-
1
-
-
84872225149
-
PGC1alpha and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders
-
doi: 10.1242/jcs.113662
-
Austin, S., and St-Pierre, J. (2012). PGC1alpha and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders. J. Cell Sci. 125, 4963-4971. doi: 10.1242/jcs.113662
-
(2012)
J. Cell Sci.
, vol.125
, pp. 4963-4971
-
-
Austin, S.1
St-Pierre, J.2
-
2
-
-
79959594483
-
Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation
-
doi: 10.1007/s00280-010-1441-7
-
Bugger, H., Guzman, C., Zechner, C., Palmeri, M., Russell, K. S., and Russell, R. R. 3rd. (2011). Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation. Cancer Chemother. Pharmacol. 67, 1381-1388. doi: 10.1007/s00280-010-1441-7
-
(2011)
Cancer Chemother. Pharmacol.
, vol.67
, pp. 1381-1388
-
-
Bugger, H.1
Guzman, C.2
Zechner, C.3
Palmeri, M.4
Russell, K.S.5
Russell III, R.R.6
-
3
-
-
84867181855
-
A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila
-
doi: 10.1534/genetics.112.143719
-
Chen, S., Oliveira, M. T., Sanz, A., Kemppainen, E., Fukuoh, A., Schlicht, B., et al. (2012). A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila. Genetics 192, 483-493. doi: 10.1534/genetics.112.143719
-
(2012)
Genetics
, vol.192
, pp. 483-493
-
-
Chen, S.1
Oliveira, M.T.2
Sanz, A.3
Kemppainen, E.4
Fukuoh, A.5
Schlicht, B.6
-
4
-
-
0035815414
-
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
-
doi: 10.1126/science.1057991
-
Clancy, D. J., Gems, D., Harshman, L. G., Oldham, S., Stocker, H., Hafen, E., et al. (2001). Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292, 104-106. doi: 10.1126/science.1057991
-
(2001)
Science
, vol.292
, pp. 104-106
-
-
Clancy, D.J.1
Gems, D.2
Harshman, L.G.3
Oldham, S.4
Stocker, H.5
Hafen, E.6
-
5
-
-
67249133451
-
Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia
-
doi: 10.1093/hmg/ddp183
-
Coppola, G., Marmolino, D., Lu, D., Wang, Q., Cnop, M., Rai, M., et al. (2009). Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia. Hum. Mol. Genet. 18, 2452-2461. doi: 10.1093/hmg/ddp183
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2452-2461
-
-
Coppola, G.1
Marmolino, D.2
Lu, D.3
Wang, Q.4
Cnop, M.5
Rai, M.6
-
6
-
-
77951176737
-
Extending healthy life span-from yeast to humans
-
doi: 10.1126/science.1172539
-
Fontana, L., Partridge, L., and Longo, V. D. (2010). Extending healthy life span-from yeast to humans. Science 328, 321-326. doi: 10.1126/science.1172539
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
7
-
-
34248207609
-
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO
-
doi: 10.1152/physiolgenomics.00061.2006
-
Gershman, B., Puig, O., Hang, L., Peitzsch, R. M., Tatar, M., and Garofalo, R. S. (2007). High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiol. Genomics 29, 24-34. doi: 10.1152/physiolgenomics.00061.2006
-
(2007)
Physiol. Genomics
, vol.29
, pp. 24-34
-
-
Gershman, B.1
Puig, O.2
Hang, L.3
Peitzsch, R.M.4
Tatar, M.5
Garofalo, R.S.6
-
8
-
-
33845596500
-
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
-
doi: 10.1210/er.2006-0037
-
Handschin, C., and Spiegelman, B. M. (2006). Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr. Rev. 27, 728-735. doi: 10.1210/er.2006-0037
-
(2006)
Endocr. Rev.
, vol.27
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
9
-
-
73349138892
-
Regulation of tissue growth through nutrient sensing
-
doi: 10.1146/annurev-genet-102108-134815
-
Hietakangas, V., and Cohen, S. M. (2009). Regulation of tissue growth through nutrient sensing. Annu. Rev. Genet. 43, 389-410. doi: 10.1146/annurev-genet-102108-134815
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 389-410
-
-
Hietakangas, V.1
Cohen, S.M.2
-
10
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
-
doi: 10.1016/j.cub.2004.03.059
-
Kapahi, P., Zid, B. M., Harper, T., Koslover, D., Sapin, V., and Benzer, S. (2004). Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 14, 885-890. doi: 10.1016/j.cub.2004.03.059
-
(2004)
Curr. Biol.
