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Volumn 29, Issue 2, 2012, Pages 362-374

Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury

Author keywords

GSK 3b; lithium; neuroinflammation; neuroprotection; traumatic brain injury

Indexed keywords

CYCLOOXYGENASE 2; GELATINASE B; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; NEUROPROTECTIVE AGENT; SERINE;

EID: 84863012874     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.1942     Document Type: Article
Times cited : (107)

References (59)
  • 1
    • 40149097433 scopus 로고    scopus 로고
    • Selective Loss of Brain-Derived Neurotrophic Factor in the Dentate Gyrus Attenuates Antidepressant Efficacy
    • DOI 10.1016/j.biopsych.2007.09.019, PII S0006322307008943
    • Adachi, M., Barrot, M., Autry, A.E., Theobald, D., and Mon-teggia, L.M. (2008). Selective loss of brain-derived neuro-trophic factor in the dentate gyrus attenuates antidepressant efficacy. Biol. Psychiatry 63, 642-649. (Pubitemid 351329281)
    • (2008) Biological Psychiatry , vol.63 , Issue.7 , pp. 642-649
    • Adachi, M.1    Barrot, M.2    Autry, A.E.3    Theobald, D.4    Monteggia, L.M.5
  • 2
    • 59349102320 scopus 로고    scopus 로고
    • Ge-netic disruption of cyclooxygenase-2 does not improve histo-logical or behavioral outcome after traumatic brain injury in mice
    • Ahmad, M., Rose, M.E., Vagni, V., Griffith, R.P., Dixon, C.E., Kochanek, P.M., Hickey, R.W., and Graham, S.H. (2008). Ge-netic disruption of cyclooxygenase-2 does not improve histo-logical or behavioral outcome after traumatic brain injury in mice. J. Neurosci. Res. 86, 3605-3612.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 3605-3612
    • Ahmad, M.1    Rose, M.E.2    Vagni, V.3    Griffith, R.P.4    Dixon, C.E.5    Kochanek, P.M.6    Hickey, R.W.7    Graham, S.H.8
  • 3
    • 77949540912 scopus 로고    scopus 로고
    • Emerging roles of PGE2 receptors in models of neurological disease
    • Andreasson, K. (2010). Emerging roles of PGE2 receptors in models of neurological disease. Prostaglandins Other Lipid Mediat. 91, 104-112.
    • (2010) Prostaglandins Other Lipid Mediat. , vol.91 , pp. 104-112
    • Andreasson, K.1
  • 5
    • 73149097234 scopus 로고    scopus 로고
    • Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)
    • Beurel, E., Michalek, S.M., and Jope, R.S. (2010). Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). Trends Immunol. 31, 24-31.
    • (2010) Trends Immunol. , vol.31 , pp. 24-31
    • Beurel, E.1    Michalek, S.M.2    Jope, R.S.3
  • 6
    • 0033773645 scopus 로고    scopus 로고
    • Opposing actions of phos-phatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity
    • Bijur, G.N., and Jope, R.S. (2000). Opposing actions of phos-phatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity. J. Neurochem. 75, 2401-2408.
    • (2000) J. Neurochem. , vol.75 , pp. 2401-2408
    • Bijur, G.N.1    Jope, R.S.2
  • 7
    • 34347356395 scopus 로고    scopus 로고
    • Progressive damage after brain and spinal cord injury: pathomechanisms and treatment strategies
    • DOI 10.1016/S0079-6123(06)61009-1, PII S0079612306610091
    • Bramlett, H.M., and Dietrich, W.D. (2007). Progressive damage after brain and spinal cord injury: pathomechanisms and treatment strategies. Prog. Brain Res. 161, 125-141. (Pubitemid 47017402)
    • (2007) Progress in Brain Research , vol.161 , pp. 125-141
    • Bramlett, H.M.1    Dietrich, W.D.2
  • 8
    • 0036460393 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase 2 by nimesulide improves cognitive outcome more than motor outcome following diffuse traumatic brain injury in rats
    • DOI 10.1007/s00221-002-1245-z
    • Cernak, I., O'Connor, C., and Vink, R (2002). Inhibition of cy-clooxygenase 2 by nimesulide improves cognitive outcome more than motor outcome following diffuse traumatic brain injury in rats. Exp. Brain Res. 147, 193-199. (Pubitemid 35471799)
    • (2002) Experimental Brain Research , vol.147 , Issue.2 , pp. 193-199
    • Cernak, I.1    O'Connor, C.2    Vink, R.3
  • 11
    • 77957019846 scopus 로고    scopus 로고
    • Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders
    • Chiu, C.T., and Chuang, D.M. (2010). Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders. Pharmacol. Ther. 128, 281-304.
