메뉴 건너뛰기




Volumn 5, Issue JUL, 2014, Pages

Emerging functional similarities and divergences between Drosophila Spargel/dPGC-1 and mammalian PGC-1 protein

Author keywords

Drosophila; Mitochondria; Oogenesis; PGC 1; RNA processing

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE; INSULIN; MANGANESE SUPEROXIDE DISMUTASE; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2;

EID: 84906233839     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2014.00216     Document Type: Article
Times cited : (20)

References (30)
  • 1
    • 84872225149 scopus 로고    scopus 로고
    • PGC1alpha and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders
    • doi: 10.1242/jcs.113662
    • Austin, S., and St-Pierre, J. (2012). PGC1alpha and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders. J. Cell Sci. 125, 4963-4971. doi: 10.1242/jcs.113662
    • (2012) J. Cell Sci. , vol.125 , pp. 4963-4971
    • Austin, S.1    St-Pierre, J.2
  • 2
    • 79959594483 scopus 로고    scopus 로고
    • Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation
    • doi: 10.1007/s00280-010-1441-7
    • Bugger, H., Guzman, C., Zechner, C., Palmeri, M., Russell, K. S., and Russell, R. R. 3rd. (2011). Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation. Cancer Chemother. Pharmacol. 67, 1381-1388. doi: 10.1007/s00280-010-1441-7
    • (2011) Cancer Chemother. Pharmacol. , vol.67 , pp. 1381-1388
    • Bugger, H.1    Guzman, C.2    Zechner, C.3    Palmeri, M.4    Russell, K.S.5    Russell III, R.R.6
  • 3
    • 84867181855 scopus 로고    scopus 로고
    • A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila
    • doi: 10.1534/genetics.112.143719
    • Chen, S., Oliveira, M. T., Sanz, A., Kemppainen, E., Fukuoh, A., Schlicht, B., et al. (2012). A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila. Genetics 192, 483-493. doi: 10.1534/genetics.112.143719
    • (2012) Genetics , vol.192 , pp. 483-493
    • Chen, S.1    Oliveira, M.T.2    Sanz, A.3    Kemppainen, E.4    Fukuoh, A.5    Schlicht, B.6
  • 4
    • 0035815414 scopus 로고    scopus 로고
    • Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
    • doi: 10.1126/science.1057991
    • Clancy, D. J., Gems, D., Harshman, L. G., Oldham, S., Stocker, H., Hafen, E., et al. (2001). Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292, 104-106. doi: 10.1126/science.1057991
    • (2001) Science , vol.292 , pp. 104-106
    • Clancy, D.J.1    Gems, D.2    Harshman, L.G.3    Oldham, S.4    Stocker, H.5    Hafen, E.6
  • 5
    • 67249133451 scopus 로고    scopus 로고
    • Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia
    • doi: 10.1093/hmg/ddp183
    • Coppola, G., Marmolino, D., Lu, D., Wang, Q., Cnop, M., Rai, M., et al. (2009). Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia. Hum. Mol. Genet. 18, 2452-2461. doi: 10.1093/hmg/ddp183
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 2452-2461
    • Coppola, G.1    Marmolino, D.2    Lu, D.3    Wang, Q.4    Cnop, M.5    Rai, M.6
  • 6
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • doi: 10.1126/science.1172539
    • Fontana, L., Partridge, L., and Longo, V. D. (2010). Extending healthy life span-from yeast to humans. Science 328, 321-326. doi: 10.1126/science.1172539
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 7
    • 34248207609 scopus 로고    scopus 로고
    • High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO
    • doi: 10.1152/physiolgenomics.00061.2006
    • Gershman, B., Puig, O., Hang, L., Peitzsch, R. M., Tatar, M., and Garofalo, R. S. (2007). High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiol. Genomics 29, 24-34. doi: 10.1152/physiolgenomics.00061.2006
    • (2007) Physiol. Genomics , vol.29 , pp. 24-34
    • Gershman, B.1    Puig, O.2    Hang, L.3    Peitzsch, R.M.4    Tatar, M.5    Garofalo, R.S.6
  • 8
    • 33845596500 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
    • doi: 10.1210/er.2006-0037
    • Handschin, C., and Spiegelman, B. M. (2006). Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr. Rev. 27, 728-735. doi: 10.1210/er.2006-0037
    • (2006) Endocr. Rev. , vol.27 , pp. 728-735
    • Handschin, C.1    Spiegelman, B.M.2
  • 9
    • 73349138892 scopus 로고    scopus 로고
    • Regulation of tissue growth through nutrient sensing
    • doi: 10.1146/annurev-genet-102108-134815
    • Hietakangas, V., and Cohen, S. M. (2009). Regulation of tissue growth through nutrient sensing. Annu. Rev. Genet. 43, 389-410. doi: 10.1146/annurev-genet-102108-134815
