Methods to monitor classical protein-tyrosine phosphatase oxidation

FEBS Journal

Volumn 280, Issue 2, 2013, Pages 459-475

  Karisch, Robert ^a,b   Neel, Benjamin G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

activity based probes; cancer; dimedone; mass spectrometry; oxidation; protein tyrosine phosphatases; reactive oxygen species; signal transduction; sulfenic acid; tyrosyl phosphorylation

Indexed keywords

5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; BIOTIN; CYSTEINE; INDOLEACETIC ACID; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; PROTEIN ANTIBODY; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE SHP 2; REACTIVE OXYGEN METABOLITE; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ACTIVITY BASED PROBE; CATALYSIS; CYTOTOXICITY; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME METABOLISM; ENZYMIC BIOSENSOR; FUNCTIONAL PROTEOMICS; GENETIC CONSERVATION; HUMAN; IMMUNOSENSOR; INTERMETHOD COMPARISON; INTRACELLULAR SIGNALING; ISOTOPE LABELING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR PROBE; NONHUMAN; OXIDATION REDUCTION REACTION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROCESS MONITORING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN GEL BLOT ANALYSIS; PROTEIN PROCESSING; PROTEIN TARGETING; REVIEW;

CATALYSIS; CHEMISTRY TECHNIQUES, ANALYTICAL; CYSTEINE; HUMANS; ISOENZYMES; OXIDATION-REDUCTION; PROTEIN TYROSINE PHOSPHATASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84872787813     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08626.x     Document Type: Review

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