    • (2010) Pharmacol. Ther. , vol.128 , pp. 281-304
    • Chiu, C.T.1    Chuang, D.M.2
  • 12
    • 34250222104 scopus 로고    scopus 로고
    • In Search of the Holy Grail for the Treatment of Neurodegenerative Disorders: Has a Simple Cation Been Overlooked?
    • DOI 10.1016/j.biopsych.2007.04.008, PII S0006322307003484
    • Chuang, D.M., and Manji, H.K. (2007). In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked? Biol. Psychiatry 62, 4-6. (Pubitemid 46898231)
    • (2007) Biological Psychiatry , vol.62 , Issue.1 , pp. 4-6
    • Chuang, D.-M.1    Manji, H.K.2
  • 13
    • 68249103676 scopus 로고    scopus 로고
    • Neutralization of interleukin-1beta modifies the inflammatory response and improves his-tological and cognitive outcome following traumatic brain injury in mice
    • Clausen, F., Hanell, A., Bjork, M., Hillered, L., Mir, A.K., Gram, H., and Marklund, N. (2009). Neutralization of interleukin-1beta modifies the inflammatory response and improves his-tological and cognitive outcome following traumatic brain injury in mice. Eur. J. Neurosci. 30, 385-396.
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 385-396
    • Clausen, F.1    Hanell, A.2    Bjork, M.3    Hillered, L.4    Mir, A.K.5    Gram, H.6    Marklund, N.7
  • 14
    • 77956197481 scopus 로고    scopus 로고
    • Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats
    • Dash, P.K., Orsi, S.A., Zhang, M., Grill, R.J., Pati, S., Zhao, J., and Moore, A.N (2010). Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats. PLoS One 5, e11383.
    • (2010) PLoS One , vol.5
    • Dash, P.K.1    Orsi, S.A.2    Zhang, M.3    Grill, R.J.4    Pati, S.5    Zhao, J.6    Moore, A.N.7
  • 16
    • 0031693773 scopus 로고    scopus 로고
    • Sustained sensory/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouse
    • Fox, G.B., Fan, L., Levasseur, R.A., and Faden, A.I. (1998). Sus-tained sensory/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouse. J. Neurotrauma 15, 599-614. (Pubitemid 28413053)
    • (1998) Journal of Neurotrauma , vol.15 , Issue.8 , pp. 599-614
    • Fox, G.B.1    Fan, L.2    Levasseur, R.A.3    Faden, A.I.4
  • 17
    • 4043167143 scopus 로고    scopus 로고
    • Motor and cognitive function evaluation following experimental traumatic brain injury
    • DOI 10.1016/j.neubiorev.2004.06.002, PII S0149763404000673
    • Fujimoto, S.T., Longhi, L., Saatman, K.E., Conte, V., Stocchetti, N., and McIntosh, T.K. (2004). Motor and cognitive function evaluation following experimental traumatic brain injury. Neurosci. Biobehav. Rev. 28, 365-378. (Pubitemid 39077928)
    • (2004) Neuroscience and Biobehavioral Reviews , vol.28 , Issue.4 , pp. 365-378
    • Fujimoto, S.T.1    Longhi, L.2    Saatman, K.E.3    McIntosh, T.K.4
  • 18
    • 48249135748 scopus 로고    scopus 로고
    • Selective death of newborn neurons in hip-pocampal dentate gyrus following moderate experimental traumatic brain injury
    • Gao, X., Deng-Bryant, Y., Cho, W., Carrico, K.M., Hall, E.D., and Chen, J. (2008). Selective death of newborn neurons in hip-pocampal dentate gyrus following moderate experimental traumatic brain injury. J. Neurosci. Res. 86, 2258-2270.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 2258-2270
    • Gao, X.1    Deng-Bryant, Y.2    Cho, W.3    Carrico, K.M.4    Hall, E.D.5    Chen, J.6
  • 19
    • 40949158910 scopus 로고    scopus 로고
    • Evolution of post-traumatic neurodegeneration after controlled cortical impact traumatic brain injury in mice and rats as assessed by the de Olmos silver and fluorojade staining methods