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 389-410
    • Hietakangas, V.1    Cohen, S.M.2
  • 10
    • 3042648746 scopus 로고    scopus 로고
    • Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
    • doi: 10.1016/j.cub.2004.03.059
    • Kapahi, P., Zid, B. M., Harper, T., Koslover, D., Sapin, V., and Benzer, S. (2004). Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 14, 885-890. doi: 10.1016/j.cub.2004.03.059
    • (2004) Curr. Biol. , vol.14 , pp. 885-890
    • Kapahi, P.1    Zid, B.M.2    Harper, T.3    Koslover, D.4    Sapin, V.5    Benzer, S.6
  • 11
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • doi: 10.1038/nature08980
    • Kenyon, C. J. (2010). The genetics of ageing. Nature 464, 504-512. doi: 10.1038/nature08980
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 12
    • 2442701392 scopus 로고    scopus 로고
    • PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
    • doi: 10.1038/nm1044
    • Koo, S. H., Satoh, H., Herzig, S., Lee, C. H., Hedrick, S., Kulkarni, R., et al. (2004). PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat. Med. 10, 530-534. doi: 10.1038/nm1044
    • (2004) Nat. Med. , vol.10 , pp. 530-534
    • Koo, S.H.1    Satoh, H.2    Herzig, S.3    Lee, C.H.4    Hedrick, S.5    Kulkarni, R.6
  • 13
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • doi: 10.1016/j.cmet.2005.05.004
    • Lin, J., Handschin, C., and Spiegelman, B. M. (2005). Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1, 361-370. doi: 10.1016/j.cmet.2005.05.004
    • (2005) Cell Metab. , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 14
    • 79953186142 scopus 로고    scopus 로고
    • PGC-1 coactivators in the control of energy metabolism
    • doi: 10.1093/abbs/gmr007
    • Liu, C., and Lin, J. D. (2011). PGC-1 coactivators in the control of energy metabolism. Acta Biochim. Biophys. Sin. (Shanghai) 43, 248-257. doi: 10.1093/abbs/gmr007
    • (2011) Acta Biochim. Biophys. Sin. (Shanghai) , vol.43 , pp. 248-257
    • Liu, C.1    Lin, J.D.2
  • 15
    • 1842740359 scopus 로고    scopus 로고
    • A conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP
    • doi: 10.1074/jbc.M310188200
    • Matsuda, S., Harries, J. C., Viskaduraki, M., Troke, P. J., Kindle, K. B., Ryan, C., et al. (2004). A conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP. J. Biol. Chem. 279, 14055-14064. doi: 10.1074/jbc.M310188200
    • (2004) J. Biol. Chem. , vol.279 , pp. 14055-14064
    • Matsuda, S.1    Harries, J.C.2    Viskaduraki, M.3    Troke, P.J.4    Kindle, K.B.5    Ryan, C.6
  • 16
    • 0033638283 scopus 로고    scopus 로고
    • Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
    • doi: 10.1016/S1097-2765(00)00031-9
    • Monsalve, M., Wu, Z., Adelmant, G., Puigserver, P., Fan, M., and Spiegelman, B. M. (2000). Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol. Cell 6, 307-316. doi: 10.1016/S1097-2765(00)00031-9
    • (2000) Mol. Cell , vol.6 , pp. 307-316
    • Monsalve, M.1    Wu, Z.2    Adelmant, G.3    Puigserver, P.4    Fan, M.5    Spiegelman, B.M.6
  • 17
    • 84884970596 scopus 로고    scopus 로고
    • Spargel/dPGC-1 is a new downstream effector in the insulin-TOR signaling pathway in Drosophila
    • doi: 10.1534/genetics.113.154583
    • Mukherjee, S., and Duttaroy, A. (2013). Spargel/dPGC-1 is a new downstream effector in the insulin-TOR signaling pathway in Drosophila. Genetics 195, 433-441. doi: 10.1534/genetics.113.154583
    • (2013) Genetics , vol.195 , pp. 433-441
    • Mukherjee, S.1    Duttaroy, A.2
  • 18
    • 79954628932 scopus 로고    scopus 로고
    • Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network
    • doi: 10.1016/j.exger.2010.09.003
    • Partridge, L., Alic, N., Bjedov, I., and Piper, M. D. (2011). Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network. Exp. Gerontol. 46, 376-381. doi: 10.1016/j.exger.2010.09.003
    • (2011) Exp. Gerontol. , vol.46 , pp. 376-381
    • Partridge, L.1    Alic, N.2    Bjedov, I.3    Piper, M.D.4
  • 19
    • 0038187621 scopus 로고    scopus 로고
    • Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
    • doi: 10.1038/nature01667
    • Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., et al. (2003). Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423, 550-555. doi: 10.1038/nature01667
    • (2003) Nature , vol.423 , pp. 550-555
    • Puigserver, P.1    Rhee, J.2    Donovan, J.3    Walkey, C.J.4    Yoon, J.C.5    Oriente, F.6
  • 20
    • 0037326196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator
