Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats

Toxicology and Applied Pharmacology

Volumn 280, Issue 1, 2014, Pages 1-9

  Chen, Haw Wen ^a   Huang, Chin Shiu ^b   Li, Chien Chun ^c,d   Lin, Ai Hsuan ^a   Huang, Yu Ju ^a   Wang, Tsu Shing ^c   Yao, Hsien Tsung ^a   Lii, Chong Kuei ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Andrographolide; Antioxidant enzymes; Bioavailability; Carbon tetrachloride; Hepatoprotection; Nrf2

Indexed keywords

ANDROGRAPHOLIDE; CARBON TETRACHLORIDE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; MESSENGER RNA; TRANSFERASE; AMINOTRANSFERASE; GLUTATHIONE TRANSFERASE; LIVER PROTECTIVE AGENT; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; DITERPENE;

AMINOTRANSFERASE BLOOD LEVEL; ANDROGRAPHIS PANICULATA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CARBON TETRACHLORIDE INDUCED OXIDATIVE DAMAGE; CONTROLLED STUDY; DNA BINDING; DRUG BIOAVAILABILITY; DRUG DETERMINATION; DRUG EFFECT; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID PEROXIDATION; LIVER PROTECTION; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING; ANIMAL TISSUE; AREA UNDER THE CURVE; BODY WEIGHT; CONSENSUS SEQUENCE; DRUG CLEARANCE; DRUG HALF LIFE; ENZYME BLOOD LEVEL; ERYTHROCYTE; GEL MOBILITY SHIFT ASSAY; IMMUNOBLOTTING; LIPID LIVER LEVEL; LIVER TOXICITY; MEAN RESIDENCE TIME; ORGAN WEIGHT; PROTEIN EXPRESSION; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BIOAVAILABILITY; BLOOD; DRUG EFFECTS; MALE; PHYSIOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL AVAILABILITY; CARBON TETRACHLORIDE; DITERPENES; MALE; OXIDATIVE STRESS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84906255505     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.07.024     Document Type: Article

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