    • DOI 10.1089/neu.2007.0383
    • Hall, E.D., Bryant, Y.D., Cho, W., and Sullivan, P.G. (2008). Evolution of post-traumatic neurodegeneration after con-trolled cortical impact traumatic brain injury in mice and rats as assessed by the de Olmos silver and fluorojade staining methods. J. Neurotrauma 25, 235-247. (Pubitemid 351416738)
    • (2008) Journal of Neurotrauma , vol.25 , Issue.3 , pp. 235-247
    • Hall, E.D.1    Bryant, Y.D.2    Cho, W.3    Sullivan, P.G.4
  • 20
    • 72949115293 scopus 로고    scopus 로고
    • Anti- oxidant therapies for traumatic brain injury
    • Hall, E.D., Vaishnav, R.A., and Mustafa, A.G. (2010). Anti- oxidant therapies for traumatic brain injury. Neurother- apeutics 7, 51-61.
    • (2010) Neurother- Apeutics , vol.7 , pp. 51-61
    • Hall, E.D.1    Vaishnav, R.A.2    Mustafa, A.G.3
  • 21
    • 0032947795 scopus 로고    scopus 로고
    • Anti-bipolar therapy: Mechanism of action of lithium
    • Jope, R.S. (1999). Anti-bipolar therapy: mechanism of action of lithium. Mol. Psychiatry 4, 117-128. (Pubitemid 29163975)
    • (1999) Molecular Psychiatry , vol.4 , Issue.2 , pp. 117-128
    • Jope, R.S.1
  • 22
    • 0042379932 scopus 로고    scopus 로고
    • Lithium and GSK-3: One inhibitor, two inhibitory actions, multiple outcomes
    • DOI 10.1016/S0165-6147(03)00206-2
    • Jope, R.S. (2003). Lithium and GSK-3: one inhibitor, two inhibi- tory actions, multiple outcomes. Trends Pharmacol. Sci. 24, 441-443. (Pubitemid 37088166)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.9 , pp. 441-443
    • Jope, R.S.1
  • 23
    • 70349757546 scopus 로고    scopus 로고
    • Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice
    • Kelso, M.L., Scheff, S.W., Pauly, J.R., and Loftin, C.D. (2009). Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice. BMC Neurosci. 10, 108.
    • (2009) BMC Neurosci. , vol.10 , pp. 108
    • Kelso, M.L.1    Scheff, S.W.2    Pauly, J.R.3    Loftin, C.D.4
  • 24
    • 34248530339 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: Multiple mechanisms of action
    • DOI 10.1124/jpet.107.120188
    • Kim, H.J., Rowe, M., Ren, M., Hong, J.S., Chen, P.S., and Chuang, D.M. (2007). Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat per- manent ischemic model of stroke: multiple mechanisms of action. J. Pharmacol. Exp. Ther. 321, 892-901. (Pubitemid 46762687)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.321 , Issue.3 , pp. 892-901
    • Hyeon, J.K.1    Rowe, M.2    Ren, M.3    Hong, J.-S.4    Chen, P.-S.5    Chuang, D.-M.6
  • 25
    • 17044423920 scopus 로고    scopus 로고
    • Lithium-mediated phosphorylation of glycogen synthase kinase-3β involves PI3 kinase-dependent activation of protein kinase C-α
    • DOI 10.1385/JMN:24:2:237
    • Kirshenboim, N., Plotkin, B., Shlomo, S.B., Kaidanovich-Beilin, O., and Eldar-Finkelman, H. (2004). Lithium-mediated phos- phorylation of glycogen synthase kinase-3beta involves PI3 kinase-dependent activation of protein kinase C-alpha. J. Mol. Neurosci. 24, 237-245. (Pubitemid 41359151)
    • (2004) Journal of Molecular Neuroscience , vol.24 , Issue.2 , pp. 237-245
    • Kirshenboim, N.1    Plotkin, B.2    Shlomo, S.B.3    Kaidanovich-Beilin, O.4    Eldar-Finkelman, H.5
  • 27
    • 44149110850 scopus 로고    scopus 로고
    • Inhibition of GSK-3 reduces infarct volume and im- proves neurobehavioral functions
    • Koh, S.H., Yoo, A.R., Chang, D.I., Hwang, S.J., and Kim, S.H. (2008). Inhibition of GSK-3 reduces infarct volume and im- proves neurobehavioral functions. Biochem. Biophys. Res. Commun. 371, 894-899.
