockeritz, L.4    Woodgett, J.R.5    Gainetdinov, R.R.6    Caron, M.G.7
  • 27
    • 84886096735 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 substrates in mood disorders and schizophrenia
    • 1:CAS:528:DC%2BC3sXhs1Wnsr3M 23796137
    • Cole, A. R. (2013) Glycogen synthase kinase 3 substrates in mood disorders and schizophrenia, FEBS J.; 280, 5213-5227.
    • (2013) FEBS J. , vol.280 , pp. 5213-5227
    • Cole, A.R.1
  • 28
    • 0032947795 scopus 로고    scopus 로고
    • Anti-bipolar therapy: Mechanism of action of lithium
    • 1:CAS:528:DC%2BD3cXlvVWltr4%3D 10208444
    • Jope, R. S. (1999) Anti-bipolar therapy: mechanism of action of lithium, Mol. Psychiatry, 4, 117-128.
    • (1999) Mol. Psychiatry , vol.4 , pp. 117-128
    • Jope, R.S.1
  • 29
    • 84876930720 scopus 로고    scopus 로고
    • Potential mechanisms of action of lithium in bipolar disorder. Current understanding
    • 23371914
    • Malhi, G. S.; Tanious, M.; Das, P.; Coulston, C. M.; and Berk, M. (2013) Potential mechanisms of action of lithium in bipolar disorder. Current understanding, CNS Drugs, 27, 135-153.
    • (2013) CNS Drugs , vol.27 , pp. 135-153
    • Malhi, G.S.1    Tanious, M.2    Das, P.3    Coulston, C.M.4    Berk, M.5
  • 30
    • 0032493304 scopus 로고    scopus 로고
    • Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex
    • Dixon, J. F.; and Hokin, L. E. (1998) Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex, Proc. Natl. Acad. Sci. USA, 7, 8363-8368.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.7 , pp. 8363-8368
    • Dixon, J.F.1    Hokin, L.E.2
  • 31
    • 0029671363 scopus 로고    scopus 로고
    • Lithium blocks 45Ca2+ uptake into platelets in bipolar affective disorder and controls
    • 1:CAS:528:DyaK28Xhs1Sjt7g%3D 8867516
    • Berk, M.; Kirchmann, N. H.; and Butkow, N. (1996) Lithium blocks 45Ca2+ uptake into platelets in bipolar affective disorder and controls, Clin. Neuropharmacol.; 19, 48-51.
    • (1996) Clin. Neuropharmacol. , vol.19 , pp. 48-51
    • Berk, M.1    Kirchmann, N.H.2    Butkow, N.3
  • 32
    • 84905256050 scopus 로고    scopus 로고
    • Molecular actions and clinical pharmacogenetics of lithium therapy
    • doi: 10.1016/j.pbb.2014.02.004
    • Can, A.; Schulze, T. G.; and Gould, T. D. (2014) Molecular actions and clinical pharmacogenetics of lithium therapy, Pharmacol. Biochem. Behav.; doi: 10.1016/j.pbb.2014.02.004.
    • (2014) Pharmacol. Biochem. Behav.
    • Can, A.1    Schulze T., .G.2    Gould T., .D.3
  • 33
    • 84997860352 scopus 로고    scopus 로고
    • Lithium: The pharmacodynamic actions of the amazing ion
    • 1:CAS:528:DC%2BC3sXhtFCmsL7P 3805456 24167688
    • Brown, K. M.; and Tracy, D. K. (2013) Lithium: the pharmacodynamic actions of the amazing ion, Ther. Adv. Psychopharmacol.; 3, 163-176.
    • (2013) Ther. Adv. Psychopharmacol. , vol.3 , pp. 163-176
    • Brown, K.M.1    Tracy, D.K.2
  • 34
    • 0031690726 scopus 로고    scopus 로고
    • Monoamine dysfunction and the pathophysiology and treatment of depression
    • 1:CAS:528:DyaK1cXntFSgtbc%3D 9818625
    • Charney, D. S. (1998) Monoamine dysfunction and the pathophysiology and treatment of depression, J. Clin. Psychiatry, 59, 11-14.