, vol.14
, pp. 885-890
-
-
Kapahi, P.1
Zid, B.M.2
Harper, T.3
Koslover, D.4
Sapin, V.5
Benzer, S.6
-
11
-
-
77950200010
-
The genetics of ageing
-
doi: 10.1038/nature08980
-
Kenyon, C. J. (2010). The genetics of ageing. Nature 464, 504-512. doi: 10.1038/nature08980
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
12
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
-
doi: 10.1038/nm1044
-
Koo, S. H., Satoh, H., Herzig, S., Lee, C. H., Hedrick, S., Kulkarni, R., et al. (2004). PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat. Med. 10, 530-534. doi: 10.1038/nm1044
-
(2004)
Nat. Med.
, vol.10
, pp. 530-534
-
-
Koo, S.H.1
Satoh, H.2
Herzig, S.3
Lee, C.H.4
Hedrick, S.5
Kulkarni, R.6
-
13
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
doi: 10.1016/j.cmet.2005.05.004
-
Lin, J., Handschin, C., and Spiegelman, B. M. (2005). Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1, 361-370. doi: 10.1016/j.cmet.2005.05.004
-
(2005)
Cell Metab.
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
14
-
-
79953186142
-
PGC-1 coactivators in the control of energy metabolism
-
doi: 10.1093/abbs/gmr007
-
Liu, C., and Lin, J. D. (2011). PGC-1 coactivators in the control of energy metabolism. Acta Biochim. Biophys. Sin. (Shanghai) 43, 248-257. doi: 10.1093/abbs/gmr007
-
(2011)
Acta Biochim. Biophys. Sin. (Shanghai)
, vol.43
, pp. 248-257
-
-
Liu, C.1
Lin, J.D.2
-
15
-
-
1842740359
-
A conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP
-
doi: 10.1074/jbc.M310188200
-
Matsuda, S., Harries, J. C., Viskaduraki, M., Troke, P. J., Kindle, K. B., Ryan, C., et al. (2004). A conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP. J. Biol. Chem. 279, 14055-14064. doi: 10.1074/jbc.M310188200
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14055-14064
-
-
Matsuda, S.1
Harries, J.C.2
Viskaduraki, M.3
Troke, P.J.4
Kindle, K.B.5
Ryan, C.6
-
16
-
-
0033638283
-
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
-
doi: 10.1016/S1097-2765(00)00031-9
-
Monsalve, M., Wu, Z., Adelmant, G., Puigserver, P., Fan, M., and Spiegelman, B. M. (2000). Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol. Cell 6, 307-316. doi: 10.1016/S1097-2765(00)00031-9
-
(2000)
Mol. Cell
, vol.6
, pp. 307-316
-
-
Monsalve, M.1
Wu, Z.2
Adelmant, G.3
Puigserver, P.4
Fan, M.5
Spiegelman, B.M.6
-
17
-
-
84884970596
-
Spargel/dPGC-1 is a new downstream effector in the insulin-TOR signaling pathway in Drosophila
-
doi: 10.1534/genetics.113.154583
-
Mukherjee, S., and Duttaroy, A. (2013). Spargel/dPGC-1 is a new downstream effector in the insulin-TOR signaling pathway in Drosophila. Genetics 195, 433-441. doi: 10.1534/genetics.113.154583
-
(2013)
Genetics
, vol.195
, pp. 433-441
-
-
Mukherjee, S.1
Duttaroy, A.2
-
18
-
-
79954628932
-
Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network
-
doi: 10.1016/j.exger.2010.09.003
-
Partridge, L., Alic, N., Bjedov, I., and Piper, M. D. (2011). Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network. Exp. Gerontol. 46, 376-381. doi: 10.1016/j.exger.2010.09.003
-
(2011)
Exp. Gerontol.
, vol.46
, pp. 376-381
-
-
Partridge, L.1
Alic, N.2
Bjedov, I.3
Piper, M.D.4
-
19
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
doi: 10.1038/nature01667
-
Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., et al. (2003). Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423, 550-555. doi: 10.1038/nature01667
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
-
20
-
-
0037326196
-
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator
-
doi: 10.1210/er.2002-0012
-
Puigserver, P., and Spiegelman, B. M. (2003). Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24, 78-90. doi: 10.1210/er.2002-0012
-
(2003)
Endocr. Rev.
