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Volumn 31, Issue 2, 2003, Pages 251-261

A simultaneous liquid chromatography/mass spectrometric assay of glutathione, cysteine, homocysteine and their disulfides in biological samples

Author keywords

Cysteine; Disulfides; Glutathione; Homocysteine; LC MS

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); CYSTEINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HOMOCYSTEINE; HOMOCYSTINE; THIOL;

EID: 0037467156     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(02)00594-0     Document Type: Article
Times cited : (269)

References (44)
  • 2
    • 0023630299 scopus 로고
    • Improved procedure for determining glutathione in plasma as an index of myocardial oxidative stress
    • Curello S., Ceconi C., Cargnoni A., Cornacchiari A., Ferrari R., Albertini A. Improved procedure for determining glutathione in plasma as an index of myocardial oxidative stress. Clin. Chem. 33:1987;1448-1449.
    • (1987) Clin. Chem. , vol.33 , pp. 1448-1449
    • Curello, S.1    Ceconi, C.2    Cargnoni, A.3    Cornacchiari, A.4    Ferrari, R.5    Albertini, A.6
  • 4
    • 0014481378 scopus 로고
    • Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27:1969;502-522.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 5
    • 0019167355 scopus 로고
    • Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
    • Griffith O.W. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106:1980;207-212.
    • (1980) Anal. Biochem. , vol.106 , pp. 207-212
    • Griffith, O.W.1
  • 6
    • 0022438240 scopus 로고
    • Improved method for determination of cellular thiols, disulfides and protein mixed disulfides using HPLC with electrochemical detection
    • Jensen C.B., Grossman S.J., Jollow D.J. Improved method for determination of cellular thiols, disulfides and protein mixed disulfides using HPLC with electrochemical detection. Adv. Exp. Med. Biol. 197:1986;407-413.
    • (1986) Adv. Exp. Med. Biol. , vol.197 , pp. 407-413
    • Jensen, C.B.1    Grossman, S.J.2    Jollow, D.J.3
  • 7
    • 0022447333 scopus 로고
    • High-performance liquid chromatographic analysis of glutathione and its thiol and disulfide degradation products
    • Stein A.F., Dills R.L., Klaassen C.D. High-performance liquid chromatographic analysis of glutathione and its thiol and disulfide degradation products. J. Chromatogr. 381:1986;259-270.
    • (1986) J. Chromatogr. , vol.381 , pp. 259-270
    • Stein, A.F.1    Dills, R.L.2    Klaassen, C.D.3
  • 8
    • 0028885739 scopus 로고
    • Simultaneous quantitation of oxidized and reduced glutathione in equine biological fluids by reversed-phase high-performance liquid chromatography using electrochemical detection
    • Smith N.C., Dunnett M., Mills P.C. Simultaneous quantitation of oxidized and reduced glutathione in equine biological fluids by reversed-phase high-performance liquid chromatography using electrochemical detection. J. Chromatogr. B. 673:1995;35-41.
    • (1995) J. Chromatogr. B , vol.673 , pp. 35-41
    • Smith, N.C.1    Dunnett, M.2    Mills, P.C.3
  • 9
    • 0027367640 scopus 로고
    • A high-performance liquid chromatographic assay for reduced and oxidized glutathione in biological samples
    • Jayatilleke E., Shaw S. A high-performance liquid chromatographic assay for reduced and oxidized glutathione in biological samples. Anal. Biochem. 214:1993;452-457.
    • (1993) Anal. Biochem. , vol.214 , pp. 452-457
    • Jayatilleke, E.1    Shaw, S.2
  • 10
    • 0031553958 scopus 로고    scopus 로고
    • Validated high-performance liquid chromatography-electrochemical method for determination of glutathione and glutathione disulfide in small tissue samples
    • Lakritz J., Plopper C.G., Buckpitt A.R. Validated high-performance liquid chromatography-electrochemical method for determination of glutathione and glutathione disulfide in small tissue samples. Anal. Biochem. 247:1997;63-68.