    • (1998) J. Clin. Psychiatry , vol.59 , pp. 11-14
    • Charney, D.S.1
  • 35
    • 3242761438 scopus 로고    scopus 로고
    • In vivo regulation of glycogen synthase kinase-3β (gsk3β) by serotoninergic activity in mouse brain
    • 1:CAS:528:DC%2BD2cXlvVSjsb8%3D 1986663 15039769
    • Li, X.; Zhu, W.; Roh, M. S.; Friedman, A. B.; Rosborough, K.; and Jope, R. S. (2004) In vivo regulation of glycogen synthase kinase-3β (gsk3β) by serotoninergic activity in mouse brain, Neuropsychopharmacology, 29, 1426-1431.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1426-1431
    • Li, X.1    Zhu, W.2    Roh, M.S.3    Friedman, A.B.4    Rosborough, K.5    Jope, R.S.6
  • 36
    • 0028836585 scopus 로고
    • Li+ stimulates ATP-regulated dopamine uptake in PC12 cells
    • 1:CAS:528:DyaK2MXjvFehsrg%3D 7753392
    • Dunigan, C. D.; and Shamoo, A. E. (1995) Li+ stimulates ATP-regulated dopamine uptake in PC12 cells, Neuroscience, 65, 1-4.
    • (1995) Neuroscience , vol.65 , pp. 1-4
    • Dunigan, C.D.1    Shamoo, A.E.2
  • 37
    • 70749090026 scopus 로고    scopus 로고
    • Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotoninergic raphe neurons
    • 1:CAS:528:DC%2BD1MXhsV2murzK 19840776
    • Scheuch, K.; Holtje, M.; Budde, H.; Lautenschlager, M.; Heinz, A.; Ahnert-Hilger, G.; and Priller, J. (2010) Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotoninergic raphe neurons, Brain Res.; 1307, 14-21.
    • (2010) Brain Res. , vol.1307 , pp. 14-21
    • Scheuch, K.1    Holtje, M.2    Budde, H.3    Lautenschlager, M.4    Heinz, A.5    Ahnert-Hilger, G.6    Priller, J.7
  • 38
    • 0030748388 scopus 로고    scopus 로고
    • Regulation of central serotonin transporters by chronic lithium: An autoradiographic study
    • 1:CAS:528:DyaK2sXlt1Wrtbk%3D 9268068
    • Carli, M.; and Reader, T. A. (1997) Regulation of central serotonin transporters by chronic lithium: an autoradiographic study, Synapse, 27, 83-89.
    • (1997) Synapse , vol.27 , pp. 83-89
    • Carli, M.1    Reader, T.A.2
  • 40
    • 0032827466 scopus 로고    scopus 로고
    • Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
    • 1:CAS:528:DyaK1MXmsVWgsL0%3D 10509176
    • Manji, H. K.; Moore, G. J.; and Chen, G. (1999) Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? Biol. Psychiatry, 46, 929-940.
    • (1999) Biol. Psychiatry , vol.46 , pp. 929-940
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 41
    • 0042574206 scopus 로고    scopus 로고
    • Lithium reduced n-methyl-D-aspartate receptor subunit 2a tyrosine phosphorylation and its interactions with src and fyn mediated by psd-95 in rat hippocampus following cerebral ischemia
    • 1:CAS:528:DC%2BD3sXmsVejs7w%3D 12932824
    • Ma, J.; and Zhang, G. Y. (2003) Lithium reduced n-methyl-D-aspartate receptor subunit 2a tyrosine phosphorylation and its interactions with src and fyn mediated by psd-95 in rat hippocampus following cerebral ischemia, Neurosci. Lett.; 348, 185-189.
    • (2003) Neurosci. Lett. , vol.348 , pp. 185-189
    • Ma, J.1    Zhang, G.Y.2
  • 42
    • 0037967151 scopus 로고    scopus 로고
    • Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death
    • 1:CAS:528:DC%2BD3sXjtFGmu7Y%3D 12677021
    • Xu, J.; Culman, J.; Blume, A.; Brecht, S.; and Gohlke, P. (2003) Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death, Stroke, 34, 1287-1292.
    • (2003) Stroke , vol.34 , pp. 1287-1292
    • Xu, J.1    Culman, J.2    Blume, A.3    Brecht, S.4    Gohlke, P.5
  • 43
    • 36348970682 scopus 로고    scopus 로고
    • Lithium reduces ischemia-induced hippocampal ca1 damage and behavioral deficits in gerbils
    • 1:CAS:528:DC%2BD2sXhtlyrs7vF 18028886
    • Bian, Q.; Shi, T.; Chuang, D. M.; and Qian, Y. (2007) Lithium reduces ischemia-induced hippocampal ca1 damage and behavioral deficits in gerbils, Brain Res.; 1184, 270-276.