    • (2008) Biochem. Biophys. Res. Commun. , vol.371 , pp. 894-899
    • Koh, S.H.1    Yoo, A.R.2    Chang, D.I.3    Hwang, S.J.4    Kim, S.H.5
  • 28
    • 0036737399 scopus 로고    scopus 로고
    • Cyclooxygenase-2, prostaglandin synthases, and prostaglan- din H2 metabolism in traumatic brain injury in the rat
    • Kunz, T., Marklund, N., Hillered, L., and Oliw, E.H. (2002). Cyclooxygenase-2, prostaglandin synthases, and prostaglan- din H2 metabolism in traumatic brain injury in the rat. J. Neurotrauma 19, 1051-1064.
    • (2002) J. Neurotrauma , vol.19 , pp. 1051-1064
    • Kunz, T.1    Marklund, N.2    Hillered, L.3    Oliw, E.H.4
  • 29
    • 33644608758 scopus 로고    scopus 로고
    • Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat
    • Kunz, T., Marklund, N., Hillered, L., and Oliw, E.H. (2006). Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat. Restor. Neurol. Neurosci. 24, 55-63.
    • (2006) Restor. Neurol. Neurosci. , vol.24 , pp. 55-63
    • Kunz, T.1    Marklund, N.2    Hillered, L.3    Oliw, E.H.4
  • 30
    • 33750054677 scopus 로고    scopus 로고
    • Differential roles of glycogen synthase kinase-3 isoforms in the regulation of transcriptional activation
    • Liang, M.H., and Chuang, D.M. (2006). Differential roles of glycogen synthase kinase-3 isoforms in the regulation of transcriptional activation. J. Biol. Chem. 281, 30479-30484.
    • (2006) J. Biol. Chem. , vol.281 , pp. 30479-30484
    • Liang, M.H.1    Chuang, D.M.2
  • 31
    • 33947519417 scopus 로고    scopus 로고
    • Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival
    • Liang, M.H., and Chuang, D.M. (2007). Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival. J. Biol. Chem. 282, 3904-3917.
    • (2007) J. Biol. Chem. , vol.282 , pp. 3904-3917
    • Liang, M.H.1    Chuang, D.M.2
  • 32
    • 78449310195 scopus 로고    scopus 로고
    • Neuroprotection for traumatic brain injury: Translational challenges and emerg- ing therapeutic strategies
    • Loane, D.J., and Faden, A.I. (2010). Neuroprotection for traumatic brain injury: translational challenges and emerg- ing therapeutic strategies. Trends Pharmacol. Sci. 31, 596- 604.
    • (2010) Trends Pharmacol. Sci. , vol.31 , pp. 596-604
    • Loane, D.J.1    Faden, A.I.2
  • 34
    • 69249093374 scopus 로고    scopus 로고
    • Alterations in blood-brain barrier permeability to large and small molecules and leukocyte accumulation after traumatic brain injury: Effects of post-traumatic hypothermia
    • Lotocki, G., Vaccari, J.P., Perez, E.R., Sanchez-Molano, J., Fur- ones-Alonso, O., Bramlett, H.M., and Dietrich, W.D. (2009). Alterations in blood-brain barrier permeability to large and small molecules and leukocyte accumulation after traumatic brain injury: effects of post-traumatic hypothermia. J. Neurotrauma 26, 1123-1134.