    • (1997) Anal. Biochem. , vol.247 , pp. 63-68
    • Lakritz, J.1    Plopper, C.G.2    Buckpitt, A.R.3
  • 11
    • 0019131878 scopus 로고
    • High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide and related thiols and disulfides
    • Reed D.J., Babson J.R., Beatty P.W., Brodie A.E., Ellis W.W., Potter D.W. High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide and related thiols and disulfides. Anal. Biochem. 106:1980;55-62.
    • (1980) Anal. Biochem. , vol.106 , pp. 55-62
    • Reed, D.J.1    Babson, J.R.2    Beatty, P.W.3    Brodie, A.E.4    Ellis, W.W.5    Potter, D.W.6
  • 12
    • 0018934470 scopus 로고
    • Estimation of glutathione in rat liver by reversed-phase high-performance liquid chromatography: Separation from cysteine and gamma-glutamylcysteine
    • Reeve J., Kuhlenkamp J., Kaplowitz N.E. Estimation of glutathione in rat liver by reversed-phase high-performance liquid chromatography: separation from cysteine and gamma-glutamylcysteine. J. Chromatogr. 194:1980;424-428.
    • (1980) J. Chromatogr. , vol.194 , pp. 424-428
    • Reeve, J.1    Kuhlenkamp, J.2    Kaplowitz, N.E.3
  • 13
    • 0025728695 scopus 로고
    • Measurement of reduced and oxidized glutathione in cultures of adult rat hepatocytes
    • Mertens K., Rogiers V., Sonck W., Vercruysse A. Measurement of reduced and oxidized glutathione in cultures of adult rat hepatocytes. J. Chromatogr. 565:1991;149-157.
    • (1991) J. Chromatogr. , vol.565 , pp. 149-157
    • Mertens, K.1    Rogiers, V.2    Sonck, W.3    Vercruysse, A.4
  • 14
    • 0026491045 scopus 로고
    • Reversed-phase chromatographic method for specific determination of glutathione in cultured malignant cells
    • Awasthi S., Ahmad F., Sharma R., Ahmad H. Reversed-phase chromatographic method for specific determination of glutathione in cultured malignant cells. J. Chromatogr. 584:1992;167-173.
    • (1992) J. Chromatogr. , vol.584 , pp. 167-173
    • Awasthi, S.1    Ahmad, F.2    Sharma, R.3    Ahmad, H.4
  • 15
    • 0029891459 scopus 로고    scopus 로고
    • Determination of reduced and oxidized glutathione in erythrocytes by high-performance liquid chromatography with ultraviolet absorbance detection
    • Yoshida T. Determination of reduced and oxidized glutathione in erythrocytes by high-performance liquid chromatography with ultraviolet absorbance detection. J. Chromatogr. B. 678:1996;157-164.
    • (1996) J. Chromatogr. B , vol.678 , pp. 157-164
    • Yoshida, T.1
  • 16
    • 0031694206 scopus 로고    scopus 로고
    • HPLC determination of glutathione and other thiols in human mononuclear blood cells
    • Raggi M.A., Mandrioli R., Casamenti G., Musiani D., Marini M. HPLC determination of glutathione and other thiols in human mononuclear blood cells. Biomed. Chromatogr. 12:1998;262-266.
    • (1998) Biomed. Chromatogr. , vol.12 , pp. 262-266
    • Raggi, M.A.1    Mandrioli, R.2    Casamenti, G.3    Musiani, D.4    Marini, M.5
  • 17
    • 0019777335 scopus 로고
    • Analysis of biological thiols with monobromobimane and separation by reverse-phase high-performance liquid chromatography
    • Newton G.L., Dorian R., Fahey R.C. Analysis of biological thiols with monobromobimane and separation by reverse-phase high-performance liquid chromatography. Anal. Biochem. 144:1981;383-387.
    • (1981) Anal. Biochem. , vol.144 , pp. 383-387
    • Newton, G.L.1    Dorian, R.2    Fahey, R.C.3
  • 18
    • 0021523466 scopus 로고
    • Trace determination of biological thiols by liquid chromatography and precolumn fluorometric labeling with o-phthalaldehyde
    • Mopper K. Trace determination of biological thiols by liquid chromatography and precolumn fluorometric labeling with o-phthalaldehyde. Anal. Chem. 56:1984;2557-2560.
