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Volumn 41, Issue 8, 2014, Pages 533-542

Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets

Author keywords

Angiogenesis; Cancer; Cell proliferation; NADPH oxidase; Nox; Oxidative stress; Reactive oxygen species; Superoxide

Indexed keywords

ANTIOXIDANT; OXIDOREDUCTASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; UNCLASSIFIED DRUG; VASCULOTROPIN INHIBITOR;

EID: 84906249425     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12238     Document Type: Article
Times cited : (38)

References (155)
  • 3
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 2011; 144: 646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J. What is the evidence that tumors are angiogenesis dependent? J. Natl Cancer Inst. 1990; 82: 4-6.
    • (1990) J. Natl Cancer Inst. , vol.82 , pp. 4-6
    • Folkman, J.1
  • 6
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim KJ, Li B, Winer J et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993; 362: 841-4.
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3
  • 7
    • 84876355112 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties
    • Bono F, De Smet F, Herbert C et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell 2013; 23: 477-88.
    • (2013) Cancer Cell , vol.23 , pp. 477-488
    • Bono, F.1    De Smet, F.2    Herbert, C.3
  • 9
    • 77954244182 scopus 로고    scopus 로고
    • Mechanisms contributing to cerebral infarct size after stroke: Gender, reperfusion, T lymphocytes, and Nox2-derived superoxide
    • Brait VH, Jackman KA, Walduck AK et al. Mechanisms contributing to cerebral infarct size after stroke: Gender, reperfusion, T lymphocytes, and Nox2-derived superoxide. J. Cereb. Blood Flow Metab. 2010; 30: 1306-17.
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 1306-1317
    • Brait, V.H.1    Jackman, K.A.2    Walduck, A.K.3
  • 10
    • 73549096170 scopus 로고    scopus 로고
    • Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice
    • Judkins CP, Diep H, Broughton BRS et al. Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice. Am. J. Physiol. Heart Circ. Physiol. 2010; 298: H24-32.
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.298
    • Judkins, C.P.1    Diep, H.2    Broughton, B.R.S.3
  • 11
    • 84871856593 scopus 로고    scopus 로고
    • Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation
    • Yatmaz S, Seow HJ, Gualano RC et al. Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation. Am. J. Respir. Cell Mol. Biol. 2013; 48: 17-26.
    • (2013) Am. J. Respir. Cell Mol. Biol. , vol.48 , pp. 17-26
    • Yatmaz, S.1    Seow, H.J.2    Gualano, R.C.3
  • 13
    • 84855779811 scopus 로고    scopus 로고
    • Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy
    • Vlahos R, Stambas J, Selemidis S. Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy. Trends Pharmacol. Sci. 2012; 33: 3-8.
    • (2012) Trends Pharmacol. Sci. , vol.33 , pp. 3-8
    • Vlahos, R.1    Stambas, J.2    Selemidis, S.3
  • 14
    • 0015311426 scopus 로고
    • Anti-angiogenesis: New concept for therapy of solid tumors
    • Folkman J. Anti-angiogenesis: New concept for therapy of solid tumors. Ann. Surg. 1972; 175: 409-16.
    • (1972) Ann. Surg. , vol.175 , pp. 409-416
    • Folkman, J.1
  • 16
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature 1997; 386: 671-4.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 17
    • 78650897908 scopus 로고    scopus 로고
    • Synergistic angiogenic effect of codelivering fibroblast growth factor 2 and granulocyte-colony stimulating factor from fibrin scaffolds and bone marrow transplantation in critical limb ischemia
    • Layman H, Rahnemai-Azar AA, Pham SM, Tsechpenakis G, Andreopoulos FM. Synergistic angiogenic effect of codelivering fibroblast growth factor 2 and granulocyte-colony stimulating factor from fibrin scaffolds and bone marrow transplantation in critical limb ischemia. Tissue Eng. Part A 2011; 17: 243-54.
    • (2011) Tissue Eng. Part A , vol.17 , pp. 243-254
    • Layman, H.1    Rahnemai-Azar, A.A.2    Pham, S.M.3    Tsechpenakis, G.4    Andreopoulos, F.M.5
  • 18
    • 79951539813 scopus 로고    scopus 로고
    • Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism
    • Garrido-Urbani S, Jemelin S, Deffert C et al. Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism. PLoS One 2011; 6: 2.
    • (2011) PLoS One , vol.6 , pp. 2
    • Garrido-Urbani, S.1    Jemelin, S.2    Deffert, C.3
  • 19
    • 78650367018 scopus 로고    scopus 로고
    • Deterministic and stochastic aspects of VEGF-A production and the cooperative behavior of tumoral cell colony
    • Laise P, Di Patti F, Fanelli D, Masselli M, Arcangeli A. Deterministic and stochastic aspects of VEGF-A production and the cooperative behavior of tumoral cell colony. J. Theor. Biol. 2011; 272: 55-63.
    • (2011) J. Theor. Biol. , vol.272 , pp. 55-63
    • Laise, P.1    Di Patti, F.2    Fanelli, D.3    Masselli, M.4    Arcangeli, A.5
  • 20
    • 32944463899 scopus 로고    scopus 로고
    • Angiogenesis
    • Folkman J. Angiogenesis. Annu. Rev. Med. 2006; 57: 1-18.
    • (2006) Annu. Rev. Med. , vol.57 , pp. 1-18
    • Folkman, J.1
  • 21
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • Kerbel RS. Tumor angiogenesis. N. Engl. J. Med. 2008; 358: 2039-49.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 22
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet P. Angiogenesis in health and disease. Nat. Med. 2003; 9: 653-60.
    • (2003) Nat. Med. , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 25
    • 39049165334 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth
    • Ebos JML, Lee CR, Bogdanovic E et al. Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth. Cancer Res. 2008; 68: 521-9.
    • (2008) Cancer Res. , vol.68 , pp. 521-529
    • Ebos, J.M.L.1    Lee, C.R.2    Bogdanovic, E.3
  • 27
    • 79952009484 scopus 로고    scopus 로고
    • Immunolocalization of VEGF, VEGF receptors, EGF-R and Ki-67 in leiomyoma, cellular leiomyoma and leiomyosarcoma
    • Sanci M, Dikis C, Inan S, Turkoz E, Dicle N, Ispahi C. Immunolocalization of VEGF, VEGF receptors, EGF-R and Ki-67 in leiomyoma, cellular leiomyoma and leiomyosarcoma. Acta Histochem. 2011; 113: 317-25.