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
21
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
doi: 10.1016/S0092-8674(00)81410-5
-
Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., and Spiegelman, B. M. (1998). A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839. doi: 10.1016/S0092-8674(00)81410-5
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
22
-
-
80455143200
-
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
-
doi: 10.1016/j.cmet.2011.09.013
-
Rera, M., Bahadorani, S., Cho, J., Koehler, C. L., Ulgherait, M., Hur, J. H., et al. (2011). Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab. 14, 623-634. doi: 10.1016/j.cmet.2011.09.013
-
(2011)
Cell Metab.
, vol.14
, pp. 623-634
-
-
Rera, M.1
Bahadorani, S.2
Cho, J.3
Koehler, C.L.4
Ulgherait, M.5
Hur, J.H.6
-
23
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
doi: 10.1016/j.cell.2006.09.024
-
St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J. M., Rhee, J., Jager, S., et al. (2006). Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127, 397-408. doi: 10.1016/j.cell.2006.09.024
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
-
24
-
-
0034947869
-
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin
-
doi: 10.1128/MCB.21.15.5050-5062.2001
-
Takano, A., Usui, I., Haruta, T., Kawahara, J., Uno, T., Iwata, M., et al. (2001). Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin. Mol. Cell. Biol. 21, 5050-5062. doi: 10.1128/MCB.21.15.5050-5062.2001
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5050-5062
-
-
Takano, A.1
Usui, I.2
Haruta, T.3
Kawahara, J.4
Uno, T.5
Iwata, M.6
-
25
-
-
0035815445
-
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
-
doi: 10.1126/science.1057987
-
Tatar, M., Kopelman, A., Epstein, D., Tu, M. P., Yin, C. M., and Garofalo, R. S. (2001). A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292, 107-110. doi: 10.1126/science.1057987
-
(2001)
Science
, vol.292
, pp. 107-110
-
-
Tatar, M.1
Kopelman, A.2
Epstein, D.3
Tu, M.P.4
Yin, C.M.5
Garofalo, R.S.6
-
26
-
-
75649131899
-
The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling
-
doi: 10.1038/emboj.2009.330
-
Tiefenbock, S. K., Baltzer, C., Egli, N. A., and Frei, C. (2010). The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling. EMBO J. 29, 171-183. doi: 10.1038/emboj.2009.330
-
(2010)
EMBO J.
, vol.29
, pp. 171-183
-
-
Tiefenbock, S.K.1
Baltzer, C.2
Egli, N.A.3
Frei, C.4
-
27
-
-
67651023133
-
A supertree analysis and literature review of the genus Drosophila and closely related genera (Diptera, Drosophilidae)
-
doi: 10.1163/187631208788784237
-
van der Linde, K., and Houle, D. (2008). A supertree analysis and literature review of the genus Drosophila and closely related genera (Diptera, Drosophilidae). Insect. Syst. Evol. 39, 241-267. doi: 10.1163/187631208788784237
-
(2008)
Insect. Syst. Evol.
, vol.39
, pp. 241-267
-
-
van der Linde, K.1
Houle, D.2
-
28
-
-
0642367846
-
Genetics: influence of TOR kinase on lifespan in C
-
doi: 10.1038/426620a
-
Vellai, T., Takacs-Vellai, K., Zhang, Y., Kovacs, A. L., Orosz, L., and Muller, F. (2003). Genetics: influence of TOR kinase on lifespan in C. elegans. Nature 426, 620. doi: 10.1038/426620a
-
(2003)
elegans. Nature
, vol.426
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.L.4
Orosz, L.5
Muller, F.6
-
29
-
-
34848903026
-
A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription
-
doi: 10.1111/j.1742-4658.2007.06062.x
-
Wang, J., Li, Y., Zhang, M., Liu, Z., Wu, C., Yuan, H., et al. (2007). A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription. FEBS J. 274, 5370-5381. doi: 10.1111/j.1742-4658.2007.06062.x
-
(2007)
FEBS J.
, vol.274
, pp. 5370-5381
-
-
Wang, J.1
Li, Y.2
Zhang, M.3
Liu, Z.4
Wu, C.5
Yuan, H.6
-
30
-
-
78649508058
-
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
-
doi: 10.1016/j.cmet.2010.11.008
-
Zechner, C., Lai, L., Zechner, J. F., Geng, T., Yan, Z., Rumsey, J. W., et al. (2010). Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab. 12, 633-642. doi: 10.1016/j.cmet.2010.11.008
-
(2010)
Cell Metab.
, vol.12
, pp. 633-642
-
-
Zechner, C.1
Lai, L.2
Zechner, J.F.3
Geng, T.4
Yan, Z.5
Rumsey, J.W.6
|