    • (1984) Anal. Chem. , vol.56 , pp. 2557-2560
    • Mopper, K.1
  • 19
    • 0022818865 scopus 로고
    • Methodologies for the application of monobromobimane to the simultaneous analysis of soluble and protein thiol components of biological systems
    • Cotgreave I.A., Moldéus P. Methodologies for the application of monobromobimane to the simultaneous analysis of soluble and protein thiol components of biological systems. J. Biochem. Biophys. Methods. 13:1986;231-249.
    • (1986) J. Biochem. Biophys. Methods , vol.13 , pp. 231-249
    • Cotgreave, I.A.1    Moldéus, P.2
  • 20
    • 0023638186 scopus 로고
    • Method for determination of free and total glutathione and γ-glutamylcysteine concentrations in human leukocytes and plasma
    • Martensson J. Method for determination of free and total glutathione and γ-glutamylcysteine concentrations in human leukocytes and plasma. J. Chromatogr. 420:1987;152-157.
    • (1987) J. Chromatogr. , vol.420 , pp. 152-157
    • Martensson, J.1
  • 21
    • 0025100797 scopus 로고
    • Determination of reduced, oxidized, protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography
    • Svardal A.M., Mansoor M.A., Ueland P.M. Determination of reduced, oxidized, protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography. Anal. Biochem. 184:1990;338-346.
    • (1990) Anal. Biochem. , vol.184 , pp. 338-346
    • Svardal, A.M.1    Mansoor, M.A.2    Ueland, P.M.3
  • 22
    • 0025797088 scopus 로고
    • Fluorimetric determination of oxidized and reduced glutathione in cells and tissues by high-performance liquid chromatography following derivatization with dansyl chloride
    • Martin J., White I.H. Fluorimetric determination of oxidized and reduced glutathione in cells and tissues by high-performance liquid chromatography following derivatization with dansyl chloride. J. Chromatogr. 568:1991;219-225.
    • (1991) J. Chromatogr. , vol.568 , pp. 219-225
    • Martin, J.1    White, I.H.2
  • 23
    • 0026515778 scopus 로고
    • Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma
    • Mansoor M.A., Svardal A.M., Ueland P.M. Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma. Anal. Biochem. 200:1992;218-229.
    • (1992) Anal. Biochem. , vol.200 , pp. 218-229
    • Mansoor, M.A.1    Svardal, A.M.2    Ueland, P.M.3
  • 24
    • 0029130469 scopus 로고
    • Determination of intracellular glutathione in human skeletal muscle by reversed-phase high-performance liquid chromatography
    • Luo J.L., Hammarqvist F., Cotgreave I.A., Lind C., Andersson K., Wernerman K.J. Determination of intracellular glutathione in human skeletal muscle by reversed-phase high-performance liquid chromatography. J. Chromatogr. B. 670:1995;29-36.
    • (1995) J. Chromatogr. B , vol.670 , pp. 29-36
    • Luo, J.L.1    Hammarqvist, F.2    Cotgreave, I.A.3    Lind, C.4    Andersson, K.5    Wernerman, K.J.6
  • 25
    • 0033251995 scopus 로고    scopus 로고
    • Measurement of thiols in human plasma using liquid chromatography with precolumn derivatization and fluorescence detection
    • Salazar J.F., Schorr H., Herrmann W., Herbeth B., Siest G., Leroy P. Measurement of thiols in human plasma using liquid chromatography with precolumn derivatization and fluorescence detection. J. Chromatogr. Sci. 37:1999;469-476.
    • (1999) J. Chromatogr. Sci. , vol.37 , pp. 469-476
    • Salazar, J.F.1    Schorr, H.2    Herrmann, W.3    Herbeth, B.4    Siest, G.5    Leroy, P.6
  • 26
    • 0030298157 scopus 로고    scopus 로고
    • Speciation and quantitation of underivatized and Ellman's derivatized biological thiols and disulfides by capillary electrophoresis
    • Russell J., Rabenstein D.L. Speciation and quantitation of underivatized and Ellman's derivatized biological thiols and disulfides by capillary electrophoresis. Anal. Biochem. 242:1996;136-144.