    • (2011) Acta Histochem. , vol.113 , pp. 317-325
    • Sanci, M.1    Dikis, C.2    Inan, S.3    Turkoz, E.4    Dicle, N.5    Ispahi, C.6
  • 28
    • 79952771586 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-related protein 1 mediates VEGF-induced proliferation, migration and tube formation of retinal endothelial cells
    • Sun T, Cao H, Xu L, Zhu B, Gu Q, Xu X. Insulin-like growth factor binding protein-related protein 1 mediates VEGF-induced proliferation, migration and tube formation of retinal endothelial cells. Curr. Eye Res. 2011; 36: 341-9.
    • (2011) Curr. Eye Res. , vol.36 , pp. 341-349
    • Sun, T.1    Cao, H.2    Xu, L.3    Zhu, B.4    Gu, Q.5    Xu, X.6
  • 29
    • 78650611346 scopus 로고    scopus 로고
    • PET imaging of tumor angiogenesis in mice with VEGF-A-targeted 86Y-CHX-A''-DTPA-bevacizumab
    • Nayak TK, Garmestani K, Baidoo KE, Milenic DE, Brechbiel MW. PET imaging of tumor angiogenesis in mice with VEGF-A-targeted 86Y-CHX-A''-DTPA-bevacizumab. Int. J. Cancer 2011; 128: 920-6.
    • (2011) Int. J. Cancer , vol.128 , pp. 920-926
    • Nayak, T.K.1    Garmestani, K.2    Baidoo, K.E.3    Milenic, D.E.4    Brechbiel, M.W.5
  • 30
    • 79952538238 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib
    • Welti JC, Gourlaouen M, Powles T et al. Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib. Oncogene 2011; 30: 1183-93.
    • (2011) Oncogene , vol.30 , pp. 1183-1193
    • Welti, J.C.1    Gourlaouen, M.2    Powles, T.3
  • 31
  • 32
    • 78649829419 scopus 로고    scopus 로고
    • Human endothelial stem/progenitor cells, angiogenic factors and vascular repair
    • Watt SM, Athanassopoulos A, Harris AL, Tsaknakis G. Human endothelial stem/progenitor cells, angiogenic factors and vascular repair. J. R. Soc. Interface 2010; 7 (Suppl. 6): S731-51.
    • (2010) J. R. Soc. Interface , vol.7 , Issue.SUPPL. 6
    • Watt, S.M.1    Athanassopoulos, A.2    Harris, A.L.3    Tsaknakis, G.4
  • 34
    • 84887019141 scopus 로고    scopus 로고
    • Overcoming disease-induced growth factor resistance in therapeutic angiogenesis using recombinant co-receptors delivered by a liposomal system
    • Das S, Singh G, Baker AB. Overcoming disease-induced growth factor resistance in therapeutic angiogenesis using recombinant co-receptors delivered by a liposomal system. Biomaterials 2014; 35: 196-205.
    • (2014) Biomaterials , vol.35 , pp. 196-205
    • Das, S.1    Singh, G.2    Baker, A.B.3
  • 35
    • 77951279075 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer
    • Liou GY, Storz P. Reactive oxygen species in cancer. Free Radic. Res. 2010; 44: 479-96.
    • (2010) Free Radic. Res. , vol.44 , pp. 479-496
    • Liou, G.Y.1    Storz, P.2
  • 36
    • 0342573147 scopus 로고
    • Free radicals mediate endothelial dysfunction of coronary arterioles in diabetes
    • Ammar RF, Gutterman DD, Brooks LA, Dellsperger KC. Free radicals mediate endothelial dysfunction of coronary arterioles in diabetes. Cardiovasc. Res. 1970; 4: 595-601.
    • (1970) Cardiovasc. Res. , vol.4 , pp. 595-601
    • Ammar, R.F.1    Gutterman, D.D.2    Brooks, L.A.3    Dellsperger, K.C.4
  • 38
    • 79955603018 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo
    • Zhao MM, Xu MJ, Cai Y et al. Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo. Kidney Int. 2011; 79: 1071-9.
    • (2011) Kidney Int. , vol.79 , pp. 1071-1079
    • Zhao, M.M.1    Xu, M.J.2    Cai, Y.3
  • 39
  • 40
    • 79551621417 scopus 로고    scopus 로고
    • Autophagy, reactive oxygen species and the fate of mammalian cells
    • Szumiel I. Autophagy, reactive oxygen species and the fate of mammalian cells. Free Radic. Res. 2011; 45: 253-65.
    • (2011) Free Radic. Res. , vol.45 , pp. 253-265
    • Szumiel, I.1
  • 41
    • 79952116012 scopus 로고    scopus 로고
    • Pro-inflammatory angiogenesis is mediated by p38 MAP kinase
    • Rajashekhar G, Kamocka M, Marin A et al. Pro-inflammatory angiogenesis is mediated by p38 MAP kinase. J. Cell. Physiol. 2011; 226: 800-8.
    • (2011) J. Cell. Physiol. , vol.226 , pp. 800-808
    • Rajashekhar, G.1    Kamocka, M.2    Marin, A.3
  • 42
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • Pelicano H, Carney D, Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist. Updat. 2004; 7: 97-110.
    • (2004) Drug Resist. Updat. , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 43
    • 33847683419 scopus 로고    scopus 로고
    • Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage
    • Indo HP, Davidson M, Yen H-C et al. Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage. Mitochondrion 2007; 7: 106-18.
    • (2007) Mitochondrion , vol.7 , pp. 106-118
    • Indo, H.P.1    Davidson, M.2    Yen, H.-C.3
  • 44
    • 0037306073 scopus 로고    scopus 로고
    • Editorial: Emerging concepts in the management of prostatitis/chronic pelvic pain syndrome
    • Schaeffer AJ. Editorial: Emerging concepts in the management of prostatitis/chronic pelvic pain syndrome. J. Urol. 2003; 169: 597-8.
    • (2003) J. Urol. , vol.169 , pp. 597-598
    • Schaeffer, A.J.1
  • 45
  • 46
    • 0142028110 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress and mitochondrial DNA
    • Kang D, Hamasaki N. Mitochondrial oxidative stress and mitochondrial DNA. Clin. Chem. Lab. Med. 2003; 41: 1281-8.
    • (2003) Clin. Chem. Lab. Med. , vol.41 , pp. 1281-1288
    • Kang, D.1    Hamasaki, N.2
  • 47
    • 0028900690 scopus 로고
    • Persistent oxidative stress in cancer
    • Toyokuni S. Persistent oxidative stress in cancer. FEBS Lett. 1995; 358: 1-3.
