Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation

Molecular Nutrition and Food Research

Volumn 57, Issue 11, 2013, Pages 1918-1930

  Huang, Chin Shiu ^a   Lin, Ai Hsuan ^b   Liu, Cheng Tzu ^b   Tsai, Chia Wen ^c   Chang, Ing Shr ^c   Chen, Haw Wen ^c   Lii, Chong Kuei ^c  

^a ASIA UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Adhesion molecules; Glutamate cysteine ligase; Heme oxygenase 1; Isothiocyanates; Nuclear factor erythroid 2 related factor 2 (Nrf2); Nuclear factor kappaB (NF B); Oxidized LDL

Indexed keywords

ANTIOXIDANT; BENZYL ISOTHIOCYANATE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; HMOX1 PROTEIN, HUMAN; ICAM1 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; ISOTHIOCYANIC ACID DERIVATIVE; LOW DENSITY LIPOPROTEIN; NFE2L2 PROTEIN, HUMAN; OXIDIZED LOW DENSITY LIPOPROTEIN; REACTIVE OXYGEN METABOLITE; SELE PROTEIN, HUMAN; SULFORAFAN; TRANSCRIPTION FACTOR NRF2; VASCULAR CELL ADHESION MOLECULE 1;

ADHESION MOLECULES; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL ADHESION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; LEUKOCYTE; METABOLISM; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 (NRF2); NUCLEAR FACTOR-KAPPAB (NFΚB); UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION;

ADHESION MOLECULES; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; ISOTHIOCYANATES; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 (NRF2); NUCLEAR FACTOR-KAPPAB (NFΚB); OXIDIZED LDL;

ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; CELL ADHESION; DOSE-RESPONSE RELATIONSHIP, DRUG; E-SELECTIN; GLUTAMATE-CYSTEINE LIGASE; HEME OXYGENASE-1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; ISOTHIOCYANATES; LEUKOCYTES; LIPOPROTEINS, LDL; NF-E2-RELATED FACTOR 2; NF-KAPPA B; REACTIVE OXYGEN SPECIES; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84886792157     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201300063     Document Type: Article

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