    • (2007) Brain Res. , vol.1184 , pp. 270-276
    • Bian, Q.1    Shi, T.2    Chuang, D.M.3    Qian, Y.4
  • 44
    • 0033587742 scopus 로고    scopus 로고
    • Lithium activates the serine/threonine kinase akt-1 and suppresses glutamate-induced inhibition of akt-1 activity in neurons
    • 1:CAS:528:DyaK1MXkslOktbk%3D 17587 10411946
    • Chalecka-Franaszek, E.; and Chuang, D. M. (1999) Lithium activates the serine/threonine kinase akt-1 and suppresses glutamate-induced inhibition of akt-1 activity in neurons, Proc. Natl. Acad. Sci. USA, 96, 8745-8750.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8745-8750
    • Chalecka-Franaszek, E.1    Chuang, D.M.2
  • 45
    • 13244257028 scopus 로고    scopus 로고
    • Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: Protection by mood stabilizers and imipramine
    • 1:CAS:528:DC%2BD2MXhtV2nt7Y%3D 15691529
    • Roh, M. S.; Eom, T. Y.; Zmijewska, A. A.; De Sarno, P.; Roth, K. A.; and Jope, R. S. (2005) Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine, Biol. Psychiatry, 57, 278-286.
    • (2005) Biol. Psychiatry , vol.57 , pp. 278-286
    • Roh, M.S.1    Eom, T.Y.2    Zmijewska, A.A.3    De Sarno, P.4    Roth, K.A.5    Jope, R.S.6
  • 47
    • 77957220638 scopus 로고    scopus 로고
    • Roles of phospho-gsk-3β in myocardial protection afforded by activation of the mitochondrial K ATP channel
    • 1:CAS:528:DC%2BC3cXht1Cgt7nI 20692265
    • Terashima, Y.; Sato, T.; Yano, T.; Maas, O.; Itoh, T.; Miki, T.; Tanno, M.; Kuno, A.; Shimamoto, K.; and Miura, T. (2010) Roles of phospho-gsk-3β in myocardial protection afforded by activation of the mitochondrial K ATP channel, J. Mol. Cell Cardiol.; 49, 762-770.
    • (2010) J. Mol. Cell Cardiol. , vol.49 , pp. 762-770
    • Terashima, Y.1    Sato, T.2    Yano, T.3    Maas, O.4    Itoh, T.5    Miki, T.6    Tanno, M.7    Kuno, A.8    Shimamoto, K.9    Miura, T.10
  • 48
    • 53449085681 scopus 로고    scopus 로고
    • Preconditioning with acute and chronic lithium administration reduces ischemia/reperfusion injury mediated by cyclooxygenase not nitric oxide synthase pathway in isolated rat heart
    • 1:CAS:528:DC%2BD1cXht1KmtbrL 18789320
    • Faghihi, M.; Mirershadi, F.; Dehpour, A. R.; and Bazargan, M. (2008) Preconditioning with acute and chronic lithium administration reduces ischemia/reperfusion injury mediated by cyclooxygenase not nitric oxide synthase pathway in isolated rat heart, Eur. J. Pharmacol.; 597, 57-63.
    • (2008) Eur. J. Pharmacol. , vol.597 , pp. 57-63
    • Faghihi, M.1    Mirershadi, F.2    Dehpour, A.R.3    Bazargan, M.4
  • 49
    • 84888632480 scopus 로고    scopus 로고
    • Gsk-3β inhibitors mimic the cardioprotection mediated by ischemic pre- and postconditioning in hypertensive rats
    • 3830772 24288674
    • Gonzalez Arbelaez, L. F.; Perez Nunez, I. A.; and Mosca, S. M. (2013) Gsk-3β inhibitors mimic the cardioprotection mediated by ischemic pre- and postconditioning in hypertensive rats, Biomed. Res. Int.; 2013, 317456.
    • (2013) Biomed. Res. Int. , vol.2013 , pp. 317456
    • Gonzalez Arbelaez, L.F.1    Perez Nunez, I.A.2    Mosca, S.M.3
  • 50
    • 77955051502 scopus 로고    scopus 로고
    • Modulation of the cardioprotective effect of ischemic preconditioning in hyperlipidaemic rat heart
    • 1:CAS:528:DC%2BC3cXptlWltL0%3D 20598682
    • Yadav, H. N.; Singh, M.; and Sharma, P. L. (2010) Modulation of the cardioprotective effect of ischemic preconditioning in hyperlipidaemic rat heart, Eur. J. Pharmacol.; 643, 78-83.