    • (1995) FEBS Lett. , vol.358 , pp. 1-3
    • Toyokuni, S.1
  • 48
    • 0026352795 scopus 로고
    • Free radicals in chemical carcinogenesis
    • Clemens MR. Free radicals in chemical carcinogenesis. Klin. Wochenschr. 1991; 69: 1123-34.
    • (1991) Klin. Wochenschr. , vol.69 , pp. 1123-1134
    • Clemens, M.R.1
  • 49
    • 34249071326 scopus 로고    scopus 로고
    • VEGF signaling through NADPH oxidase-derived ROS
    • Ushio-Fukai M. VEGF signaling through NADPH oxidase-derived ROS. Antioxid. Redox Signal. 2007; 9: 731-9.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 731-739
    • Ushio-Fukai, M.1
  • 52
    • 0028871420 scopus 로고
    • Superoxide and the production of oxidative DNA damage
    • Keyer K, Gort AS, Imlay JA. Superoxide and the production of oxidative DNA damage. J. Bacteriol. 1995; 177: 6782-90.
    • (1995) J. Bacteriol. , vol.177 , pp. 6782-6790
    • Keyer, K.1    Gort, A.S.2    Imlay, J.A.3
  • 53
    • 0017149747 scopus 로고
    • The alteration of superoxide dismutase, catalase, glutathione peroxidase, and NAD(P)H cytochrome c reductase in guinea pig polymorphonuclear leukocytes and alveolar macrophages during hyperoxia
    • Rister M, Baehner RL. The alteration of superoxide dismutase, catalase, glutathione peroxidase, and NAD(P)H cytochrome c reductase in guinea pig polymorphonuclear leukocytes and alveolar macrophages during hyperoxia. J. Clin. Invest. 1976; 58: 1174-84.
    • (1976) J. Clin. Invest. , vol.58 , pp. 1174-1184
    • Rister, M.1    Baehner, R.L.2
  • 54
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • Nishikawa T, Edelstein D, Du XL et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000; 404: 787-90.
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3
  • 55
    • 77949896128 scopus 로고    scopus 로고
    • Peroxynitrite-dependent killing of cancer cells and presentation of released tumor antigens by activated dendritic cells
    • Fraszczak J, Trad M, Janikashvili N et al. Peroxynitrite-dependent killing of cancer cells and presentation of released tumor antigens by activated dendritic cells. J. Immunol. 2010; 184: 1876-84.
    • (2010) J. Immunol. , vol.184 , pp. 1876-1884
    • Fraszczak, J.1    Trad, M.2    Janikashvili, N.3
  • 56
    • 46749092519 scopus 로고    scopus 로고
    • Ischemic and peroxynitrite preconditioning effects in chronic hypoxic rat lung
    • Turan NN, Yildiz G, Gumusel B, Demiryurek AT. Ischemic and peroxynitrite preconditioning effects in chronic hypoxic rat lung. Exp. Lung Res. 2008; 34: 325-41.
    • (2008) Exp. Lung Res. , vol.34 , pp. 325-341
    • Turan, N.N.1    Yildiz, G.2    Gumusel, B.3    Demiryurek, A.T.4
  • 57
    • 0036285223 scopus 로고    scopus 로고
    • Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels
    • Guzik TJ, West NEJ, Pillai R, Taggart DP, Channon KM. Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels. Hypertension 2002; 39: 1088-94.
    • (2002) Hypertension , vol.39 , pp. 1088-1094
    • Guzik, T.J.1    West, N.E.J.2    Pillai, R.3    Taggart, D.P.4    Channon, K.M.5
  • 59
    • 0014962562 scopus 로고
    • Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase
    • Fridovich I. Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J. Biol. Chem. 1970; 245: 4053-7.
    • (1970) J. Biol. Chem. , vol.245 , pp. 4053-4057
    • Fridovich, I.1
  • 60
    • 0014691242 scopus 로고
    • Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
    • McCord JM, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem. 1969; 244: 6049-55.
    • (1969) J. Biol. Chem. , vol.244 , pp. 6049-6055
    • McCord, J.M.1    Fridovich, I.2
  • 61
    • 0022260427 scopus 로고
    • Diffusion of extracellular hydrogen peroxide into intracellular compartments of human neutrophils: Studies utilizing the inactivation of myeloperoxidase by hydrogen peroxide and azide
    • Ohno Y, Gallin JI. Diffusion of extracellular hydrogen peroxide into intracellular compartments of human neutrophils: Studies utilizing the inactivation of myeloperoxidase by hydrogen peroxide and azide. J. Biol. Chem. 1985; 260: 8438-46.
    • (1985) J. Biol. Chem. , vol.260 , pp. 8438-8446
    • Ohno, Y.1    Gallin, J.I.2
  • 62
    • 0034793688 scopus 로고    scopus 로고
    • The Haber-Weiss cycle: 70 years later
    • Koppenol WH. The Haber-Weiss cycle: 70 years later. Redox Rep. 2001; 6: 229-34.
    • (2001) Redox Rep. , vol.6 , pp. 229-234
    • Koppenol, W.H.1
  • 63
    • 33750299450 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases: From genes, to function, to disease
    • Tonks NK. Protein tyrosine phosphatases: From genes, to function, to disease. Nat. Rev. Mol. Cell Biol. 2006; 7: 833-46.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 833-846
    • Tonks, N.K.1
  • 65
    • 2942581416 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases in the human genome
    • Alonso A, Sasin J, Bottini N et al. Protein tyrosine phosphatases in the human genome. Cell 2004; 117: 699-711.
    • (2004) Cell , vol.117 , pp. 699-711
    • Alonso, A.1    Sasin, J.2    Bottini, N.3
  • 66
    • 84873043542 scopus 로고    scopus 로고
    • TCPTP regulates SFK, STAT3 signaling and is lost in triple-negative breast cancers
    • Shields BJ, Wiede F, Gurzov EN et al. TCPTP regulates SFK, STAT3 signaling and is lost in triple-negative breast cancers. Mol. Cell. Biol. 2013; 33: 557-70.
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 557-570
    • Shields, B.J.1    Wiede, F.2    Gurzov, E.N.3
  • 67
    • 84872787813 scopus 로고    scopus 로고
    • Methods to monitor classical protein-tyrosine phosphatase oxidation
    • Karisch R, Neel BG. Methods to monitor classical protein-tyrosine phosphatase oxidation. FEBS J. 2013; 280: 459-75.