    • doi: 10.1210/er.2002-0012
    • Puigserver, P., and Spiegelman, B. M. (2003). Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24, 78-90. doi: 10.1210/er.2002-0012
    • (2003) Endocr. Rev. , vol.24 , pp. 78-90
    • Puigserver, P.1    Spiegelman, B.M.2
  • 21
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • doi: 10.1016/S0092-8674(00)81410-5
    • Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., and Spiegelman, B. M. (1998). A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839. doi: 10.1016/S0092-8674(00)81410-5
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 22
    • 80455143200 scopus 로고    scopus 로고
    • Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
    • doi: 10.1016/j.cmet.2011.09.013
    • Rera, M., Bahadorani, S., Cho, J., Koehler, C. L., Ulgherait, M., Hur, J. H., et al. (2011). Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab. 14, 623-634. doi: 10.1016/j.cmet.2011.09.013
    • (2011) Cell Metab. , vol.14 , pp. 623-634
    • Rera, M.1    Bahadorani, S.2    Cho, J.3    Koehler, C.L.4    Ulgherait, M.5    Hur, J.H.6
  • 23
    • 33749999530 scopus 로고    scopus 로고
    • Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
    • doi: 10.1016/j.cell.2006.09.024
    • St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J. M., Rhee, J., Jager, S., et al. (2006). Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127, 397-408. doi: 10.1016/j.cell.2006.09.024
    • (2006) Cell , vol.127 , pp. 397-408
    • St-Pierre, J.1    Drori, S.2    Uldry, M.3    Silvaggi, J.M.4    Rhee, J.5    Jager, S.6
  • 24
    • 0034947869 scopus 로고    scopus 로고
    • Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin
    • doi: 10.1128/MCB.21.15.5050-5062.2001
    • Takano, A., Usui, I., Haruta, T., Kawahara, J., Uno, T., Iwata, M., et al. (2001). Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin. Mol. Cell. Biol. 21, 5050-5062. doi: 10.1128/MCB.21.15.5050-5062.2001
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5050-5062
    • Takano, A.1    Usui, I.2    Haruta, T.3    Kawahara, J.4    Uno, T.5    Iwata, M.6
  • 25
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
    • doi: 10.1126/science.1057987
    • Tatar, M., Kopelman, A., Epstein, D., Tu, M. P., Yin, C. M., and Garofalo, R. S. (2001). A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292, 107-110. doi: 10.1126/science.1057987
    • (2001) Science , vol.292 , pp. 107-110
    • Tatar, M.1    Kopelman, A.2    Epstein, D.3    Tu, M.P.4    Yin, C.M.5    Garofalo, R.S.6
  • 26
    • 75649131899 scopus 로고    scopus 로고
    • The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling
    • doi: 10.1038/emboj.2009.330
    • Tiefenbock, S. K., Baltzer, C., Egli, N. A., and Frei, C. (2010). The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling. EMBO J. 29, 171-183. doi: 10.1038/emboj.2009.330
    • (2010) EMBO J. , vol.29 , pp. 171-183
    • Tiefenbock, S.K.1    Baltzer, C.2    Egli, N.A.3    Frei, C.4
  • 27
    • 67651023133 scopus 로고    scopus 로고
    • A supertree analysis and literature review of the genus Drosophila and closely related genera (Diptera, Drosophilidae)
    • doi: 10.1163/187631208788784237
    • van der Linde, K., and Houle, D. (2008). A supertree analysis and literature review of the genus Drosophila and closely related genera (Diptera, Drosophilidae). Insect. Syst. Evol. 39, 241-267. doi: 10.1163/187631208788784237
    • (2008) Insect. Syst. Evol. , vol.39 , pp. 241-267
    • van der Linde, K.1    Houle, D.2
  • 29
    • 34848903026 scopus 로고    scopus 로고
    • A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription
    • doi: 10.1111/j.1742-4658.2007.06062.x
    • Wang, J., Li, Y., Zhang, M., Liu, Z., Wu, C., Yuan, H., et al. (2007). A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription. FEBS J. 274, 5370-5381. doi: 10.1111/j.1742-4658.2007.06062.x
    • (2007) FEBS J. , vol.274 , pp. 5370-5381
    • Wang, J.1    Li, Y.2    Zhang, M.3    Liu, Z.4    Wu, C.5    Yuan, H.6
  • 30
    • 78649508058 scopus 로고    scopus 로고
    • Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
    • doi: 10.1016/j.cmet.2010.11.008
    • Zechner, C., Lai, L., Zechner, J. F., Geng, T., Yan, Z., Rumsey, J. W., et al. (2010). Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab. 12, 633-642. doi: 10.1016/j.cmet.2010.11.008
    • (2010) Cell Metab. , vol.12 , pp. 633-642
    • Zechner, C.1    Lai, L.2    Zechner, J.F.3    Geng, T.4    Yan, Z.5    Rumsey, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.