    • (2010) Eur. J. Pharmacol. , vol.643 , pp. 78-83
    • Yadav, H.N.1    Singh, M.2    Sharma, P.L.3
  • 53
    • 77957294100 scopus 로고    scopus 로고
    • Chronic lithium treatment protects the rat kidney against ischemia/reperfusion injury: The role of nitric oxide and cyclooxygenase pathways
    • 1:CAS:528:DC%2BC3cXht1CgurrP 20826134
    • Talab, S. S.; Emami, H.; Elmi, A.; Nezami, B. G.; Assa, S.; Deroee, A. F.; Daneshmand, A.; Tavangar, S. M.; and Dehpour, A. R. (2010) Chronic lithium treatment protects the rat kidney against ischemia/reperfusion injury: the role of nitric oxide and cyclooxygenase pathways, Eur. J. Pharmacol.; 647, 171-177.
    • (2010) Eur. J. Pharmacol. , vol.647 , pp. 171-177
    • Talab, S.S.1    Emami, H.2    Elmi, A.3    Nezami, B.G.4    Assa, S.5    Deroee, A.F.6    Daneshmand, A.7    Tavangar, S.M.8    Dehpour, A.R.9
  • 54
    • 84879836895 scopus 로고    scopus 로고
    • Nephroprotective effect of gsk-3β inhibition by lithium ions and δ-opioid receptor agonist dalargin on gentamicin-induced nephrotoxicity
    • 1:CAS:528:DC%2BC3sXpsV2qtL0%3D 23651617
    • Plotnikov, E. Y.; Grebenchikov, O. A.; Babenko, V. A.; Pevzner, I. B.; Zorova, L. D.; Likhvantsev, V. V.; and Zorov, D. B. (2013) Nephroprotective effect of gsk-3β inhibition by lithium ions and δ-opioid receptor agonist dalargin on gentamicin-induced nephrotoxicity, Toxicol. Lett.; 220, 303-308.
    • (2013) Toxicol. Lett. , vol.220 , pp. 303-308
    • Plotnikov, E.Y.1    Grebenchikov, O.A.2    Babenko, V.A.3    Pevzner, I.B.4    Zorova, L.D.5    Likhvantsev, V.V.6    Zorov, D.B.7
  • 55
    • 70350337981 scopus 로고    scopus 로고
    • Inhibiting glycogen synthase kinase-3 reduces endotoxaemic acute renal failure by down-regulating inflammation and renal cell apoptosis
    • 1:CAS:528:DC%2BD1MXhtVChu7bK 2737659 19508392
    • Wang, Y.; Huang, W. C.; Wang, C. Y.; Tsai, C. C.; Chen, C. L.; Chang, Y. T.; Kai, J. I.; and Lin, C. F. (2009) Inhibiting glycogen synthase kinase-3 reduces endotoxaemic acute renal failure by down-regulating inflammation and renal cell apoptosis, Br. J. Pharmacol.; 157, 1004-1013.
    • (2009) Br. J. Pharmacol. , vol.157 , pp. 1004-1013
    • Wang, Y.1    Huang, W.C.2    Wang, C.Y.3    Tsai, C.C.4    Chen, C.L.5    Chang, Y.T.6    Kai, J.I.7    Lin, C.F.8
  • 57
    • 84879526538 scopus 로고    scopus 로고
    • Chronic lithium treatment protects against liver ischemia/reperfusion injury in rats
    • 23696274
    • Liu, A.; Fang, H.; Dahmen, U.; and Dirsch, O. (2013) Chronic lithium treatment protects against liver ischemia/reperfusion injury in rats, Liver Transpl.; 19, 762-772.
    • (2013) Liver Transpl. , vol.19 , pp. 762-772
    • Liu, A.1    Fang, H.2    Dahmen, U.3    Dirsch, O.4
  • 58
    • 8744271562 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 in insulin and wnt signaling: A double-edged sword?
    • 1:CAS:528:DC%2BD2cXptVSlsLo%3D 15494020
    • Patel, S.; Doble, B.; and Woodgett, J. R. (2004) Glycogen synthase kinase-3 in insulin and wnt signaling: a double-edged sword? Biochem. Soc. Trans.; 32, 803-808.
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 803-808
    • Patel, S.1    Doble, B.2    Woodgett, J.R.3
  • 59
    • 84875089976 scopus 로고    scopus 로고
    • Effects of lithium and valproic acid on gene expression and phenotypic markers in an NT2 neurosphere model of neural development
    • 1:CAS:528:DC%2BC3sXltFSktLo%3D 3602582 23527032
    • Hill, E. J.; Nagel, D. A.; O'Neil, J. D.; Torr, E.; Woehrling, E. K.; Devitt, A.; and Coleman, M. D. (2013) Effects of lithium and valproic acid on gene expression and phenotypic markers in an NT2 neurosphere model of neural development, PLoS One, 8, e58822.