    • (2013) FEBS J. , vol.280 , pp. 459-475
    • Karisch, R.1    Neel, B.G.2
  • 68
    • 2542559631 scopus 로고    scopus 로고
    • Mechanistic studies on protein tyrosine phosphatases
    • Zhang ZY. Mechanistic studies on protein tyrosine phosphatases. Prog. Nucleic Acid Res. Mol. Biol. 2003; 73: 171-220.
    • (2003) Prog. Nucleic Acid Res. Mol. Biol. , vol.73 , pp. 171-220
    • Zhang, Z.Y.1
  • 70
    • 20444400257 scopus 로고    scopus 로고
    • Redox redux: Revisiting PTPs and the control of cell signaling
    • Tonks NK. Redox redux: Revisiting PTPs and the control of cell signaling. Cell 2005; 121: 667-70.
    • (2005) Cell , vol.121 , pp. 667-670
    • Tonks, N.K.1
  • 71
    • 77950944395 scopus 로고    scopus 로고
    • Macrophages, innate immunity and cancer: Balance, tolerance, and diversity
    • Mantovani A, Sica A. Macrophages, innate immunity and cancer: Balance, tolerance, and diversity. Curr. Opin. Immunol. 2010; 22: 231-7.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 231-237
    • Mantovani, A.1    Sica, A.2
  • 72
    • 84880289368 scopus 로고    scopus 로고
    • The involvement of Helicobacter pylori thioredoxin-1 in gastric carcinogenesis
    • Shi Y, Liu L, Zhang T et al. The involvement of Helicobacter pylori thioredoxin-1 in gastric carcinogenesis. J. Med. Microbiol. 2013; 62: 1226-34.
    • (2013) J. Med. Microbiol. , vol.62 , pp. 1226-1234
    • Shi, Y.1    Liu, L.2    Zhang, T.3
  • 73
    • 0036294342 scopus 로고    scopus 로고
    • Epidemiologic association between prostatitis and prostate cancer
    • Dennis LK, Lynch CF, Torner JC. Epidemiologic association between prostatitis and prostate cancer. Urology 2002; 60: 78-83.
    • (2002) Urology , vol.60 , pp. 78-83
    • Dennis, L.K.1    Lynch, C.F.2    Torner, J.C.3
  • 76
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell 2010; 141: 39-51.
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 77
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • Condeelis J, Pollard JW. Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006; 124: 263-6.
    • (2006) Cell , vol.124 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 78
    • 84859853336 scopus 로고    scopus 로고
    • NADPH oxidases as regulators of tumor angiogenesis: Current and emerging concepts
    • Coso S, Harrison I, Harrison CB et al. NADPH oxidases as regulators of tumor angiogenesis: Current and emerging concepts. Antioxid. Redox Signal. 2012; 16: 1229-47.
    • (2012) Antioxid. Redox Signal. , vol.16 , pp. 1229-1247
    • Coso, S.1    Harrison, I.2    Harrison, C.B.3
  • 79
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 2004; 10: 942-9.
    • (2004) Nat. Med. , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 80
    • 79251539881 scopus 로고    scopus 로고
    • Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells
    • Efimova O, Szankasi P, Kelley TW. Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells. PLoS One 2011; 6: 1.
    • (2011) PLoS One , vol.6 , pp. 1
    • Efimova, O.1    Szankasi, P.2    Kelley, T.W.3
  • 81
    • 79959333447 scopus 로고    scopus 로고
    • Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells
    • Lee K, Won HY, Bae MA, Hong JH, Hwang ES. Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells. Proc. Natl Acad. Sci. USA 2011; 108: 9548-53.
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 9548-9553
    • Lee, K.1    Won, H.Y.2    Bae, M.A.3    Hong, J.H.4    Hwang, E.S.5
  • 82
  • 83
    • 0034234580 scopus 로고    scopus 로고
    • Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer
    • Bostwick DG, Alexander EE, Singh R et al. Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer. Cancer 2000; 89: 123-34.
    • (2000) Cancer , vol.89 , pp. 123-134
    • Bostwick, D.G.1    Alexander, E.E.2    Singh, R.3
  • 84
    • 0345255906 scopus 로고    scopus 로고
    • Role of oxidative stress response elements and antioxidants in prostate cancer pathobiology and chemoprevention: A mechanistic approach
    • Sikka SC. Role of oxidative stress response elements and antioxidants in prostate cancer pathobiology and chemoprevention: A mechanistic approach. Curr. Med. Chem. 2003; 10: 2679-92.
    • (2003) Curr. Med. Chem. , vol.10 , pp. 2679-2692
    • Sikka, S.C.1
  • 85
    • 0032845512 scopus 로고    scopus 로고
    • N-Acetylcysteine inhibits endothelial cell invasion and angiogenesis
    • Cai T, Fassina G, Morini M et al. N-Acetylcysteine inhibits endothelial cell invasion and angiogenesis. Lab. Invest. 1999; 79: 1151-9.
    • (1999) Lab. Invest. , vol.79 , pp. 1151-1159
    • Cai, T.1    Fassina, G.2    Morini, M.3
  • 86
    • 0037129803 scopus 로고    scopus 로고
    • Phosphorylation of p47phox sites by PKCα, βII, δ and ζ: Effect on binding to p22phox and on NADPH oxidase activation
    • Fontayne A, Dang PMC, Gougerot-Pocidalo MA, El Benna J. Phosphorylation of p47phox sites by PKCα, βII, δ and ζ: Effect on binding to p22phox and on NADPH oxidase activation. Biochemistry 2002; 41: 7743-50.
    • (2002) Biochemistry , vol.41 , pp. 7743-7750
    • Fontayne, A.1    Dang, P.M.C.2    Gougerot-Pocidalo, M.A.3    El Benna, J.4
  • 87
    • 77956813371 scopus 로고    scopus 로고
    • Comparative pharmacology of chemically distinct NADPH oxidase inhibitors
    • Wind S, Beuerlein K, Eucker T et al. Comparative pharmacology of chemically distinct NADPH oxidase inhibitors. Br. J. Pharmacol. 2010; 161: 885-98.
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 885-898
    • Wind, S.1    Beuerlein, K.2    Eucker, T.3
  • 88
    • 0346257893 scopus 로고    scopus 로고
    • The role of antioxidants in cancer prevention and treatment
    • Sardas S. The role of antioxidants in cancer prevention and treatment. Indoor Built Environ. 2003; 12: 401-4.