    • (1996) Anal. Biochem. , vol.242 , pp. 136-144
    • Russell, J.1    Rabenstein, D.L.2
  • 27
  • 28
    • 0032782493 scopus 로고    scopus 로고
    • Quantitation of oxidized and reduced glutathione in plasma by micellar electrokinetic capillary electrophoresis
    • Havel K., Pritts K., Wielgos T. Quantitation of oxidized and reduced glutathione in plasma by micellar electrokinetic capillary electrophoresis. J. Chromatogr. A. 853:1999;215-223.
    • (1999) J. Chromatogr. A , vol.853 , pp. 215-223
    • Havel, K.1    Pritts, K.2    Wielgos, T.3
  • 29
    • 0032555739 scopus 로고    scopus 로고
    • Quantitation of homocysteine in human plasma by capillary electrophoresis and laser-induced fluorescence detection
    • Caussé E., Terrier R., Champagne S., Nertz M., Valdiguié P., Salvayre R., Couderc F. Quantitation of homocysteine in human plasma by capillary electrophoresis and laser-induced fluorescence detection. J. Chromatogr. A. 817:1998;181-185.
    • (1998) J. Chromatogr. A , vol.817 , pp. 181-185
    • Caussé, E.1    Terrier, R.2    Champagne, S.3    Nertz, M.4    Valdiguié, P.5    Salvayre, R.6    Couderc, F.7
  • 30
    • 0032965104 scopus 로고    scopus 로고
    • Determining sulfur-containing amino acids by capillary electrophoresis: A fast novel method for total homocyst(e)ine human plasma
    • Vecchione G., Margaglione M., Grandone E., Colaizzo D., Cappucci G., Fermo I., D'Angelo A., Di Minno G. Determining sulfur-containing amino acids by capillary electrophoresis: a fast novel method for total homocyst(e)ine human plasma. Electrophoresis. 20:1999;569-574.
    • (1999) Electrophoresis , vol.20 , pp. 569-574
    • Vecchione, G.1    Margaglione, M.2    Grandone, E.3    Colaizzo, D.4    Cappucci, G.5    Fermo, I.6    D'Angelo, A.7    Di Minno, G.8
  • 31
    • 0024582343 scopus 로고
    • Determination of plasma homocysteine by high-performance liquid chromatography with fluorescence detection
    • Jacobsen D.W., Gatautis V.J., Green R. Determination of plasma homocysteine by high-performance liquid chromatography with fluorescence detection. Anal. Biochem. 178:1989;208-214.
    • (1989) Anal. Biochem. , vol.178 , pp. 208-214
    • Jacobsen, D.W.1    Gatautis, V.J.2    Green, R.3
  • 32
    • 0029813018 scopus 로고    scopus 로고
    • Determination of plasma total homocysteine and cysteine using HPLC with fluorescence detection and an ammonium 7-fluoro-2, 1, 3-benzoxadiazole-4-sulphonate (SBD-F) derivatization protocol optimized for antioxidant concentration, derivatization reagent concentration, temperature and matrix pH
    • Daskalakis I., Lucock M.D., Anderson A., Wild J., Schorah C.J., Levene M.I. Determination of plasma total homocysteine and cysteine using HPLC with fluorescence detection and an ammonium 7-fluoro-2, 1, 3-benzoxadiazole-4-sulphonate (SBD-F) derivatization protocol optimized for antioxidant concentration, derivatization reagent concentration, temperature and matrix pH. Biomed. Chromatogr. 10:1996;205-212.
    • (1996) Biomed. Chromatogr. , vol.10 , pp. 205-212
    • Daskalakis, I.1    Lucock, M.D.2    Anderson, A.3    Wild, J.4    Schorah, C.J.5    Levene, M.I.6
  • 33
    • 0032489398 scopus 로고    scopus 로고
    • Urinary excretion measurement of cysteine and homocysteine in the form of their S-pyridinium derivatives by high-performance liquid chromatography with ultraviolet detection
    • Kaniowska E., Chwatko G., Gòwacki R., Kubalczyk P., Bald E. Urinary excretion measurement of cysteine and homocysteine in the form of their S-pyridinium derivatives by high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. A. 798:1998;27-35.
