The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells

Biochemical Pharmacology

Volumn 81, Issue 7, 2011, Pages 917-924

  Sancho, Patricia ^a   Fabregat, Isabel ^a,b  

^a BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Hepatocellular carcinoma (HCC); NADPH oxidases; NOX; Proliferation; Reactive Oxygen Species (ROS)

Indexed keywords

ANTINEOPLASTIC AGENT; APOCYNIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; THYMIDINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VAS 2870;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG TARGETING; ENZYME INHIBITION; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BENZOXAZOLES; BLOTTING, WESTERN; CELL DIVISION; CELL LINE, TUMOR; DNA PRIMERS; ENZYME INHIBITORS; HUMANS; LIVER NEOPLASMS; NADPH OXIDASE; RATS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TRIAZOLES;

EID: 79952575436     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.01.007     Document Type: Article

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