    • (2003) Indoor Built Environ. , vol.12 , pp. 401-404
    • Sardas, S.1
  • 89
    • 77956650750 scopus 로고    scopus 로고
    • Antioxidants: Benefits and risks for long-term health
    • Yoshihara D, Fujiwara N, Suzuki K. Antioxidants: Benefits and risks for long-term health. Maturitas 2010; 67: 103-7.
    • (2010) Maturitas , vol.67 , pp. 103-107
    • Yoshihara, D.1    Fujiwara, N.2    Suzuki, K.3
  • 90
    • 0035964175 scopus 로고    scopus 로고
    • Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols
    • Gupta S, Hastak K, Ahmad N, Lewin JS, Mukhtar H. Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc. Natl Acad. Sci. USA 2001; 98: 10350-5.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 10350-10355
    • Gupta, S.1    Hastak, K.2    Ahmad, N.3    Lewin, J.S.4    Mukhtar, H.5
  • 91
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology. Physiol. Rev. 2007; 87: 245-313.
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 92
    • 79957890939 scopus 로고    scopus 로고
    • Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
    • Drummond GR, Selemidis S, Griendling KK, Sobey CG. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat. Rev. Drug Discov. 2011; 10: 453-71.
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 453-471
    • Drummond, G.R.1    Selemidis, S.2    Griendling, K.K.3    Sobey, C.G.4
  • 93
    • 56149093044 scopus 로고    scopus 로고
    • NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition
    • Selemidis S, Sobey CG, Wingler K, Schmidt HHHW, Drummond GR. NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition. Pharmacol. Ther. 2008; 120: 254-91.
    • (2008) Pharmacol. Ther. , vol.120 , pp. 254-291
    • Selemidis, S.1    Sobey, C.G.2    Wingler, K.3    Schmidt, H.H.H.W.4    Drummond, G.R.5
  • 94
    • 84876500601 scopus 로고    scopus 로고
    • Opportunity Nox: The future of NADPH oxidases as therapeutic targets in cardiovascular disease
    • Streeter J, Thiel W, Brieger K, Miller FJ Jr. Opportunity Nox: The future of NADPH oxidases as therapeutic targets in cardiovascular disease. Cardiovasc. Ther. 2013; 31: 125-37.
    • (2013) Cardiovasc. Ther. , vol.31 , pp. 125-137
    • Streeter, J.1    Thiel, W.2    Brieger, K.3    Miller Jr., F.J.4
  • 95
    • 84893825263 scopus 로고    scopus 로고
    • Nox family NADPH oxidases in mechano-transduction: Mechanisms and consequences
    • Brandes RP, Weissmann N, Schroder K. Nox family NADPH oxidases in mechano-transduction: Mechanisms and consequences. Antioxid. Redox Signal. 2014; 20: 887-98.
    • (2014) Antioxid. Redox Signal. , vol.20 , pp. 887-898
    • Brandes, R.P.1    Weissmann, N.2    Schroder, K.3
  • 96
    • 79251546780 scopus 로고    scopus 로고
    • NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats
    • Khan SA, Nanduri J, Yuan G et al. NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats. Antioxid. Redox Signal. 2011; 14: 533-42.
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 533-542
    • Khan, S.A.1    Nanduri, J.2    Yuan, G.3
  • 97
    • 33750913836 scopus 로고    scopus 로고
    • Physiology and pathophysiology of the DUOXes
    • Ris-Stalpers C. Physiology and pathophysiology of the DUOXes. Antioxid. Redox Signal. 2006; 8: 1563-72.
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 1563-1572
    • Ris-Stalpers, C.1
  • 98
  • 99
    • 13844276168 scopus 로고    scopus 로고
    • Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells
    • Goyal P, Weissmann N, Rose F et al. Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells. Biochem. Biophys. Res. Commun. 2005; 329: 32-9.
    • (2005) Biochem. Biophys. Res. Commun. , vol.329 , pp. 32-39
    • Goyal, P.1    Weissmann, N.2    Rose, F.3
  • 100
    • 84875371364 scopus 로고    scopus 로고
    • A 28-kDa splice variant of NADPH oxidase-4 is nuclear-localized and involved in redox signaling in vascular cells
    • Anilkumar N, Jose GS, Sawyer I et al. A 28-kDa splice variant of NADPH oxidase-4 is nuclear-localized and involved in redox signaling in vascular cells. Arterioscler. Thromb. Vasc. Biol. 2013; 33: e104-12.
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33
    • Anilkumar, N.1    Jose, G.S.2    Sawyer, I.3
  • 101
    • 0032487361 scopus 로고    scopus 로고
    • Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+
    • Al-Mehdi AB, Zhao G, Dodia C et al. Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+. Circ. Res. 1998; 83: 730-7.
    • (1998) Circ. Res. , vol.83 , pp. 730-737
    • Al-Mehdi, A.B.1    Zhao, G.2    Dodia, C.3
  • 102
    • 0032104153 scopus 로고    scopus 로고
    • Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: Role of a superoxide-producing NADH oxidase
    • De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Wayne Alexander R, Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: Role of a superoxide-producing NADH oxidase. Circ. Res. 1998; 82: 1094-101.
    • (1998) Circ. Res. , vol.82 , pp. 1094-1101
    • De Keulenaer, G.W.1    Chappell, D.C.2    Ishizaka, N.3    Nerem, R.M.4    Wayne Alexander, R.5    Griendling, K.K.6
  • 103
    • 60749137151 scopus 로고    scopus 로고
    • NADPH oxidase-dependent signaling in endothelial cells: Role in physiology and pathophysiology
    • Frey RS, Ushio-Fukai M, Malik AB. NADPH oxidase-dependent signaling in endothelial cells: Role in physiology and pathophysiology. Antioxid. Redox Signal. 2009; 11: 791-810.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 791-810
    • Frey, R.S.1    Ushio-Fukai, M.2    Malik, A.B.3
  • 104
    • 0034617071 scopus 로고    scopus 로고
    • A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
    • Görlach A, Brandes RP, Nguyen K, Amidi M, Dehghani F, Busse R. A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall. Circ. Res. 2000; 87: 26-32.
    • (2000) Circ. Res. , vol.87 , pp. 26-32
    • Görlach, A.1    Brandes, R.P.2    Nguyen, K.3    Amidi, M.4    Dehghani, F.5    Busse, R.6
  • 105
    • 34547850670 scopus 로고    scopus 로고
    • NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
    • Serrander L, Cartier L, Bedard K et al. NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. Biochem. J. 2007; 406: 105-14.