    • (2013) PLoS One , vol.8 , pp. 58822
    • Hill, E.J.1    Nagel, D.A.2    O'Neil, J.D.3    Torr, E.4    Woehrling, E.K.5    Devitt, A.6    Coleman, M.D.7
  • 60
    • 84864823875 scopus 로고    scopus 로고
    • Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain
    • 1:CAS:528:DC%2BC38XhtlSktLbL 22800605
    • Huo, K.; Sun, Y.; Li, H.; Du, X.; Wang, X.; Karlsson, N.; Zhu, C.; and Blomgren, K. (2012) Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain, Mol. Cell Neurosci.; 51, 32-42.
    • (2012) Mol. Cell Neurosci. , vol.51 , pp. 32-42
    • Huo, K.1    Sun, Y.2    Li, H.3    Du, X.4    Wang, X.5    Karlsson, N.6    Zhu, C.7    Blomgren, K.8
  • 61
    • 80053570706 scopus 로고    scopus 로고
    • Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells
    • 1:CAS:528:DC%2BC3MXht1OrtrbE 3208156 21587270
    • Li, H.; Li, Q.; Du, X.; Sun, Y.; Wang, X.; Kroemer, G.; Blomgren, K.; and Zhu, C. (2011) Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells, J. Cereb. Blood Flow Metab.; 31, 2106-2115.
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , pp. 2106-2115
    • Li, H.1    Li, Q.2    Du, X.3    Sun, Y.4    Wang, X.5    Kroemer, G.6    Blomgren, K.7    Zhu, C.8
  • 62
    • 84856381277 scopus 로고    scopus 로고
    • Lithium in the treatment of neutropenia
    • 1:CAS:528:DC%2BC3MXhs1Shu7rK 22123660
    • Petrini, M.; and Azzara, A. (2012) Lithium in the treatment of neutropenia, Curr. Opin. Hematol.; 19, 52-57.
    • (2012) Curr. Opin. Hematol. , vol.19 , pp. 52-57
    • Petrini, M.1    Azzara, A.2
  • 63
    • 84859199697 scopus 로고    scopus 로고
    • The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation
    • 1:CAS:528:DC%2BC38Xlt1Oku7g%3D 22327222
    • Walasek, M. A.; Bystrykh, L.; van den Boom, V.; Olthof, S.; Ausema, A.; Ritsema, M.; Huls, G.; de Haan, G.; and van Os, R. (2012) The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation, Blood, 119, 3050-3059.
    • (2012) Blood , vol.119 , pp. 3050-3059
    • Walasek, M.A.1    Bystrykh, L.2    Van Den Boom, V.3    Olthof, S.4    Ausema, A.5    Ritsema, M.6    Huls, G.7    De Haan, G.8    Van Os, R.9
  • 64
    • 84888000534 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells treated by GSK-3 inhibitors
    • 1:CAS:528:DC%2BC3sXhtVOrsbjM 23839780
    • Eslaminejad, M. B.; Karimi, N.; and Shahhoseini, M. (2013) Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells treated by GSK-3 inhibitors, Histochem. Cell Biol.; 140, 623-633.
    • (2013) Histochem. Cell Biol. , vol.140 , pp. 623-633
    • Eslaminejad, M.B.1    Karimi, N.2    Shahhoseini, M.3
  • 66
    • 84873804317 scopus 로고    scopus 로고
    • High throughput transcriptome profiling of lithium stimulated human mesenchymal stem cells reveals priming towards osteoblastic lineage
    • 1:CAS:528:DC%2BC3sXis1aqsb4%3D 3559497 23383279
    • Satija, N. K.; Sharma, D.; Afrin, F.; Tripathi, R. P.; and Gangenahalli, G. (2013) High throughput transcriptome profiling of lithium stimulated human mesenchymal stem cells reveals priming towards osteoblastic lineage, PLoS One, 8, e55769.
    • (2013) PLoS One , vol.8 , pp. 55769
    • Satija, N.K.1    Sharma, D.2    Afrin, F.3    Tripathi, R.P.4    Gangenahalli, G.5
  • 67
    • 30044444251 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation
    • 1:CAS:528:DC%2BD28Xht1Kmsw%3D%3D 16341242
    • Trowbridge, J. J.; Xenocostas, A.; Moon, R. T.; and Bhatia, M. (2006) Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation, Nat. Med.; 12, 89-98.
