Inhibiting glycogen synthase kinase-3 reduces endotoxaemic acute renal failure by down-regulating inflammation and renal cell apoptosis

British Journal of Pharmacology

Volumn 157, Issue 6, 2009, Pages 1004-1013

  Wang, Y ^a   Huang, W C ^a   Wang, C Y ^a   Tsai, C C ^a   Chen, C L ^a   Chang, Y T ^a   Kai, J I ^a   Lin, C F ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Acute renal failure; Apoptosis; GSK 3; Inflammation; Lipopolysaccharide; TNF

Indexed keywords

CREATININE; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; LITHIUM CHLORIDE; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENDOTOXEMIA; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL; KIDNEY DYSFUNCTION; KIDNEY EPITHELIUM; KIDNEY FUNCTION; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NEPHRITIS; NEPHROTOXICITY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELLS, CULTURED; DOWN-REGULATION; ENDOTOXINS; GLYCOGEN SYNTHASE KINASE 3; INFLAMMATION MEDIATORS; KIDNEY FAILURE, ACUTE; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C3H; PROTEIN KINASE INHIBITORS; RATS; THIADIAZOLES;

EID: 70350337981     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00284.x     Document Type: Article

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