    • (2007) Biochem. J. , vol.406 , pp. 105-114
    • Serrander, L.1    Cartier, L.2    Bedard, K.3
  • 106
    • 67449116322 scopus 로고    scopus 로고
    • NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival
    • Peshavariya H, Dusting GJ, Jiang F et al. NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival. Naunyn Schmiedebergs Arch. Pharmacol. 2009; 380: 193-204.
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.380 , pp. 193-204
    • Peshavariya, H.1    Dusting, G.J.2    Jiang, F.3
  • 107
    • 5344232726 scopus 로고    scopus 로고
    • Functional association of Nox1 with p22phox in vascular smooth muscle cells
    • Hanna IR, Hilenski LL, Dikalova A et al. Functional association of Nox1 with p22phox in vascular smooth muscle cells. Free Radic. Biol. Med. 2004; 37: 1542-9.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 1542-1549
    • Hanna, I.R.1    Hilenski, L.L.2    Dikalova, A.3
  • 108
    • 80051968584 scopus 로고    scopus 로고
    • In search of new therapeutic targets and strategies for heart failure: Recent advances in basic science
    • Shah AM, Mann DL. In search of new therapeutic targets and strategies for heart failure: Recent advances in basic science. Lancet 2011; 378: 704-12.
    • (2011) Lancet , vol.378 , pp. 704-712
    • Shah, A.M.1    Mann, D.L.2
  • 109
    • 84884164413 scopus 로고    scopus 로고
    • CXCR3, a double-edged sword in tumor progression and angiogenesis
    • Billottet C, Quemener C, Bikfalvi A. CXCR3, a double-edged sword in tumor progression and angiogenesis. Biochim. Biophys. Acta 2013; 1836: 287-95.
    • (2013) Biochim. Biophys. Acta , vol.1836 , pp. 287-295
    • Billottet, C.1    Quemener, C.2    Bikfalvi, A.3
  • 110
    • 84894574261 scopus 로고    scopus 로고
    • Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization
    • Wang H, Jiang Y, Shi D et al. Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization. FASEB J. 2014; 28: 265-74.
    • (2014) FASEB J. , vol.28 , pp. 265-274
    • Wang, H.1    Jiang, Y.2    Shi, D.3
  • 111
    • 84893189117 scopus 로고    scopus 로고
    • Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes
    • Daugaard M, Nitsch R, Razaghi B et al. Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes. Nat. Commun. 2013; 4: 2180.
    • (2013) Nat. Commun. , vol.4 , pp. 2180
    • Daugaard, M.1    Nitsch, R.2    Razaghi, B.3
  • 112
    • 84868096004 scopus 로고    scopus 로고
    • NADPH oxidase 4 mediates insulin-stimulated HIF-1α and VEGF expression, and angiogenesis in vitro
    • Meng D, Mei A, Liu J et al. NADPH oxidase 4 mediates insulin-stimulated HIF-1α and VEGF expression, and angiogenesis in vitro. PLoS One 2012; 7: 10.
    • (2012) PLoS One , vol.7 , pp. 10
    • Meng, D.1    Mei, A.2    Liu, J.3
  • 113
    • 0036954803 scopus 로고    scopus 로고
    • Novel role of gp91phox-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis
    • Ushio-Fukai M, Tang Y, Fukai T et al. Novel role of gp91phox-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ. Res. 2002; 91: 1160-7.
    • (2002) Circ. Res. , vol.91 , pp. 1160-1167
    • Ushio-Fukai, M.1    Tang, Y.2    Fukai, T.3
  • 114
    • 0037154250 scopus 로고    scopus 로고
    • Reactive oxygen generated by Nox1 triggers the angiogenic switch
    • Arbiser JL, Petros J, Klafter R et al. Reactive oxygen generated by Nox1 triggers the angiogenic switch. Proc. Natl Acad. Sci. USA 2002; 99: 715-20.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 715-720
    • Arbiser, J.L.1    Petros, J.2    Klafter, R.3
  • 115
    • 84875983841 scopus 로고    scopus 로고
    • Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress
    • Selemidis S, Seow HJ, Broughton BR et al. Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress. PLoS One 2013; 8: 8.
    • (2013) PLoS One , vol.8 , pp. 8
    • Selemidis, S.1    Seow, H.J.2    Broughton, B.R.3
  • 116
    • 18544377867 scopus 로고    scopus 로고
    • Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols
    • Johnson DK, Schillinger KJ, Kwait DM et al. Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols. Endothelium 2002; 9: 191-203.
    • (2002) Endothelium , vol.9 , pp. 191-203
    • Johnson, D.K.1    Schillinger, K.J.2    Kwait, D.M.3
  • 117
    • 84883170266 scopus 로고    scopus 로고
    • Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis
    • Kinkade K, Streeter J, Miller FJ Jr. Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis. Int. J. Mol. Sci. 2013; 14: 17017-28.
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 17017-17028
    • Kinkade, K.1    Streeter, J.2    Miller Jr., F.J.3
  • 118
    • 0028473441 scopus 로고
    • Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol
    • Stolk J, Hiltermann T, Dijkman J, Verhoeven A. Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol. Am. J. Respir. Cell Mol. Biol. 1994; 11: 95-102.
    • (1994) Am. J. Respir. Cell Mol. Biol. , vol.11 , pp. 95-102
    • Stolk, J.1    Hiltermann, T.2    Dijkman, J.3    Verhoeven, A.4
  • 119
    • 0028104549 scopus 로고
    • Involvement of phenyl radicals in lodonium compound inhibition of flavoenzymes
    • O'Donnell VB, Smith GCM, Jones OTG. Involvement of phenyl radicals in lodonium compound inhibition of flavoenzymes. Mol. Pharmacol. 1994; 46: 778-85.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 778-785
    • O'Donnell, V.B.1    Smith, G.C.M.2    Jones, O.T.G.3
  • 120
    • 0035980160 scopus 로고    scopus 로고
    • Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O2- and systolic blood pressure in mice
    • Rey FE, Cifuentes ME, Kiarash A, Quinn MT, Pagano PJ. Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O2- and systolic blood pressure in mice. Circ. Res. 2001; 89: 408-14.
    • (2001) Circ. Res. , vol.89 , pp. 408-414
    • Rey, F.E.1    Cifuentes, M.E.2    Kiarash, A.3    Quinn, M.T.4    Pagano, P.J.5
  • 121
    • 80051802409 scopus 로고    scopus 로고
    • Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2
    • Csányi G, Cifuentes-Pagano E, Al Ghouleh I et al. Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2. Free Radic. Biol. Med. 2011; 51: 1116-25.
