Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+

Circulation Research

Volumn 83, Issue 7, 1998, Pages 730-737

  Al Mehdi, Abu B ^a   Zhao, Guochang ^a   Dodia, Chandra ^a   Tozawa, Kasumi ^a   Costa, Karen ^a   Muzykantov, Vladimir ^a   Ross, Chris ^b   Blecha, Frank ^b   Dinauer, Mary ^c   Fisher, Aron B ^a,d  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Bovine pulmonary artery endothelial cell; Diphenyliodonium; Gp91(phox); P47(phox); PR 39

Indexed keywords

ALLOPURINOL; DIPHENYLIODONIUM SALT; OXIDIZING AGENT; POTASSIUM; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SYNTHETIC PEPTIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOXIA; ARTICLE; CATTLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ISCHEMIA; KNOCKOUT MOUSE; LUNG; MALE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; REOXYGENATION;

EID: 0032487361     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.83.7.730     Document Type: Article

References (35)

1. Fisher AB, Dodia C, Tan Z, Ayene I, Eckenhoff RG. Oxygen-dependent lipid peroxidation during lung ischemia. J Clin Invest. 1991;88:674-679.
2. Al-Mehdi A, Shuman H, Fisher AB. Intracellular generation of reactive oxygen species during non-hypoxic lung ischemia. Am J Physiol. 1997; 270:L294-L300.
3. Zhao G, Al-Mehdi A, Fisher AB. Anoxia-reoxygenation versus ischemia in isolated rat lungs. Am J Physiol. 1997;273:L1112-L1117.
4. McCord JM. Oxygen-derived free radicals in post-ischemic tissue injury. N Engl J Med. 1985;312:159-163.
5. Al-Mehdi A, Zhao G, Fisher AB. ATP-independent membrane depolarization with ischemia in the oxygen-ventilated isolated rat lung. Am J Respir Cell Mol Biol. 1998;18:653-661.
6. +-induced membrane depolarization. J Cell Physiol. 1996;166:274-280.
7. +-induced depolarization in the isolated perfused lung. Free Radic Biol Med. 1997; 23:47-56.
8. Cross AR, Jones OT. The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils: specific labelling of a component polypeptide of the oxidase. Biochem J. 1986;237:111-116.
9. Clark RA. The human respiratory burst oxidase. J Infect Dis. 1990;161: 1140-1147.
10. DeLeo FR, Quinn MT. Assembly of the phagocyte NADH oxidase: molecular interaction of oxidase proteins. J Leukoc Biol. 1996;60: 677-691.
11. Shi J, Ross CR, Chengappa MM, Blecha F. Identification of a prolinearginine-rich antibacterial peptide from neutrophils that is analogous to PR-39, an antibacterial peptide from the small intestine. J Leukoc Biol. 1994;56:807-811.
12. phox. Proc Natl Acad Sci U S A. 1996;93: 6014-6018.
13. Pollock JD, Williams DA, Gifford MA, Li LL, Du X, Fisherman J, Orkin SH, Doerschuk CM, Dinauer MC. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte Superoxide production. Nat Genet. 1995;9:202-209.
14. phox may contribute to the generation of superoxide by an NADPH oxidase-like system in human fibroblasts. FEBS Lett. 1994; 355:178-182.
15. Fisher AB, Dodia C, Linask J. Perfusate composition and edema formation in isolated rat lungs. Exp Lung Res. 1980;1:13-21.
16. Al-Mehdi A, Shuman H, Fisher AB. Fluorescence microtopography of oxidative stress in lung ischemia-reperfusion. Lab Invest. 1994;70: 579-587.
17. Bradford MM. A rapid and sensitive method for quantitation of micrograrn quantities of protein utilizing the principle of protein dye binding. Anal Biochem. 1976;72:248-254.
18. Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol. 1978;52:302-310.
19. Voyta JC, Via DP, Butterfield CE, Zetter BR. Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein. J Cell biol. 1984;99:2034-2040.
20. Trinkle LS, Welhausen SR, McLeish KR. A simultaneous flow cytometric measurement of neutrophil phagocytosis and oxidative burst in whole blood. Diagn Clin Immunol. 1987;5:62-68.
21. Kobzik L, Godleski JJ, Brain JD. Oxidative metabolism in the alveolar macrophage: analysis by flow cytometry. J Leukoc Biol. 1990;47: 295-303.
22. Robertson FM, Beavis AJ, Oberyszyn TM, O'Connell SM, Dokidos A, Laskin DL, Laskin JD, Reiners JJ Jr. Production of hydrogen peroxide by murine epidermal keratinocytes following treatment with the tumor promoter 12-0-tetradecanoylphorbol-13-acetate. Cancer Res. 1990;50: 6062-6067.
23. Crow JP. Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species. Biol Chem. 1997; 1:145-157.
24. Jones SA, O'Donnell VB, Wood JD, Broughton JP, Hughes EJ, Jones OTG. Expression of phagocyte NADPH oxidase components in human endothelial cells. Am J Physiol. 1996;271:H1626-H1634.
25. Marshall C, Mamary AJ, Verhoeven AJ, Marshall BE. Pulmonary artery NADPH-oxidase is activated in hypoxic pulmonary vasoconstriction. Am J Respir Cell Mol Biol. 1996;15:633-644.
26. + channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines. Proc Natl Acad Sci U S A. 1996;93:13182-13187.
27. Lum H, Barr DA, Shaffer JR, Gordon RJ, Ezrin AM, Malik AB. Reoxygenation of endothelial cells increases permeability by oxidant-dependent mechanisms. Circ Res. 1992;70:991-998.
28. Zulueta JJ, Yu FS, Hertig IA, Thannickal VJ, Hassoun PM. Release of hydrogen peroxide in response to hypoxia-reoxygenation: role of an NAD(P)H oxidase-like enzyme in endothelial cell plasma membrane. Am J Respir Cell Mol Biol. 1995;12:41-49.
29. Zulueta JJ, Sawhney R, Yu FS, Cote CC, Hassoun PM. Intracellular generation of reactive oxygen species in endothelial cells exposed to anoxia-reoxygenation. Am J Physiol. 1997;272:L897-L902.
30. Kuroki M, Kamo N, Kobatake Y, Okimassu E, Utsumi K. Measurement of membrane potential in polymorphonuclear leukocytes and its changes during surface stimulation. Biochim Biophys Acta. 1982;693:326-334.
31. Kitagawa S, Johnston RB. Relationship between membrane potential changes and superoxide releasing capacity in resident and activated mouse peritoneal macrophages. J Immunol. 1985;35:3417-3423.
32. Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH-oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988;255:285-290.
33. + current in vascular endothelial cells. Nature. 1988;331:168-170.
34. Ayene SI, Dodia C, Fisher AB. Role of oxygen in oxidation of lipid and protein during ischemia/reperfusion in isolated perfused rat lung. Arch Biochem Biophys. 1992;296:183-189.
35. Zhao G, Ayene IS, Fisher AB. Role of iron in ischemia-reperfusion oxidative injury of rat lungs. Am J Respir Cell Mol Biol. 1997;16: 293-299.