    • (2006) Nat. Med. , vol.12 , pp. 89-98
    • Trowbridge, J.J.1    Xenocostas, A.2    Moon, R.T.3    Bhatia, M.4
  • 68
    • 84870866912 scopus 로고    scopus 로고
    • Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways
    • 1:CAS:528:DC%2BC38Xhs1CktL3J 3518679 23142822
    • Huang, J.; Nguyen-McCarty, M.; Hexner, E. O.; Danet-Desnoyers, G.; and Klein, P. S. (2012) Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways, Nat. Med.; 18, 1778-1785.
    • (2012) Nat. Med. , vol.18 , pp. 1778-1785
    • Huang, J.1    Nguyen-Mccarty, M.2    Hexner, E.O.3    Danet-Desnoyers, G.4    Klein, P.S.5
  • 69
    • 80053309997 scopus 로고    scopus 로고
    • Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model
    • 3183311 21836090
    • Tsai, L. K.; Wang, Z.; Munasinghe, J.; Leng, Y.; Leeds, P.; and Chuang, D. M. (2011) Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model, Stroke, 42, 2932-2939.
    • (2011) Stroke , vol.42 , pp. 2932-2939
    • Tsai, L.K.1    Wang, Z.2    Munasinghe, J.3    Leng, Y.4    Leeds, P.5    Chuang, D.M.6
  • 70
    • 84877582796 scopus 로고    scopus 로고
    • Inflammatory pre-conditioning of mesenchymal multipotent stromal cells improves their immunomodulatory potency in acute pyelonephritis in rats
    • 1:CAS:528:DC%2BC3sXht1ylur7P 23562307
    • Plotnikov, E. Y.; Pulkova, N. V.; Pevzner, I. B.; Zorova, L. D.; Silachev, D. N.; Morosanova, M. A.; Sukhikh, G. T.; and Zorov, D. B. (2013) Inflammatory pre-conditioning of mesenchymal multipotent stromal cells improves their immunomodulatory potency in acute pyelonephritis in rats, Cytotherapy, 15, 679-689.
    • (2013) Cytotherapy , vol.15 , pp. 679-689
    • Plotnikov, E.Y.1    Pulkova, N.V.2    Pevzner, I.B.3    Zorova, L.D.4    Silachev, D.N.5    Morosanova, M.A.6    Sukhikh, G.T.7    Zorov, D.B.8
  • 71
    • 84879413529 scopus 로고    scopus 로고
    • Resolution of inflammation: Mechanisms and opportunity for drug development
    • 1:CAS:528:DC%2BC3sXnsVyiu7Y%3D 23583354
    • Alessandri, A. L.; Sousa, L. P.; Lucas, C. D.; Rossi, A. G.; Pinho, V.; and Teixeira, M. M. (2013) Resolution of inflammation: mechanisms and opportunity for drug development, Pharmacol. Ther.; 139, 189-212.
    • (2013) Pharmacol. Ther. , vol.139 , pp. 189-212
    • Alessandri, A.L.1    Sousa, L.P.2    Lucas, C.D.3    Rossi, A.G.4    Pinho, V.5    Teixeira, M.M.6
  • 72
    • 73149097234 scopus 로고    scopus 로고
    • Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)
    • 1:CAS:528:DC%2BC3cXkt1ejtg%3D%3D 2818223 19836308
    • Beurel, E.; Michalek, S. M.; and Jope, R. S. (2010) Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3), Trends Immunol.; 31, 24-31.
    • (2010) Trends Immunol. , vol.31 , pp. 24-31
    • Beurel, E.1    Michalek, S.M.2    Jope, R.S.3
  • 73
    • 0035422071 scopus 로고    scopus 로고
    • The effects of lithium on ex vivo cytokine production
    • 1:CAS:528:DC%2BD3MXmtFSru70%3D 11513821
    • Rapaport, M. H.; and Manji, H. K. (2001) The effects of lithium on ex vivo cytokine production, Biol. Psychiatry, 50, 217-224.
    • (2001) Biol. Psychiatry , vol.50 , pp. 217-224
    • Rapaport, M.H.1    Manji, H.K.2
  • 74
    • 35748970179 scopus 로고    scopus 로고
    • An imbalance in the production of IL-1β and IL-6 by monocytes of bipolar patients: Restoration by lithium treatment
    • 1:CAS:528:DC%2BD1cXisVKr 17988365
    • Knijff, E. M.; Breunis, M. N.; Kupka, R. W.; de Wit, H. J.; Ruwhof, C.; Akkerhuis, G. W.; Nolen, W. A.; and Drexhage, H. A. (2007) An imbalance in the production of IL-1β and IL-6 by monocytes of bipolar patients: restoration by lithium treatment, Bipolar Disord.; 9, 743-753.