    • (2011) Free Radic. Biol. Med. , vol.51 , pp. 1116-1125
    • Csányi, G.1    Cifuentes-Pagano, E.2    Al Ghouleh, I.3
  • 122
    • 84901054437 scopus 로고    scopus 로고
    • Sly as a Nox: The challenges, triumphs and pitfalls of selective NADPH oxidase inhibition
    • doi: 10.1089/ars.2013.5620.
    • Cifuentes-Pagano E, Meijles D, Pagano PJ. Sly as a Nox: The challenges, triumphs and pitfalls of selective NADPH oxidase inhibition. Antioxid. Redox Signal. 2014; doi: 10.1089/ars.2013.5620.
    • (2014) Antioxid. Redox Signal.
    • Cifuentes-Pagano, E.1    Meijles, D.2    Pagano, P.J.3
  • 123
    • 33748761640 scopus 로고    scopus 로고
    • Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice
    • Perry BN, Govindarajan B, Bhandarkar SS et al. Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice. J. Invest. Dermatol. 2006; 126: 2316-22.
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 2316-2322
    • Perry, B.N.1    Govindarajan, B.2    Bhandarkar, S.S.3
  • 124
    • 68849104002 scopus 로고    scopus 로고
    • Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice
    • Bhandarkar SS, Jaconi M, Fried LE et al. Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice. J. Clin. Invest. 2009; 119: 2359-65.
    • (2009) J. Clin. Invest. , vol.119 , pp. 2359-2365
    • Bhandarkar, S.S.1    Jaconi, M.2    Fried, L.E.3
  • 125
    • 0028136243 scopus 로고
    • Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione
    • Schewe C, Schewe T, Wendel A. Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione. Biochem. Pharmacol. 1994; 48: 65-74.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 65-74
    • Schewe, C.1    Schewe, T.2    Wendel, A.3
  • 126
    • 0028335529 scopus 로고
    • Effects of ebselen and probucol on oxidative modifications of lipid and protein of low density lipoprotein induced by free radicals
    • Noguchi N, Gotoh N, Niki E. Effects of ebselen and probucol on oxidative modifications of lipid and protein of low density lipoprotein induced by free radicals. Biochim. Biophys. Acta 1994; 1213: 176-82.
    • (1994) Biochim. Biophys. Acta , vol.1213 , pp. 176-182
    • Noguchi, N.1    Gotoh, N.2    Niki, E.3
  • 127
    • 84862743816 scopus 로고    scopus 로고
    • Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits
    • Smith SME, Min J, Ganesh T et al. Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. Chem. Biol. 2012; 19: 752-63.
    • (2012) Chem. Biol. , vol.19 , pp. 752-763
    • Smith, S.M.E.1    Min, J.2    Ganesh, T.3
  • 128
    • 84861529165 scopus 로고    scopus 로고
    • Divergent effects of p47 phox phosphorylation at S303-4 or S379 on tumor necrosis factor-α signaling via TRAF4 and MAPK in endothelial cells
    • Teng L, Fan LM, Meijles D, Li JM. Divergent effects of p47 phox phosphorylation at S303-4 or S379 on tumor necrosis factor-α signaling via TRAF4 and MAPK in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 2012; 32: 1488-96.
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 1488-1496
    • Teng, L.1    Fan, L.M.2    Meijles, D.3    Li, J.M.4
  • 129
    • 77958098686 scopus 로고    scopus 로고
    • A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells
    • Gianni D, Taulet N, Zhang H et al. A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. ACS Chem. Biol. 2010; 5: 981-93.
    • (2010) ACS Chem. Biol. , vol.5 , pp. 981-993
    • Gianni, D.1    Taulet, N.2    Zhang, H.3
  • 130
    • 84864330120 scopus 로고    scopus 로고
    • NADPH oxidases as therapeutic targets in ischemic stroke
    • Kahles T, Brandes RP. NADPH oxidases as therapeutic targets in ischemic stroke. Cell. Mol. Life Sci. 2012; 69: 2345-63.
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 2345-2363
    • Kahles, T.1    Brandes, R.P.2
  • 131
    • 84864360259 scopus 로고    scopus 로고
    • The NOX toolbox: Validating the role of NADPH oxidases in physiology and disease
    • Altenhöfer S, Kleikers PWM, Radermacher KA et al. The NOX toolbox: Validating the role of NADPH oxidases in physiology and disease. Cell. Mol. Life Sci. 2012; 69: 2327-43.
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 2327-2343
    • Altenhöfer, S.1    Kleikers, P.W.M.2    Radermacher, K.A.3
  • 133
    • 79952575436 scopus 로고    scopus 로고
    • The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells
    • Sancho P, Fabregat I. The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells. Biochem. Pharmacol. 2011; 81: 917-24.
    • (2011) Biochem. Pharmacol. , vol.81 , pp. 917-924
    • Sancho, P.1    Fabregat, I.2
  • 134
    • 78649913769 scopus 로고    scopus 로고
    • Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: Implications in type 2 diabetic nephropathy
    • Sedeek M, Callera G, Montezano A et al. Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: Implications in type 2 diabetic nephropathy. Am. J. Physiol. Renal Physiol. 2010; 299: F1348-58.
    • (2010) Am. J. Physiol. Renal Physiol. , vol.299
    • Sedeek, M.1    Callera, G.2    Montezano, A.3
  • 135
    • 84868315535 scopus 로고    scopus 로고
    • The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation
    • Green DE, Murphy TC, Kang BY et al. The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation. Am. J. Respir. Cell Mol. Biol. 2012; 47: 718-26.
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.47 , pp. 718-726
    • Green, D.E.1    Murphy, T.C.2    Kang, B.Y.3
  • 136
    • 0035724983 scopus 로고    scopus 로고
    • S17834, a new inhibitor of cell adhesion and atherosclerosis that targets NADPH oxidase
    • Cayatte AJ, Rupin A, Oliver-Krasinski J et al. S17834, a new inhibitor of cell adhesion and atherosclerosis that targets NADPH oxidase. Arterioscler. Thromb. Vasc. Biol. 2001; 21: 1577-84.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 1577-1584
    • Cayatte, A.J.1    Rupin, A.2    Oliver-Krasinski, J.3
  • 138
    • 67650917886 scopus 로고    scopus 로고
    • Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues
    • Juhasz A, Ge Y, Markel S et al. Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues. Free Radic. Res. 2009; 43: 523-32.