    • (1998) J. Chromatogr. A , vol.798 , pp. 27-35
    • Kaniowska, E.1    Chwatko, G.2    Gòwacki, R.3    Kubalczyk, P.4    Bald, E.5
  • 34
    • 0030858990 scopus 로고    scopus 로고
    • Quantitation of total homocysteine in human plasma by derivatization to its N(O,S)-propoxycarbonyl propyl ester and gas chromatography-mass spectrometry analysis
    • Sass J.O., Endres W. Quantitation of total homocysteine in human plasma by derivatization to its N(O,S)-propoxycarbonyl propyl ester and gas chromatography-mass spectrometry analysis. J. Chromatogr. A. 776:1997;342-347.
    • (1997) J. Chromatogr. A , vol.776 , pp. 342-347
    • Sass, J.O.1    Endres, W.2
  • 35
    • 0032988952 scopus 로고    scopus 로고
    • Gas chromatographic-mass spectrometric determination of total homocysteine in human plasma by stable isotope dilution: Method and clinical applications
    • References cited therein
    • Ducros V., Schmitt D., Pernod G., Faure H., Polack B., Favier A. Gas chromatographic-mass spectrometric determination of total homocysteine in human plasma by stable isotope dilution: method and clinical applications. J. Chromatogr. B. 729:1999;333-339. References cited therein.
    • (1999) J. Chromatogr. B , vol.729 , pp. 333-339
    • Ducros, V.1    Schmitt, D.2    Pernod, G.3    Faure, H.4    Polack, B.5    Favier, A.6
  • 36
    • 0034933062 scopus 로고    scopus 로고
    • An ion exchange liquid chromatography/mass spectrometry method for the determination of reduced and oxidized glutathione and glutathione conjugates in hepatocytes
    • Loughlin A.F., Skiles G.L., Alberts D.W., Schaefer W.H. An ion exchange liquid chromatography/mass spectrometry method for the determination of reduced and oxidized glutathione and glutathione conjugates in hepatocytes. J. Pharm. Biomed. Anal. 26:2001;131-142.
    • (2001) J. Pharm. Biomed. Anal. , vol.26 , pp. 131-142
    • Loughlin, A.F.1    Skiles, G.L.2    Alberts, D.W.3    Schaefer, W.H.4
  • 37
    • 0031900683 scopus 로고    scopus 로고
    • Atmospheric pressure ionization LC/MS/MS techniques for drug disposition studies
    • Brewer E., Henion J. Atmospheric pressure ionization LC/MS/MS techniques for drug disposition studies. J. Pharm. Sci. 87:1998;395-402.
    • (1998) J. Pharm. Sci. , vol.87 , pp. 395-402
    • Brewer, E.1    Henion, J.2
  • 40
    • 0024582343 scopus 로고
    • Determination of plasma homocysteine by high-performance liquid chromatography with fluorescence detection
    • Jacobsen D.W., Gatautis V.J., Green R. Determination of plasma homocysteine by high-performance liquid chromatography with fluorescence detection. Anal. Biochem. 178:1989;208-214.
    • (1989) Anal. Biochem. , vol.178 , pp. 208-214
    • Jacobsen, D.W.1    Gatautis, V.J.2    Green, R.3
  • 41
    • 0016437932 scopus 로고
    • Decrease in glutathione levels of kidney and liver after injection of methionine sulfoximine into rates
    • Palekar A.G., Tate S.S., Meister A. Decrease in glutathione levels of kidney and liver after injection of methionine sulfoximine into rates. Biochem. Biophys. Res. Commun. 62:1975;651-657.
    • (1975) Biochem. Biophys. Res. Commun. , vol.62 , pp. 651-657
    • Palekar, A.G.1    Tate, S.S.2    Meister, A.3
  • 42
    • 0345654274 scopus 로고
    • Glutathione: Interorgan translocation, turnover, and metabolism
    • Griffith O.W., Meister A. Glutathione: interorgan translocation, turnover, and metabolism. Proc. Natl. Acad. Sci. USA. 76:1979;5606-5610.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 5606-5610
    • Griffith, O.W.1    Meister, A.2
  • 43
    • 0017066115 scopus 로고
    • Enzyme assay for glutathione
    • Brehe J.E., Burch H.B. Enzyme assay for glutathione. Anal. Biochem. 74:1976;189-197.
    • (1976) Anal. Biochem. , vol.74 , pp. 189-197
    • Brehe, J.E.1    Burch, H.B.2


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