    • (2007) Bipolar Disord. , vol.9 , pp. 743-753
    • Knijff, E.M.1    Breunis, M.N.2    Kupka, R.W.3    De Wit, H.J.4    Ruwhof, C.5    Akkerhuis, G.W.6    Nolen, W.A.7    Drexhage, H.A.8
  • 76
    • 84863012874 scopus 로고    scopus 로고
    • Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury
    • 3261788 21895523
    • Yu, F.; Wang, Z.; Tchantchou, F.; Chiu, C. T.; Zhang, Y.; and Chuang, D. M. (2012) Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury, J. Neurotrauma, 29, 362-374.
    • (2012) J. Neurotrauma , vol.29 , pp. 362-374
    • Yu, F.1    Wang, Z.2    Tchantchou, F.3    Chiu, C.T.4    Zhang, Y.5    Chuang, D.M.6
  • 77
    • 78249233264 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β: A master regulator of toll-like receptor-mediated chronic intestinal inflammation
    • 20848477
    • Hofmann, C.; Dunger, N.; Scholmerich, J.; Falk, W.; and Obermeier, F. (2010) Glycogen synthase kinase 3β: a master regulator of toll-like receptor-mediated chronic intestinal inflammation, Inflamm. Bowel Dis.; 16, 1850-1858.
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 1850-1858
    • Hofmann, C.1    Dunger, N.2    Scholmerich, J.3    Falk, W.4    Obermeier, F.5
  • 78
    • 84875942000 scopus 로고    scopus 로고
    • Protective effects of lithium: A new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis
    • 1:CAS:528:DC%2BC3sXntlSmurY%3D 23542012
    • Albayrak, A.; Halici, Z.; Polat, B.; Karakus, E.; Cadirci, E.; Bayir, Y.; Kunak, S.; Karcioglu, S. S.; Yigit, S.; Unal, D.; and Atamanalp, S. S. (2013) Protective effects of lithium: a new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis, Int. Immunopharmacol.; 16, 35-40.
    • (2013) Int. Immunopharmacol. , vol.16 , pp. 35-40
    • Albayrak, A.1    Halici, Z.2    Polat, B.3    Karakus, E.4    Cadirci, E.5    Bayir, Y.6    Kunak, S.7    Karcioglu, S.S.8    Yigit, S.9    Unal, D.10    Atamanalp, S.S.11
  • 79
    • 79952153637 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3β activity with lithium in vitro attenuates sepsis-induced changes in muscle protein turnover
    • 1:CAS:528:DC%2BC3MXitVOjs7o%3D 3602924 20926980
    • Bertsch, S.; Lang, C. H.; and Vary, T. C. (2011) Inhibition of glycogen synthase kinase 3β activity with lithium in vitro attenuates sepsis-induced changes in muscle protein turnover, Shock, 35, 266-274.
    • (2011) Shock , vol.35 , pp. 266-274
    • Bertsch, S.1    Lang, C.H.2    Vary, T.C.3
  • 80
    • 84861792135 scopus 로고    scopus 로고
    • Effects of lithium on lipopolysaccharide-induced inflammation in rat primary glia cells
    • 1:CAS:528:DC%2BC38XotFWlsLo%3D 21994254
    • Nahman, S.; Belmaker, R. H.; and Azab, A. N. (2012) Effects of lithium on lipopolysaccharide-induced inflammation in rat primary glia cells, Innate Immun.; 18, 447-458.
    • (2012) Innate Immun. , vol.18 , pp. 447-458
    • Nahman, S.1    Belmaker, R.H.2    Azab, A.N.3
  • 81
    • 72749101711 scopus 로고    scopus 로고
    • Is lithium in a class of its own? A brief profile of its clinical use
    • Malhi, G. S.; Adams, D.; and Berk, M. (2009) Is lithium in a class of its own? A brief profile of its clinical use, Aust. NZ J. Psychiatry, 43, 1096-1104.
    • (2009) Aust. NZ J. Psychiatry , vol.43 , pp. 1096-1104
    • Malhi, G.S.1    Adams, D.2    Berk, M.3
  • 82
    • 84857643018 scopus 로고    scopus 로고
    • Lithium toxicity profile: A systematic review and meta-analysis
    • 1:CAS:528:DC%2BC38XivVels7Y%3D 22265699
    • McKnight, R. F.; Adida, M.; Budge, K.; Stockton, S.; Goodwin, G. M.; and Geddes, J. R. (2012) Lithium toxicity profile: a systematic review and meta-analysis, Lancet, 379, 721-728.