    • (2009) J. Neurotrauma , vol.26 , pp. 1123-1134
    • Lotocki, G.1    Vaccari, J.P.2    Perez, E.R.3    Sanchez-Molano, J.4    Furones-Alonso, O.5    Bramlett, H.M.6    Dietrich, W.D.7
  • 35
    • 78651312903 scopus 로고    scopus 로고
    • Is glycogen synthase kinase-3 a central modulator in mood regulation?
    • Li, X., and Jope, R.S. (2010). Is glycogen synthase kinase-3 a central modulator in mood regulation? Neuropsycho- pharmacology 35, 2143-2154.
    • (2010) Neuropsycho- Pharmacology , vol.35 , pp. 2143-2154
    • Li, X.1    Jope, R.S.2
  • 36
    • 46849094295 scopus 로고    scopus 로고
    • Moderate and severe traumatic brain injury in adults
    • DOI 10.1016/S1474-4422(08)70164-9, PII S1474442208701649
    • Maas, A.I., Stocchetti, N., and Bullock, R (2008). Moderate and severe traumatic brain injury in adults. Lancet Neurol. 7, 728-741. (Pubitemid 351957931)
    • (2008) The Lancet Neurology , vol.7 , Issue.8 , pp. 728-741
    • Maas, A.I.1    Stocchetti, N.2    Bullock, R.3
  • 37
    • 67849135779 scopus 로고    scopus 로고
    • Combination therapies for traumatic brain injury: Prospective considerations
    • Margulies, S., and Hicks, R. (2009). Combination therapies for traumatic brain injury: prospective considerations. J. Neuro-trauma 26, 925-939.
    • (2009) J. Neuro-trauma , vol.26 , pp. 925-939
    • Margulies, S.1    Hicks, R.2
  • 38
    • 0034651103 scopus 로고    scopus 로고
    • Cyclooxygenase-2 contributes to functional hyperemia in whisker-barrel cortex
    • Niwa, K., Araki, E., Morham, SG., Ross, M.E., and Iadecola, C. (2000). Cyclooxygenase-2 contributes to functional hyperemia in whisker-barrel cortex. J. Neurosci. 20, 763-770. (Pubitemid 30225578)
    • (2000) Journal of Neuroscience , vol.20 , Issue.2 , pp. 763-770
    • Niwa, K.1    Araki, E.2    Morham, S.G.3    Ross, M.E.4    Iadecola, C.5
  • 39
    • 0032557889 scopus 로고    scopus 로고
    • Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
    • Nonaka, S., and Chuang, D.M. (1998). Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats. Neuroreport 9, 2081-2084. (Pubitemid 28300570)
    • (1998) NeuroReport , vol.9 , Issue.9 , pp. 2081-2084
    • Nonaka, S.1    Chuang, D.-M.2
  • 40
    • 79956041531 scopus 로고    scopus 로고
    • Lentivirally mediated GSK-3beta silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice
    • Omata, N., Chiu, C.T., Moya, P.R., Leng, Y., Wang, Z., Huns-berger, J.G., Leeds, P., and Chuang, D.M. (2011). Lentivirally mediated GSK-3beta silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice. Int. J. Neuropsychopharmacol. 14, 711-717.
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 711-717
    • Omata, N.1    Chiu, C.T.2    Moya, P.R.3    Leng, Y.4    Wang, Z.5    Huns-Berger, J.G.6    Leeds, P.7    Chuang, D.M.8
  • 41
    • 70349771773 scopus 로고    scopus 로고
    • Depression-like and anxiety-like behavioural aftermaths of impact accelerated traumatic brain injury in rats: A model of comorbid depression and anxiety? Behav
    • Pandey, D.K., Yadav, S.K., Mahesh, R., and Rajkumar, R. (2009). Depression-like and anxiety-like behavioural aftermaths of impact accelerated traumatic brain injury in rats: a model of comorbid depression and anxiety? Behav. Brain Res. 205,436-442.