    • (2009) Free Radic. Res. , vol.43 , pp. 523-532
    • Juhasz, A.1    Ge, Y.2    Markel, S.3
  • 139
    • 66149156967 scopus 로고    scopus 로고
    • A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression
    • Shimada K, Nakamura M, Anai S et al. A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression. Cancer Res. 2009; 69: 3157-64.
    • (2009) Cancer Res. , vol.69 , pp. 3157-3164
    • Shimada, K.1    Nakamura, M.2    Anai, S.3
  • 140
    • 31144469322 scopus 로고    scopus 로고
    • Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors
    • Desouki MM, Kulawiec M, Bansal S, Das G, Singh KK. Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors. Cancer Biol. Ther. 2005; 4: 1367-73.
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 1367-1373
    • Desouki, M.M.1    Kulawiec, M.2    Bansal, S.3    Das, G.4    Singh, K.K.5
  • 141
    • 77952079054 scopus 로고    scopus 로고
    • The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberin
    • Block K, Gorin Y, New DD et al. The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberin. Am. J. Pathol. 2010; 176: 2447-55.
    • (2010) Am. J. Pathol. , vol.176 , pp. 2447-2455
    • Block, K.1    Gorin, Y.2    New, D.D.3
  • 142
    • 38349004555 scopus 로고    scopus 로고
    • Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1
    • Arnold RS, He J, Remo A et al. Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1. Am. J. Pathol. 2007; 171: 2021-32.
    • (2007) Am. J. Pathol. , vol.171 , pp. 2021-2032
    • Arnold, R.S.1    He, J.2    Remo, A.3
  • 143
    • 84866425239 scopus 로고    scopus 로고
    • Aiding and abetting roles of NOX oxidases in cellular transformation
    • Block K, Gorin Y. Aiding and abetting roles of NOX oxidases in cellular transformation. Nat. Rev. Cancer 2012; 12: 627-37.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 627-637
    • Block, K.1    Gorin, Y.2
  • 144
  • 145
    • 40949159866 scopus 로고    scopus 로고
    • Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype
    • Kumar B, Koul S, Khandrika L, Meacham RB, Koul HK. Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. Cancer Res. 2008; 68: 1777-85.
    • (2008) Cancer Res. , vol.68 , pp. 1777-1785
    • Kumar, B.1    Koul, S.2    Khandrika, L.3    Meacham, R.B.4    Koul, H.K.5
  • 146
    • 0034702847 scopus 로고    scopus 로고
    • NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells
    • Kikuchi H, Hikage M, Miyashita H, Fukumoto M. NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells. Gene 2000; 254: 237-43.
    • (2000) Gene , vol.254 , pp. 237-243
    • Kikuchi, H.1    Hikage, M.2    Miyashita, H.3    Fukumoto, M.4
  • 147
    • 80054968168 scopus 로고    scopus 로고
    • ROS generation via NOX4 and its utility in the cytological diagnosis of urothelial carcinoma of the urinary bladder
    • Shimada K, Fujii T, Anai S, Fujimoto K, Konishi N. ROS generation via NOX4 and its utility in the cytological diagnosis of urothelial carcinoma of the urinary bladder. BMC Urol. 2011; 11: 22.
    • (2011) BMC Urol. , vol.11 , pp. 22
    • Shimada, K.1    Fujii, T.2    Anai, S.3    Fujimoto, K.4    Konishi, N.5
  • 148
    • 84859763945 scopus 로고    scopus 로고
    • Right-side and left-side colon cancer follow different pathways to relapse
    • Bauer KM, Hummon AB, Buechler S. Right-side and left-side colon cancer follow different pathways to relapse. Mol. Carcinog. 2012; 51: 411-21.
    • (2012) Mol. Carcinog. , vol.51 , pp. 411-421
    • Bauer, K.M.1    Hummon, A.B.2    Buechler, S.3
  • 149
    • 77449129856 scopus 로고    scopus 로고
    • Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues
    • Weyemi U, Caillou B, Talbot M et al. Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues. Endocr. Relat. Cancer 2010; 17: 27-37.
    • (2010) Endocr. Relat. Cancer , vol.17 , pp. 27-37
    • Weyemi, U.1    Caillou, B.2    Talbot, M.3
  • 150
    • 84862908756 scopus 로고    scopus 로고
    • Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells
    • Huang WC, Li X, Liu J, Lin J, Chung LWK. Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells. Mol. Cancer Res. 2012; 10: 133-42.
    • (2012) Mol. Cancer Res. , vol.10 , pp. 133-142
    • Huang, W.C.1    Li, X.2    Liu, J.3    Lin, J.4    Chung, L.W.K.5
  • 151
    • 29144503697 scopus 로고    scopus 로고
    • Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia
    • Kamiguti AS, Serrander L, Lin K et al. Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia. J. Immunol. 2005; 175: 8424-30.
    • (2005) J. Immunol. , vol.175 , pp. 8424-8430
    • Kamiguti, A.S.1    Serrander, L.2    Lin, K.3
  • 152
    • 0018717734 scopus 로고
    • Some aspects of the pharmacology of diphenyleneiodonium, a bivalent iodine compound
    • Gatley S, Martin J. Some aspects of the pharmacology of diphenyleneiodonium, a bivalent iodine compound. Xenobiotica 1979; 9: 539-46.
    • (1979) Xenobiotica , vol.9 , pp. 539-546
    • Gatley, S.1    Martin, J.2
  • 154
    • 0023871970 scopus 로고
    • Chronic administration of the oral hypoglycaemic agent diphenyleneiodonium to rats: An animal model of impaired oxidative phosphorylation (mitochondrial myopathy)
    • Cooper JM, Petty RK, Hayes DJ, Morgan-Hughest JA, Clark JB. Chronic administration of the oral hypoglycaemic agent diphenyleneiodonium to rats: An animal model of impaired oxidative phosphorylation (mitochondrial myopathy). Biochem. Pharmacol. 1988; 37: 687-94.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 687-694
    • Cooper, J.M.1    Petty, R.K.2    Hayes, D.J.3    Morgan-Hughest, J.A.4    Clark, J.B.5
  • 155
    • 47149088045 scopus 로고    scopus 로고
    • Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase
    • Schäppi MG, Jaquet V, Belli DC, Krause K-H. Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase. Semin. Immunopathol. 2008; 30: 255-71.
    • (2008) Semin. Immunopathol. , vol.30 , pp. 255-271
    • Schäppi, M.G.1    Jaquet, V.2    Belli, D.C.3    Krause, K.-H.4


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