    • (2012) Lancet , vol.379 , pp. 721-728
    • McKnight, R.F.1    Adida, M.2    Budge, K.3    Stockton, S.4    Goodwin, G.M.5    Geddes, J.R.6
  • 83
    • 0141719652 scopus 로고    scopus 로고
    • Drug research: The ups and downs of lithium
    • 1:CAS:528:DC%2BD3sXntFCju7Y%3D 12968146
    • Pilcher, H. R. (2003) Drug research: the ups and downs of lithium, Nature, 425, 118-120.
    • (2003) Nature , vol.425 , pp. 118-120
    • Pilcher, H.R.1
  • 84
    • 77957352508 scopus 로고    scopus 로고
    • Effects of chronic lithium treatment on renal function
    • 1:CAS:528:DC%2BC3cXht1Wgsr3M 20483164
    • Tredget, J.; Kirov, A.; and Kirov, G. (2010) Effects of chronic lithium treatment on renal function, J. Affect. Disord.; 126, 436-440.
    • (2010) J. Affect. Disord. , vol.126 , pp. 436-440
    • Tredget, J.1    Kirov, A.2    Kirov, G.3
  • 85
    • 0037228105 scopus 로고    scopus 로고
    • Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey
    • 12500213
    • Coresh, J.; Astor, B. C.; Greene, T.; Eknoyan, G.; and Levey, A. S. (2003) Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey, Am. J. Kidney Dis.; 41, 1-12.
    • (2003) Am. J. Kidney Dis. , vol.41 , pp. 1-12
    • Coresh, J.1    Astor, B.C.2    Greene, T.3    Eknoyan, G.4    Levey, A.S.5
  • 86
    • 0021062911 scopus 로고
    • Decreasing lithium dosage reduces morbidity and side-effects during prophylaxis
    • 1:STN:280:DyaL2c7ht1arsA%3D%3D 6229567
    • Coppen, A.; Abou-Saleh, M.; Milln, P.; Bailey, J.; and Wood, K. (1983) Decreasing lithium dosage reduces morbidity and side-effects during prophylaxis, J. Affect. Disord.; 5, 353-362.
    • (1983) J. Affect. Disord. , vol.5 , pp. 353-362
    • Coppen, A.1    Abou-Saleh, M.2    Milln, P.3    Bailey, J.4    Wood, K.5
  • 87
    • 84868237290 scopus 로고    scopus 로고
    • Using lithium as a neuroprotective agent in patients with cancer
    • 1:CAS:528:DC%2BC3sXhtlCqtbo%3D 3520780 23121766
    • Khasraw, M.; Ashley, D.; Wheeler, G.; and Berk, M. (2012) Using lithium as a neuroprotective agent in patients with cancer, BMC Med.; 10, 131.
    • (2012) BMC Med. , vol.10 , pp. 131
    • Khasraw, M.1    Ashley, D.2    Wheeler, G.3    Berk, M.4
  • 88
    • 84878540178 scopus 로고    scopus 로고
    • Lithium: A versatile tool for understanding renal physiology
    • 1:CAS:528:DC%2BC3sXpt1yitrg%3D 3651632 23408166
    • Kishore, B. K.; and Ecelbarger, C. M. (2013) Lithium: a versatile tool for understanding renal physiology, Am. J. Physiol. Renal. Physiol.; 304, F1139-1149; doi: 10.1152/ajprenal.00718.2012; Epub 2013 Feb 13.
    • (2013) Am. J. Physiol. Renal. Physiol. , vol.304 , pp. 1139-1149
    • Kishore, B.K.1    Ecelbarger, C.M.2
  • 89
    • 84878218449 scopus 로고    scopus 로고
    • Therapeutic potential of mood stabilizers lithium and valproic acid: Beyond bipolar disorder
    • 1:CAS:528:DC%2BC3sXjt1SktbY%3D 3565922 23300133
    • Chiu, C. T.; Wang, Z.; Hunsberger, J. G.; and Chuang, D. M. (2013) Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder, Pharmacol. Rev.; 65, 105-142.
    • (2013) Pharmacol. Rev. , vol.65 , pp. 105-142
    • Chiu, C.T.1    Wang, Z.2    Hunsberger, J.G.3    Chuang, D.M.4


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