    • (2009) Brain Res. , vol.205 , pp. 436-442
    • Pandey, D.K.1    Yadav, S.K.2    Mahesh, R.3    Rajkumar, R.4
  • 42
    • 0037470154 scopus 로고    scopus 로고
    • The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: A review
    • DOI 10.1016/S0014-2999(03)01272-X
    • Prut, L., and Belzung, C. (2003). The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a re-view. Eur. J. Pharmacol. 463, 3-33. (Pubitemid 36205070)
    • (2003) European Journal of Pharmacology , vol.463 , Issue.1-3 , pp. 3-33
    • Prut, L.1    Belzung, C.2
  • 43
    • 77951943796 scopus 로고    scopus 로고
    • Novel insights into lithium's mechanism of ac-tion: Neurotrophic and neuroprotective effects
    • Quiroz, J.A., Machado-Vieira, R., Zarate, C.A., Jr., and Manji, H.K. (2010). Novel insights into lithium's mechanism of ac-tion: neurotrophic and neuroprotective effects. Neuropsycho-biology 62, 50-60.
    • Neuropsycho-biology , vol.62 , pp. 50-60
    • Quiroz, J.A.1    MacHado-Vieira, R.2    Zarate Jr., C.A.3
  • 45
    • 41149090849 scopus 로고    scopus 로고
    • MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke
    • DOI 10.1161/STROKEAHA.107.500868, PII 0000767020080400000013
    • Rosell, A., Cuadrado, E., Ortega-Aznar, A., Hernandez-Guilla-mon, M., Lo, E.H., and Montaner, J. (2008). MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke. Stroke 39, 1121-1126. (Pubitemid 351440679)
    • (2008) Stroke , vol.39 , Issue.4 , pp. 1121-1126
    • Rosell, A.1    Cuadrado, E.2    Ortega-Aznar, A.3    Hernandez-Guillamon, M.4    Lo, E.H.5    Montaner, J.6
  • 46
    • 34548012115 scopus 로고    scopus 로고
    • GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder
    • DOI 10.1016/j.neubiorev.2007.03.002, PII S0149763407000243
    • Rowe, M.K., Wiest, C., and Chuang, D.M. (2007). GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder. Neurosci. Biobehav. Rev. 31, 920-931. (Pubitemid 47285347)
    • (2007) Neuroscience and Biobehavioral Reviews , vol.31 , Issue.6 , pp. 920-931
    • Rowe, M.K.1    Wiest, C.2    Chuang, D.-M.3
  • 48
    • 2042512984 scopus 로고    scopus 로고
    • Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease
    • DOI 10.1038/sj.mp.4001463
    • Senatorov, V.V., Ren, M., Kanai, H., Wei, H., and Chuang, D.M. (2004). Short-term lithium treatment promotes neuronal sur-vival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease. Mol. Psychiatry 9, 371-385. (Pubitemid 38534698)
    • (2004) Molecular Psychiatry , vol.9 , Issue.4 , pp. 371-385
    • Senatorov, V.V.1    Ren, M.2    Kanai, H.3    Wei, H.4    Chuang, D.-M.5
  • 49
    • 33947603193 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3β in early depressive behavior induced by mild traumatic brain injury
    • DOI 10.1016/j.mcn.2006.12.006, PII S1044743106002910
    • Shapira, M., Licht, A., Milman, A., Pick, C.G., Shohami, E., and Eldar-Finkelman, H. (2007). Role of glycogen synthase kinase-3beta in early depressive behavior induced by mild traumatic brain injury. Mol. Cell. Neurosci. 34, 571-577. (Pubitemid 46483079)
    • (2007) Molecular and Cellular Neuroscience , vol.34 , Issue.4 , pp. 571-577
    • Shapira, M.1    Licht, A.2    Milman, A.3    Pick, C.G.4    Shohami, E.5    Eldar-Finkelman, H.6
  • 51
    • 77954862661 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury
    • Shlosberg, D., Benifla, M., Kaufer, D., and Friedman, A. (2010). Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury. Nat. Rev. Neurol. 6, 393-403.
    • (2010) Nat. Rev. Neurol. , vol.6 , pp. 393-403
    • Shlosberg, D.1    Benifla, M.2    Kaufer, D.3    Friedman, A.4
  • 53
    • 77955985165 scopus 로고    scopus 로고
    • Activated protein C analog with re-duced anticoagulant activity improves functional recovery and reduces bleeding risk following controlled cortical impact
    • Walker, C.T., Marky, A.H., Petraglia, A.L., Ali, T., Chow, N., and Zlokovic, B.V. (2010). Activated protein C analog with re-duced anticoagulant activity improves functional recovery and reduces bleeding risk following controlled cortical impact. Brain Res 1347, 125-131.
    • (2010) Brain Res , vol.1347 , pp. 125-131
    • Walker, C.T.1    Marky, A.H.2    Petraglia, A.L.3    Ali, T.4    Chow, N.5    Zlokovic, B.V.6
  • 54
    • 78650919356 scopus 로고    scopus 로고
    • Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: The roles of HDAC and MMP-9 inhibition
    • Wang, Z., Leng, Y., Tsai, L.K., Leeds, P., and Chuang, D.M. (2011). Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition. J. Cereb. Blood Flow Metab. 31, 52-57.
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , pp. 52-57
    • Wang, Z.1    Leng, Y.2    Tsai, L.K.3    Leeds, P.4    Chuang, D.M.5
  • 55
    • 58049196879 scopus 로고    scopus 로고
    • The mood stabilizers lithium and valproate se-lectively activate the promoter IV of brain-derived neuro-trophic factor in neurons
    • Yasuda, S., Liang, M.H., Marinova, Z., Yahyavi, A., and Chuang, D.M. (2009). The mood stabilizers lithium and valproate se-lectively activate the promoter IV of brain-derived neuro-trophic factor in neurons. Mol. Psychiatry 14, 51-59.
    • (2009) Mol. Psychiatry , vol.14 , pp. 51-59
    • Yasuda, S.1    Liang, M.H.2    Marinova, Z.3    Yahyavi, A.4    Chuang, D.M.5
  • 56
    • 40949153084 scopus 로고    scopus 로고
    • Induction of MMP-9 expression and endothelial injury by oxidative stress after spinal cord injury
    • DOI 10.1089/neu.2007.0438
    • Yu, F., Kamada, H., Niizuma, K., Endo, H., and Chan, P.H. (2008). Induction of mmp-9 expression and endothelial injury by oxidative stress after spinal cord injury. J. Neurotrauma 25, 184-195. (Pubitemid 351416743)
    • (2008) Journal of Neurotrauma , vol.25 , Issue.3 , pp. 184-195
    • Yu, F.1    Kamada, H.2    Niizuma, K.3    Endo, H.4    Chan, P.H.5
  • 57
    • 77955888790 scopus 로고    scopus 로고
    • Glial cell-mediated dete-rioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography
    • Yu, I., Inaji, M., Maeda, J., Okauchi, T., Nariai, T., Ohno, K., Higuchi, M., and Suhara, T. (2010). Glial cell-mediated dete-rioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography. J. Neurotrauma 27, 1463-1475.
    • (2010) J. Neurotrauma , vol.27 , pp. 1463-1475
    • Yu, I.1    Inaji, M.2    Maeda, J.3    Okauchi, T.4    Nariai, T.5    Ohno, K.6    Higuchi, M.7    Suhara, T.8
  • 58
    • 57749173844 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflamma-tion-induced neurotoxicity
    • Yuskaitis, C.J., and Jope, R.S. (2009). Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflamma-tion-induced neurotoxicity. Cell Signal. 21, 264-273.
    • (2009) Cell Signal. , vol.21 , pp. 264-273
    • Yuskaitis, C.J.1    Jope, R.S.2
  • 59
    • 77957666191 scopus 로고    scopus 로고
    • Neu-roprotective effect and cognitive outcome of chronic lithium on traumatic brain injury in mice
    • Zhu, Z.F., Wang, Q.G., Han, B.J., and William, C.P. (2010). Neu-roprotective effect and cognitive outcome of chronic lithium on traumatic brain injury in mice. Brain Res. Bull. 83, 272-277
    • (2010) Brain Res. Bull. , vol.83 , pp. 272-277
    • Zhu, Z.F.1    Wang, Q.G.2    Han, B.J.3    William, C.P.4


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